Cardiac ischemia oxidizes regulatory thiols on ryanodine receptors: Captopril acts as a reducing agent to improve CA2+ uptake by ischemic sarcoplasmic reticulum

Journal of Cardiovascular Pharmacology

Volumn 36, Issue 5, 2000, Pages 656-668

  Menshikova, Elizabeth V ^a   Salama, Guy ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin converting enzyme; Canine and human SR; Captopril; Cardiac ischemia; Nitric oxide; Reactive disulfide compounds; Ryanodine receptors; Sarcoplasmic reticulum

Indexed keywords

ADENOSINE TRIPHOSPHATASE; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DISULFIDE; NITRIC OXIDE; RYANODINE RECEPTOR; THIOL DERIVATIVE;

ANIMAL TISSUE; ARTICLE; CALCIUM TRANSPORT; CONTROLLED STUDY; DOG; DRUG ACTIVITY; DRUG EFFECT; DRUG POTENCY; ENZYME ACTIVITY; HEART MUSCLE ISCHEMIA; HUMAN; HUMAN TISSUE; NONHUMAN; OXIDATION; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM;

EID: 0033753805     PISSN: 01602446     EISSN: None     Source Type: Journal    
DOI: 10.1097/00005344-200011000-00016     Document Type: Article

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