Increased short-term variability of repolarization predicts d-sotalol-induced torsades de pointes in dogs

Circulation

Volumn 110, Issue 16, 2004, Pages 2453-2459

  Thomsen, Morten B ^a,b   Verduyn, S Cora ^a   Stengl, Milan ^a,b   Beekman, Jet D M ^a,b   De Pater, Geert ^a   Van Opstal, Jurren ^a   Volders, Paul G A ^a   Vos, Marc A ^a,b,c  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c Department of Medical Physiology ^*  (Netherlands)

Author keywords

Action potentials; Arrhythmia; Torsades de pointes

Indexed keywords

AMIODARONE; SOTALOL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATRIOVENTRICULAR BLOCK; CELL ISOLATION; CONTROLLED STUDY; DIAGNOSTIC VALUE; DOSE RESPONSE; DRUG INDUCED DISEASE; EXTRASYSTOLE; HEART ARRHYTHMIA; HEART FUNCTION TEST; HEART MUSCLE POTENTIAL; HEART RATE VARIABILITY; HEART REPOLARIZATION; HEART VENTRICLE REMODELING; HEART VENTRICLE WALL; NONHUMAN; PREDICTION; PRIORITY JOURNAL; QT PROLONGATION; QUANTITATIVE DIAGNOSIS; RISK ASSESSMENT; SHORT TERM VARIABILITY; TORSADE DES POINTES;

ACTION POTENTIALS; ADRENERGIC BETA-ANTAGONISTS; ANIMALS; CARDIAC COMPLEXES, PREMATURE; CHRONIC DISEASE; DISEASE SUSCEPTIBILITY; DOGS; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROCARDIOGRAPHY; FEMALE; HEART BLOCK; HEART CONDUCTION SYSTEM; HEART VENTRICLES; MALE; PREDICTIVE VALUE OF TESTS; SOTALOL; TORSADES DE POINTES;

EID: 6444237997     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000145162.64183.C8     Document Type: Article

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