High-Resolution Mass Spectrometry and Drug Metabolite Identification

Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications

Volumn , Issue , 2011, Pages 407-448

  Mortishire Smith, Russell J ^a   Zhang, Haiying ^b   Bateman, Kevin P ^c  

^a JANSSEN RESEARCH FOUNDATION   (Belgium)

^b BRISTOL MYERS SQUIBB   (United States)

^c MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

High resolution mass spectrometry (HRMS) technology techniques for improving selectivity in metabolite detection, with sensitivity limitations being overcome; High resolution mass spectrometry and drug metabolite identification drug metabolite identification, critical to drug discovery; HRMS into drug metabolism work flow catalyzing new approaches, metabolites identified in complex data sets, one being mass defect filtration

Indexed keywords

EID: 84878510036     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470929278.ch13     Document Type: Chapter

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