Metabolism of 8-prenylnaringenin, a potent phytoestrogen from hops (Humulus lupulus), by human liver microsomes

Drug Metabolism and Disposition

Volumn 32, Issue 2, 2004, Pages 272-279

  Nikolic, Dejan ^a   Li, Yongmei ^a   Chadwick, Lucas R ^a   Grubjesic, Simonida ^a   Schwab, Pia ^b   Metz, Peter ^b   Van Breemen, Richard B ^a  

^a UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 8 PRENYLNARINGENIN; 4 [5,7 DIHYDROXY 2 (4 HYDROXYPHENYL) 4 OXO 3,4 DIHYDRO 2H CHROMEN 8 YL] 2 METHYL 2 BUTENAL; 5,4' DIHYDROXY 2'',2'' DIMETHYLPYRANO [7,8:6'',5'']FLAVANONE; 5,4' DIHYDROXY [2'' (1 HYDROXY 1 METHYLETHYL)DIHYDROFURANO][5'',4'':7,8]FLAVANONE; 5,7 DIHYDROXY 8 (4 HYDROXY 3 METHYL 2 BUTENYL) 2 (4 HYDROXYPHENYL) 2,3 DIHYDRO 4H CHROMEN 4 ONE; 5,7,4' TRIHYDROXY 8 (2 HYDROXY 3 METHYLBUT 3 ENYL)FLAVANONE; 8 PRENYLAPIGENIN; 8 PRENYLCHROMONE; 8 PRENYLNARINGENIN; 8 PRENYLNARINGENIN ALDEHYDE; FLAVANONE; FLAVONOID; PHYTOESTROGEN; PLANT EXTRACT; UNCLASSIFIED DRUG;

ARTICLE; BIOTRANSFORMATION; DRUG ISOLATION; DRUG METABOLISM; ESTROGEN ACTIVITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HUMULUS; HUMULUS LUPULUS; LIVER MICROSOME; MASS SPECTROMETRY; METABOLITE; NONHUMAN; PHYTOCHEMISTRY; PRIORITY JOURNAL;

CHROMATOGRAPHY, LIQUID; FLAVANONES; HUMANS; HUMULUS; ISOFLAVONES; KINETICS; MASS SPECTROMETRY; MICROSOMES, LIVER; PHYTOESTROGENS; PLANT PREPARATIONS;

HUMULUS; HUMULUS LUPULUS;

EID: 0842347421     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.32.2.272     Document Type: Article

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