Rapid screening and characterization of drug metabolites using a multiple ion monitoring-dependent MS/MS acquisition method on a hybrid triple quadrupole-linear ion trap mass spectrometer

Journal of Mass Spectrometry

Volumn 43, Issue 10, 2008, Pages 1364-1375

  Yao, Ming ^a   Ma, Li ^a   Humphreys, W Griffith ^a   Zhu, Mingshe ^a  

^a BRISTOL MYERS SQUIBB   (United States)

Author keywords

LTQ; Metabolite screening; MIM; MRM; Multiple ion monitoring; Multiple reaction monitoring; Q TRAP; Ritonavir; Triple quadrupole linear ion trap mass spectrometry

Indexed keywords

ELECTROLYSIS; ELECTRON TRAPS; FORECASTING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IONS; MAGNETIC PROPERTIES; MAGNETIC SUSCEPTIBILITY; MASS SPECTROMETERS; MASS SPECTROMETRY; MERGERS AND ACQUISITIONS; METABOLITES; MIM DEVICES; SPECTROMETERS; SPECTROMETRY;

LTQ; METABOLITE SCREENING; MIM; MRM; MULTIPLE ION MONITORING; MULTIPLE REACTION MONITORING; Q TRAP; RITONAVIR; TRIPLE QUADRUPOLE-LINEAR ION TRAP MASS SPECTROMETRY;

BIOMOLECULES;

DRUG METABOLITE; RITONAVIR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; ION MONITORING; ION TRAP MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; LIVER CELL; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ANTI-HIV AGENTS; BIOTRANSFORMATION; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG RESIDUES; HEPATOCYTES; INDICATORS AND REAGENTS; MASS SPECTROMETRY; PHARMACEUTICAL PREPARATIONS; RATS; RITONAVIR;

RATTUS;

EID: 55249123849     PISSN: 10765174     EISSN: 10969888     Source Type: Journal    
DOI: 10.1002/jms.1412     Document Type: Article

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