Bromobalhimycin and chlorobromobalhimycins - Illuminating the potential of halogenases in glycopeptide antibiotic biosyntheses

ChemBioChem

Volumn 4, Issue 7, 2003, Pages 658-662

  Bister, Bojan ^a   Bischoff, Daniel ^a   Nicholson, Graeme J ^a   Stockert, Sigrid ^a   Wink, Joachim ^d   Brunati, Cristina ^c   Donadio, Stefano ^c   Pelzer, Stefan ^a,b   Wohlleben, Wolfgang ^a   Süssmuth, Roderich D ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

^b MerLion Pharmaceuticals GmbH   (Germany)

^c Biosearch Italia   (Italy)

^d SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

Antibiotics; Balhimycin; Bromine; Glycopeptides; Halogenase

Indexed keywords

ANTIBIOTIC AGENT; BACTERIAL ENZYME; BROMINE; BROMOBALHIMYCIN; CHLORINE; CHLOROBROMOBALHIMYCIN; FLUORINE; GLYCOPEPTIDE ANTIBIOTIC; HALOGEN; HALOGENASE; HYDROGEN; UNCLASSIFIED DRUG;

ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIUM CULTURE; CONCENTRATION RESPONSE; CULTURE MEDIUM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVITY; FERMENTATION MEDIUM; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

ANTI-BACTERIAL AGENTS; GRAM-POSITIVE BACTERIA; HYDROCARBONS, BROMINATED; HYDROCARBONS, CHLORINATED; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP; VANCOMYCIN;

BACTERIA (MICROORGANISMS);

EID: 12444269140     PISSN: 14394227     EISSN: None     Source Type: Journal    
DOI: 10.1002/cbic.200300619     Document Type: Article

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