Inhibition of a novel specific neuroglial integrin signaling pathway increases STAT3-mediated CNTF expression

Cell Communication and Signaling

Volumn 11, Issue 1, 2013, Pages

  Keasey, Matthew P ^a   Kang, Seong Su ^a   Lovins, Chiharu ^a   Hagg, Theo ^a  

^a University of Louisville School of Medicine   (United States)

Author keywords

Astrocyte; Ciliary neurotrophic factor; Focal adhesion kinase; Integrin; Intercellular communication; Mice; Neurogenesis; Neuron; Pharmacological; Transcriptional gene regulation

Indexed keywords

ALPHAVBETA5 INTEGRIN; CELL SURFACE PROTEIN; CILIARY NEUROTROPHIC FACTOR; COLLAGEN; FIBRINOGEN; FIBRONECTIN; FOCAL ADHESION KINASE; FOCAL ADHESION KINASE INHIBITOR; INTEGRIN; LAMININ; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN THY1; SERINE; STAT3 PROTEIN; STRESS ACTIVATED PROTEIN KINASE; THROMBOSPONDIN; TYROSINE; UNCLASSIFIED DRUG; VITRONECTIN; 6-(4-(3-(METHYLSULFONYL)BENZYLAMINO)-5-(TRIFLUOROMETHYL)PYRIMIDIN-2-YLAMINO)-3,4-DIHYDROQUINOLIN-2(1H)-ONE; QUINOLONE DERIVATIVE; SULFONE; THY 1 ANTIGEN; VITRONECTIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; ASTROCYTOMA; CILIARY NEUROTROPHIC FACTOR GENE; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; GENE; GENE EXPRESSION REGULATION; GENE REPRESSION; GLIA CELL; GLIOMA CELL; INHIBITION KINETICS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEWBORN; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; RESIDUE ANALYSIS; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; ASTROCYTE; C57BL MOUSE; DRUG EFFECTS; GENETICS; GLIA; METABOLISM; NERVE CELL; PHOSPHORYLATION; RAT; TUMOR CELL LINE;

MUS;

ANIMALS; ANTIGENS, THY-1; ASTROCYTES; CELL LINE, TUMOR; CILIARY NEUROTROPHIC FACTOR; COCULTURE TECHNIQUES; FOCAL ADHESION PROTEIN-TYROSINE KINASES; MICE, INBRED C57BL; NEUROGENESIS; NEUROGLIA; NEURONS; PHOSPHORYLATION; QUINOLONES; RATS; RECEPTORS, VITRONECTIN; SERINE; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; SULFONES; TYROSINE;

EID: 84877877778     PISSN: None     EISSN: 1478811X     Source Type: Journal    
DOI: 10.1186/1478-811X-11-35     Document Type: Article

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