β1 integrin/FAK/ERK signalling pathway is essential for human fetal islet cell differentiation and survival

Journal of Pathology

Volumn 219, Issue 2, 2009, Pages 182-192

  Saleem, Saira ^a   Li, Jinming ^a   Yee, Siu Pok ^a   Fellows, George F ^a   Goodyer, Cynthia G ^b   Wang, Rennian ^a,c  

^a UNIVERSITY OF WESTERN ONTARIO   (Canada)

^b MCGILL UNIVERSITY   (Canada)

^c Victoria Research Laboratories   (Canada)

Author keywords

1 integrin functional blockade; Collagen I matrix; ERK1 2; FAK; Focal adhesion; Human fetal islet epithelial cell clusters

Indexed keywords

BETA1 INTEGRIN; BLOCKING ANTIBODY; CASPASE 3; CASPASE 9; CELL MARKER; COLLAGEN TYPE 1; FOCAL ADHESION KINASE; GLUCAGON; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR PDX 1; FOCAL ADHESION KINASE 1; PTK2 PROTEIN, HUMAN;

ARTICLE; CELL ACTIVATION; CELL ADHESION; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL SURVIVAL; CELL TYPE; CONTROLLED STUDY; ENDOCRINE CELL; FETUS; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PANCREAS ISLET CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REDUCTION; SIGNAL TRANSDUCTION; CYTOLOGY; EPITHELIUM CELL; FETUS DEVELOPMENT; GENE SILENCING; GENETICS; PANCREAS ISLET; PHYSIOLOGY; PRENATAL DEVELOPMENT;

ANTIGENS, CD29; CELL ADHESION; CELL DIFFERENTIATION; CELL SURVIVAL; CELLS, CULTURED; EPITHELIAL CELLS; FETAL DEVELOPMENT; FOCAL ADHESION KINASE 1; GENE KNOCKDOWN TECHNIQUES; HUMANS; ISLETS OF LANGERHANS; MAP KINASE SIGNALING SYSTEM;

EID: 70349150179     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.2577     Document Type: Article

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