The Co-Repressor SMRT Delays DNA Damage-Induced Caspase Activation by Repressing Pro-Apoptotic Genes and Modulating the Dynamics of Checkpoint Kinase 2 Activation

PLoS ONE

Volumn 8, Issue 5, 2013, Pages

  Scafoglio, Claudio ^a,b   Smolka, Marcus ^c,d   Zhou, Huilin ^c   Perissi, Valentina ^a,e   Rosenfeld, Michael G ^a,c  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d School of Integrative Plant Sciences   (United States)

^e BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CHECKPOINT KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAX PROTEIN; NUCLEAR RECEPTOR COREPRESSOR; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN FOS; SILENCING MEDIATOR OF RETINOID AND THYROID HORMONE RECEPTOR; SMAD7 PROTEIN; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; WIP1 PROTEIN; PROTEIN PHOSPHATASE 2C;

APOPTOSIS; ARTICLE; BCL2L11 GENE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; FOS GENE; GENE REPRESSION; HELA CELL; MAX GENE; OSTEOSARCOMA CELL; PPM1D GENE; PROMOTER REGION; PROTEIN DEPHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; SMAD7 GENE; SRPK2 GENE; TRANSCRIPTION REGULATION; CHROMATIN IMMUNOPRECIPITATION; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; MICROARRAY ANALYSIS; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CHECKPOINT KINASE 2; CHROMATIN IMMUNOPRECIPITATION; DNA DAMAGE; ENZYME ACTIVATION; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION REGULATION; HUMANS; MICROARRAY ANALYSIS; NUCLEAR RECEPTOR CO-REPRESSOR 2; PHOSPHOPROTEIN PHOSPHATASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 84877853877     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0059986     Document Type: Article

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