-
1
-
-
27244452986
-
Genetics of myeloid malignancies: Pathogenetic and clinical implications
-
Frohling S, Scholl C, Gilliland DG, Levine RL. Genetics of myeloid malignancies: pathogenetic and clinical implications. J Clin Oncol 2005; 23: 6285-6295.
-
(2005)
J Clin Oncol
, vol.23
, pp. 6285-6295
-
-
Frohling, S.1
Scholl, C.2
Gilliland, D.G.3
Levine, R.L.4
-
2
-
-
81955165195
-
Incidence of haematological malignancy by sub-type: A report from the Haematological Malignancy Research Network
-
Smith A, Howell D, Patmore R, Jack A, Roman E. Incidence of haematological malignancy by sub-type: a report from the Haematological Malignancy Research Network. Br J Cancer 2011; 105: 1684-1692.
-
(2011)
Br J Cancer
, vol.105
, pp. 1684-1692
-
-
Smith, A.1
Howell, D.2
Patmore, R.3
Jack, A.4
Roman, E.5
-
3
-
-
33751267902
-
Acute myeloid leukaemia
-
Estey E, Döhner H. Acute myeloid leukaemia. The Lancet 2006; 368: 1894-1907.
-
(2006)
The Lancet
, vol.368
, pp. 1894-1907
-
-
Estey, E.1
Döhner, H.2
-
4
-
-
33846230449
-
Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: Are we ready for a prognostically prioritized molecular classification
-
Mrózek K, Marcucci G, Paschka P, Whitman SP, Bloomfield CD. Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification? Blood 2007; 109: 431-448.
-
(2007)
Blood
, vol.109
, pp. 431-448
-
-
Mrózek, K.1
Marcucci, G.2
Paschka, P.3
Whitman, S.P.4
Bloomfield, C.D.5
-
5
-
-
46849122024
-
Molecular characterization of acute myeloid leukemia
-
Dohner K, Dohner H. Molecular characterization of acute myeloid leukemia. Haematologica 2008; 93: 976-982.
-
(2008)
Haematologica
, vol.93
, pp. 976-982
-
-
Dohner, K.1
Dohner, H.2
-
6
-
-
44049086446
-
Cooperating gene mutations in acute myeloid leukemia: A review of the literature
-
Renneville A, Roumier C, Biggio V, Nibourel O, Boissel N, Fenaux P et al. Cooperating gene mutations in acute myeloid leukemia: a review of the literature. Leukemia 2008; 22: 915-931.
-
(2008)
Leukemia
, vol.22
, pp. 915-931
-
-
Renneville, A.1
Roumier, C.2
Biggio, V.3
Nibourel, O.4
Boissel, N.5
Fenaux, P.6
-
7
-
-
77958531206
-
Acute myeloid leukemia diagnosis in the 21st century
-
Betz BL, Hess JL. Acute myeloid leukemia diagnosis in the 21st century. Arch Pathol Lab Med 2010; 134: 1427-1433.
-
(2010)
Arch Pathol Lab Med
, vol.134
, pp. 1427-1433
-
-
Betz, B.L.1
Hess, J.L.2
-
8
-
-
13444267968
-
ParaHox, ProtoHox: Facts and guesses
-
Hox Garcia-FernandezJ. ParaHox, ProtoHox: facts and guesses. Heredity 2004; 94: 145-152.
-
(2004)
Heredity
, vol.94
, pp. 145-152
-
-
Hox Garcia-Fernandez, J.1
-
9
-
-
77951605788
-
The Hox genes and their roles in oncogenesis
-
Shah N, Sukumar S. The Hox genes and their roles in oncogenesis. Nat Rev Cancer 2010; 10: 361-371.
-
(2010)
Nat Rev Cancer
, vol.10
, pp. 361-371
-
-
Shah, N.1
Sukumar, S.2
-
11
-
-
0032573579
-
Zebrafish hox clusters and vertebrate genome evolution
-
Amores A, Force A, Yan YL, Joly L, Amemiya C, Fritz A et al. Zebrafish hox clusters and vertebrate genome evolution. Science 1998; 282: 1711-1714.
-
(1998)
Science
, vol.282
, pp. 1711-1714
-
-
Amores, A.1
Force, A.2
Yan, Y.L.3
Joly, L.4
Amemiya, C.5
Fritz, A.6
-
12
-
-
34147167683
-
HOX deregulation in acute myeloid leukemia
-
Rice KL, Licht JD. HOX deregulation in acute myeloid leukemia. J Clin Invest 2007; 117: 865-868.
-
(2007)
J Clin Invest
, vol.117
, pp. 865-868
-
-
Rice, K.L.1
Licht, J.D.2
-
13
-
-
79251609962
-
Epigenetic regulations in hematopoietic Hox code
-
He H, Hua X, Yan J. Epigenetic regulations in hematopoietic Hox code. Oncogene 2011; 30: 379-388.
-
(2011)
Oncogene
, vol.30
, pp. 379-388
-
-
He, H.1
Hua, X.2
Yan, J.3
-
14
-
-
0028929415
-
A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development
-
Knittel T, Kessel M, Kim MH, Gruss P. A conserved enhancer of the human and murine Hoxa-7 gene specifies the anterior boundary of expression during embryonal development. Development 1995; 121: 1077-1088.
-
(1995)
Development
, vol.121
, pp. 1077-1088
-
-
Knittel, T.1
Kessel, M.2
Kim, M.H.3
Gruss, P.4
-
15
-
-
0029008293
-
Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif
-
Phelan M, Rambaldi I, Featherstone M. Cooperative interactions between HOX and PBX proteins mediated by a conserved peptide motif. Mol Cell Biol 1995; 15: 3989-3997.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 3989-3997
-
-
Phelan, M.1
Rambaldi, I.2
Featherstone, M.3
-
16
-
-
33644976371
-
Hox cofactors in vertebrate development
-
Moens CB, Selleri L. Hox cofactors in vertebrate development. Dev Biol 2006; 291: 193-206.
-
(2006)
Dev Biol
, vol.291
, pp. 193-206
-
-
Moens, C.B.1
Selleri, L.2
-
18
-
-
0034747741
-
Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia
-
Thorsteinsdottir U, Kroon E, Jerome L, Blasi F, Sauvageau G. Defining roles for HOX and MEIS1 genes in induction of acute myeloid leukemia. Mol Cell Biol 2001; 21: 224-234.
-
(2001)
Mol Cell Biol
, vol.21
, pp. 224-234
-
-
Thorsteinsdottir, U.1
Kroon, E.2
Jerome, L.3
Blasi, F.4
Sauvageau, G.5
-
19
-
-
0035437164
-
The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver
-
Dimartino JF, Selleri L, Traver D, Firpo MT, Rhee J, Warnke R et al. The Hox cofactor and proto-oncogene Pbx1 is required for maintenance of definitive hematopoiesis in the fetal liver. Blood 2001; 98: 618-626.
-
(2001)
Blood
, vol.98
, pp. 618-626
-
-
Dimartino, J.F.1
Selleri, L.2
Traver, D.3
Firpo, M.T.4
Rhee, J.5
Warnke, R.6
-
20
-
-
10744229578
-
Hematopoietic, angiogenic and eye defects in Meis1 mutant animals
-
Hisa T, Spence SE, Rachel RA, Fujita M, Nakamura T, Ward JM et al. Hematopoietic, angiogenic and eye defects in Meis1 mutant animals. EMBO J 2004; 23: 450-459.
-
(2004)
EMBO J
, vol.23
, pp. 450-459
-
-
Hisa, T.1
Spence, S.E.2
Rachel, R.A.3
Fujita, M.4
Nakamura, T.5
Ward, J.M.6
-
21
-
-
77951204547
-
The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis
-
Pillay LM, Forrester AM, Erickson T, Berman JN, Waskiewicz AJ. The Hox cofactors Meis1 and Pbx act upstream of gata1 to regulate primitive hematopoiesis. Dev Biol 2010; 340: 306-317.
-
(2010)
Dev Biol
, vol.340
, pp. 306-317
-
-
Pillay, L.M.1
Forrester, A.M.2
Erickson, T.3
Berman, J.N.4
Waskiewicz, A.J.5
-
22
-
-
0029865897
-
Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA
-
Shen WF, Chang CP, Rozenfeld S, Sauvageau G, Humphries RK, Lu M et al. Hox homeodomain proteins exhibit selective complex stabilities with Pbx and DNA. Nucleic Acids Res 1996; 24: 898-906.
-
(1996)
Nucleic Acids Res
, vol.24
, pp. 898-906
-
-
Shen, W.F.1
Chang, C.P.2
Rozenfeld, S.3
Sauvageau, G.4
Humphries, R.K.5
Lu, M.6
-
23
-
-
0030848853
-
AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins
-
Shen W, Montgomery J, Rozenfeld S, Moskow J, Lawrence H, Buchberg AC et al. AbdB-like Hox proteins stabilize DNA binding by the Meis1 homeodomain proteins. Mol Cell Biol 1997; 17: 6448-6458.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 6448-6458
-
-
Shen, W.1
Montgomery, J.2
Rozenfeld, S.3
Moskow, J.4
Lawrence, H.5
Buchberg, A.C.6
-
24
-
-
0028131836
-
Key functional role and lineage-specific expression of selected HOXB genes in purified hematopoietic progenitor differentiation
-
Giampaolo A, Sterpetti P, Bulgarini D, Samoggia P, Pelosi E, Valtieri M et al. Key functional role and lineage-specific expression of selected HOXB genes in purified hematopoietic progenitor differentiation. Blood 1994; 84: 3637-3647.
-
(1994)
Blood
, vol.84
, pp. 3637-3647
-
-
Giampaolo, A.1
Sterpetti, P.2
Bulgarini, D.3
Samoggia, P.4
Pelosi, E.5
Valtieri, M.6
-
25
-
-
0032981197
-
Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells
-
Kawagoe H, Humphries RK, Blair A, Sutherland HJ, Hogge DE. Expression of HOX genes, HOX cofactors, and MLL in phenotypically and functionally defined subpopulations of leukemic and normal human hematopoietic cells. Leukemia 1999; 13: 687-698.
-
(1999)
Leukemia
, vol.13
, pp. 687-698
-
-
Kawagoe, H.1
Humphries, R.K.2
Blair, A.3
Sutherland, H.J.4
Hogge, D.E.5
-
26
-
-
0036142691
-
Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny
-
Pineault N, Helgason CD, Lawrence HJ, Humphries RK. Differential expression of Hox, Meis1, and Pbx1 genes in primitive cells throughout murine hematopoietic ontogeny. Exp Hematol 2002; 30: 49-57.
-
(2002)
Exp Hematol
, vol.30
, pp. 49-57
-
-
Pineault, N.1
Helgason, C.D.2
Lawrence, H.J.3
Humphries, R.K.4
-
27
-
-
13644265950
-
The pathophysiology of HOX genes and their role in cancer
-
Grier DG, Thompson A, Kwasniewska A, Mcgonigle GJ, Halliday HL, Lappin TR. The pathophysiology of HOX genes and their role in cancer. J Pathol 2005; 205: 154-171.
-
(2005)
J Pathol
, vol.205
, pp. 154-171
-
-
Grier, D.G.1
Thompson, A.2
Kwasniewska, A.3
McGonigle, G.J.4
Halliday, H.L.5
Lappin, T.R.6
-
28
-
-
0028079924
-
Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells
-
Sauvageau G, Lansdorp PM, Eaves CJ, Hogge DE, Dragowska WH, Reid DS et al. Differential expression of homeobox genes in functionally distinct CD34+ subpopulations of human bone marrow cells. Proc Natl Acad Sci USA 1994; 91: 12223-12227.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 12223-12227
-
-
Sauvageau, G.1
Lansdorp, P.M.2
Eaves, C.J.3
Hogge, D.E.4
Dragowska, W.H.5
Reid, D.S.6
-
29
-
-
0038040548
-
Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: Implications for human T-cell development
-
Taghon T, Thys K, De Smedt M, Weerkamp F, Staal FJT, Plum J et al. Homeobox gene expression profile in human hematopoietic multipotent stem cells and T-cell progenitors: implications for human T-cell development. Leukemia 2003; 17: 1157-1163.
-
(2003)
Leukemia
, vol.17
, pp. 1157-1163
-
-
Taghon, T.1
Thys, K.2
De Smedt, M.3
Weerkamp, F.4
Staal, F.J.T.5
Plum, J.6
-
30
-
-
0033566308
-
Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors
-
Crooks GM, Fuller J, Petersen D, Izadi P, Malik P, Pattengale PK et al. Constitutive HOXA5 expression inhibits erythropoiesis and increases myelopoiesis from human hematopoietic progenitors. Blood 1999; 94: 519-528.
-
(1999)
Blood
, vol.94
, pp. 519-528
-
-
Crooks, G.M.1
Fuller, J.2
Petersen, D.3
Izadi, P.4
Malik, P.5
Pattengale, P.K.6
-
31
-
-
0033562799
-
Characterization of HOX gene expression during myelopoiesis: Role of HOX A5 in lineage commitment and maturation
-
Fuller JF, Mcadara J, Yaron Y, Sakaguchi M, Fraser JK, Gasson JC. Characterization of HOX gene expression during myelopoiesis: role of HOX A5 in lineage commitment and maturation. Blood 1999; 93: 3391-3400.
-
(1999)
Blood
, vol.93
, pp. 3391-3400
-
-
Fuller, J.F.1
McAdara, J.2
Yaron, Y.3
Sakaguchi, M.4
Fraser, J.K.5
Gasson, J.C.6
-
32
-
-
1842579481
-
Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9
-
So CW, Karsunky H, Wong P, Weissman IL, Cleary ML. Leukemic transformation of hematopoietic progenitors by MLL-GAS7 in the absence of Hoxa7 or Hoxa9. Blood 2004; 103: 3192-3199.
-
(2004)
Blood
, vol.103
, pp. 3192-3199
-
-
So, C.W.1
Karsunky, H.2
Wong, P.3
Weissman, I.L.4
Cleary, M.L.5
-
33
-
-
0032126633
-
Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b
-
Kroon E, Krosl J, Thorsteinsdottir U, Baban S, Buchberg AM, Sauvageau G. Hoxa9 transforms primary bone marrow cells through specific collaboration with Meis1a but not Pbx1b. EMBO J 1998; 17: 3714-3725.
-
(1998)
EMBO J
, vol.17
, pp. 3714-3725
-
-
Kroon, E.1
Krosl, J.2
Thorsteinsdottir, U.3
Baban, S.4
Buchberg, A.M.5
Sauvageau, G.6
-
34
-
-
0036090290
-
Overexpression of the myeloid leukemia-associatedHoxa9 gene in bone marrow cells induces stem cell expansion
-
Thorsteinsdottir U, Mamo A, Kroon E, Jerome L, Bijl J, Lawrence HJ et al. Overexpression of the myeloid leukemia-associatedHoxa9 gene in bone marrow cells induces stem cell expansion. Blood 2002; 99: 121-129.
-
(2002)
Blood
, vol.99
, pp. 121-129
-
-
Thorsteinsdottir, U.1
Mamo, A.2
Kroon, E.3
Jerome, L.4
Bijl, J.5
Lawrence, H.J.6
-
35
-
-
34548180591
-
Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects
-
Magnusson M, Brun ACM, Lawrence HJ, Karlsson S. Hoxa9/hoxb3/hoxb4 compound null mice display severe hematopoietic defects. Exp Hematol 2007a; 35: 1421-1428.
-
(2007)
Exp Hematol
, vol.35
, pp. 1421-1428
-
-
Magnusson, M.1
Brun, A.C.M.2
Lawrence, H.J.3
Karlsson, S.4
-
36
-
-
0035871680
-
Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo
-
Buske C, Feuring-Buske M, Antonchuk J, Rosten P, Hogge DE, Eaves CJ et al. Overexpression of HOXA10 perturbs human lymphomyelopoiesis in vitro and in vivo. Blood 2001; 97: 2286-2292.
-
(2001)
Blood
, vol.97
, pp. 2286-2292
-
-
Buske, C.1
Feuring-Buske, M.2
Antonchuk, J.3
Rosten, P.4
Hogge, D.E.5
Eaves, C.J.6
-
37
-
-
0030891058
-
Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation
-
Sauvageau G, Thorsteinsdottir U, Hough MR, Hugo P, Lawrence HJ, Largman C et al. Overexpression of HOXB3 in hematopoietic cells causes defective lymphoid development and progressive myeloproliferation. Immunity 1997; 6: 13-22.
-
(1997)
Immunity
, vol.6
, pp. 13-22
-
-
Sauvageau, G.1
Thorsteinsdottir, U.2
Hough, M.R.3
Hugo, P.4
Lawrence, H.J.5
Largman, C.6
-
38
-
-
33847069599
-
Hoxb3 deficiency impairs B lymphopoiesis in mouse bone marrow
-
Ko KH, Kwan Lam QL, Zhang M, Yen Wong CK, Chun LOCK, Kahmeyer-Gabbe M et al. Hoxb3 deficiency impairs B lymphopoiesis in mouse bone marrow. Exp Hematol 2007; 35: 465-475.
-
(2007)
Exp Hematol
, vol.35
, pp. 465-475
-
-
Ko, K.H.1
Kwan Lam, Q.L.2
Zhang, M.3
Yen Wong, C.K.4
Chun, L.O.C.K.5
Kahmeyer-Gabbe, M.6
-
39
-
-
0029091845
-
Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo
-
Sauvageau G, Thorsteinsdottir U, Eaves CJ, Lawrence HJ, Largman C, Lansdorp PM et al. Overexpression of HOXB4 in hematopoietic cells causes the selective expansion of more primitive populations in vitro and in vivo. Genes Dev 1995; 9: 1753-1765.
-
(1995)
Genes Dev
, vol.9
, pp. 1753-1765
-
-
Sauvageau, G.1
Thorsteinsdottir, U.2
Eaves, C.J.3
Lawrence, H.J.4
Largman, C.5
Lansdorp, P.M.6
-
40
-
-
0345708270
-
Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein
-
Amsellem S, Pflumio F, Bardinet D, Izac B, Charneau P, Romeo PH et al. Ex vivo expansion of human hematopoietic stem cells by direct delivery of the HOXB4 homeoprotein. Nat Med 2003; 9: 1423-1427.
-
(2003)
Nat Med
, vol.9
, pp. 1423-1427
-
-
Amsellem, S.1
Pflumio, F.2
Bardinet, D.3
Izac, B.4
Charneau, P.5
Romeo, P.H.6
-
41
-
-
2542467750
-
Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells
-
Brun ACM, Björnsson JM, Magnusson M, Larsson N, Leveén P, Ehinger M et al. Hoxb4-deficient mice undergo normal hematopoietic development but exhibit a mild proliferation defect in hematopoietic stem cells. Blood 2004; 103: 4126-4133.
-
(2004)
Blood
, vol.103
, pp. 4126-4133
-
-
Brun, A.C.M.1
Björnsson, J.M.2
Magnusson, M.3
Larsson, N.4
Leveén, P.5
Ehinger, M.6
-
42
-
-
33745605199
-
Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells
-
Bijl J, Thompson A, Ramirez-Solis R, Krosl J, Grier DG, Lawrence HJ et al. Analysis of HSC activity and compensatory Hox gene expression profile in Hoxb cluster mutant fetal liver cells. Blood 2006; 108: 116-122.
-
(2006)
Blood
, vol.108
, pp. 116-122
-
-
Bijl, J.1
Thompson, A.2
Ramirez-Solis, R.3
Krosl, J.4
Grier, D.G.5
Lawrence, H.J.6
-
43
-
-
0038246245
-
Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4
-
Bjornsson JM, Larsson N, Brun ACM, Magnusson M, Andersson E, Lundstrom P et al. Reduced proliferative capacity of hematopoietic stem cells deficient in Hoxb3 and Hoxb4. Mol Cell Biol 2003; 23: 3872-3883.
-
(2003)
Mol Cell Biol
, vol.23
, pp. 3872-3883
-
-
Bjornsson, J.M.1
Larsson, N.2
Brun, A.C.M.3
Magnusson, M.4
Andersson, E.5
Lundstrom, P.6
-
44
-
-
13544262343
-
HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo
-
Fischbach NA, Rozenfeld S, Shen W, Fong S, Chrobak D, Ginzinger D et al. HOXB6 overexpression in murine bone marrow immortalizes a myelomonocytic precursor in vitro and causes hematopoietic stem cell expansion and acute myeloid leukemia in vivo. Blood 2005; 105: 1456-1466.
-
(2005)
Blood
, vol.105
, pp. 1456-1466
-
-
Fischbach, N.A.1
Rozenfeld, S.2
Shen, W.3
Fong, S.4
Chrobak, D.5
Ginzinger, D.6
-
45
-
-
0033824190
-
Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte progenitors
-
Kappen C. Disruption of the homeobox gene Hoxb-6 in mice results in increased numbers of early erythrocyte progenitors. Am J Hematol 2000; 65: 111-118.
-
(2000)
Am J Hematol
, vol.65
, pp. 111-118
-
-
Kappen, C.1
-
46
-
-
0027538180
-
A homeobox gene of the antennapedia class is required for human adult erythropoiesis
-
Takeshita K, Bollekens JA, Hijiya N, Ratajczak M, Ruddle FH, Gewirtz AM. A homeobox gene of the antennapedia class is required for human adult erythropoiesis. Proc Natl Acad Sci USA 1993; 90: 3535-3538.
-
(1993)
Proc Natl Acad Sci USA
, vol.90
, pp. 3535-3538
-
-
Takeshita, K.1
Bollekens, J.A.2
Hijiya, N.3
Ratajczak, M.4
Ruddle, F.H.5
Gewirtz, A.M.6
-
47
-
-
0034104768
-
The retroviral transduction of HOXC4 into human CD34+ cells induces an in vitro expansion of clonogenic and early progenitors
-
Daga A, Podesta M, Capra MC, Piaggio G, Frassoni F, Corte G. The retroviral transduction of HOXC4 into human CD34+ cells induces an in vitro expansion of clonogenic and early progenitors. Exp Hematol 2000; 28: 569-574.
-
(2000)
Exp Hematol
, vol.28
, pp. 569-574
-
-
Daga, A.1
Podesta, M.2
Capra, M.C.3
Piaggio, G.4
Frassoni, F.5
Corte, G.6
-
48
-
-
0033080853
-
Hematopoietic progenitor cell abnormalities in Hoxc-8 null mutant mice
-
Shimamoto T, Tang Y, Naot Y, Nardi M, Brulet P, Bieberich CJ et al. Hematopoietic progenitor cell abnormalities in Hoxc-8 null mutant mice. J Exp Zool 1999; 283: 186-193.
-
(1999)
J Exp Zool
, vol.283
, pp. 186-193
-
-
Shimamoto, T.1
Tang, Y.2
Naot, Y.3
Nardi, M.4
Brulet, P.5
Bieberich, C.J.6
-
49
-
-
0037396675
-
The competitive nature of HOXB4-transduced HSC is limited by PBX1: The generation of ultra-competitive stem cells retaining full differentiation potential
-
Krosl J, Beslu N, Mayotte N, Humphries RK, Sauvageau G. The competitive nature of HOXB4-transduced HSC is limited by PBX1: the generation of ultra-competitive stem cells retaining full differentiation potential. Immunity 2003; 18: 561-571.
-
(2003)
Immunity
, vol.18
, pp. 561-571
-
-
Krosl, J.1
Beslu, N.2
Mayotte, N.3
Humphries, R.K.4
Sauvageau, G.5
-
50
-
-
34247376989
-
Sustained in vitro trigger of self-renewal divisions in Hoxb4(hi)Pbx1(lo) hematopoietic stem cells
-
Cellot S, Krosl J, Chagraoui J, Meloche S, Humphries RK, Sauvageau G. Sustained in vitro trigger of self-renewal divisions in Hoxb4(hi)Pbx1(lo) hematopoietic stem cells. Exp Hematol 2007; 35: 802-816.
-
(2007)
Exp Hematol
, vol.35
, pp. 802-816
-
-
Cellot, S.1
Krosl, J.2
Chagraoui, J.3
Meloche, S.4
Humphries, R.K.5
Sauvageau, G.6
-
51
-
-
0035073765
-
Polycomb group proteins and heritable silencing of Drosophila Hox genes
-
Beuchle D, Struhl G, Muller J. Polycomb group proteins and heritable silencing of Drosophila Hox genes. Development 2001; 128: 993-1004.
-
(2001)
Development
, vol.128
, pp. 993-1004
-
-
Beuchle, D.1
Struhl, G.2
Muller, J.3
-
52
-
-
9244257908
-
An Mll-dependent Hox program drives hematopoietic progenitor expansion
-
Ernst P, Mabon M, Davidson AJ, Zon LI, Korsmeyer SJ. An Mll-dependent Hox program drives hematopoietic progenitor expansion. Curr Biol 2004; 14: 2063-2069.
-
(2004)
Curr Biol
, vol.14
, pp. 2063-2069
-
-
Ernst, P.1
Mabon, M.2
Davidson, A.J.3
Zon, L.I.4
Korsmeyer, S.J.5
-
53
-
-
34548462072
-
Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors
-
Jude CD, Climer L, Xu D, Artinger E, Fisher JK, Ernst P. Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors. Cell stem cell 2007; 1: 324-337.
-
(2007)
Cell Stem Cell
, vol.1
, pp. 324-337
-
-
Jude, C.D.1
Climer, L.2
Xu, D.3
Artinger, E.4
Fisher, J.K.5
Ernst, P.6
-
54
-
-
33646913849
-
The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis
-
Davidson AJ, Zon LI. The caudal-related homeobox genes cdx1a and cdx4 act redundantly to regulate hox gene expression and the formation of putative hematopoietic stem cells during zebrafish embryogenesis. Dev Biol 2006; 292: 506-518.
-
(2006)
Dev Biol
, vol.292
, pp. 506-518
-
-
Davidson, A.J.1
Zon, L.I.2
-
55
-
-
45549103234
-
Cdx gene deficiency compromises embryonic hematopoiesis in the mouse
-
Wang Y, Yabuuchi A, Mckinney-Freeman S, Ducharme DMK, Ray MK, Chawengsaksophak K et al. Cdx gene deficiency compromises embryonic hematopoiesis in the mouse. Proc Natl Acad Sci USA 2008; 105: 7756-7761.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 7756-7761
-
-
Wang, Y.1
Yabuuchi, A.2
McKinney-Freeman, S.3
Ducharme, D.M.K.4
Ray, M.K.5
Chawengsaksophak, K.6
-
56
-
-
77957811310
-
Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis
-
Koo S, Huntly BJ, Wang Y, Chen J, Brumme K, Ball B et al. Cdx4 is dispensable for murine adult hematopoietic stem cells but promotes MLL-AF9-mediated leukemogenesis. Haematologica 2010; 95: 1642-1650.
-
(2010)
Haematologica
, vol.95
, pp. 1642-1650
-
-
Koo, S.1
Huntly, B.J.2
Wang, Y.3
Chen, J.4
Brumme, K.5
Ball, B.6
-
57
-
-
34147107042
-
The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis
-
Scholl C, Bansal D, Dohner K, Eiwen K, Huntly BJP, Lee BH et al. The homeobox gene CDX2 is aberrantly expressed in most cases of acute myeloid leukemia and promotes leukemogenesis. J Clin Invest 2007; 117: 1037-1048.
-
(2007)
J Clin Invest
, vol.117
, pp. 1037-1048
-
-
Scholl, C.1
Bansal, D.2
Dohner, K.3
Eiwen, K.4
Huntly, B.J.P.5
Lee, B.H.6
-
58
-
-
38049141542
-
Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia
-
Rawat VPS, Thoene S, Naidu VM, Arseni N, Heilmeier B, Metzeler K et al. Overexpression of CDX2 perturbs HOX gene expression in murine progenitors depending on its N-terminal domain and is closely correlated with deregulated HOX gene expression in human acute myeloid leukemia. Blood 2008; 111: 309-319.
-
(2008)
Blood
, vol.111
, pp. 309-319
-
-
Rawat, V.P.S.1
Thoene, S.2
Naidu, V.M.3
Arseni, N.4
Heilmeier, B.5
Metzeler, K.6
-
59
-
-
65449122002
-
Aberrant expression of the homeobox gene CDX2 in pediatric acute lymphoblastic leukemia
-
Riedt T, Ebinger M, Salih HR, Tomiuk J, Handgretinger R, Kanz L et al. Aberrant expression of the homeobox gene CDX2 in pediatric acute lymphoblastic leukemia. Blood 2009; 113: 4049-4051.
-
(2009)
Blood
, vol.113
, pp. 4049-4051
-
-
Riedt, T.1
Ebinger, M.2
Salih, H.R.3
Tomiuk, J.4
Handgretinger, R.5
Kanz, L.6
-
60
-
-
64049095814
-
HOXA9 is required for survival in human MLL-rearranged acute leukemias
-
Faber J, Krivtsov AV, Stubbs MC, Wright R, Davis TN, Van Den Heuvel-Eibrink M et al. HOXA9 is required for survival in human MLL-rearranged acute leukemias. Blood 2009; 113: 2375-2385.
-
(2009)
Blood
, vol.113
, pp. 2375-2385
-
-
Faber, J.1
Krivtsov, A.V.2
Stubbs, M.C.3
Wright, R.4
Davis, T.N.5
Van Den Heuvel-Eibrink, M.6
-
61
-
-
34249747880
-
Evidence that the Pim1 kinase gene is a direct target of HOXA9
-
Hu YL, PasseguéE, Fong S, Largman C, Lawrence HJ. Evidence that the Pim1 kinase gene is a direct target of HOXA9. Blood 2007; 109: 4732-4738.
-
(2007)
Blood
, vol.109
, pp. 4732-4738
-
-
Hu, Y.L.1
Passegué, E.2
Fong, S.3
Largman, C.4
Lawrence, H.J.5
-
62
-
-
77953583254
-
Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines
-
Nagel S, Venturini L, Marquez V, Meyer C, Kaufmann M, Scherr M et al. Polycomb repressor complex 2 regulates HOXA9 and HOXA10, activating ID2 in NK/T-cell lines. Mol Cancer 2010; 9: 151.
-
(2010)
Mol Cancer
, vol.9
, pp. 151
-
-
Nagel, S.1
Venturini, L.2
Marquez, V.3
Meyer, C.4
Kaufmann, M.5
Scherr, M.6
-
63
-
-
16844370003
-
HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation
-
Bei L, Lu Y, Eklund EA. HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation. J Biol Chem 2005; 280: 12359-12370.
-
(2005)
J Biol Chem
, vol.280
, pp. 12359-12370
-
-
Bei, L.1
Lu, Y.2
Eklund, E.A.3
-
64
-
-
78650671103
-
Hoxa9 regulates Flt3 in lymphohematopoietic progenitors
-
Gwin K, Frank E, Bossou A, Medina KL. Hoxa9 Regulates Flt3 in Lymphohematopoietic Progenitors. J Immunol 2010; 185: 6572-6583.
-
(2010)
J Immunol
, vol.185
, pp. 6572-6583
-
-
Gwin, K.1
Frank, E.2
Bossou, A.3
Medina, K.L.4
-
65
-
-
70249100266
-
HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis
-
Hu YL, Fong S, Ferrell C, Largman C, Shen WF. HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis. Mol Cell Biol 2009; 29: 5181-5192.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 5181-5192
-
-
Hu, Y.L.1
Fong, S.2
Ferrell, C.3
Largman, C.4
Shen, W.F.5
-
66
-
-
84862966022
-
Identification and characterization of Hoxa9 binding sites in hematopoietic cells
-
Huang Y, Sitwala K, Bronstein J, Sanders D, Dandekar M, Collins C et al. Identification and characterization of Hoxa9 binding sites in hematopoietic cells. Blood 2012; 119: 388-398.
-
(2012)
Blood
, vol.119
, pp. 388-398
-
-
Huang, Y.1
Sitwala, K.2
Bronstein, J.3
Sanders, D.4
Dandekar, M.5
Collins, C.6
-
67
-
-
33745595058
-
C-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells
-
Hess JL, Bittner CB, Zeisig DT, Bach C, Fuchs U, Borkhardt A et al. c-Myb is an essential downstream target for homeobox-mediated transformation of hematopoietic cells. Blood 2006; 108: 297-304.
-
(2006)
Blood
, vol.108
, pp. 297-304
-
-
Hess, J.L.1
Bittner, C.B.2
Zeisig, D.T.3
Bach, C.4
Fuchs, U.5
Borkhardt, A.6
-
68
-
-
33746167484
-
NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells
-
Takeda A, Goolsby C, Yaseen NR. NUP98-HOXA9 induces long-term proliferation and blocks differentiation of primary human CD34+ hematopoietic cells. Cancer Res 2006; 66: 6628-6637.
-
(2006)
Cancer Res
, vol.66
, pp. 6628-6637
-
-
Takeda, A.1
Goolsby, C.2
Yaseen, N.R.3
-
69
-
-
34247378195
-
HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/ megakaryocyte development
-
Magnusson M, Brun ACM, Miyake N, Larsson J, Ehinger M, Bjornsson JM et al. HOXA10 is a critical regulator for hematopoietic stem cells and erythroid/ megakaryocyte development. Blood 2007; 109: 3687-3696.
-
(2007)
Blood
, vol.109
, pp. 3687-3696
-
-
Magnusson, M.1
Brun, A.C.M.2
Miyake, N.3
Larsson, J.4
Ehinger, M.5
Bjornsson, J.M.6
-
70
-
-
34447115694
-
Identification of a HoxA10 activation domain necessary for transcription of the gene encoding b3 integrin during myeloid differentiation
-
Bei L, Lu Y, Bellis SL, Zhou W, Horvath E, Eklund EA. Identification of a HoxA10 activation domain necessary for transcription of the gene encoding b3 integrin during myeloid differentiation. J Biol Chem 2007; 282: 16846-16859.
-
(2007)
J Biol Chem
, vol.282
, pp. 16846-16859
-
-
Bei, L.1
Lu, Y.2
Bellis, S.L.3
Zhou, W.4
Horvath, E.5
Eklund, E.A.6
-
71
-
-
34447512474
-
HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells
-
Wang H, Lu Y, Huang W, Papoutsakis ET, Fuhrken P, Eklund EA. HoxA10 activates transcription of the gene encoding mitogen-activated protein kinase phosphatase 2 (Mkp2) in myeloid cells. J Biol Chem 2007; 282: 16164-16176.
-
(2007)
J Biol Chem
, vol.282
, pp. 16164-16176
-
-
Wang, H.1
Lu, Y.2
Huang, W.3
Papoutsakis, E.T.4
Fuhrken, P.5
Eklund, E.A.6
-
72
-
-
79956300892
-
HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells
-
Bei L, Huang W, Wang H, Shah C, Horvath E, Eklund E. HoxA10 activates CDX4 transcription and Cdx4 activates HOXA10 transcription in myeloid cells. J Biol Chem 2011; 286: 19047-19064.
-
(2011)
J Biol Chem
, vol.286
, pp. 19047-19064
-
-
Bei, L.1
Huang, W.2
Wang, H.3
Shah, C.4
Horvath, E.5
Eklund, E.6
-
73
-
-
0034667988
-
P21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells
-
Bromleigh VC, Freedman LP. p21 is a transcriptional target of HOXA10 in differentiating myelomonocytic cells. Genes Dev 2000; 14: 2581-2586.
-
(2000)
Genes Dev
, vol.14
, pp. 2581-2586
-
-
Bromleigh, V.C.1
Freedman, L.P.2
-
74
-
-
0034733573
-
Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon g-induced differentiation of myeloid leukemia cell lines
-
Eklund EA, Jalava A, Kakar R. Tyrosine phosphorylation of HoxA10 decreases DNA binding and transcriptional repression during interferon g-induced differentiation of myeloid leukemia cell lines. J Biol Chem 2000; 275: 20117-20126.
-
(2000)
J Biol Chem
, vol.275
, pp. 20117-20126
-
-
Eklund, E.A.1
Jalava, A.2
Kakar, R.3
-
75
-
-
40749092795
-
Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes
-
Palmqvist L, Pineault N, Wasslavik C, Humphries RK. Candidate genes for expansion and transformation of hematopoietic stem cells by NUP98-HOX fusion genes. PLoS ONE 2007; 2: e768.
-
(2007)
PLoS ONE
, vol.2
-
-
Palmqvist, L.1
Pineault, N.2
Wasslavik, C.3
Humphries, R.K.4
-
76
-
-
77956269498
-
Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells
-
Lee HM, Zhang H, Schulz V, Tuck DP, Forget BG. Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells. Blood 2010; 116: 720-730.
-
(2010)
Blood
, vol.116
, pp. 720-730
-
-
Lee, H.M.1
Zhang, H.2
Schulz, V.3
Tuck, D.P.4
Forget, B.G.5
-
77
-
-
0035069929
-
Antisense knockout of HOXB4 blocks 1,25-dihydroxyvitamin D3 inhibition of c-myc expression
-
Pan Q, Simpson R. Antisense knockout of HOXB4 blocks 1,25- dihydroxyvitamin D3 inhibition of c-myc expression. J Endocrinol 2001; 169: 153-159.
-
(2001)
J Endocrinol
, vol.169
, pp. 153-159
-
-
Pan, Q.1
Simpson, R.2
-
78
-
-
2942558501
-
Roles for c-Myc in self-renewal of hematopoietic stem cells
-
Satoh Y, Matsumura I, Tanaka H, Ezoe S, Sugahara H, Mizuki M et al. Roles for c-Myc in self-renewal of hematopoietic stem cells. J Biol Chem 2004; 279: 24986-24993.
-
(2004)
J Biol Chem
, vol.279
, pp. 24986-24993
-
-
Satoh, Y.1
Matsumura, I.2
Tanaka, H.3
Ezoe, S.4
Sugahara, H.5
Mizuki, M.6
-
79
-
-
0034718780
-
AP-1 complex is effector of Hox-induced cellular proliferation and transformation
-
Krosl J, Sauvageau G. AP-1 complex is effector of Hox-induced cellular proliferation and transformation. Oncogene 2000; 19: 5134-5141.
-
(2000)
Oncogene
, vol.19
, pp. 5134-5141
-
-
Krosl, J.1
Sauvageau, G.2
-
80
-
-
0032185769
-
Pim-1 Kinase and p100 cooperate to enhance c-Myb activity
-
Leverson JD, Koskinen PJ, Orrico FC, Rainio EM, Jalkanen KJ, Dash AB et al. Pim-1 Kinase and p100 cooperate to enhance c-Myb activity. Mol Cell 1998; 2: 417-425.
-
(1998)
Mol Cell
, vol.2
, pp. 417-425
-
-
Leverson, J.D.1
Koskinen, P.J.2
Orrico, F.C.3
Rainio, E.M.4
Jalkanen, K.J.5
Dash, A.B.6
-
81
-
-
84861540139
-
HoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells
-
Shah CA, Bei L, Wang H, Platanias LC, Eklund EA. HoxA10 protein regulates transcription of gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells. J Biol Chem 2012; 287: 18230-18248.
-
(2012)
J Biol Chem
, vol.287
, pp. 18230-18248
-
-
Shah, C.A.1
Bei, L.2
Wang, H.3
Platanias, L.C.4
Eklund, E.A.5
-
82
-
-
78951489486
-
HoxA10 Regulates Transcription of the Gene Encoding Transforming Growth Factor b2 (TGFb2) in Myeloid Cells
-
Shah CA, Wang H, Bei L, Platanias LC, Eklund EA. HoxA10 Regulates Transcription of the Gene Encoding Transforming Growth Factor b2 (TGFb2) in Myeloid Cells. J Biol Chem 2011; 286: 3161-3176.
-
(2011)
J Biol Chem
, vol.286
, pp. 3161-3176
-
-
Shah, C.A.1
Wang, H.2
Bei, L.3
Platanias, L.C.4
Eklund, E.A.5
-
83
-
-
79954595962
-
Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells
-
Oshima M, Endoh M, Endo TA, Toyoda T, Nakajima-Takagi Y, Sugiyama F et al. Genome-wide analysis of target genes regulated by HoxB4 in hematopoietic stem and progenitor cells developing from embryonic stem cells. Blood 2011; 117: e142-e150.
-
(2011)
Blood
, vol.117
-
-
Oshima, M.1
Endoh, M.2
Endo, T.A.3
Toyoda, T.4
Nakajima-Takagi, Y.5
Sugiyama, F.6
-
84
-
-
84861053031
-
Dynamic HoxB4 regulatory network during embryonic stem cell differentiation to hematopoietic cells
-
Fan R, Bonde S, Gao P, Sotomayor B, Chen C, Mouw T et al. Dynamic HoxB4 regulatory network during embryonic stem cell differentiation to hematopoietic cells. Blood 2012; 119: e139-e147.
-
(2012)
Blood
, vol.119
-
-
Fan, R.1
Bonde, S.2
Gao, P.3
Sotomayor, B.4
Chen, C.5
Mouw, T.6
-
85
-
-
9044241254
-
Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia
-
Nakamura T, Largaespada DA, Lee MP, Johnson LA, Ohyashiki K, Toyama K et al. Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia. Nat Genet 1996; 12: 154-158.
-
(1996)
Nat Genet
, vol.12
, pp. 154-158
-
-
Nakamura, T.1
Largaespada, D.A.2
Lee, M.P.3
Johnson, L.A.4
Ohyashiki, K.5
Toyama, K.6
-
86
-
-
9044249724
-
The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP96 and class i homeoprotein HOXA9
-
Borrow J, Shearman AM, Stanton VP, Becher R, Collins T, Williams AJ et al. The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP96 and class I homeoprotein HOXA9. Nat Genet 1996; 12: 159-167.
-
(1996)
Nat Genet
, vol.12
, pp. 159-167
-
-
Borrow, J.1
Shearman, A.M.2
Stanton, V.P.3
Becher, R.4
Collins, T.5
Williams, A.J.6
-
87
-
-
0037082502
-
Single-translocation and double-chimeric transcripts: Detection of NUP98-HOXA9 in myeloid leukemias withHOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15)
-
Fujino T, Suzuki A, Ito Y, Ohyashiki K, Hatano Y, Miura I et al. Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias withHOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15). Blood 2002; 99: 1428-1433.
-
(2002)
Blood
, vol.99
, pp. 1428-1433
-
-
Fujino, T.1
Suzuki, A.2
Ito, Y.3
Ohyashiki, K.4
Hatano, Y.5
Miura, I.6
-
88
-
-
0036164903
-
T(7;11)(p15;p15) chronic myeloid leukaemia developed into blastic transformation showing a novel NUP98/HOXA11 fusion
-
Suzuki A, Ito Y, Sashida G, Honda S, Katagiri T, Fujino T et al. t(7;11)(p15;p15) chronic myeloid leukaemia developed into blastic transformation showing a novel NUP98/HOXA11 fusion. Br J Haematol 2002; 116: 170-172.
-
(2002)
Br J Haematol
, vol.116
, pp. 170-172
-
-
Suzuki, A.1
Ito, Y.2
Sashida, G.3
Honda, S.4
Katagiri, T.5
Fujino, T.6
-
89
-
-
0032190079
-
NUP98-HOXD13 gene fusion in therapy-related acute myelogenous leukemia
-
Raza-Egilmez SZ, Jani-Sait SN, Grossi M, Higgins MJ, Shows TB, Aplan PD. NUP98- HOXD13 gene fusion in therapy-related acute myelogenous leukemia. Cancer Res 1998; 58: 4269-4273.
-
(1998)
Cancer Res
, vol.58
, pp. 4269-4273
-
-
Raza-Egilmez, S.Z.1
Jani-Sait, S.N.2
Grossi, M.3
Higgins, M.J.4
Shows, T.B.5
Aplan, P.D.6
-
90
-
-
0036143026
-
The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15)
-
Taketani T, Taki T, Shibuya N, Ito E, Kitazawa J, Terui K et al. The HOXD11 gene is fused to the NUP98 gene in acute myeloid leukemia with t(2;11)(q31;p15). Cancer Res 2002; 62: 33-37.
-
(2002)
Cancer Res
, vol.62
, pp. 33-37
-
-
Taketani, T.1
Taki, T.2
Shibuya, N.3
Ito, E.4
Kitazawa, J.5
Terui, K.6
-
91
-
-
0037102313
-
Novel NUP98- HOXC11 fusion gene resulted from a chromosomal break within exon 1 of HOXC11 in acute myeloid leukemia with t(11;12)(p15;q13)
-
Taketani T, Taki T, Shibuya N, Kikuchi A, Hanada R, Hayashi Y. Novel NUP98- HOXC11 fusion gene resulted from a chromosomal break within exon 1 of HOXC11 in acute myeloid leukemia with t(11;12)(p15;q13). Cancer Res 2002; 62: 4571-4574.
-
(2002)
Cancer Res
, vol.62
, pp. 4571-4574
-
-
Taketani, T.1
Taki, T.2
Shibuya, N.3
Kikuchi, A.4
Hanada, R.5
Hayashi, Y.6
-
92
-
-
1342304050
-
Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1
-
Pineault N, Abramovich C, Ohta H, Humphries RK. Differential and common leukemogenic potentials of multiple NUP98-Hox fusion proteins alone or with Meis1. Mol Cell Biol 2004; 24: 1907-1917.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 1907-1917
-
-
Pineault, N.1
Abramovich, C.2
Ohta, H.3
Humphries, R.K.4
-
93
-
-
33746620006
-
The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia
-
Palmqvist L, Argiropoulos B, Pineault N, Abramovich C, Sly LM, Krystal G et al. The Flt3 receptor tyrosine kinase collaborates with NUP98-HOX fusions in acute myeloid leukemia. Blood 2006; 108: 1030-1036.
-
(2006)
Blood
, vol.108
, pp. 1030-1036
-
-
Palmqvist, L.1
Argiropoulos, B.2
Pineault, N.3
Abramovich, C.4
Sly, L.M.5
Krystal, G.6
-
94
-
-
0035253860
-
NUP98- HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice
-
Kroon E, Thorsteinsdottir U, Mayotte N, Nakamura T, Sauvageau G. NUP98- HOXA9 expression in hemopoietic stem cells induces chronic and acute myeloid leukemias in mice. EMBO J 2001; 20: 350-361.
-
(2001)
EMBO J
, vol.20
, pp. 350-361
-
-
Kroon, E.1
Thorsteinsdottir, U.2
Mayotte, N.3
Nakamura, T.4
Sauvageau, G.5
-
95
-
-
0037804796
-
Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1
-
Pineault N, Buske C, Feuring-Buske M, Abramovich C, Rosten P, Hogge DE et al. Induction of acute myeloid leukemia in mice by the human leukemia-specific fusion gene NUP98-HOXD13 in concert with Meis1. Blood 2003; 101: 4529-4538.
-
(2003)
Blood
, vol.101
, pp. 4529-4538
-
-
Pineault, N.1
Buske, C.2
Feuring-Buske, M.3
Abramovich, C.4
Rosten, P.5
Hogge, D.E.6
-
96
-
-
68049142925
-
Acute myeloid leukemia with NUP98-HOXC13 fusion and FLT3 internal tandem duplication mutation: Case report and literature review
-
Tosic N, Stojiljkovic M, Colovic N, Colovic M, Pavlovic S. Acute myeloid leukemia with NUP98-HOXC13 fusion and FLT3 internal tandem duplication mutation: case report and literature review. Cancer Genet Cytogenet 2009; 193: 98-103.
-
(2009)
Cancer Genet Cytogenet
, vol.193
, pp. 98-103
-
-
Tosic, N.1
Stojiljkovic, M.2
Colovic, N.3
Colovic, M.4
Pavlovic, S.5
-
97
-
-
67650770689
-
The molecular biology of mixed lineage leukemia
-
Slany RK. The molecular biology of mixed lineage leukemia. Haematol-Hematol J 2009; 94: 984-993.
-
(2009)
Haematol-Hematol J
, vol.94
, pp. 984-993
-
-
Slany, R.K.1
-
98
-
-
68749120703
-
New insights to the MLL recombinome of acute leukemias
-
Meyer C, Kowarz E, Hofmann J, Renneville A, Zuna J, Trka J et al. New insights to the MLL recombinome of acute leukemias. Leukemia 2009; 23: 1490-1499.
-
(2009)
Leukemia
, vol.23
, pp. 1490-1499
-
-
Meyer, C.1
Kowarz, E.2
Hofmann, J.3
Renneville, A.4
Zuna, J.5
Trka, J.6
-
99
-
-
18744373853
-
MLL targets SET domain methyltransferase activity to Hox gene promoters
-
Milne TA, Briggs SD, Brock HW, Martin ME, Gibbs D, Allis CD et al. MLL targets SET domain methyltransferase activity to Hox gene promoters. Mol Cell 2002; 10: 1107-1117.
-
(2002)
Mol Cell
, vol.10
, pp. 1107-1117
-
-
Milne, T.A.1
Briggs, S.D.2
Brock, H.W.3
Martin, M.E.4
Gibbs, D.5
Allis, C.D.6
-
100
-
-
77957891990
-
In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: Early gene expression profiling reveals possible drug target in AML
-
Abdul-Nabi AM, Yassin ER, Varghese N, Deshmukh H, Yaseen NR. In vitro transformation of primary human CD34+ cells by AML fusion oncogenes: early gene expression profiling reveals possible drug target in AML. PLoS ONE 2010; 5: e12464.
-
(2010)
PLoS ONE
, vol.5
-
-
Abdul-Nabi, A.M.1
Yassin, E.R.2
Varghese, N.3
Deshmukh, H.4
Yaseen, N.R.5
-
101
-
-
0041370095
-
Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9
-
Ayton PM, Cleary ML. Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9. Genes Dev 2003; 17: 2298-2307.
-
(2003)
Genes Dev
, vol.17
, pp. 2298-2307
-
-
Ayton, P.M.1
Cleary, M.L.2
-
102
-
-
33750951686
-
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model
-
Bansal D, Scholl C, Frohling S, Mcdowell E, Lee BH, Dohner K et al. Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proc Natl Acad Sci USA 2006; 103: 16924-16929.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16924-16929
-
-
Bansal, D.1
Scholl, C.2
Frohling, S.3
McDowell, E.4
Lee, B.H.5
Dohner, K.6
-
103
-
-
33750951686
-
Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model
-
Bansal D, Scholl C, Fröhling S, Mcdowell E, Lee BH, Döhner K et al. Cdx4 dysregulates Hox gene expression and generates acute myeloid leukemia alone and in cooperation with Meis1a in a murine model. Proc Natl Acad Sci USA 2006; 103: 16924-16929.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 16924-16929
-
-
Bansal, D.1
Scholl, C.2
Fröhling, S.3
McDowell, E.4
Lee, B.H.5
Döhner, K.6
-
104
-
-
73349090569
-
Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: Towards definition of a new leukaemia entity
-
Rau R, Brown P. Nucleophosmin (NPM1) mutations in adult and childhood acute myeloid leukaemia: towards definition of a new leukaemia entity. Hematol Oncol 2009; 27: 171-181.
-
(2009)
Hematol Oncol
, vol.27
, pp. 171-181
-
-
Rau, R.1
Brown, P.2
-
105
-
-
19944427850
-
Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype
-
Falini B, Mecucci C, Tiacci E, Alcalay M, Rosati R, Pasqualucci L et al. Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype. N Engl J Med 2005; 352: 254-266.
-
(2005)
N Engl J Med
, vol.352
, pp. 254-266
-
-
Falini, B.1
Mecucci, C.2
Tiacci, E.3
Alcalay, M.4
Rosati, R.5
Pasqualucci, L.6
-
106
-
-
33646557337
-
Prevelance and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML)
-
Thiede C, Koch S, Creutzig E, Steudel C, Lllmer T, Schiach M et al. Prevelance and prognostic impact of NPM1 mutations in 1485 adult patients with acute myeloid leukemia (AML). Blood 2006; 107: 4011-4020.
-
(2006)
Blood
, vol.107
, pp. 4011-4020
-
-
Thiede, C.1
Koch, S.2
Creutzig, E.3
Steudel, C.4
Lllmer, T.5
Schiach, M.6
-
107
-
-
42949142189
-
Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
-
Schlenk RF, Dohner K, Krauter J, Frohling S, Corbacioglu A, Bullinger L et al. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008; 358: 1909-1918.
-
(2008)
N Engl J Med
, vol.358
, pp. 1909-1918
-
-
Schlenk, R.F.1
Dohner, K.2
Krauter, J.3
Frohling, S.4
Corbacioglu, A.5
Bullinger, L.6
-
108
-
-
34547954572
-
The incidence and clinical significance of nucleophosmin mutations in childhood AML
-
Brown P, Mcintyre E, Rau R, Meshinchi S, Lacayo N, Dahl G et al. The incidence and clinical significance of nucleophosmin mutations in childhood AML. Blood 2007; 110: 979-985.
-
(2007)
Blood
, vol.110
, pp. 979-985
-
-
Brown, P.1
McIntyre, E.2
Rau, R.3
Meshinchi, S.4
Lacayo, N.5
Dahl, G.6
-
109
-
-
60149088611
-
Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML
-
Hollink IHIM, Zwaan CM, Zimmermann M, Arentsen-Peters TCJM, Pieters R, Cloos J et al. Favorable prognostic impact of NPM1 gene mutations in childhood acute myeloid leukemia, with emphasis on cytogenetically normal AML. Leukemia 2009; 23: 262-270.
-
(2009)
Leukemia
, vol.23
, pp. 262-270
-
-
Hollink, I.H.I.M.1
Zwaan, C.M.2
Zimmermann, M.3
Arentsen-Peters, T.C.J.M.4
Pieters, R.5
Cloos, J.6
-
110
-
-
70350724838
-
Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: Molecular basis and clinical implications
-
Falini B, Bolli N, Liso A, Martelli MP, Mannucci R, Pileri S et al. Altered nucleophosmin transport in acute myeloid leukaemia with mutated NPM1: molecular basis and clinical implications. Leukemia 2009; 23: 1731-1743.
-
(2009)
Leukemia
, vol.23
, pp. 1731-1743
-
-
Falini, B.1
Bolli, N.2
Liso, A.3
Martelli, M.P.4
Mannucci, R.5
Pileri, S.6
-
111
-
-
34548125335
-
Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias
-
Mullighan CG, Kennedy A, Zhou X, Radtke I, Phillips LA, Shurtleff SA et al. Pediatric acute myeloid leukemia with NPM1 mutations is characterized by a gene expression profile with dysregulated HOX gene expression distinct from MLL-rearranged leukemias. Leukemia 2007; 21: 2000-2009.
-
(2007)
Leukemia
, vol.21
, pp. 2000-2009
-
-
Mullighan, C.G.1
Kennedy, A.2
Zhou, X.3
Radtke, I.4
Phillips, L.A.5
Shurtleff, S.A.6
-
112
-
-
79955469651
-
Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice
-
Vassiliou GS, Cooper JL, Rad R, Li J, Rice S, Uren A et al. Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice. Nat Genet 2011; 43: 470-475.
-
(2011)
Nat Genet
, vol.43
, pp. 470-475
-
-
Vassiliou, G.S.1
Cooper, J.L.2
Rad, R.3
Li, J.4
Rice, S.5
Uren, A.6
-
113
-
-
0038240453
-
Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: Dominance of HOX dysregulation
-
Ferrando AA, Armstrong SA, Neuberg DS, Sallan SE, Silverman LB, Korsmeyer SJ et al. Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation. Blood 2003; 102: 262-268.
-
(2003)
Blood
, vol.102
, pp. 262-268
-
-
Ferrando, A.A.1
Armstrong, S.A.2
Neuberg, D.S.3
Sallan, S.E.4
Silverman, L.B.5
Korsmeyer, S.J.6
-
114
-
-
0035864734
-
Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4: 11) abnormality
-
Rozovskaia T, Feinstein E, Mor O, Foa R, Blechman J, Nakamura T et al. Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4: 11) abnormality. Oncogene 2001; 20: 874-878.
-
(2001)
Oncogene
, vol.20
, pp. 874-878
-
-
Rozovskaia, T.1
Feinstein, E.2
Mor, O.3
Foa, R.4
Blechman, J.5
Nakamura, T.6
-
115
-
-
54549083228
-
H3K79 methylation profiles define murine and human MLL-AF4 Leukemias
-
Krivtsov AV, Feng Z, Lemieux ME, Faber J, Vempati S, Sinha AU et al. H3K79 methylation profiles define murine and human MLL-AF4 Leukemias. Cancer Cell 2008; 14: 355-368.
-
(2008)
Cancer Cell
, vol.14
, pp. 355-368
-
-
Krivtsov, A.V.1
Feng, Z.2
Lemieux, M.E.3
Faber, J.4
Vempati, S.5
Sinha, A.U.6
-
116
-
-
68349085602
-
MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures
-
Zangrando A, Dell'orto MC, Kronnie GT, Basso G. MLL rearrangements in pediatric acute lymphoblastic and myeloblastic leukemias: MLL specific and lineage specific signatures. BMC Med Genomics 2009; 2: 36.
-
(2009)
BMC Med Genomics
, vol.2
, pp. 36
-
-
Zangrando, A.1
Dell'Orto, M.C.2
Kronnie, G.T.3
Basso, G.4
-
117
-
-
27644484043
-
CALMAF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes
-
Dik WA, Brahim W, Braun C, Asnafi V, Dastugue N, Bernard OA et al. CALMAF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes. Leukemia 2005; 19: 1948-1957.
-
(2005)
Leukemia
, vol.19
, pp. 1948-1957
-
-
Dik, W.A.1
Brahim, W.2
Braun, C.3
Asnafi, V.4
Dastugue, N.5
Bernard, O.A.6
-
118
-
-
22044457152
-
HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL)
-
Soulier J, Clappier E, Cayuela JM, Regnault A, García- PeydróM, Dombret H et al. HOXA genes are included in genetic and biologic networks defining human acute T-cell leukemia (T-ALL). Blood 2005; 106: 274-286.
-
(2005)
Blood
, vol.106
, pp. 274-286
-
-
Soulier, J.1
Clappier, E.2
Cayuela, J.M.3
Regnault, A.4
García- Peydróm5
Dombret, H.6
-
119
-
-
20144363957
-
A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias
-
Speleman F, Cauwelier B, Dastugue N, Cools J, Verhasselt B, Poppe B et al. A new recurrent inversion, inv(7)(p15q34), leads to transcriptional activation of HOXA10 and HOXA11 in a subset of T-cell acute lymphoblastic leukemias. Leukemia 2005; 19: 358-366.
-
(2005)
Leukemia
, vol.19
, pp. 358-366
-
-
Speleman, F.1
Cauwelier, B.2
Dastugue, N.3
Cools, J.4
Verhasselt, B.5
Poppe, B.6
-
120
-
-
64849109765
-
The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia
-
Thoene S, Rawat VPS, Heilmeier B, Hoster E, Metzeler KH, Herold T et al. The homeobox gene CDX2 is aberrantly expressed and associated with an inferior prognosis in patients with acute lymphoblastic leukemia. Leukemia 2009; 23: 649-655.
-
(2009)
Leukemia
, vol.23
, pp. 649-655
-
-
Thoene, S.1
Rawat, V.P.S.2
Heilmeier, B.3
Hoster, E.4
Metzeler, K.H.5
Herold, T.6
-
121
-
-
0033569406
-
Molecular classification of cancer: Class discovery and class prediction by gene expression monitoring
-
Golub TR, Slonim DK, Tamayo P, Huard C, Gaasenbeek M, Mesirov JP et al. Molecular classification of cancer: class discovery and class prediction by gene expression monitoring. Science 1999; 286: 531-537.
-
(1999)
Science
, vol.286
, pp. 531-537
-
-
Golub, T.R.1
Slonim, D.K.2
Tamayo, P.3
Huard, C.4
Gaasenbeek, M.5
Mesirov, J.P.6
-
122
-
-
56249085551
-
HOX expression patterns identify a common signature for favorable AML
-
Andreeff M, Ruvolo V, Gadgil S, Zeng C, Coombes K, Chen W et al. HOX expression patterns identify a common signature for favorable AML. Leukemia 2008; 22: 2041-2047.
-
(2008)
Leukemia
, vol.22
, pp. 2041-2047
-
-
Andreeff, M.1
Ruvolo, V.2
Gadgil, S.3
Zeng, C.4
Coombes, K.5
Chen, W.6
-
123
-
-
70349973619
-
The combined expression of HOXA4 and MEIS1 is an independent prognostic factor in patients with AML
-
Zangenberg M, Grubach L, Aggerholm A, Silkjaer T, Juhl-Christensen C, Nyvold CG et al. The combined expression of HOXA4 and MEIS1 is an independent prognostic factor in patients with AML. Eur J Haematol 2009; 83: 439-448.
-
(2009)
Eur J Haematol
, vol.83
, pp. 439-448
-
-
Zangenberg, M.1
Grubach, L.2
Aggerholm, A.3
Silkjaer, T.4
Juhl-Christensen, C.5
Nyvold, C.G.6
-
124
-
-
77956438566
-
Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells
-
Daniels TR, Neacato II, Rodriguez JA, Pandha HS, Morgan R, Penichet ML. Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells. Leukemia 2010; 24: 1555-1565.
-
(2010)
Leukemia
, vol.24
, pp. 1555-1565
-
-
Daniels, T.R.1
Neacato, I.I.2
Rodriguez, J.A.3
Pandha, H.S.4
Morgan, R.5
Penichet, M.L.6
-
125
-
-
34250835880
-
Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma
-
Morgan R, Pirard P, Shears L, Sohal S, Pettengell R, Pandha H. Antagonism of HOX/PBX dimer formation blocks the in vivo proliferation of melanoma. Cancer Res 2007; 67: 5806-5813.
-
(2007)
Cancer Res
, vol.67
, pp. 5806-5813
-
-
Morgan, R.1
Pirard, P.2
Shears, L.3
Sohal, S.4
Pettengell, R.5
Pandha, H.6
-
126
-
-
59649099697
-
HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer)
-
Plowright L, Harrington KJ, Pandha HS, Morgan R. HOX transcription factors are potential therapeutic targets in non-small-cell lung cancer (targeting HOX genes in lung cancer). Br J Cancer 2009; 100: 470-475.
-
(2009)
Br J Cancer
, vol.100
, pp. 470-475
-
-
Plowright, L.1
Harrington, K.J.2
Pandha, H.S.3
Morgan, R.4
-
127
-
-
53449098713
-
Disrupting the interaction between HOX and PBX causes necrotic and apoptotic cell death in the renal cancer lines CaKi-2 and 769-P
-
Shears L, Plowright L, Harrington K, Pandha H, Morgan R. Disrupting the interaction between HOX and PBX causes necrotic and apoptotic cell death in the renal cancer lines CaKi-2 and 769-P. J Urol 2008; 180: N2196-N2201.
-
(2008)
J Urol
, vol.180
-
-
Shears, L.1
Plowright, L.2
Harrington, K.3
Pandha, H.4
Morgan, R.5
-
128
-
-
77951151837
-
Targeting HOX and PBX transcription factors in ovarian cancer
-
Morgan R, Plowright L, Harrington K, Michael A, Pandha H. Targeting HOX and PBX transcription factors in ovarian cancer. BMC Cancer 2010; 10: 89.
-
(2010)
BMC Cancer
, vol.10
, pp. 89
-
-
Morgan, R.1
Plowright, L.2
Harrington, K.3
Michael, A.4
Pandha, H.5
-
129
-
-
68049131431
-
Regulator of calcineurin 1 modulates cancer cell migration in vitro
-
Espinosa AV, Shinohara M, Porchia LM, Chung YJ, Mccarty S, Saji M et al. Regulator of calcineurin 1 modulates cancer cell migration in vitro. Clin Exp Metastasis 2009; 26: 517-526.
-
(2009)
Clin Exp Metastasis
, vol.26
, pp. 517-526
-
-
Espinosa, A.V.1
Shinohara, M.2
Porchia, L.M.3
Chung, Y.J.4
McCarty, S.5
Saji, M.6
|