Aberrant Otx2 expression enhances migration and induces ectopic proliferation of hindbrain neuronal progenitor cells

PLoS ONE

Volumn 7, Issue 4, 2012, Pages

  Wortham, Matthew ^a   Jin, Genglin ^a   Sun, Julia Lailai ^a   Bigner, Darell D ^a   He, Yiping ^a   Yan, Hai ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR OTX2; WNT PROTEIN; OTX2 PROTEIN, MOUSE; SHH PROTEIN, MOUSE; TRANSCRIPTION FACTOR OTX;

ADULTHOOD; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN REGION; BRAIN STEM; CANCER STEM CELL; CARCINOGENESIS; CELL DIFFERENTIATION; CELL LINEAGE; CELL MIGRATION; CELL PROLIFERATION; CELL SPECIFICITY; CELL TRANSFORMATION; CONTROLLED STUDY; ECTOPIC TISSUE; EXTERNAL GRANULE LAYER; GRANULE CELL; HYPERPLASIA; MEDULLOBLASTOMA; MOUSE; NEURAL STEM CELL; NONHUMAN; PATHOPHYSIOLOGY; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RHOMBENCEPHALON; WHITE MATTER; ANIMAL; CELL MOTION; CEREBELLUM; CYTOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; NERVE CELL; PATHOLOGY; REPRODUCIBILITY; SIGNAL TRANSDUCTION;

ANIMALIA; MUS;

ANIMALS; CELL DIFFERENTIATION; CELL MOVEMENT; CELL PROLIFERATION; CEREBELLUM; FEMALE; GENE EXPRESSION REGULATION; HEDGEHOG PROTEINS; HUMANS; HYPERPLASIA; MEDULLOBLASTOMA; MICE; NEURAL STEM CELLS; NEURONS; OTX TRANSCRIPTION FACTORS; REPRODUCIBILITY OF RESULTS; RHOMBENCEPHALON; SIGNAL TRANSDUCTION;

EID: 84860470958     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036211     Document Type: Article

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