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Volumn 88, Issue 8, 2010, Pages 653-669

An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure

Author keywords

Craniorachischisis; Exencephaly; Mouse model; Neural tube defect; Spina bifida

Indexed keywords

INOSITOL; PROTEINASE ACTIVATED RECEPTOR;

EID: 77955649698     PISSN: 15420752     EISSN: 15420760     Source Type: Journal    
DOI: 10.1002/bdra.20676     Document Type: Review
Times cited : (271)

References (149)
  • 1
    • 14044269542 scopus 로고    scopus 로고
    • CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L
    • Banting GS, Barak O, Ames TM, et al. 2005. CECR2, a protein involved in neurulation, forms a novel chromatin remodeling complex with SNF2L. Hum Mol Genet 14:513-524.
    • (2005) Hum Mol Genet , vol.14 , pp. 513-524
    • Banting, G.S.1    Barak, O.2    Ames, T.M.3
  • 2
    • 0036471326 scopus 로고    scopus 로고
    • Folic acid prevents exencephaly in Cited2 deficient mice
    • Barbera JP, Rodriguez TA, Greene ND, et al. 2002. Folic acid prevents exencephaly in Cited2 deficient mice. Hum Mol Genet 11:283-293.
    • (2002) Hum Mol Genet , vol.11 , pp. 283-293
    • Barbera, J.P.1    Rodriguez, T.A.2    Greene, N.D.3
  • 3
    • 0032918003 scopus 로고    scopus 로고
    • Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, Men1
    • Bassett JH, Rashbass P, Harding B, et al. 1999. Studies of the murine homolog of the multiple endocrine neoplasia type 1 (MEN1) gene, Men1. J Bone Miner Res 14:3-10.
    • (1999) J Bone Miner Res , vol.14 , pp. 3-10
    • Bassett, J.H.1    Rashbass, P.2    Harding, B.3
  • 4
    • 65349083724 scopus 로고    scopus 로고
    • Insights into metabolic mechanisms underlying folate-responsive neural tube defects: A minireview
    • Beaudin AE, Stover PJ. 2009. Insights into metabolic mechanisms underlying folate-responsive neural tube defects: a minireview. Birth Defects Res A Clin Mol Teratol 85:274-284.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 274-284
    • Beaudin, A.E.1    Stover, P.J.2
  • 5
    • 0037684907 scopus 로고    scopus 로고
    • Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs
    • Bertolino P, Radovanovic I, Casse H, et al. 2003. Genetic ablation of the tumor suppressor menin causes lethality at mid-gestation with defects in multiple organs. Mech Dev 120:549-560.
    • (2003) Mech Dev , vol.120 , pp. 549-560
    • Bertolino, P.1    Radovanovic, I.2    Casse, H.3
  • 6
    • 70350023756 scopus 로고    scopus 로고
    • CBP/p300 and associated transcriptional co-activators exhibit distinct expression patterns during murine craniofacial and neural tube development
    • Bhattacherjee V, Horn KH, Singh S, et al. 2009. CBP/p300 and associated transcriptional co-activators exhibit distinct expression patterns during murine craniofacial and neural tube development. Int J Dev Biol 53:1097-1104.
    • (2009) Int J Dev Biol , vol.53 , pp. 1097-1104
    • Bhattacherjee, V.1    Horn, K.H.2    Singh, S.3
  • 7
    • 65349184462 scopus 로고    scopus 로고
    • Folic acid, methylation and neural tube closure in humans
    • Blom HJ. 2009. Folic acid, methylation and neural tube closure in humans. Birth Defects Res A Clin Mol Teratol 85:295-302.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 295-302
    • Blom, H.J.1
  • 8
    • 55349119916 scopus 로고    scopus 로고
    • Sall1, Sall2, and Sall4 are required for neural tube closure in mice
    • Bohm J, Buck A, Borozdin W, et al. 2008. Sall1, Sall2, and Sall4 are required for neural tube closure in mice. Am J Pathol 173:1455-1463.
    • (2008) Am J Pathol , vol.173 , pp. 1455-1463
    • Bohm, J.1    Buck, A.2    Borozdin, W.3
  • 10
    • 0034190659 scopus 로고    scopus 로고
    • 5,10-methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review
    • Botto LD, Yang Q. 2000. 5,10-methylenetetrahydrofolate reductase gene variants and congenital anomalies: A HuGE review. Am J Epidemiol 151:862-877.
    • (2000) Am J Epidemiol , vol.151 , pp. 862-877
    • Botto, L.D.1    Yang, Q.2
  • 11
    • 47749142440 scopus 로고    scopus 로고
    • Trends in the postfortification prevalence of spina bifida and anencephaly in the United States
    • National Birth Defects Prevention Network
    • Boulet SL, Yang Q, Mai C, et al.; National Birth Defects Prevention Network. 2008. Trends in the postfortification prevalence of spina bifida and anencephaly in the United States. Birth Defects Res A Clin Mol Teratol 82:527-532.
    • (2008) Birth Defects Res A Clin Mol Teratol , vol.82 , pp. 527-532
    • Boulet, S.L.1    Yang, Q.2    Mai, C.3
  • 12
    • 65349170888 scopus 로고    scopus 로고
    • Neural tube defects in Australia: Trends in encephaloceles and other neural tube defects before and after promotion of folic acid supplementation and voluntary food fortification
    • Bower C, D'Antoine H, Stanley FJ. 2009. Neural tube defects in Australia: trends in encephaloceles and other neural tube defects before and after promotion of folic acid supplementation and voluntary food fortification. Birth Defects Res A Clin Mol Teratol 85:269-273.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 269-273
    • Bower, C.1    D'Antoine, H.2    Stanley, F.J.3
  • 13
    • 34247646897 scopus 로고    scopus 로고
    • Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos
    • Bu P, Evrard YA, Lozano G, et al. 2007. Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos. Mol Cell Biol 27:3405-3416.
    • (2007) Mol Cell Biol , vol.27 , pp. 3405-3416
    • Bu, P.1    Evrard, Y.A.2    Lozano, G.3
  • 14
    • 74049143122 scopus 로고    scopus 로고
    • Local protease signaling contributes to neural tube closure in the mouse embryo
    • Camerer E, Barker A, Duong DN, et al. 2010. Local protease signaling contributes to neural tube closure in the mouse embryo. Dev Cell 18:25-38.
    • (2010) Dev Cell , vol.18 , pp. 25-38
    • Camerer, E.1    Barker, A.2    Duong, D.N.3
  • 15
    • 0032695776 scopus 로고    scopus 로고
    • Crooked tail (Cd) models human folate-responsive neural tube defects
    • Carter M, Ulrich S, Oofuji Y, et al. 1999. Crooked tail (Cd) models human folate-responsive neural tube defects. Hum Mol Genet 8:199-204.
    • (1999) Hum Mol Genet , vol.8 , pp. 199-204
    • Carter, M.1    Ulrich, S.2    Oofuji, Y.3
  • 16
    • 58149239764 scopus 로고    scopus 로고
    • Bmp2 is required for cephalic neural tube closure in the mouse
    • Castranio T, Mishina Y. 2009. Bmp2 is required for cephalic neural tube closure in the mouse. Dev Dyn 238:110-122.
    • (2009) Dev Dyn , vol.238 , pp. 110-122
    • Castranio, T.1    Mishina, Y.2
  • 17
    • 47749101693 scopus 로고    scopus 로고
    • Inositol supplementation in pregnancies at risk of apparently folate-resistant NTDs
    • Cavalli P, Tedoldi S, Riboli B, et al. 2008. Inositol supplementation in pregnancies at risk of apparently folate-resistant NTDs. Birth Defects Res A Clin Mol Teratol 82:540-542.
    • (2008) Birth Defects Res A Clin Mol Teratol , vol.82 , pp. 540-542
    • Cavalli, P.1    Tedoldi, S.2    Riboli, B.3
  • 18
    • 0028206583 scopus 로고
    • Prevention of spinal neural tube defects in the curly tail mouse mutant by a specific effect of retinoic acid
    • Chen WH, Morriss-Kay GM, Copp AJ, et al. 1994. Prevention of spinal neural tube defects in the curly tail mouse mutant by a specific effect of retinoic acid. Dev Dyn 199:93-102.
    • (1994) Dev Dyn , vol.199 , pp. 93-102
    • Chen, W.H.1    Morriss-Kay, G.M.2    Copp, A.J.3
  • 19
    • 0141814680 scopus 로고    scopus 로고
    • Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice
    • Cheng HL, Mostoslavsky R, Saito S, et al. 2003. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A 100:10794-10799.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 10794-10799
    • Cheng, H.L.1    Mostoslavsky, R.2    Saito, S.3
  • 20
    • 0036712213 scopus 로고    scopus 로고
    • D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects
    • Cogram P, Tesh S, Tesh J, et al. 2002. D-chiro-inositol is more effective than myo-inositol in preventing folate-resistant mouse neural tube defects. Hum Reprod 17:2451-2458.
    • (2002) Hum Reprod , vol.17 , pp. 2451-2458
    • Cogram, P.1    Tesh, S.2    Tesh, J.3
  • 21
    • 0036334452 scopus 로고    scopus 로고
    • Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski-/- Mice
    • Colmenares C, Heilstedt HA, Shaffer LG, et al. 2002. Loss of the SKI proto-oncogene in individuals affected with 1p36 deletion syndrome is predicted by strain-dependent defects in Ski-/- mice. Nat Genet 30:106-109.
    • (2002) Nat Genet , vol.30 , pp. 106-109
    • Colmenares, C.1    Heilstedt, H.A.2    Shaffer, L.G.3
  • 23
    • 28444460247 scopus 로고    scopus 로고
    • Neurulation in the cranial region-normal and abnormal
    • Copp AJ. 2005. Neurulation in the cranial region-normal and abnormal. J Anat 207:623-635.
    • (2005) J Anat , vol.207 , pp. 623-635
    • Copp, A.J.1
  • 24
    • 74049119727 scopus 로고    scopus 로고
    • Defining a particular pathway of neural tube closure
    • Copp AJ, Greene ND. 2010. Defining a particular pathway of neural tube closure. Dev Cell 18:1-2.
    • (2010) Dev Cell , vol.18 , pp. 1-2
    • Copp, A.J.1    Greene, N.D.2
  • 25
    • 58049208156 scopus 로고    scopus 로고
    • Defective ciliogenesis, embryonic lethality and severe impairment of the sonic hedgehog pathway caused by inactivation of the mouse complex a intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
    • Cortellino S, Wang C, Wang B, et al. 2009. Defective ciliogenesis, embryonic lethality and severe impairment of the sonic hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4. Dev Biol 325:225-237.
    • (2009) Dev Biol , vol.325 , pp. 225-237
    • Cortellino, S.1    Wang, C.2    Wang, B.3
  • 26
    • 0027080461 scopus 로고
    • Prevention of the first occurrence of neuraltube defects by periconceptional vitamin supplementation
    • Czeizel AE, Dudas I. 1992. Prevention of the first occurrence of neuraltube defects by periconceptional vitamin supplementation. N Engl J Med 327:1832-1835.
    • (1992) N Engl J Med , vol.327 , pp. 1832-1835
    • Czeizel, A.E.1    Dudas, I.2
  • 27
    • 20444424616 scopus 로고    scopus 로고
    • Human neural tube defects: Developmental biology, epidemiology, and genetics
    • Detrait ER, George TM, Etchevers HC, et al. 2005. Human neural tube defects: developmental biology, epidemiology, and genetics. Neurotoxicol Teratol 27:515-524.
    • (2005) Neurotoxicol Teratol , vol.27 , pp. 515-524
    • Detrait, E.R.1    George, T.M.2    Etchevers, H.C.3
  • 28
    • 0025875441 scopus 로고
    • Do familial neural tube defects breed true?
    • Drainer E, May HM, Tolmie JL, et al. 1991. Do familial neural tube defects breed true? J Med Genet 28:605-608.
    • (1991) J Med Genet , vol.28 , pp. 605-608
    • Drainer, E.1    May, H.M.2    Tolmie, J.L.3
  • 29
    • 33748172788 scopus 로고    scopus 로고
    • Expression analysis of the novel gene collagen triple helix repeat containing-1 (Cthrc1)
    • Durmus T, LeClair RJ, Park KS, et al. 2006. Expression analysis of the novel gene collagen triple helix repeat containing-1 (Cthrc1). Gene Expr Patterns 6:935-940.
    • (2006) Gene Expr Patterns , vol.6 , pp. 935-940
    • Durmus, T.1    LeClair, R.J.2    Park, K.S.3
  • 30
    • 58549088015 scopus 로고    scopus 로고
    • Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development
    • Enkhmandakh B, Makeyev AV, Erdenechimeg L, et al. 2009. Essential functions of the Williams-Beuren syndrome-associated TFII-I genes in embryonic development. Proc Natl Acad Sci U S A 106:181-186.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 181-186
    • Enkhmandakh, B.1    Makeyev, A.V.2    Erdenechimeg, L.3
  • 31
    • 33751382326 scopus 로고    scopus 로고
    • Parallel changes in metabolite and expression profiles in crooked-tail mutant and folate-reduced wild-type mice
    • Ernest S, Carter M, Shao H, et al. 2006. Parallel changes in metabolite and expression profiles in crooked-tail mutant and folate-reduced wild-type mice. Hum Mol Genet 15:3387-3393.
    • (2006) Hum Mol Genet , vol.15 , pp. 3387-3393
    • Ernest, S.1    Carter, M.2    Shao, H.3
  • 32
    • 0027455468 scopus 로고
    • Methionine but not folinic acid or vitamin B-12 alters the frequency of neural tube defects in Axd mutant mice
    • published erratum appears in J Nutr 1993;123:973-974
    • Essien FB, Wannberg SL. 1993. Methionine but not folinic acid or vitamin B-12 alters the frequency of neural tube defects in Axd mutant mice [published erratum appears in J Nutr 1993;123:973-974]. J Nutr 123:27-34.
    • (1993) J Nutr , vol.123 , pp. 27-34
    • Essien, F.B.1    Wannberg, S.L.2
  • 33
    • 57149114315 scopus 로고    scopus 로고
    • Murine Dishevelled 3 functions in redundant pathways with Dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development
    • Etheridge SL, Ray S, Li S, et al. 2008. Murine Dishevelled 3 functions in redundant pathways with Dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet 4:e1000259.
    • (2008) PLoS Genet , vol.4
    • Etheridge, S.L.1    Ray, S.2    Li, S.3
  • 34
    • 77955058518 scopus 로고
    • The inheritance of liability to certain diseases, estimated from the incidence among relatives
    • Falconer DS. 1965. The inheritance of liability to certain diseases, estimated from the incidence among relatives. Ann Hum Genet 29:51-76.
    • (1965) Ann Hum Genet , vol.29 , pp. 51-76
    • Falconer, D.S.1
  • 35
    • 34347344990 scopus 로고    scopus 로고
    • Ambra1 regulates autophagy and development of the nervous system
    • Fimia GM, Stoykova A, Romagnoli A, et al. 2007. Ambra1 regulates autophagy and development of the nervous system. Nature 447:1121-1125.
    • (2007) Nature , vol.447 , pp. 1121-1125
    • Fimia, G.M.1    Stoykova, A.2    Romagnoli, A.3
  • 36
    • 0032568871 scopus 로고    scopus 로고
    • Embryonic folate metabolism and mouse neural tube defects
    • Fleming A, Copp AJ. 1998. Embryonic folate metabolism and mouse neural tube defects. Science 280:2107-2109.
    • (1998) Science , vol.280 , pp. 2107-2109
    • Fleming, A.1    Copp, A.J.2
  • 37
    • 77149133720 scopus 로고    scopus 로고
    • ATX expression and LPA signalling are vital for the development of the nervous system
    • Fotopoulou S, Oikonomou N, Grigorieva E, et al. 2010. ATX expression and LPA signalling are vital for the development of the nervous system. Dev Biol 339:451-464.
    • (2010) Dev Biol , vol.339 , pp. 451-464
    • Fotopoulou, S.1    Oikonomou, N.2    Grigorieva, E.3
  • 38
    • 58149111109 scopus 로고    scopus 로고
    • Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo
    • Garcia-Garcia MJ, Shibata M, Anderson KV, et al. 2008. Chato, a KRAB zinc-finger protein, regulates convergent extension in the mouse embryo. Development 135:3053-3062.
    • (2008) Development , vol.135 , pp. 3053-3062
    • Garcia-Garcia, M.J.1    Shibata, M.2    Anderson, K.V.3
  • 39
    • 65349191179 scopus 로고    scopus 로고
    • Mechanistic insights into folate supplementation from Crooked tail and other NTD-prone mutant mice
    • Gray JD, Ross ME. 2009. Mechanistic insights into folate supplementation from Crooked tail and other NTD-prone mutant mice. Birth Defects Res A Clin Mol Teratol 85:314-321.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 314-321
    • Gray, J.D.1    Ross, M.E.2
  • 40
    • 70349651962 scopus 로고    scopus 로고
    • The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development
    • Gray RS, Abitua PB, Wlodarczyk BJ, et al. 2009. The planar cell polarity effector Fuz is essential for targeted membrane trafficking, ciliogenesis and mouse embryonic development. Nat Cell Biol 11:1225-1232.
    • (2009) Nat Cell Biol , vol.11 , pp. 1225-1232
    • Gray, R.S.1    Abitua, P.B.2    Wlodarczyk, B.J.3
  • 41
    • 0031033593 scopus 로고    scopus 로고
    • Inositol prevents folate-resistant neural tube defects in the mouse
    • Greene ND, Copp AJ. 1997. Inositol prevents folate-resistant neural tube defects in the mouse. Nat Med 3:60-66.
    • (1997) Nat Med , vol.3 , pp. 60-66
    • Greene, N.D.1    Copp, A.J.2
  • 42
    • 35348855579 scopus 로고    scopus 로고
    • High prevalence of NTDs in Shanxi province: A combined epidemiological approach
    • Gu X, Lin L, Zheng X, et al. 2007. High prevalence of NTDs in Shanxi province: a combined epidemiological approach. Birth Defects Res A Clin Mol Teratol 79:702-707.
    • (2007) Birth Defects Res A Clin Mol Teratol , vol.79 , pp. 702-707
    • Gu, X.1    Lin, L.2    Zheng, X.3
  • 43
    • 35448973405 scopus 로고    scopus 로고
    • Increased expression of Grainyhead-like-3 rescues spina bifida in a folate-resistant mouse model
    • Gustavsson P, Greene ND, Lad D, et al. 2007. Increased expression of Grainyhead-like-3 rescues spina bifida in a folate-resistant mouse model. Hum Mol Genet 16:2640-2646.
    • (2007) Hum Mol Genet , vol.16 , pp. 2640-2646
    • Gustavsson, P.1    Greene, N.D.2    Lad, D.3
  • 44
    • 67349263098 scopus 로고    scopus 로고
    • The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis
    • Gyuris A, Donovan DJ, Seymour KA, et al. 2009. The chromatin-targeting protein Brd2 is required for neural tube closure and embryogenesis. Biochim Biophys Acta 1789:413-421.
    • (2009) Biochim Biophys Acta , vol.1789 , pp. 413-421
    • Gyuris, A.1    Donovan, D.J.2    Seymour, K.A.3
  • 45
    • 65349175626 scopus 로고    scopus 로고
    • Insights into prevention of human neural tube defects by folic acid arising from consideration of mouse mutants
    • Harris MJ. 2009. Insights into prevention of human neural tube defects by folic acid arising from consideration of mouse mutants. Birth Defects Res A Clin Mol Teratol 85:331-339.
    • (2009) Birth Defects Res A Clin Mol Teratol , vol.85 , pp. 331-339
    • Harris, M.J.1
  • 46
    • 33947172588 scopus 로고    scopus 로고
    • Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects
    • Harris MJ, Juriloff DM. 2007. Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects. Birth Defects Res A Clin Mol Teratol 79:187-210.
    • (2007) Birth Defects Res A Clin Mol Teratol , vol.79 , pp. 187-210
    • Harris, M.J.1    Juriloff, D.M.2
  • 47
    • 23944479692 scopus 로고    scopus 로고
    • Maternal diet alters exencephaly frequency in SELH/Bc strain mouse embryos
    • Harris MJ, Juriloff DM. 2005. Maternal diet alters exencephaly frequency in SELH/Bc strain mouse embryos. Birth Defects Res A Clin Mol Teratol 73:532-540.
    • (2005) Birth Defects Res A Clin Mol Teratol , vol.73 , pp. 532-540
    • Harris, M.J.1    Juriloff, D.M.2
  • 48
    • 0033503556 scopus 로고    scopus 로고
    • Mini-review: Toward understanding mechanisms of genetic neural tube defects in mice
    • Harris MJ, Juriloff DM. 1999. Mini-review: toward understanding mechanisms of genetic neural tube defects in mice. Teratology 60:292-305.
    • (1999) Teratology , vol.60 , pp. 292-305
    • Harris, M.J.1    Juriloff, D.M.2
  • 49
    • 0036333103 scopus 로고    scopus 로고
    • Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice
    • Hata K, Okano M, Lei H, et al. 2002. Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development; 129:1983-1993.
    • (2002) Development , vol.129 , pp. 1983-1993
    • Hata, K.1    Okano, M.2    Lei, H.3
  • 50
    • 0034617376 scopus 로고    scopus 로고
    • Hypertolerance to morphine in G(z alpha)-deficient mice
    • Hendry IA, Kelleher KL, Bartlett SE, et al. 2000. Hypertolerance to morphine in G(z alpha)-deficient mice. Brain Res 870:10-19.
    • (2000) Brain Res , vol.870 , pp. 10-19
    • Hendry, I.A.1    Kelleher, K.L.2    Bartlett, S.E.3
  • 51
    • 70949085969 scopus 로고    scopus 로고
    • Planar cell polarity effector gene fuzzy regulates cilia formation and hedgehog signal transduction in mouse
    • Heydeck W, Zeng H, Liu A, et al. 2009. Planar cell polarity effector gene fuzzy regulates cilia formation and hedgehog signal transduction in mouse. Dev Dyn 238:3035-3042.
    • (2009) Dev Dyn , vol.238 , pp. 3035-3042
    • Heydeck, W.1    Zeng, H.2    Liu, A.3
  • 52
    • 60849116473 scopus 로고    scopus 로고
    • C2cd3 is required for cilia formation and hedgehog signaling in mouse
    • Hoover AN, Wynkoop A, Zeng H, et al. 2008. C2cd3 is required for cilia formation and hedgehog signaling in mouse. Development 135:4049-4058.
    • (2008) Development , vol.135 , pp. 4049-4058
    • Hoover, A.N.1    Wynkoop, A.2    Zeng, H.3
  • 53
    • 53349162226 scopus 로고    scopus 로고
    • LUZP deficiency affects neural tube closure during brain development
    • Hsu CY, Chang NC, Lee MW, et al. 2008. LUZP deficiency affects neural tube closure during brain development. Biochem Biophys Res Commun 376:466-471.
    • (2008) Biochem Biophys Res Commun , vol.376 , pp. 466-471
    • Hsu, C.Y.1    Chang, N.C.2    Lee, M.W.3
  • 54
    • 69349095810 scopus 로고    scopus 로고
    • INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse
    • Jacoby M, Cox JJ, Gayral S, et al. 2009. INPP5E mutations cause primary cilium signaling defects, ciliary instability and ciliopathies in human and mouse. Nat Genet 41:1027-1031.
    • (2009) Nat Genet , vol.41 , pp. 1027-1031
    • Jacoby, M.1    Cox, J.J.2    Gayral, S.3
  • 55
    • 77951297947 scopus 로고    scopus 로고
    • Transgenerational developmental effects and genomic instability after X-irradiation of preimplantation embryos: Studies on two mouse strains
    • Jacquet P, Buset J, Neefs M, et al. 2010. Transgenerational developmental effects and genomic instability after X-irradiation of preimplantation embryos: studies on two mouse strains. Mutat Res 687:54-62.
    • (2010) Mutat Res , vol.687 , pp. 54-62
    • Jacquet, P.1    Buset, J.2    Neefs, M.3
  • 56
    • 67649371083 scopus 로고    scopus 로고
    • Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice
    • Jakubowski H, Perla-Kajan J, Finnell RH, et al. 2009. Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J 23:1721-1727.
    • (2009) FASEB J , vol.23 , pp. 1721-1727
    • Jakubowski, H.1    Perla-Kajan, J.2    Finnell, R.H.3
  • 57
    • 30744454595 scopus 로고    scopus 로고
    • Expression and functional analysis of Tgif during mouse midline development
    • Jin JZ, Gu S, McKinney P, et al. 2006. Expression and functional analysis of Tgif during mouse midline development. Dev Dyn 235:547-553.
    • (2006) Dev Dyn , vol.235 , pp. 547-553
    • Jin, J.Z.1    Gu, S.2    McKinney, P.3
  • 58
    • 33947310031 scopus 로고    scopus 로고
    • Environmental epigenomics and disease susceptibility
    • Jirtle RL, Skinner MK. 2007. Environmental epigenomics and disease susceptibility. Nat Rev Genet 8:253-262.
    • (2007) Nat Rev Genet , vol.8 , pp. 253-262
    • Jirtle, R.L.1    Skinner, M.K.2
  • 60
    • 33947153549 scopus 로고    scopus 로고
    • Congenic lines from SELH/Bc mice provide proof of principle of the genetic and developmental multifactorial threshold model for NTDs
    • Juriloff DM, Hoscheit JL, Harris MJ, et al. 2006. Congenic lines from SELH/Bc mice provide proof of principle of the genetic and developmental multifactorial threshold model for NTDs. Birth Defects Res A Clin Mol Teratol 76:148-149.
    • (2006) Birth Defects Res A Clin Mol Teratol , vol.76 , pp. 148-149
    • Juriloff, D.M.1    Hoscheit, J.L.2    Harris, M.J.3
  • 61
    • 0034807135 scopus 로고    scopus 로고
    • Multifactorial genetics of exencephaly in SELH/Bc mice
    • Juriloff DM, Gunn TM, Harris MJ, et al. 2001a. Multifactorial genetics of exencephaly in SELH/Bc mice. Teratology 64:189-200.
    • (2001) Teratology , vol.64 , pp. 189-200
    • Juriloff, D.M.1    Gunn, T.M.2    Harris, M.J.3
  • 62
    • 0034640007 scopus 로고    scopus 로고
    • Mouse models for neural tube closure defects
    • Juriloff DM, Harris MJ. 2000. Mouse models for neural tube closure defects. Hum Mol Genet 9:993-1000.
    • (2000) Hum Mol Genet , vol.9 , pp. 993-1000
    • Juriloff, D.M.1    Harris, M.J.2
  • 63
    • 0035016264 scopus 로고    scopus 로고
    • Unraveling the complex genetics of cleft lip in the mouse model
    • Juriloff DM, Harris MJ, Brown CJ., et al. 2001b. Unraveling the complex genetics of cleft lip in the mouse model. Mamm Genome 12:426-435.
    • (2001) Mamm Genome , vol.12 , pp. 426-435
    • Juriloff, D.M.1    Harris, M.J.2    Brown, C.J.3
  • 64
    • 35548976645 scopus 로고    scopus 로고
    • Transcription factor TEAD2 is involved in neural tube closure
    • Kaneko KJ, Kohn MJ, Liu C, et al. 2007. Transcription factor TEAD2 is involved in neural tube closure. Genesis 45:577-587.
    • (2007) Genesis , vol.45 , pp. 577-587
    • Kaneko, K.J.1    Kohn, M.J.2    Liu, C.3
  • 65
    • 0022490429 scopus 로고
    • Risks to sibs of probands with neural tube defects: Data for clinic populations in British Columbia
    • Keena B, Sadovnick AD, Baird PA, et al. 1986. Risks to sibs of probands with neural tube defects: Data for clinic populations in British Columbia. Am J Med Genet 25:563-573.
    • (1986) Am J Med Genet , vol.25 , pp. 563-573
    • Keena, B.1    Sadovnick, A.D.2    Baird, P.A.3
  • 66
    • 0034769937 scopus 로고    scopus 로고
    • Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development
    • Kim JK, Huh SO, Choi H, et al. 2001. Srg3, a mouse homolog of yeast SWI3, is essential for early embryogenesis and involved in brain development. Mol Cell Biol 21:7787-7795.
    • (2001) Mol Cell Biol , vol.21 , pp. 7787-7795
    • Kim, J.K.1    Huh, S.O.2    Choi, H.3
  • 67
    • 34347232361 scopus 로고    scopus 로고
    • Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression
    • Kim TH, Goodman J, Anderson KV, et al. 2007. Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression Dev Cell 13:87-102.
    • (2007) Dev Cell , vol.13 , pp. 87-102
    • Kim, T.H.1    Goodman, J.2    Anderson, K.V.3
  • 68
    • 66549088711 scopus 로고    scopus 로고
    • Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration
    • Kimura T, Sakai M, Tabu K, et al. 2009. Human synovial sarcoma proto-oncogene Syt is essential for early embryonic development through the regulation of cell migration. Lab Invest 89:645-656.
    • (2009) Lab Invest , vol.89 , pp. 645-656
    • Kimura, T.1    Sakai, M.2    Tabu, K.3
  • 69
    • 57349192021 scopus 로고    scopus 로고
    • Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects
    • Korstanje R, Desai J, Lazar G, et al. 2008. Quantitative trait loci affecting phenotypic variation in the vacuolated lens mouse mutant, a multigenic mouse model of neural tube defects. Physiol Genomics 35:296-304.
    • (2008) Physiol Genomics , vol.35 , pp. 296-304
    • Korstanje, R.1    Desai, J.2    Lazar, G.3
  • 70
    • 33845367070 scopus 로고    scopus 로고
    • Intragenic deletion of Tgif causes defects in brain development
    • Kuang C, Xiao Y, Yang L, et al. 2006. Intragenic deletion of Tgif causes defects in brain development. Hum Mol Genet 15:3508-3519.
    • (2006) Hum Mol Genet , vol.15 , pp. 3508-3519
    • Kuang, C.1    Xiao, Y.2    Yang, L.3
  • 71
    • 70349776908 scopus 로고    scopus 로고
    • Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: Relevance to genetic modifiers
    • Lemos MC, Harding B, Reed AA, et al. 2009. Genetic background influences embryonic lethality and the occurrence of neural tube defects in Men1 null mice: relevance to genetic modifiers. J Endocrinol 203:133-142.
    • (2009) J Endocrinol , vol.203 , pp. 133-142
    • Lemos, M.C.1    Harding, B.2    Reed, A.A.3
  • 72
    • 34447249019 scopus 로고    scopus 로고
    • An essential switch in subunit composition of a chromatin remodeling complex during neural development
    • Lessard J, Wu JI, Ranish JA, et al. 2007. An essential switch in subunit composition of a chromatin remodeling complex during neural development. Neuron 55:201-215.
    • (2007) Neuron , vol.55 , pp. 201-215
    • Lessard, J.1    Wu, J.I.2    Ranish, J.A.3
  • 73
    • 33646270883 scopus 로고    scopus 로고
    • Extremely high prevalence of neural tube defects in a 4-county area in Shanxi province, China
    • Li Z, Ren A, Zhang L, et al. 2006. Extremely high prevalence of neural tube defects in a 4-county area in Shanxi province, China. Birth Defects Res A Clin Mol Teratol 76:237-240.
    • (2006) Birth Defects Res A Clin Mol Teratol , vol.76 , pp. 237-240
    • Li, Z.1    Ren, A.2    Zhang, L.3
  • 74
    • 42149117852 scopus 로고    scopus 로고
    • Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos
    • DOI 10.1002/dvdy.21479
    • Lin W, Zhang Z, Srajer G, et al. 2008. Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos. Dev Dyn 237:928-940. (Pubitemid 351542291)
    • (2008) Developmental Dynamics , vol.237 , Issue.4 , pp. 928-940
    • Lin, W.1    Zhang, Z.2    Srajer, G.3    Yi, C.C.4    Huang, M.5    Phan, H.M.6    Dent, S.Y.R.7
  • 75
    • 33750475923 scopus 로고    scopus 로고
    • Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia
    • Lindhurst MJ, Fiermonte G, Song S, et al. 2006. Knockout of Slc25a19 causes mitochondrial thiamine pyrophosphate depletion, embryonic lethality, CNS malformations, and anemia Proc Natl Acad Sci U S A 103:15927-15932.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15927-15932
    • Lindhurst, M.J.1    Fiermonte, G.2    Song, S.3
  • 76
    • 37549025849 scopus 로고    scopus 로고
    • The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development
    • Lou DY, Dominguez I, Toselli P, et al. 2008. The alpha catalytic subunit of protein kinase CK2 is required for mouse embryonic development. Mol Cell Biol 28:131-139.
    • (2008) Mol Cell Biol , vol.28 , pp. 131-139
    • Lou, D.Y.1    Dominguez, I.2    Toselli, P.3
  • 77
    • 58049208169 scopus 로고    scopus 로고
    • The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure
    • Maller Schulman BR, Liang X, Stahlhut C, et al. 2008. The let-7 microRNA target gene, Mlin41/Trim71 is required for mouse embryonic survival and neural tube closure. Cell Cycle 7:3935-3942.
    • (2008) Cell Cycle , vol.7 , pp. 3935-3942
    • Maller Schulman, B.R.1    Liang, X.2    Stahlhut, C.3
  • 78
    • 0025122421 scopus 로고
    • Comparison of the incidence of 5-azacytidine-induced exencephaly between MT/HokIdr and slc:ICR mice
    • Matsuda M. 1990. Comparison of the incidence of 5-azacytidine-induced exencephaly between MT/HokIdr and slc:ICR mice. Teratology 41:147-154.
    • (1990) Teratology , vol.41 , pp. 147-154
    • Matsuda, M.1
  • 79
    • 41149143108 scopus 로고    scopus 로고
    • The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development
    • Matteson PG, Desai J, Korstanje R, et al. 2008. The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development. Proc Natl Acad Sci U S A 105:2088-2093.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 2088-2093
    • Matteson, P.G.1    Desai, J.2    Korstanje, R.3
  • 80
    • 0018654113 scopus 로고
    • Sib risk of anencephaly and spina bifida in British Columbia
    • McBride ML. 1979. Sib risk of anencephaly and spina bifida in British Columbia. Am J Med Genet 3:377-387.
    • (1979) Am J Med Genet , vol.3 , pp. 377-387
    • McBride, M.L.1
  • 81
    • 0032523777 scopus 로고    scopus 로고
    • Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite
    • McMahon JA, Takada S, Zimmerman LB, et al. 1998. Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite. Genes Dev 12:1438-1452.
    • (1998) Genes Dev , vol.12 , pp. 1438-1452
    • McMahon, J.A.1    Takada, S.2    Zimmerman, L.B.3
  • 82
    • 0025308557 scopus 로고
    • Phenotypic characterization of the transgenic mouse insertional mutation, legless
    • McNeish JD, Thayer J, Walling K, et al. 1990. Phenotypic characterization of the transgenic mouse insertional mutation, legless. J Exp Zool 253:151-162.
    • (1990) J Exp Zool , vol.253 , pp. 151-162
    • McNeish, J.D.1    Thayer, J.2    Walling, K.3
  • 83
    • 84862999072 scopus 로고    scopus 로고
    • Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure
    • sup pp 1-8
    • Merte J, Jensen D, Wright K, et al. 2010. Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure. Nat Cell Biol 12:41-6; sup pp 1-8.
    • (2010) Nat Cell Biol , vol.12 , pp. 41-46
    • Merte, J.1    Jensen, D.2    Wright, K.3
  • 84
    • 0003928465 scopus 로고    scopus 로고
    • MGI The Jackson Laboratory, Bar Harbor, Maine Accessed February 2010
    • MGI. 2010. Mouse Genome Informatics, The Jackson Laboratory, Bar Harbor, Maine. http://www.informatics.jax.org. Accessed February 2010.
    • (2010) Mouse Genome Informatics
  • 85
    • 66849107321 scopus 로고
    • The frequency of spina bifida occulta and rib anomalies in the parents of children with spina bifida aperta and meningocoele
    • Miller JR, Fraser FC, MacEwan DW, et al. 1962. The frequency of spina bifida occulta and rib anomalies in the parents of children with spina bifida aperta and meningocoele. Am J Hum Genet 14:245-248.
    • (1962) Am J Hum Genet , vol.14 , pp. 245-248
    • Miller, J.R.1    Fraser, F.C.2    MacEwan, D.W.3
  • 86
    • 70349774670 scopus 로고    scopus 로고
    • Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube
    • Miro X, Zhou X, Boretius S, et al. 2009. Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube. Dis Model Mech 2:412-418.
    • (2009) Dis Model Mech , vol.2 , pp. 412-418
    • Miro, X.1    Zhou, X.2    Boretius, S.3
  • 87
    • 70450225232 scopus 로고    scopus 로고
    • A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling
    • Misra K, Matise MP. 2010. A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling. Dev Biol 337:74-83.
    • (2010) Dev Biol , vol.337 , pp. 74-83
    • Misra, K.1    Matise, M.P.2
  • 88
    • 0030734016 scopus 로고    scopus 로고
    • Elevated rates of severe neural tube defects in a high-prevalence area in northern China
    • Moore CA, Li S, Li Z, et al. 1997. Elevated rates of severe neural tube defects in a high-prevalence area in northern China. Am J Med Genet 73:113-118.
    • (1997) Am J Med Genet , vol.73 , pp. 113-118
    • Moore, C.A.1    Li, S.2    Li, Z.3
  • 89
    • 0025863475 scopus 로고
    • Prevention of neural tube defects: Results of the Medical Research Council Vitamin Study
    • MRC Vitamin Study Research Group.
    • MRC Vitamin Study Research Group. 1991. Prevention of neural tube defects: results of the Medical Research Council Vitamin Study. Lancet 338:131-137.
    • (1991) Lancet , vol.338 , pp. 131-137
  • 90
    • 65449185484 scopus 로고    scopus 로고
    • Mouse H6 homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass
    • Munroe RJ, Prabhu V, Acland GM, et al. 2009. Mouse H6 homeobox 1 (Hmx1) mutations cause cranial abnormalities and reduced body mass. BMC Dev Biol 9:27.
    • (2009) BMC Dev Biol , vol.9 , pp. 27
    • Munroe, R.J.1    Prabhu, V.2    Acland, G.M.3
  • 91
    • 64249102010 scopus 로고    scopus 로고
    • Regulation of planar cell polarity by Smurf ubiquitin ligases
    • Narimatsu M, Bose R, Pye M, et al. 2009. Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell 137:295-307.
    • (2009) Cell , vol.137 , pp. 295-307
    • Narimatsu, M.1    Bose, R.2    Pye, M.3
  • 92
    • 0028244488 scopus 로고
    • Multifactorial inheritance of neural tube defects: Localization of the major gene and recognition of modifiers in ct mutant mice
    • Neumann PE, Frankel WN, Letts VA, et al. 1994. Multifactorial inheritance of neural tube defects: Localization of the major gene and recognition of modifiers in ct mutant mice. Nat Genet 6:357-362.
    • (1994) Nat Genet , vol.6 , pp. 357-362
    • Neumann, P.E.1    Frankel, W.N.2    Letts, V.A.3
  • 93
    • 77949860304 scopus 로고    scopus 로고
    • Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice
    • Okae H, Iwakura Y. 2010. Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice. Dev Dyn 239:1089-1101.
    • (2010) Dev Dyn , vol.239 , pp. 1089-1101
    • Okae, H.1    Iwakura, Y.2
  • 94
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • Okano M, Bell DW, Haber DA, et al. 1999. DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development. Cell 99:247-257.
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3
  • 95
    • 34548845571 scopus 로고    scopus 로고
    • Loss of the Atp2c1 secretory pathway Ca(21)-ATPase (SPCA1) in mice causes golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes
    • Okunade GW, Miller ML, Azhar M, et al. 2007. Loss of the Atp2c1 secretory pathway Ca(21)-ATPase (SPCA1) in mice causes golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes. J Biol Chem 282:26517-26527.
    • (2007) J Biol Chem , vol.282 , pp. 26517-26527
    • Okunade, G.W.1    Miller, M.L.2    Azhar, M.3
  • 96
    • 0026056574 scopus 로고
    • Diabetic environment and genetic predisposition as causes of congenital malformations in NOD mouse embryos
    • Otani H, Tanaka O, Tatewaki R, et al. 1991. Diabetic environment and genetic predisposition as causes of congenital malformations in NOD mouse embryos. Diabetes 40:1245-1250.
    • (1991) Diabetes , vol.40 , pp. 1245-1250
    • Otani, H.1    Tanaka, O.2    Tatewaki, R.3
  • 97
    • 0027999641 scopus 로고
    • Effect of pre-treatment with aspirin on alcohol-induced neural tube defects in the to mouse fetuses
    • Padmanabhan R, Wasfi IA, Craigmyle MB, et al. 1994. Effect of pre-treatment with aspirin on alcohol-induced neural tube defects in the TO mouse fetuses. Drug Alcohol Depend 36:175-186.
    • (1994) Drug Alcohol Depend , vol.36 , pp. 175-186
    • Padmanabhan, R.1    Wasfi, I.A.2    Craigmyle, M.B.3
  • 98
    • 33846900689 scopus 로고    scopus 로고
    • Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development
    • Pallerla SR, Pan Y, Zhang X, et al. 2007. Heparan sulfate Ndst1 gene function variably regulates multiple signaling pathways during mouse development. Dev Dyn 236:556-563.
    • (2007) Dev Dyn , vol.236 , pp. 556-563
    • Pallerla, S.R.1    Pan, Y.2    Zhang, X.3
  • 99
    • 65449156373 scopus 로고    scopus 로고
    • Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: Identification of Tulp3 as a novel negative regulator of the sonic hedgehog pathway
    • Patterson VL, Damrau C, Paudyal A, et al. 2009. Mouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the sonic hedgehog pathway. Hum Mol Genet 18:1719-1739.
    • (2009) Hum Mol Genet , vol.18 , pp. 1719-1739
    • Patterson, V.L.1    Damrau, C.2    Paudyal, A.3
  • 100
    • 0032884078 scopus 로고    scopus 로고
    • Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development
    • Piedrahita JA, Oetama B, Bennett GD, et al. 1999. Mice lacking the folic acid-binding protein Folbp1 are defective in early embryonic development. Nat Genet 23:228-232.
    • (1999) Nat Genet , vol.23 , pp. 228-232
    • Piedrahita, J.A.1    Oetama, B.2    Bennett, G.D.3
  • 101
    • 0037418193 scopus 로고    scopus 로고
    • Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission
    • Rakyan VK, Chong S, Champ ME, et al. 2003. Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission. Proc Natl Acad Sci U S A 100:2538-2543.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2538-2543
    • Rakyan, V.K.1    Chong, S.2    Champ, M.E.3
  • 102
    • 77949851049 scopus 로고    scopus 로고
    • Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure
    • Reid BS, Sargent TD, Williams T. 2010. Generation and characterization of a novel neural crest marker allele, Inka1-LacZ, reveals a role for Inka1 in mouse neural tube closure. Dev Dyn 239:1188-1196.
    • (2010) Dev Dyn , vol.239 , pp. 1188-1196
    • Reid, B.S.1    Sargent, T.D.2    Williams, T.3
  • 103
    • 77955641562 scopus 로고    scopus 로고
    • Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida and craniorachischisis
    • In press. (this issue)
    • Rocha P, Bleis W, Schrewe H. 2010. Mosaic expression of Med12 in female mice leads to exencephaly, spina bifida and craniorachischisis. Birth Defects Res A Clin Mol Teratol. In press. (this issue)
    • (2010) Birth Defects Res A Clin Mol Teratol
    • Rocha, P.1    Bleis, W.2    Schrewe, H.3
  • 104
    • 33749078802 scopus 로고    scopus 로고
    • Are encephaloceles neural tube defects?
    • Rowland CA, Correa A, Cragan JD, et al. 2006. Are encephaloceles neural tube defects? Pediatrics 118:916-923.
    • (2006) Pediatrics , vol.118 , pp. 916-923
    • Rowland, C.A.1    Correa, A.2    Cragan, J.D.3
  • 105
    • 39549107806 scopus 로고    scopus 로고
    • Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse
    • Satoh W, Matsuyama M, Takemura H, et al. 2008. Sfrp1, Sfrp2, and Sfrp5 regulate the Wnt/beta-catenin and the planar cell polarity pathways during early trunk formation in mouse. Genesis 46:92-103.
    • (2008) Genesis , vol.46 , pp. 92-103
    • Satoh, W.1    Matsuyama, M.2    Takemura, H.3
  • 106
    • 28044443871 scopus 로고    scopus 로고
    • Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor
    • Sawada A, Nishizaki Y, Sato H, et al. 2005. Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor. Development 132:4719-4729.
    • (2005) Development , vol.132 , pp. 4719-4729
    • Sawada, A.1    Nishizaki, Y.2    Sato, H.3
  • 107
    • 50649111380 scopus 로고    scopus 로고
    • Gene targeting of CK2 catalytic subunits
    • Seldin DC, Lou DY, Toselli P, et al. 2008. Gene targeting of CK2 catalytic subunits. Mol Cell Biochem 316:141-147.
    • (2008) Mol Cell Biochem , vol.316 , pp. 141-147
    • Seldin, D.C.1    Lou, D.Y.2    Toselli, P.3
  • 108
    • 0029057083 scopus 로고
    • Sex, neural tube defects, and multisite closure of the human neural tube
    • Seller MJ. 1995. Sex, neural tube defects, and multisite closure of the human neural tube. Am J Med Genet 58:332-336.
    • (1995) Am J Med Genet , vol.58 , pp. 332-336
    • Seller, M.J.1
  • 109
    • 0028247567 scopus 로고
    • Vitamins, folic acid and the cause and prevention of neural tube defects
    • Seller MJ. 1994. Vitamins, folic acid and the cause and prevention of neural tube defects. Ciba Found Symp 181:161-73.
    • (1994) Ciba Found Symp , vol.181 , pp. 161-173
    • Seller, M.J.1
  • 110
    • 0019833128 scopus 로고
    • The curly-tail mouse: An experimental model for human neural tube defects
    • Seller MJ, Adinolfi M. 1981. The curly-tail mouse: an experimental model for human neural tube defects. Life Sci 29:1607-1615.
    • (1981) Life Sci , vol.29 , pp. 1607-1615
    • Seller, M.J.1    Adinolfi, M.2
  • 111
    • 67349165028 scopus 로고    scopus 로고
    • Trafficking, development and hedgehog
    • Simpson F, Kerr MC, Wicking C., et al. 2009. Trafficking, development and hedgehog. Mech Dev 126:279-288.
    • (2009) Mech Dev , vol.126 , pp. 279-288
    • Simpson, F.1    Kerr, M.C.2    Wicking, C.3
  • 112
    • 51349156652 scopus 로고    scopus 로고
    • Influences of reduced expression of maternal bone morphogenetic protein 2 on mouse embryonic development
    • Singh AP, Castranio T, Scott G, et al. 2008. Influences of reduced expression of maternal bone morphogenetic protein 2 on mouse embryonic development. Sex Dev 2:134-141.
    • (2008) Sex Dev , vol.2 , pp. 134-141
    • Singh, A.P.1    Castranio, T.2    Scott, G.3
  • 113
    • 4143082484 scopus 로고    scopus 로고
    • Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation
    • Spiegelstein O, Mitchell LE, Merriweather MY, et al. 2004. Embryonic development of folate binding protein-1 (Folbp1) knockout mice: Effects of the chemical form, dose, and timing of maternal folate supplementation. Dev Dyn 231:221-231.
    • (2004) Dev Dyn , vol.231 , pp. 221-231
    • Spiegelstein, O.1    Mitchell, L.E.2    Merriweather, M.Y.3
  • 114
    • 55449091272 scopus 로고    scopus 로고
    • Accelerated embryonic development associated with increased risk of neural tube defects induced by maternal diet in offspring of SELH/Bc mice
    • Stoate KL, Harris MJ, Juriloff DM., et al. 2008. Accelerated embryonic development associated with increased risk of neural tube defects induced by maternal diet in offspring of SELH/Bc mice. Birth Defects Res A Clin Mol Teratol 82:720-727.
    • (2008) Birth Defects Res A Clin Mol Teratol , vol.82 , pp. 720-727
    • Stoate, K.L.1    Harris, M.J.2    Juriloff, D.M.3
  • 115
    • 0032585635 scopus 로고    scopus 로고
    • Rac1 is required for the formation of three germ layers during gastrulation
    • Sugihara K, Nakatsuji N, Nakamura K, et al. 1998. Rac1 is required for the formation of three germ layers during gastrulation. Oncogene 17:3427-3433.
    • (1998) Oncogene , vol.17 , pp. 3427-3433
    • Sugihara, K.1    Nakatsuji, N.2    Nakamura, K.3
  • 116
    • 69049092775 scopus 로고    scopus 로고
    • Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice
    • Szabo R, Hobson JP, Christoph K, et al. 2009. Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice. Development 136:2653-2663.
    • (2009) Development , vol.136 , pp. 2653-2663
    • Szabo, R.1    Hobson, J.P.2    Christoph, K.3
  • 117
    • 0348107340 scopus 로고    scopus 로고
    • Inositol- And folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3
    • Ting SB, Wilanowski T, Auden A, et al. 2003. Inositol- and folate-resistant neural tube defects in mice lacking the epithelial-specific factor Grhl-3. Nat Med 9:1513-1519.
    • (2003) Nat Med , vol.9 , pp. 1513-1519
    • Ting, S.B.1    Wilanowski, T.2    Auden, A.3
  • 118
    • 42149191189 scopus 로고    scopus 로고
    • Genetic interaction between members of the Vangl family causes neural tube defects in mice
    • Torban E, Patenaude AM, Leclerc S, et al. 2008. Genetic interaction between members of the Vangl family causes neural tube defects in mice. Proc Natl Acad Sci U S A 105:3449-3454.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 3449-3454
    • Torban, E.1    Patenaude, A.M.2    Leclerc, S.3
  • 119
    • 0026781876 scopus 로고
    • Effects of H-2 on neural tube defects in congenic mice
    • Tyan ML. 1992. Effects of H-2 on neural tube defects in congenic mice. Proc Soc Exp Biol Med 200:487-489.
    • (1992) Proc Soc Exp Biol Med , vol.200 , pp. 487-489
    • Tyan, M.L.1
  • 120
    • 77955629374 scopus 로고    scopus 로고
    • University of California Santa Cruz Genome Browser. Available at: Accessed February 2010
    • University of California Santa Cruz Genome Browser. 2007. Mouse, July 2007 freeze. Available at: http://genome.ucsc.edu. Accessed February 2010.
    • (2007) Mouse, July 2007 Freeze
  • 121
    • 33745466418 scopus 로고    scopus 로고
    • Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development
    • van Meeteren LA, Ruurs P, Stortelers C, et al. 2006. Autotaxin, a secreted lysophospholipase D, is essential for blood vessel formation during development. Mol Cell Biol 26:5015-5022.
    • (2006) Mol Cell Biol , vol.26 , pp. 5015-5022
    • Van Meeteren, L.A.1    Ruurs, P.2    Stortelers, C.3
  • 122
    • 0035041246 scopus 로고    scopus 로고
    • Curly tail: A 50-year history of the mouse spina bifida model
    • Berl
    • van Straaten HW, Copp AJ. 2001. Curly tail: a 50-year history of the mouse spina bifida model. Anat Embryol (Berl) 203:225-237.
    • (2001) Anat Embryol , vol.203 , pp. 225-237
    • Van Straaten, H.W.1    Copp, A.J.2
  • 123
    • 0030776825 scopus 로고    scopus 로고
    • Two dominant mutations in the mouse Fused gene are the result of transposon insertions
    • Vasicek TJ, Zeng L, Guan XJ, et al. 1997. Two dominant mutations in the mouse Fused gene are the result of transposon insertions. Genetics 147:777-786.
    • (1997) Genetics , vol.147 , pp. 777-786
    • Vasicek, T.J.1    Zeng, L.2    Guan, X.J.3
  • 124
    • 8344261349 scopus 로고    scopus 로고
    • Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis
    • Vega RB, Matsuda K, Oh J, et al. 2004. Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell 119:555-566.
    • (2004) Cell , vol.119 , pp. 555-566
    • Vega, R.B.1    Matsuda, K.2    Oh, J.3
  • 125
    • 0027398807 scopus 로고
    • New Zealand White mice: An experimental model of exencephaly
    • Vogelweid CM, Vogt DW, Besch-Williford CL, et al. 1993. New Zealand White mice: an experimental model of exencephaly. Lab Anim Sci 43:58-60.
    • (1993) Lab Anim Sci , vol.43 , pp. 58-60
    • Vogelweid, C.M.1    Vogt, D.W.2    Besch-Williford, C.L.3
  • 126
    • 35649014879 scopus 로고    scopus 로고
    • Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism
    • Wakefield L, Cornish V, Long H, et al. 2007. Deletion of a xenobiotic metabolizing gene in mice affects folate metabolism. Biochem Biophys Res Commun 364:556-560.
    • (2007) Biochem Biophys Res Commun , vol.364 , pp. 556-560
    • Wakefield, L.1    Cornish, V.2    Long, H.3
  • 127
    • 38049138816 scopus 로고    scopus 로고
    • Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: A potential marker for the developing neuroendocrine system
    • Wakefield L, Cornish V, Long H, et al. 2008. Mouse arylamine N-acetyltransferase 2 (Nat2) expression during embryogenesis: a potential marker for the developing neuroendocrine system. Biomarkers 13:106-118.
    • (2008) Biomarkers , vol.13 , pp. 106-118
    • Wakefield, L.1    Cornish, V.2    Long, H.3
  • 128
    • 70350672572 scopus 로고    scopus 로고
    • Mice defective in Trpm6 show embryonic mortality and neural tube defects
    • Walder RY, Yang B, Stokes JB, et al. 2009. Mice defective in Trpm6 show embryonic mortality and neural tube defects. Hum Mol Genet 18:4367-4375.
    • (2009) Hum Mol Genet , vol.18 , pp. 4367-4375
    • Walder, R.Y.1    Yang, B.2    Stokes, J.B.3
  • 129
    • 33744547152 scopus 로고    scopus 로고
    • Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation
    • Wang J, Hamblet NS, Mark S, et al. 2006. Dishevelled genes mediate a conserved mammalian PCP pathway to regulate convergent extension during neurulation. Development 133:1767-1778.
    • (2006) Development , vol.133 , pp. 1767-1778
    • Wang, J.1    Hamblet, N.S.2    Mark, S.3
  • 130
    • 34547443913 scopus 로고    scopus 로고
    • PIP5KI gamma is required for cardiovascular and neuronal development
    • Wang Y, Lian L, Golden JA, et al. 2007. PIP5KI gamma is required for cardiovascular and neuronal development. Proc Natl Acad Sci U S A 104:11748-11753.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 11748-11753
    • Wang, Y.1    Lian, L.2    Golden, J.A.3
  • 131
    • 0043093697 scopus 로고    scopus 로고
    • Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
    • Waterland RA, Jirtle RL. 2003. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 23:5293-5300.
    • (2003) Mol Cell Biol , vol.23 , pp. 5293-5300
    • Waterland, R.A.1    Jirtle, R.L.2
  • 132
    • 74049156323 scopus 로고    scopus 로고
    • Neural stem cell self-renewal requires the Mrj co-chaperone
    • Watson ED, Mattar P, Schuurmans C, et al. 2009. Neural stem cell self-renewal requires the Mrj co-chaperone. Dev Dyn 238:2564-2574.
    • (2009) Dev Dyn , vol.238 , pp. 2564-2574
    • Watson, E.D.1    Mattar, P.2    Schuurmans, C.3
  • 133
    • 70449353527 scopus 로고    scopus 로고
    • A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and hedgehog signaling
    • Weatherbee SD, Niswander LA, Anderson KV., et al. 2009. A mouse model for Meckel syndrome reveals Mks1 is required for ciliogenesis and hedgehog signaling. Hum Mol Genet 18:4565-4575.
    • (2009) Hum Mol Genet , vol.18 , pp. 4565-4575
    • Weatherbee, S.D.1    Niswander, L.A.2    Anderson, K.V.3
  • 134
    • 67649858788 scopus 로고    scopus 로고
    • Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase
    • Wilson MP, Hugge C, Bielinska M, et al. 2009. Neural tube defects in mice with reduced levels of inositol 1,3,4-trisphosphate 5/6-kinase. Proc Natl Acad Sci U S A 106:9831-9835.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9831-9835
    • Wilson, M.P.1    Hugge, C.2    Bielinska, M.3
  • 135
    • 33745176611 scopus 로고    scopus 로고
    • Spontaneous neural tube defects in Splotch mice supplemented with selected micronutrients
    • Wlodarczyk BJ, Tang LS, Triplett A, et al. 2006. Spontaneous neural tube defects in Splotch mice supplemented with selected micronutrients. Toxicol Appl Pharmacol 213:55-63.
    • (2006) Toxicol Appl Pharmacol , vol.213 , pp. 55-63
    • Wlodarczyk, B.J.1    Tang, L.S.2    Triplett, A.3
  • 136
    • 38049048040 scopus 로고    scopus 로고
    • Targeted disruption of Mib2 causes exencephaly with a variable penetrance
    • Wu JI, Rajendra R, Barsi JC, et al. 2007. Targeted disruption of Mib2 causes exencephaly with a variable penetrance. Genesis 45:722-727.
    • (2007) Genesis , vol.45 , pp. 722-727
    • Wu, J.I.1    Rajendra, R.2    Barsi, J.C.3
  • 137
    • 0016758619 scopus 로고
    • Congenital vertebral anomalies: Aetiology and relationship to spina bifida cystica
    • Wynne-Davies R. 1975. Congenital vertebral anomalies: aetiology and relationship to spina bifida cystica. J Med Genet 12:280-288.
    • (1975) J Med Genet , vol.12 , pp. 280-288
    • Wynne-Davies, R.1
  • 138
    • 0033623238 scopus 로고    scopus 로고
    • Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development
    • Xu W, Edmondson DG, Evrard YA, et al. 2000. Loss of Gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet 26:229-232.
    • (2000) Nat Genet , vol.26 , pp. 229-232
    • Xu, W.1    Edmondson, D.G.2    Evrard, Y.A.3
  • 139
    • 46049083566 scopus 로고    scopus 로고
    • Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex
    • Yamamoto S, Nishimura O, Misaki K, et al. 2008. Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell 15:23-36.
    • (2008) Dev Cell , vol.15 , pp. 23-36
    • Yamamoto, S.1    Nishimura, O.2    Misaki, K.3
  • 140
    • 17644445419 scopus 로고    scopus 로고
    • Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300
    • Yao TP, Oh SP, Fuchs M, et al. 1998. Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell 93:361-372.
    • (1998) Cell , vol.93 , pp. 361-372
    • Yao, T.P.1    Oh, S.P.2    Fuchs, M.3
  • 141
    • 34848895721 scopus 로고    scopus 로고
    • Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling
    • Ybot-Gonzalez P, Gaston-Massuet C, Girdler G, et al. 2007. Neural plate morphogenesis during mouse neurulation is regulated by antagonism of Bmp signalling. Development 134:3203-3211.
    • (2007) Development , vol.134 , pp. 3203-3211
    • Ybot-Gonzalez, P.1    Gaston-Massuet, C.2    Girdler, G.3
  • 142
    • 77149146791 scopus 로고    scopus 로고
    • PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals
    • Zeng H, Hoover AN, Liu A, et al. 2010. PCP effector gene Inturned is an important regulator of cilia formation and embryonic development in mammals. Dev Biol 339:418-428.
    • (2010) Dev Biol , vol.339 , pp. 418-428
    • Zeng, H.1    Hoover, A.N.2    Liu, A.3
  • 143
    • 0029946542 scopus 로고    scopus 로고
    • Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene
    • Zhao Q, Behringer RR, de Crombrugghe B, et al. 1996. Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene. Nat Genet 13:275-283.
    • (1996) Nat Genet , vol.13 , pp. 275-283
    • Zhao, Q.1    Behringer, R.R.2    De Crombrugghe, B.3
  • 144
    • 33750959415 scopus 로고    scopus 로고
    • Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics
    • Zheng B, Tang T, Tang N, et al. 2006. Essential role of RGS-PX1/sorting nexin 13 in mouse development and regulation of endocytosis dynamics. Proc Natl Acad Sci U S A 103:16776-16781.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 16776-16781
    • Zheng, B.1    Tang, T.2    Tang, N.3
  • 145
    • 0037341890 scopus 로고    scopus 로고
    • Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects
    • Zhu H, Wicker NJ, Shaw GM, et al. 2003. Homocysteine remethylation enzyme polymorphisms and increased risks for neural tube defects. Mol Genet Metab 78:216-221.
    • (2003) Mol Genet Metab , vol.78 , pp. 216-221
    • Zhu, H.1    Wicker, N.J.2    Shaw, G.M.3
  • 146
    • 34249671135 scopus 로고    scopus 로고
    • The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure
    • Zohn IE, Anderson KV, Niswander L, et al. 2007a. The Hectd1 ubiquitin ligase is required for development of the head mesenchyme and neural tube closure. Dev Biol 306:208-221.
    • (2007) Dev Biol , vol.306 , pp. 208-221
    • Zohn, I.E.1    Anderson, K.V.2    Niswander, L.3
  • 147
    • 34248343093 scopus 로고    scopus 로고
    • The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease
    • Zohn IE, De Domenico I, Pollock A, et al. 2007b. The flatiron mutation in mouse ferroportin acts as a dominant negative to cause ferroportin disease. Blood 109:4174-4180.
    • (2007) Blood , vol.109 , pp. 4174-4180
    • Zohn, I.E.1    De Domenico, I.2    Pollock, A.3
  • 148
    • 1642474027 scopus 로고    scopus 로고
    • Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis
    • Zoltewicz JS, Stewart NJ, Leung R, et al. 2004. Atrophin 2 recruits histone deacetylase and is required for the function of multiple signaling centers during mouse embryogenesis. Development 131:3-14.
    • (2004) Development , vol.131 , pp. 3-14
    • Zoltewicz, J.S.1    Stewart, N.J.2    Leung, R.3
  • 149
    • 34249700735 scopus 로고    scopus 로고
    • Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure
    • Zwerts F, Lupu F, De Vriese A, et al. 2007. Lack of endothelial cell survivin causes embryonic defects in angiogenesis, cardiogenesis, and neural tube closure. Blood 109:4742-4752.
    • (2007) Blood , vol.109 , pp. 4742-4752
    • Zwerts, F.1    Lupu, F.2    De Vriese, A.3


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