메뉴 건너뛰기




Volumn 11, Issue 2, 2013, Pages 209-217

ACE2-ang-(1-7)-mas axis in brain: A potential target for prevention and treatment of ischemic stroke

Author keywords

Angiotensin (1 7); Neuroprotection; Oxidative stress; Renin angiotensin system; Stroke

Indexed keywords

ACE2 ANGIOTENSIN (1-7) MAS AXIS; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN CONVERTING ENZYME 2; APOLIPOPROTEIN E; BRADYKININ; BRADYKININ B2 RECEPTOR; CYCLINE; CYCLOOXYGENASE 2; DIPEPTIDYL CARBOXYPEPTIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MEMBRANE METALLOENDOPEPTIDASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; MONOCYTE CHEMOTACTIC PROTEIN 1; N ETHYLCARBAMOYL 3 [4 (5 FORMYL 4 METHOXY 2 PHENYL 1 IMIDAZOLYLMETHYL) PHENYL] 5 ISOBUTYL 2 THIOPHENESULFONAMIDE; N ETHYLCARBAMOYL 3 [4 (5 FORMYL 4 METHOXY 2 PHENYL 1 IMIDAZOLYLMETHYL)PHENYL] 5 ISOBUTYL 2 THIOPHENESULFONAMIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXIDIZED LOW DENSITY LIPOPROTEIN RECEPTOR 1; PROSTACYCLIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 84876743592     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X11311020007     Document Type: Article
Times cited : (101)

References (96)
  • 1
    • 84856605923 scopus 로고    scopus 로고
    • Epidemiology and prevention of stroke: A worldwide perspective
    • Kuklina, E.V.; Tong, X.; George, M.G.; Bansil, P. Epidemiology and prevention of stroke: a worldwide perspective. Expert. Rev. Neurother., 2012, 12(2), 199-208.
    • (2012) Expert. Rev. Neurother , vol.12 , Issue.2 , pp. 199-208
    • Kuklina, E.V.1    Tong, X.2    George, M.G.3    Bansil, P.4
  • 4
    • 77951183011 scopus 로고    scopus 로고
    • Angiotensinconverting enzyme 2: A new target for neurogenic hypertension
    • Feng, Y.; Xia, H.; Santos, R.A.; Speth, R.; Lazartigues, E. Angiotensinconverting enzyme 2: a new target for neurogenic hypertension. Exp. Physiol., 2010, 95(5), 601-606.
    • (2010) Exp. Physiol , vol.95 , Issue.5 , pp. 601-606
    • Feng, Y.1    Xia, H.2    Santos, R.A.3    Speth, R.4    Lazartigues, E.5
  • 6
    • 77955175630 scopus 로고    scopus 로고
    • Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice
    • Tesanovic, S.; Vinh, A.; Gaspari, T.A.; Casley, D.; Widdop, R.E. Vasoprotective and atheroprotective effects of angiotensin (1-7) in apolipoprotein E-deficient mice. Arterioscler. Thromb. Vasc. Biol., 2010, 30, 1606-1613.
    • (2010) Arterioscler. Thromb. Vasc. Biol , vol.30 , pp. 1606-1613
    • Tesanovic, S.1    Vinh, A.2    Gaspari, T.A.3    Casley, D.4    Widdop, R.E.5
  • 10
    • 84868667825 scopus 로고    scopus 로고
    • Suppressing inflammation by inhibiting NF-κB pathway contributes to the neuroprotection of angiotensin-(1-7) in rats with permanent cerebral ischemia
    • doi: 10.1111/j.1476- 5381.2012.02105.x
    • Jiang, T.; Gao, L.; Gun, J.; Lu, J.; Wang, Y.; Zhang, Y. Suppressing inflammation by inhibiting NF-κB pathway contributes to the neuroprotection of angiotensin-(1-7) in rats with permanent cerebral ischemia. Br. J. Pharmacol., 2012. doi: 10.1111/j.1476- 5381.2012.02105.x.
    • (2012) Br. J. Pharmacol
    • Jiang, T.1    Gao, L.2    Gun, J.3    Lu, J.4    Wang, Y.5    Zhang, Y.6
  • 12
    • 79751504524 scopus 로고    scopus 로고
    • ACE2-angiotensin-(1-7)-Mas axis and oxidative stress in cardiovascular disease
    • Rabelo, L.A.; Alenina, N.; Bader, M. ACE2-angiotensin-(1-7)-Mas axis and oxidative stress in cardiovascular disease. Hypertens. Res., 2011, 34, 154-160.
    • (2011) Hypertens. Res , vol.34 , pp. 154-160
    • Rabelo, L.A.1    Alenina, N.2    Bader, M.3
  • 13
    • 0038606899 scopus 로고    scopus 로고
    • Brain rennin-angiotensin system dysfunction in hypertension: Recent advances and perspectives
    • Veerasingham, S.J.; Raizada, M.K. Brain rennin-angiotensin system dysfunction in hypertension: recent advances and perspectives. Br. J. Pharmacol., 2003, 139(2), 191-202.
    • (2003) Br. J. Pharmacol , vol.139 , Issue.2 , pp. 191-202
    • Veerasingham, S.J.1    Raizada, M.K.2
  • 15
    • 83155181573 scopus 로고    scopus 로고
    • Role of T lymphocytes in angiotensin II-mediated microvascular thrombosis
    • Senchenkova, E.Y.; Russell, J.; Kurmaeva, E.; Ostanin, D.; Granger, D.N. Role of T lymphocytes in angiotensin II-mediated microvascular thrombosis. Hypertension, 2011, 58(5), 959-965.
    • (2011) Hypertension , vol.58 , Issue.5 , pp. 959-965
    • Senchenkova, E.Y.1    Russell, J.2    Kurmaeva, E.3    Ostanin, D.4    Granger, D.N.5
  • 16
    • 0034129997 scopus 로고    scopus 로고
    • Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice
    • Daugherty, A.; Manning, M.W.; Cassis, L.A. Angiotensin II promotes atherosclerotic lesions and aneurysms in apolipoprotein E-deficient mice. J. Clin. Invest., 2000, 105(11), 1605-1612.
    • (2000) J. Clin. Invest , vol.105 , Issue.11 , pp. 1605-1612
    • Daugherty, A.1    Manning, M.W.2    Cassis, L.A.3
  • 17
    • 84864242097 scopus 로고    scopus 로고
    • Role of Nox Isoforms in Angiotensin II-Induced Oxidative Stress and Endothelial Dysfunction in Brain
    • Chrissobolis, S.; Banfi, B.; Sobey, C.G.; Faraci, F.M. Role of Nox Isoforms in Angiotensin II-Induced Oxidative Stress and Endothelial Dysfunction in Brain. J. Appl. Physiol., 2012, 113(2), 184-191.
    • (2012) J. Appl. Physiol , vol.113 , Issue.2 , pp. 184-191
    • Chrissobolis, S.1    Banfi, B.2    Sobey, C.G.3    Faraci, F.M.4
  • 18
    • 80054110392 scopus 로고    scopus 로고
    • Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia
    • Fu, H.; Hosomi, N.; Pelisch, N. Therapeutic effects of postischemic treatment with hypotensive doses of an angiotensin II receptor blocker on transient focal cerebral ischemia. J. Hypertens., 2011, 29(11), 2210-2219
    • (2011) J. Hypertens , vol.29 , Issue.11 , pp. 2210-2219
    • Fu, H.1    Hosomi, N.2    Pelisch, N.3
  • 19
    • 79959736871 scopus 로고    scopus 로고
    • Role of angiotensin II receptor subtype activation in cognitive function and ischaemic brain damage
    • Horiuchi, M.; Mogi, M. Role of angiotensin II receptor subtype activation in cognitive function and ischaemic brain damage. Br. J. Pharmacol., 2011, 163(6), 1122-1130.
    • (2011) Br. J. Pharmacol , vol.163 , Issue.6 , pp. 1122-1130
    • Horiuchi, M.1    Mogi, M.2
  • 20
    • 0034721906 scopus 로고    scopus 로고
    • A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase
    • Tipnis, S.R.; Hooper, N.M.; Hyde, R.; Karran, E.; Christie, G.; Turner, A.J. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J. Biol. Chem., 2000, 275(43), 33238-33243.
    • (2000) J. Biol. Chem , vol.275 , Issue.43 , pp. 33238-33243
    • Tipnis, S.R.1    Hooper, N.M.2    Hyde, R.3    Karran, E.4    Christie, G.5    Turner, A.J.6
  • 22
    • 33644861536 scopus 로고    scopus 로고
    • Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes
    • Gallagher, P.E.; Chappell, M.C.; Ferrario, C.M.; Tallant, E.A. Distinct roles for ANG II and ANG-(1-7) in the regulation of angiotensin-converting enzyme 2 in rat astrocytes. Am. J. Physiol. Cell. Physiol., 2006, 290(2), C420-C426.
    • (2006) Am. J. Physiol. Cell. Physiol , vol.290 , Issue.2
    • Gallagher, P.E.1    Chappell, M.C.2    Ferrario, C.M.3    Tallant, E.A.4
  • 23
    • 2642539225 scopus 로고    scopus 로고
    • Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis
    • Hamming, I., Timens, W., Bulthuis, M.L.C.; Lely, A.T.; Navis, G.J.; van Goor, H. Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis. J. Pathol., 2004, 203(2), 631-637.
    • (2004) J. Pathol , vol.203 , Issue.2 , pp. 631-637
    • Hamming, I.1    Timens, W.2    Bulthuis, M.L.C.3    Lely, A.T.4    Navis, G.J.5    van Goor, H.6
  • 26
    • 77954772667 scopus 로고    scopus 로고
    • Astroglia are a possible cellular substrate of angiotensin (1-7) effects in the rostral ventrolateral medulla
    • Guo, F.; Liu, B.; Tang, F.; Lane, S.; Souslova, E.A.; Chudakov, D.M.; Paton, J.F.; Kasparov, S. Astroglia are a possible cellular substrate of angiotensin (1-7) effects in the rostral ventrolateral medulla. Cardiovasc. Res., 2010, 87(3), 578-584.
    • (2010) Cardiovasc. Res , vol.87 , Issue.3 , pp. 578-584
    • Guo, F.1    Liu, B.2    Tang, F.3    Lane, S.4    Souslova, E.A.5    Chudakov, D.M.6    Paton, J.F.7    Kasparov, S.8
  • 27
    • 0030896125 scopus 로고    scopus 로고
    • Selective expression of c-mas proto-oncogene in rat cerebral endothelial cells
    • Kumar, M.; Grammas, P.; Giacomelli, F.; Wiener, J. Selective expression of c-mas proto-oncogene in rat cerebral endothelial cells. Neuroreport,1996, 8(1), 93-96.
    • (1996) Neuroreport , vol.8 , Issue.1 , pp. 93-96
    • Kumar, M.1    Grammas, P.2    Giacomelli, F.3    Wiener, J.4
  • 28
    • 0023746492 scopus 로고
    • Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain
    • Young, D.; O'Neill, K.; Jessell, T.; Wigler, M. Characterization of the rat mas oncogene and its high-level expression in the hippocampus and cerebral cortex of rat brain. Proc. Natl. Acad. Sci. U.S.A., 1988, 85(14), 5339-5342.
    • (1988) Proc. Natl. Acad. Sci. U.S.A , vol.85 , Issue.14 , pp. 5339-5342
    • Young, D.1    O'Neill, K.2    Jessell, T.3    Wigler, M.4
  • 31
    • 0024445978 scopus 로고
    • Identification of angiotensin-(1-7) in rat brain. Evidence for differential processing of angiotensin peptides
    • Chappell, M.C.; Brosnihan, K.B.; Diz, D.I.; Ferrario, C.M. Identification of angiotensin-(1-7) in rat brain. Evidence for differential processing of angiotensin peptides. J. Biol. Chem., 1989, 264(28), 16518-16523.
    • (1989) J. Biol. Chem , vol.264 , Issue.28 , pp. 16518-16523
    • Chappell, M.C.1    Brosnihan, K.B.2    Diz, D.I.3    Ferrario, C.M.4
  • 32
    • 34447126601 scopus 로고    scopus 로고
    • Primary role of angiotensin converting enzyme 2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats
    • Trask, A.J.; Averill, D.B.; Ganten, D.; Chappell, M.C.; Ferrario, C.M. Primary role of angiotensin converting enzyme 2 in cardiac production of angiotensin-(1-7) in transgenic Ren-2 hypertensive rats. Am. J. Physiol. Heart. Circ. Physiol., 2007, 292(6), H3019-H3024.
    • (2007) Am. J. Physiol. Heart. Circ. Physiol , vol.292 , Issue.6
    • Trask, A.J.1    Averill, D.B.2    Ganten, D.3    Chappell, M.C.4    Ferrario, C.M.5
  • 33
    • 0027406861 scopus 로고
    • A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: Angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11
    • Welches, W.R.; Brosnihan, K.B.; Ferrario, C.M. A comparison of the properties and enzymatic activities of three angiotensin processing enzymes: angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11. Life Sci., 1993, 52, 1461-1480.
    • (1993) Life Sci , vol.52 , pp. 1461-1480
    • Welches, W.R.1    Brosnihan, K.B.2    Ferrario, C.M.3
  • 34
    • 0031600505 scopus 로고    scopus 로고
    • Metabolism of angiotensin-(1-7) by angiotensin-converting enzyme
    • Chappell, M.C.; Pirro, N.T.; Sykes, A.; Ferrario, C.M. Metabolism of angiotensin-(1-7) by angiotensin-converting enzyme. Hypertension, 1998, 31(1 Pt 2), 362-367.
    • (1998) Hypertension , vol.31 , Issue.1 PART 2 , pp. 362-367
    • Chappell, M.C.1    Pirro, N.T.2    Sykes, A.3    Ferrario, C.M.4
  • 36
    • 80053198167 scopus 로고    scopus 로고
    • From hypertension to stroke: Mechanisms and potential prevention strategies
    • Yu, J.G.; Zhou, R.R.; Cai, G.J. From hypertension to stroke: mechanisms and potential prevention strategies. CNS Neurosci. Ther., 2011, 17(5), 577-584.
    • (2011) CNS Neurosci. Ther , vol.17 , Issue.5 , pp. 577-584
    • Yu, J.G.1    Zhou, R.R.2    Cai, G.J.3
  • 37
    • 0036794272 scopus 로고    scopus 로고
    • Beyond blood pressure: The endothelium and atherosclerosis progression
    • Schiffrin, E.L. Beyond blood pressure: the endothelium and atherosclerosis progression. Am. J. Hypertens., 2002, 15, 115S-122S.
    • (2002) Am. J. Hypertens , vol.15
    • Schiffrin, E.L.1
  • 38
    • 34548499309 scopus 로고    scopus 로고
    • Primary and secondary prevention of stroke by antihypertensive treatment in clinical trials
    • Grassi, G.; Arenare, F.; Trevano, F.Q.; Dell'Oro, R.; Mancia, A.G. Primary and secondary prevention of stroke by antihypertensive treatment in clinical trials. Curr. Hypertens. Rep., 2007, 9(4), 299-304.
    • (2007) Curr. Hypertens. Rep , vol.9 , Issue.4 , pp. 299-304
    • Grassi, G.1    Arenare, F.2    Trevano, F.Q.3    Dell'Oro, R.4    Mancia, A.G.5
  • 39
    • 42649141198 scopus 로고    scopus 로고
    • Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats
    • Diz, D.I.; Garcia-Espinosa, M.A.; Gegick, S.; Tommasi, E.N.; Ferrario, C.M.; Ann Tallant, E.; Chappell, M.C.; Gallagher, P.E. Injections of angiotensin-converting enzyme 2 inhibitor MLN4760 into nucleus tractus solitarii reduce baroreceptor reflex sensitivity for heart rate control in rats. Exp. Physiol., 2008, 93(5), 694-700.
    • (2008) Exp. Physiol , vol.93 , Issue.5 , pp. 694-700
    • Diz, D.I.1    Garcia-Espinosa, M.A.2    Gegick, S.3    Tommasi, E.N.4    Ferrario, C.M.5    Ann, T.E.6    Chappell, M.C.7    Gallagher, P.E.8
  • 40
    • 34047193877 scopus 로고    scopus 로고
    • Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats
    • Yamazato, M.; Yamazato, Y.; Sun, C.; Diez-Freire, C.; Raizada, M.K. Overexpression of angiotensin-converting enzyme 2 in the rostral ventrolateral medulla causes long-term decrease in blood pressure in the spontaneously hypertensive rats. Hypertension, 2007, 49(4), 926-931.
    • (2007) Hypertension , vol.49 , Issue.4 , pp. 926-931
    • Yamazato, M.1    Yamazato, Y.2    Sun, C.3    Diez-Freire, C.4    Raizada, M.K.5
  • 41
    • 59849099636 scopus 로고    scopus 로고
    • Angiotensin II type 1 receptor-mediated reduction of angiotensinconverting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice
    • Xia, H.; Feng, Y.; Obr, T.D.; Hickman, P.J.; Lazartigues, E. Angiotensin II type 1 receptor-mediated reduction of angiotensinconverting enzyme 2 activity in the brain impairs baroreflex function in hypertensive mice. Hypertension, 2009, 53(2), 210-216.
    • (2009) Hypertension , vol.53 , Issue.2 , pp. 210-216
    • Xia, H.1    Feng, Y.2    Obr, T.D.3    Hickman, P.J.4    Lazartigues, E.5
  • 42
    • 76349095332 scopus 로고    scopus 로고
    • Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension
    • Feng Y, Xia H, Cai Y, Halabi, C.M., Becker, L.K., Santos, R.A., Speth, R.C., Sigmund, C.D., Lazartigues, E. Brain-selective overexpression of human Angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circ. Res., 2010,106(2), 373-382.
    • (2010) Circ. Res , vol.106 , Issue.2 , pp. 373-382
    • Feng, Y.1    Xia, H.2    Cai, Y.3    Halabi, C.M.4    Becker, L.K.5    Santos, R.A.6    Speth, R.C.7    Sigmund, C.D.8    Lazartigues, E.9
  • 43
    • 81055133082 scopus 로고    scopus 로고
    • ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension
    • Sriramula, S.; Cardinale, J.P.; Lazartigues, E.; Francis, J. ACE2 overexpression in the paraventricular nucleus attenuates angiotensin II-induced hypertension. Cardiovasc. Res., 2011, 92(3), 401-408.
    • (2011) Cardiovasc. Res , vol.92 , Issue.3 , pp. 401-408
    • Sriramula, S.1    Cardinale, J.P.2    Lazartigues, E.3    Francis, J.4
  • 44
    • 0033668722 scopus 로고    scopus 로고
    • Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats
    • Chaves, G.Z.; Caligiorne, S.M.; Santos, R.A.; Khosla, M.C.; Campagnole-Santos, M.J. Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats. J. Hypertens., 2000, 18(12), 1841-1848.
    • (2000) J. Hypertens , vol.18 , Issue.12 , pp. 1841-1848
    • Chaves, G.Z.1    Caligiorne, S.M.2    Santos, R.A.3    Khosla, M.C.4    Campagnole-Santos, M.J.5
  • 45
    • 38349130187 scopus 로고    scopus 로고
    • Involvement of angiotensin-(1-7) in the hypothalamic hypotensive effect of captopril in sinoaortic denervated rats
    • Höcht, C.; Gironacci, M.M.; Mayer, M.A.; Schuman, M.; Bertera, F.M.; Taira, C.A. Involvement of angiotensin-(1-7) in the hypothalamic hypotensive effect of captopril in sinoaortic denervated rats. Regul. Pept., 2008, 146(1-3), 58-66.
    • (2008) Regul. Pept , vol.146 , Issue.1-3 , pp. 58-66
    • Höcht, C.1    Gironacci, M.M.2    Mayer, M.A.3    Schuman, M.4    Bertera, F.M.5    Taira, C.A.6
  • 47
    • 0141458359 scopus 로고    scopus 로고
    • Hypotensive function of the brain angiotensin-(1-7) in Sprague Dawley and renin transgenic rats
    • Dobruch, J.; Paczwa, P.; Łoń, S.; Khosla, M.C.; Szczepańska-Sadowska, E. Hypotensive function of the brain angiotensin-(1-7) in Sprague Dawley and renin transgenic rats. J. Physiol. Pharmacol., 2003, 54, 371-381.
    • (2003) J. Physiol. Pharmacol , vol.54 , pp. 371-381
    • Dobruch, J.1    Paczwa, P.2    Łoń, S.3    Khosla, M.C.4    Szczepańska-Sadowska, E.5
  • 49
    • 77956394458 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 attenuates the angiotensin II-induced upregulation of angiotensin II type 1 receptor in CATH a neurons
    • Xiao, L.; Gao, L.; Zucker, I.H. Angiotensin-converting enzyme 2 attenuates the angiotensin II-induced upregulation of angiotensin II type 1 receptor in CATH a neurons. Hypertension, 2009, 54, e70.
    • (2009) Hypertension , vol.54
    • Xiao, L.1    Gao, L.2    Zucker, I.H.3
  • 50
    • 41449089986 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation
    • Feng, Y.; Yue, X.; Xia, H.; Bindom, S.M.; Hickman, P.J.; Filipeanu, C.M.; Wu, G.; Lazartigues, E. Angiotensin-converting enzyme 2 overexpression in the subfornical organ prevents the angiotensin II-mediated pressor and drinking responses and is associated with angiotensin II type 1 receptor downregulation. Circ. Res., 2008, 102, 729-736.
    • (2008) Circ. Res , vol.102 , pp. 729-736
    • Feng, Y.1    Yue, X.2    Xia, H.3    Bindom, S.M.4    Hickman, P.J.5    Filipeanu, C.M.6    Wu, G.7    Lazartigues, E.8
  • 51
    • 26244431682 scopus 로고    scopus 로고
    • Arterial baroreflex dysfunction promotes atherosclerosis in rats
    • Cai, G.J.; Miao, C.Y.; Xie, H.H.; Lu, L.H.; Su, D.F. Arterial baroreflex dysfunction promotes atherosclerosis in rats. Atherosclerosis, 2005, 183, 41-47.
    • (2005) Atherosclerosis , vol.183 , pp. 41-47
    • Cai, G.J.1    Miao, C.Y.2    Xie, H.H.3    Lu, L.H.4    Su, D.F.5
  • 52
    • 83155192160 scopus 로고    scopus 로고
    • Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity and enhances baroreflex function in chronic heart failure
    • Xiao, L.; Gao, L.; Lazartigues, E.; Zucker, I.H. Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity and enhances baroreflex function in chronic heart failure. Hypertension, 2011, 58, 1057-1065.
    • (2011) Hypertension , vol.58 , pp. 1057-1065
    • Xiao, L.1    Gao, L.2    Lazartigues, E.3    Zucker, I.H.4
  • 54
    • 0031792945 scopus 로고    scopus 로고
    • Interaction of bradykinin and angiotensin-(1-7) in the central modulation of the baroreflex control of the heart rate
    • Bomtempo, C.A.; Santos, G.F.; Santos, R.A.; Campagnole-Santos, M.J. Interaction of bradykinin and angiotensin-(1-7) in the central modulation of the baroreflex control of the heart rate. J. Hypertens., 1998, 16, 1797-1804.
    • (1998) J. Hypertens , vol.16 , pp. 1797-1804
    • Bomtempo, C.A.1    Santos, G.F.2    Santos, R.A.3    Campagnole-Santos, M.J.4
  • 55
    • 80053556070 scopus 로고    scopus 로고
    • Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure
    • Kar, S.; Gao, L.; Belatti, D.A.; Curry, P.L.; Zucker, I.H. Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure. Hypertension, 2011, 58, 627-634.
    • (2011) Hypertension , vol.58 , pp. 627-634
    • Kar, S.1    Gao, L.2    Belatti, D.A.3    Curry, P.L.4    Zucker, I.H.5
  • 56
    • 79954426342 scopus 로고    scopus 로고
    • Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system
    • Zimmerman, M.C. Angiotensin II and angiotensin-1-7 redox signaling in the central nervous system. Curr. Opin. Pharmacol., 2011, 11, 138-143.
    • (2011) Curr. Opin. Pharmacol , vol.11 , pp. 138-143
    • Zimmerman, M.C.1
  • 57
    • 0027462564 scopus 로고
    • Angiotensin-(1-7) and nitric oxide synthase in the hypothalamo-neurohypophysial system
    • Calka, J.; Block, C.H. Angiotensin-(1-7) and nitric oxide synthase in the hypothalamo-neurohypophysial system. Brain. Res. Bull., 1993, 30, 677-685.
    • (1993) Brain. Res. Bull , vol.30 , pp. 677-685
    • Calka, J.1    Block, C.H.2
  • 58
    • 33847018997 scopus 로고    scopus 로고
    • Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt dependent pathways
    • Sampaio, W.O.; Souza dos Santos, R.A.; Faria-Silva, R.; da Mata Machado, L.T.; Schiffrin, E.L.; Touyz, R.M. Angiotensin-(1-7) through receptor Mas mediates endothelial nitric oxide synthase activation via Akt dependent pathways. Hypertension, 2007, 49, 185-192.
    • (2007) Hypertension , vol.49 , pp. 185-192
    • Sampaio, W.O.1    dos Santos, R.A.S.2    Faria-Silva, R.3    da Mata, M.L.T.4    Schiffrin, E.L.5    Touyz, R.M.6
  • 59
    • 61849153939 scopus 로고    scopus 로고
    • Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension
    • Nagae, A.; Fujita, M.; Kawarazaki, H.; Matsui, H.; Ando, K.; Fujita, T. Sympathoexcitation by oxidative stress in the brain mediates arterial pressure elevation in obesity-induced hypertension. Circulation, 2009, 119, 978-986.
    • (2009) Circulation , vol.119 , pp. 978-986
    • Nagae, A.1    Fujita, M.2    Kawarazaki, H.3    Matsui, H.4    Ando, K.5    Fujita, T.6
  • 61
    • 79960810124 scopus 로고    scopus 로고
    • ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function
    • Xia, H.; Suda, S.; Bindom, S.; Feng, Y.; Gurley, S.B.; Seth, D.; Navar, L.G.; Lazartigues, E. ACE2-mediated reduction of oxidative stress in the central nervous system is associated with improvement of autonomic function. PLoS One, 2011, 6, e22682.
    • (2011) PLoS One , vol.6
    • Xia, H.1    Suda, S.2    Bindom, S.3    Feng, Y.4    Gurley, S.B.5    Seth, D.6    Navar, L.G.7    Lazartigues, E.8
  • 62
    • 84863873052 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway
    • Xing, J.; Kong, J.; Lu, J.; Li, J. Angiotensin-(1-7) inhibits neuronal activity of dorsolateral periaqueductal gray via a nitric oxide pathway. Neurosci. Lett., 2012, 522, 156-161.
    • (2012) Neurosci. Lett , vol.522 , pp. 156-161
    • Xing, J.1    Kong, J.2    Lu, J.3    Li, J.4
  • 63
    • 7244240604 scopus 로고    scopus 로고
    • Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats
    • Gironacci, M.M.; Valera, M.S.; Yujnovsky, I.; Pena, C. Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats. Hypertension, 2004, 44, 783-787.
    • (2004) Hypertension , vol.44 , pp. 783-787
    • Gironacci, M.M.1    Valera, M.S.2    Yujnovsky, I.3    Pena, C.4
  • 64
    • 62649166390 scopus 로고    scopus 로고
    • Angiotensin-(1-7) through AT receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway
    • Lopez Verrilli, M.A.; Pirola, C.J.; Pascual, M.M.; Dominici, F.P.; Turyn, D.; Gironacci, M.M. Angiotensin-(1-7) through AT receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway. J. Neurochem., 2009, 109, 326-335.
    • (2009) J. Neurochem , vol.109 , pp. 326-335
    • Lopez, V.M.A.1    Pirola, C.J.2    Pascual, M.M.3    Dominici, F.P.4    Turyn, D.5    Gironacci, M.M.6
  • 65
    • 78651375228 scopus 로고    scopus 로고
    • Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism
    • Yang, R.F., Yin, J.X.; Li, Y.L.; Zimmerman, M.C.; Schultz, H.D. Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism. Am. J. Physiol. Cell. Physiol., 2011, 300, C58-64.
    • (2011) Am. J. Physiol. Cell. Physiol , vol.300
    • Yang, R.F.1    Yin, J.X.2    Li, Y.L.3    Zimmerman, M.C.4    Schultz, H.D.5
  • 66
    • 79952115288 scopus 로고    scopus 로고
    • Intracranial atherosclerosis: Current concepts
    • Arenillas, J.F. Intracranial atherosclerosis: current concepts. Stroke, 2011, 42, S20-23.
    • (2011) Stroke , vol.42
    • Arenillas, J.F.1
  • 70
    • 77957881110 scopus 로고    scopus 로고
    • Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration
    • Zhang, F.; Hu, Y.; Xu, Q.; Ye, S. Different effects of angiotensin II and angiotensin-(1-7) on vascular smooth muscle cell proliferation and migration. PLoS One 2010, 5, e12323.
    • (2010) PLoS One , vol.5
    • Zhang, F.1    Hu, Y.2    Xu, Q.3    Ye, S.4
  • 72
    • 84868298825 scopus 로고    scopus 로고
    • AVE0991, a Nonpeptide Compound, Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation via Induction of Heme Oxygenase-1 and Downregulation of p-38 MAPK Phosphorylation
    • Sheng-Long, C.; Yan-Xin, W.; Yi-Yi, H.; Ming, F.; Jian-Gui, H.; Yi-Li, C.; Wen-Jing, X.; Hong, M. AVE0991, a Nonpeptide Compound, Attenuates Angiotensin II-Induced Vascular Smooth Muscle Cell Proliferation via Induction of Heme Oxygenase-1 and Downregulation of p-38 MAPK Phosphorylation. Int. J. Hypertens., 2012, 2012, 958298.
    • (2012) Int. J. Hypertens , vol.2012 , pp. 958298
    • Sheng-Long, C.1    Yan-Xin, W.2    Yi-Yi, H.3    Ming, F.4    Jian-Gui, H.5    Yi-Li, C.6    Wen-Jing, X.7    Hong, M.8
  • 73
    • 40349087454 scopus 로고    scopus 로고
    • The antithrombotic effect of angiotensin- (1-7) involves mas-mediated NO release from platelets
    • Fraga-Silva, R.A.; Pinheiro, S.V.; Gonçalves, A.C.; Alenina, N.; Bader, M.; Santos, R.A. The antithrombotic effect of angiotensin- (1-7) involves mas-mediated NO release from platelets. Mol. Med., 2008, 14, 28-35.
    • (2008) Mol. Med , vol.14 , pp. 28-35
    • Fraga-Silva, R.A.1    Pinheiro, S.V.2    Gonçalves, A.C.3    Alenina, N.4    Bader, M.5    Santos, R.A.6
  • 74
    • 0036841147 scopus 로고    scopus 로고
    • Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7)
    • Kucharewicz, I.; Pawlak, R.; Matys, T.; Pawlak, D.; Buczko, W. Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7). Hypertension, 2002, 40, 774-779.
    • (2002) Hypertension , vol.40 , pp. 774-779
    • Kucharewicz, I.1    Pawlak, R.2    Matys, T.3    Pawlak, D.4    Buczko, W.5
  • 75
    • 77449152992 scopus 로고    scopus 로고
    • Oxidative stress and its role in the pathogenesis of ischaemic stroke
    • Allen, C.L.; Bayraktutan, U. Oxidative stress and its role in the pathogenesis of ischaemic stroke. Int. J. Stroke, 2009, 4, 461-470.
    • (2009) Int. J. Stroke , vol.4 , pp. 461-470
    • Allen, C.L.1    Bayraktutan, U.2
  • 76
    • 0025697262 scopus 로고
    • Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury
    • Janero, D.R. Malondialdehyde and thiobarbituric acid-reactivity as diagnostic indices of lipid peroxidation and peroxidative tissue injury. Free Radic. Biol. Med., 1990, 9, 515-540.
    • (1990) Free Radic. Biol. Med , vol.9 , pp. 515-540
    • Janero, D.R.1
  • 78
    • 84867313160 scopus 로고    scopus 로고
    • Interrelation between inflammation, thrombosis, and neuroprotection in cerebral ischemia
    • van der Spuy, W.J.; Pretorius, E. Interrelation between inflammation, thrombosis, and neuroprotection in cerebral ischemia. Rev. Neurosci., 2012, 23, 269-278.
    • (2012) Rev. Neurosci , vol.23 , pp. 269-278
    • van der Spuy, W.J.1    Pretorius, E.2
  • 79
    • 59349107204 scopus 로고    scopus 로고
    • NF-kappaB signaling in cerebral ischemia
    • Ridder, D.A.; Schwaninger, M. NF-kappaB signaling in cerebral ischemia. Neuroscience, 2009, 158, 995-1006.
    • (2009) Neuroscience , vol.158 , pp. 995-1006
    • Ridder, D.A.1    Schwaninger, M.2
  • 80
    • 84856229622 scopus 로고    scopus 로고
    • Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia
    • Zhu, J.; Jiang, Y.; Wu, L.; Lu, T.; Xu, G.; Liu, X. Suppression of local inflammation contributes to the neuroprotective effect of ginsenoside Rb1 in rats with cerebral ischemia. Neuroscience, 2012, 202, 342-351
    • (2012) Neuroscience , vol.202 , pp. 342-351
    • Zhu, J.1    Jiang, Y.2    Wu, L.3    Lu, T.4    Xu, G.5    Liu, X.6
  • 81
    • 77956326833 scopus 로고    scopus 로고
    • Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia
    • Chan, S.J.; Wong, W.S.; Wong, P.T.; Bian, J.S. Neuroprotective effects of andrographolide in a rat model of permanent cerebral ischaemia. Br. J. Pharmacol., 2010, 161, 668-679
    • (2010) Br. J. Pharmacol , vol.161 , pp. 668-679
    • Chan, S.J.1    Wong, W.S.2    Wong, P.T.3    Bian, J.S.4
  • 82
    • 80052025635 scopus 로고    scopus 로고
    • Protective effect of Etoricoxib against middle cerebral artery occlusion induced transient focal cerebral ischemia in rats
    • Shwari, A.; Badgujar, L.; Phukan, B.; Bodhankar, S.L.; Thakurdesai, P. Protective effect of Etoricoxib against middle cerebral artery occlusion induced transient focal cerebral ischemia in rats. Eur. J. Pharmacol., 2011, 667, 230-237.
    • (2011) Eur. J. Pharmacol , vol.667 , pp. 230-237
    • Shwari, A.1    Badgujar, L.2    Phukan, B.3    Bodhankar, S.L.4    Thakurdesai, P.5
  • 83
    • 0036842344 scopus 로고    scopus 로고
    • Transient focal ischemia increases endothelial nitric oxide synthase in cerebral blood vessels
    • Veltkamp, R.; Rajapakse, N.; Robins, G.; Puskar, M.; Shimizu, K.; Busija, D. Transient focal ischemia increases endothelial nitric oxide synthase in cerebral blood vessels. Stroke, 2002, 33, 2704-2710.
    • (2002) Stroke , vol.33 , pp. 2704-2710
    • Veltkamp, R.1    Rajapakse, N.2    Robins, G.3    Puskar, M.4    Shimizu, K.5    Busija, D.6
  • 84
    • 7644234326 scopus 로고    scopus 로고
    • Modification of endothelial NO synthase through protein phosphorylation after forebrain cerebral ischemia/ reperfusion
    • Osuka, K.; Watanabe, Y.; Usuda, N.; Nakazawa, A.; Tokuda, M.; Yoshida, J. Modification of endothelial NO synthase through protein phosphorylation after forebrain cerebral ischemia/ reperfusion. Stroke, 2004, 35, 2582-2586.
    • (2004) Stroke , vol.35 , pp. 2582-2586
    • Osuka, K.1    Watanabe, Y.2    Usuda, N.3    Nakazawa, A.4    Tokuda, M.5    Yoshida, J.6
  • 85
    • 0030664096 scopus 로고    scopus 로고
    • Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene
    • Iadecola, C.; Zhang, F.; Casey, R.; Nagayama, M.; Ross, M.E. Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene. J. Neurosci., 1997, 17, 9157-9164.
    • (1997) J. Neurosci , vol.17 , pp. 9157-9164
    • Iadecola, C.1    Zhang, F.2    Casey, R.3    Nagayama, M.4    Ross, M.E.5
  • 87
    • 56349133166 scopus 로고    scopus 로고
    • Central administration of angiotensin-(1-7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats
    • Zhang, Y.; Lu, J.; Shi, J.; Lin, X.; Dong, J.; Zhang, S.; Liu, Y,; Tong, Q. Central administration of angiotensin-(1-7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats. Neuropeptides, 2008, 42, 593-600.
    • (2008) Neuropeptides , vol.42 , pp. 593-600
    • Zhang, Y.1    Lu, J.2    Shi, J.3    Lin, X.4    Dong, J.5    Zhang, S.6    Liu, Y.7    Tong, Q.8
  • 88
    • 32844461449 scopus 로고    scopus 로고
    • Experimental therapywith tissue kallikrein against cerebral ischemia
    • Chao, J.; Chao, L. Experimental therapywith tissue kallikrein against cerebral ischemia. Front. Biosci., 2006, 11, 1323-1327.
    • (2006) Front. Biosci , vol.11 , pp. 1323-1327
    • Chao, J.1    Chao, L.2
  • 90
    • 0035569026 scopus 로고    scopus 로고
    • Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade
    • Tom, B.; de Vries, R.; Saxena, P.R.; Danser, A.H.J. Bradykinin potentiation by angiotensin-(1-7) and ACE inhibitors correlates with ACE C- and N-domain blockade. Hypertension, 2001, 38, 95-99.
    • (2001) Hypertension , vol.38 , pp. 95-99
    • Tom, B.1    de Vries, R.2    Saxena, P.R.3    Danser, A.H.J.4
  • 91
    • 45849126088 scopus 로고    scopus 로고
    • Effects of intracerebroventricular infusion of angiotensin-(1-7) on bradykinin formation and the kinin receptor expression after focal cerebral ischemia-reperfusion in rats
    • Lu, J.; Zhang, Y.; Shi, J. Effects of intracerebroventricular infusion of angiotensin-(1-7) on bradykinin formation and the kinin receptor expression after focal cerebral ischemia-reperfusion in rats. Brain Res., 2008, 1219, 127-135.
    • (2008) Brain Res , vol.1219 , pp. 127-135
    • Lu, J.1    Zhang, Y.2    Shi, J.3
  • 93
    • 56749182432 scopus 로고    scopus 로고
    • Angiotensin-converting enzyme 2 in the brain: Properties and future directions
    • Xia, H.; Lazartigues, E. Angiotensin-converting enzyme 2 in the brain: properties and future directions. J. Neurochem., 2008, 107, 1482-1494.
    • (2008) J. Neurochem , vol.107 , pp. 1482-1494
    • Xia, H.1    Lazartigues, E.2
  • 96
    • 33847780798 scopus 로고    scopus 로고
    • Pharmacological effects of AVE 0991, a nonpeptide angiotensin-(1-7) receptor agonist
    • Santos, R.A.; Ferreira, A.J. Pharmacological effects of AVE 0991, a nonpeptide angiotensin-(1-7) receptor agonist. Cardiovasc. Drug Rev., 2006, 24, 239-246.
    • (2006) Cardiovasc. Drug Rev , vol.24 , pp. 239-246
    • Santos, R.A.1    Ferreira, A.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.