Central angiotensin (1-7) enhances baroreflex gain in conscious rabbits with heart failure

Hypertension

Volumn 58, Issue 4, 2011, Pages 627-634

  Kar, Sumit ^a   Gao, Lie ^a   Belatti, Daniel A ^a   Curry, Pamela L ^a   Zucker, Irving H ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

Author keywords

angiotensin (1 7); baroreflex; blood pressure; heart failure; heart rate; sympathetic nervous system; vagus nerve

Indexed keywords

ANGIOTENSIN[1-7]; METOPROLOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBROSPINAL FLUID; CONTROLLED STUDY; HEART FAILURE; HEART RATE; MALE; NERVE CONDUCTION; NONHUMAN; OSMOTIC MINIPUMP; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; RABBIT; RENAL SYMPATHETIC NERVE ACTIVITY; VAGUS NERVE;

ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BAROREFLEX; CHRONIC DISEASE; CONSCIOUSNESS; DISEASE MODELS, ANIMAL; HEART FAILURE; HEART RATE; INFUSIONS, INTRAVENTRICULAR; KIDNEY; MALE; METOPROLOL; PEPTIDE FRAGMENTS; RABBITS; SYMPATHETIC NERVOUS SYSTEM; VAGUS NERVE;

EID: 80053556070     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.177600     Document Type: Article

References (41)

1. Floras JS. Clinical aspects of sympathetic activation and parasympathetic withdrawal in heart failure. J Am Coll Cardiol. 1993;22:72A-84A. (Pubitemid 23285800)
2. Francis GS. Neurohumoral mechanisms involved in congestive heart failure. Am J Cardiol. 1985;55:15A-21A. (Pubitemid 15189933)
3. Francis GS. The relationship of the sympathetic nervous system and the renin-angiotensin system in congestive heart failure. Am Heart J. 1989; 118:642-648. (Pubitemid 19222071)
4. Wang W, Gao L, Wang H, Zucker IH, Wang W. Interaction between cardiac sympathetic afferent reflex and chemoreflex is mediated by the NTS AT1 receptors in heart failure. Am J Physiol Heart Circ Physiol. 2008;295:H1216-H1226.
5. DiBona GF, Jones SY, Brooks VL. ANG II receptor blockade and arterial baroreflex regulation of renal nerve activity in cardiac failure. Am J Physiol Regul Integr Comp Physiol. 1995;269:R1189-R1196. (Pubitemid 3006002)
6. Heringer-Walther S, Batista EN, Walther T, Khosla MC, Santos RAS, Campagnole-Santos MJ. Baroreflex improvement in SHR after ACE inhibition involves angiotensin-(1-7). Hypertension. 2001;37:1309-1314. (Pubitemid 34163587)
7. Kar S, Gao L, Zucker IH. Exercise training normalizes ACE and ACE2 in the brain of rabbits with pacing-induced heart failure. J Appl Physiol. 2010;108:923-932.
8. Brosnihan KB, Li P, Ferrario CM. Angiotensin-(1-7) dilates canine coronary arteries through kinins and nitric oxide. Hypertension. 1996;27: 523-528. (Pubitemid 26086221)
9. Averill DB, Ishiyama Y, Chappell MC, Ferrario CM. Cardiac angiotensin-( 1-7) in ischemic cardiomyopathy. Circulation. 2003;108:2141-2146. (Pubitemid 37337592)
10. Wang Y, Qian C, Roks AJM, Westermann D, Schumacher S, Escher F, Schoemaker RG, Reudelhuber TL, Van Gilst WH, Schultheiss H, Tschöpe C, Walther T. Circulating rather than cardiac angiotensin-(1-7) stimulates cardioprotection after myocardial infarction. Circ Heart Fail. 2010;3: 286-293.
11. Giani JF, Muñoz MC, Mayer MA, Veiras LC, Arranz C, Taira CA, Turyn D, Toblli JE, Dominici FP. Angiotensin-(1-7) improves cardiac remodeling and inhibits growth-promoting pathways in the heart of fructose-fed rats. Am J Physiol Heart Circ Physiol. 2010;298: H1003-H1013.
12. Benter IF, Yousif MH, Anim JT, Cojocel C, Diz DI. Angiotensin-(1-7) prevents development of severe hypertension and end-organ damage in spontaneously hypertensive rats treated with L-NAME. Am J Physiol Heart Circ Physiol. 2006;290:H684-H691.
13. Chappell MC, Brosnihan KB, Diz DI, Ferrario CM. Identification of angiotensin-(1-7) in rat brain. evidence for differential processing of angiotensin peptides. J Biol Chem. 1989;264:16518-16523. (Pubitemid 19243542)
14. Schiavone MT, Santos RA, Brosnihan KB, Khosla MC, Ferrario CM. Release of vasopressin from the rat hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide. Proc Natl Acad Sci USA. 1988;85:4095-4098.
15. Potts PD, Horiuchi J, Coleman MJ, Dampney RAL. The cardiovascular effects of angiotensin-(1-7) in the rostral and caudal ventrolateral medulla of the rabbit. Brain Res. 2000;877:58-64.
16. Gomes da Silva AQ, Sousa dos Santos RA, Peliky Fontes MA. Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone. Hypertension. 2005;46:341-348. (Pubitemid 41099167)
17. Silva LCS, Fontes MAP, Campagnole-Santos MJ, Khosla MC, Campos RR Jr, Guertzenstein PG, Santos RAS. Cardiovascular effects produced by micro-injection of angiotensin-(1-7) on vasopressor and vasodepressor sites of the ventrolateral medulla. Brain Res. 1993;613:321-325. (Pubitemid 23179990)
18. Ferrario CM, Chappell MC, Tallant EA, Brosnihan KB, Diz DI. Counterregulatory actions of angiotensin-(1-7). Hypertension. 1997;30: 535-541. (Pubitemid 27444228)
19. Campagnole-Santos MJ, Guimarães P. Angiotensin-(1-7) ICV chronic infusion attenuates DOCA-salt hypertension. FASEB J. 2008;22:953.12.
20. Liu JL, Kulakofsky J, Zucker IH. Exercise training enhances baroreflex control of heart rate by a vagal mechanism in rabbits with heart failure. J Appl Physiol. 2002;92:2403-2408. (Pubitemid 34666365)
21. Campagnole-Santos MJ, Heringer SB, Batista EN, Khosla MC, Santos RA. Differential baroreceptor reflex modulation by centrally infused angiotensin peptides. Am J Physiol Regul Integr Comp Physiol. 1992; 263:R89-R94.
22. Diz DI, Garcia-Espinosa MA, Gallagher PE, Ganten D, Ferrario CM, Averill DB. Angiotensin-(1-7) and baroreflex function in nucleus tractus solitarii of (mRen2)27 transgenic rats. J Cardiovasc Pharmacol. 2008; 51:542-548.
23. Mousa TM, Gao L, Cornish KG, Zucker IH. Effects of angiotensin II on autonomic components of nasopharyngeal stimulation in male conscious rabbits. J Appl Physiol. 2005;98:1607-1611. (Pubitemid 40570766)
24. Liu JL, Irvine S, Reid IA, Patel KP, Zucker IH. Chronic exercise reduces sympathetic nerve activity in rabbits with pacing-induced heart failure: a role for angiotensin II. Circulation. 2000;102:1854-1862.
25. Liu J, Zucker IH. Regulation of sympathetic nerve activity in heart failure: a role for nitric oxide and angiotensin II. Circ Res. 1999;84: 417-423. (Pubitemid 29120007)
26. Gironacci MM, Valera MS, Yujnovsky I, Pena C. Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats. Hypertension. 2004;44:783-787. (Pubitemid 39435254)
27. Averill DB, Diz DI. Angiotensin peptides and baroreflex control of sympathetic outflow: pathways and mechanisms of the medulla oblongata. Brain Res Bull. 2000;51:119-128. (Pubitemid 30069873)
28. Matsumura K, Averill DB, Ferrario CM. Angiotensin II acts at AT1receptors in the nucleus of the solitary tract to attenuate the baroreceptor reflex. Am J Physiol Regul Integr Comp Physiol. 1998;275: R1611-R1619.
29. Sakima A, Averill DB, Kasper SO, Jackson L, Ganten D, Ferrario CM, Gallagher PE, Diz DI. Baroreceptor reflex regulation in anesthetized transgenic rats with low glia-derived angiotensinogen. Am J Physiol Heart Circ Physiol. 2007;292:H1412-H1419. (Pubitemid 46380245)
30. Campagnole-Santos MJ, Diz DI, Santos RA, Khosla MC, Brosnihan KB, Ferrario CM. Cardiovascular effects of angiotensin-(1-7) injected into the dorsal medulla of rats. Am J Physiol Heart Circ Physiol. 1989;257: H324-H329.
31. Barnes KL, Knowles WD, Ferrario CM. Angiotensin II and angiotensin (1-7) excite neurons in the canine medulla in vitro. Brain Res Bull. 1990;24:275-280. (Pubitemid 20107453)
32. Becker LK, Etelvino GM, Walther T, Santos RAS, Campagnole-Santos MJ. Immunofluorescence localization of the receptor mas in cardiovascular-related areas of the rat brain. Am J Physiol Heart Circ Physiol. 2007;293:H1416-H1424. (Pubitemid 47367184)
33. Yang R, Yin J, Li Y, Zimmerman MC, Schultz HD. Angiotensin-(1-7) increases neuronal potassium current via a nitric oxide-dependent mechanism. Am J Physiol Cell Physiol. 2011;300:C58-C64.
34. Gao L, Li Y, Schultz HD, Wang W, Wang W, Finch M, Smith LM, Zucker IH. Downregulated Kv4.3 expression in the RVLM as a potential mechanism for sympathoexcitation in rats with chronic heart failure. Am J Physiol Heart Circ Physiol. 2010;298:H945-H955.
35. Walters PE, Gaspari TA, Widdop RE. Angiotensin-(1-7) acts as a vasodepressor agent via angiotensin II type 2 receptors in conscious rats. Hypertension. 2005;45:960-966. (Pubitemid 40628944)
36. Rowe BP, Saylor DL, Speth RC, Absher DR. Angiotensin-(1-7) binding at angiotensin II receptors in the rat brain. Regul Pept. 1995;56:139-146.
37. de Castro CH, Souza dos Santos RA, Ferreira AJ, Bader M, Alenina N, Pinto de Almeida A. Evidence for a functional interaction of the angiotensin-( 1-7) receptor mas with AT1 and AT2 receptors in the mouse heart. Hypertension. 2005;46:937-942.
38. Grobe JL, Xu D, Sigmund CD. An intracellular renin-angiotensin system in neurons: fact, hypothesis, or fantasy. Physiology. 2008;23: 187-193.
39. Shenoy V, Qi Y, Katovich MJ, Raizada MK. ACE2, a promising therapeutic target for pulmonary hypertension. Curr Opin Pharmacol. 2011; 11:150-155.
40. Zhong J, Guo D, Chen CB, Wang W, Schuster M, Loibner H, Penninger JM, Scholey JW, Kassiri Z, Oudit GY. Prevention of angiotensin II-mediated renal oxidative stress, inflammation, and fibrosis by angiotensin-converting enzyme 2. Hypertension. 2011;57:314-322.
41. Zhong J, Basu R, Guo D, Chow FL, Byrns S, Schuster M, Loibner H, Wang X, Penninger JM, Kassiri Z, Oudit GY. Angiotensin-converting enzyme 2 suppresses pathological hypertrophy, myocardial fibrosis, and cardiac dysfunction. Circulation. 2010;122:717-728.