메뉴 건너뛰기




Volumn 163, Issue 6, 2011, Pages 1122-1130

Role of angiotensin II receptor subtype activation in cognitive function and ischaemic brain damage

Author keywords

angiotensin II; cognitive impairment; hypertension; receptor; stroke

Indexed keywords

1 (4 AMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDROIMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; 1 (4 DIMETHYLAMINO 3 METHYLBENZYL) 5 DIPHENYLACETYL 4,5,6,7 TETRAHYDRO 1H IMIDAZO[4,5 C]PYRIDINE 6 CARBOXYLIC ACID; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 1 RECEPTOR ANTAGONIST; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN RECEPTOR; ANGIOTENSIN RECEPTOR ANTAGONIST; COMPOUND 21; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HORMONE RECEPTOR STIMULATING AGENT; HYDRALAZINE; NICOTINOYLTYROSYL(N BENZYLOXYCARBONYLARGINYL)LYSYLHISTIDYLPROLYLISOLEUCINE; OLMESARTAN; TELMISARTAN; UNCLASSIFIED DRUG; VALSARTAN;

EID: 79959736871     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2010.01167.x     Document Type: Review
Times cited : (60)

References (83)
  • 1
    • 72149097863 scopus 로고    scopus 로고
    • Guide to Receptors and Channels (GRAC), 4th edition
    • (Suppl.).
    • Alexander SP, Mathie A, Peters JA, (2009). Guide to Receptors and Channels (GRAC), 4th edition. Br J Pharmacol 158 (Suppl. 1): S1-S254.
    • (2009) Br J Pharmacol , vol.158 , Issue.1
    • Alexander, S.P.1    Mathie, A.2    Peters, J.A.3
  • 3
    • 76449117787 scopus 로고    scopus 로고
    • Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats
    • Bosnyak S, Welungoda IK, Hallberg A, Alterman M, Widdop RE, Jones ES, (2010). Stimulation of angiotensin AT2 receptors by the non-peptide agonist, Compound 21, evokes vasodepressor effects in conscious spontaneously hypertensive rats. Br J Pharmacol 159: 709-716.
    • (2010) Br J Pharmacol , vol.159 , pp. 709-716
    • Bosnyak, S.1    Welungoda, I.K.2    Hallberg, A.3    Alterman, M.4    Widdop, R.E.5    Jones, E.S.6
  • 4
    • 10044225937 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ induces a clearance mechanism for the amyloid-β peptide
    • DOI 10.1523/JNEUROSCI.3987-04.2004
    • Camacho IE, Serneels L, Spittaels K, Merchiers P, Dominguez D, De Strooper B, (2004). Peroxisome-proliferator-activated receptor gamma induces a clearance mechanism for the amyloid-beta peptide. J Neurosci 24: 10908-10917. (Pubitemid 39602402)
    • (2004) Journal of Neuroscience , vol.24 , Issue.48 , pp. 10908-10917
    • Camacho, I.E.1    Serneels, L.2    Spittaels, K.3    Merchiers, P.4    Dominguez, D.5    De Strooper, B.6
  • 5
    • 0035149749 scopus 로고    scopus 로고
    • Reactive oxygen radicals in signaling and damage in the ischemic brain
    • Chan PH, (2001). Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 21: 2-14. (Pubitemid 32036708)
    • (2001) Journal of Cerebral Blood Flow and Metabolism , vol.21 , Issue.1 , pp. 2-14
    • Chan, P.H.1
  • 6
    • 0038190097 scopus 로고    scopus 로고
    • Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum
    • Cote F, Do TH, Laflamme L, Gallo JM, Gallo-Payet N, (1999). Activation of the AT(2) receptor of angiotensin II induces neurite outgrowth and cell migration in microexplant cultures of the cerebellum. J Biol Chem 274: 31686-31692.
    • (1999) J Biol Chem , vol.274 , pp. 31686-31692
    • Cote, F.1    Do, T.H.2    Laflamme, L.3    Gallo, J.M.4    Gallo-Payet, N.5
  • 7
    • 0032428097 scopus 로고    scopus 로고
    • Nitric oxide, a new second messenger involved in the action of angiotensin II on neuronal differentiation of NG108-15 cells
    • Cote F, Laflamme L, Payet MD, Gallo-Payet N, (1998). Nitric oxide, a new second messenger involved in the action of angiotensin II on neuronal differentiation of NG108-15 cells. Endocr Res 24: 403-407. (Pubitemid 29016414)
    • (1998) Endocrine Research , vol.24 , Issue.3-4 , pp. 403-407
    • Cote, F.1    Laflamme, L.2    Payet, M.D.3    Gallo-Payet, N.4
  • 9
    • 0032538972 scopus 로고    scopus 로고
    • The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes
    • Davisson RL, Yang G, Beltz TG, Cassell MD, Jhonson AK, Sigmund CD, (1998). The brain renin-angiotensin system contributes to the hypertension in mice containing both the human renin and human angiotensinogen transgenes. Circ Res 83: 1047-1058. (Pubitemid 28520934)
    • (1998) Circulation Research , vol.83 , Issue.10 , pp. 1047-1058
    • Davisson, R.L.1    Yang, G.2    Beltz, T.G.3    Cassell, M.D.4    Johnson, A.K.5    Sigmund, C.D.6
  • 12
    • 0034056523 scopus 로고    scopus 로고
    • Impaired endothelial function in transgenic mice expressing both human renin and human angiotensinogen
    • Didion SP, Sigmund CD, Faraci FM, (2000). Impaired endothelial function in transgenic mice expressing both human renin and human angiotensinogen. Stroke 31: 760-765. (Pubitemid 30131667)
    • (2000) Stroke , vol.31 , Issue.3 , pp. 760-765
    • Didion, S.P.1    Sigmund, C.D.2    Faraci, F.M.3
  • 13
    • 1842473651 scopus 로고    scopus 로고
    • The Angiotensin II Type 1-Receptor Blocker Candesartan Increases Cerebral Blood Flow, Reduces Infarct Size, and Improves Neurologic Outcome after Transient Cerebral Ischemia in Rats
    • Engelhorn T, Goerike S, Doerfler A, Okorn C, Forsting M, Heusch G, et al,. (2004). The angiotensin II type 1-receptor blocker candesartan increases cerebral blood flow, reduces infarct size, and improves neurologic outcome after transient cerebral ischemia in rats. J Cereb Blood Flow Metab 24: 467-474. (Pubitemid 38455442)
    • (2004) Journal of Cerebral Blood Flow and Metabolism , vol.24 , Issue.4 , pp. 467-474
    • Engelhorn, T.1    Goerike, S.2    Doerfler, A.3    Okorn, C.4    Forsting, M.5    Heusch, G.6    Schulz, R.7
  • 17
    • 0033824138 scopus 로고    scopus 로고
    • International union of pharmacology. XXIII. The angiotensin II receptors
    • de Gasparo M, Catt KJ, Inagami T, Wright JW, Unger T, (2000). International union of pharmacology. XXIII. The angiotensin II receptors. Pharmacol Rev 52: 415-472.
    • (2000) Pharmacol Rev , vol.52 , pp. 415-472
    • De Gasparo, M.1    Catt, K.J.2    Inagami, T.3    Wright, J.W.4    Unger, T.5
  • 18
    • 73649119592 scopus 로고    scopus 로고
    • Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: Focus on renal damage
    • Gelosa P, Pignieri A, Fandriks L, de Gasparo M, Hallberg A, Banfi C, et al,. (2009). Stimulation of AT2 receptor exerts beneficial effects in stroke-prone rats: focus on renal damage. J Hypertens 27: 2444-2451.
    • (2009) J Hypertens , vol.27 , pp. 2444-2451
    • Gelosa, P.1    Pignieri, A.2    Fandriks, L.3    De Gasparo, M.4    Hallberg, A.5    Banfi, C.6
  • 19
    • 0033237655 scopus 로고    scopus 로고
    • 2 (angiotensin type 2) receptor of angiotensin II inhibit p21(ras) and activate MAPK (mitogen-activated protein kinase) to induce morphological neuronal differentiation in NG108-15 cells
    • Gendron L, Laflamme L, Rivard N, Asselin C, Payet MD, Gallo-Payet N, (1999). Signals from the AT2 (angiotensin type 2) receptor of angiotensin II inhibit p21ras and activate MAPK (mitogen-activated protein kinase) to induce morphological neuronal differentiation in NG108-15 cells. Mol Endocrinol 13: 1615-1626. (Pubitemid 30650600)
    • (1999) Molecular Endocrinology , vol.13 , Issue.9 , pp. 1615-1626
    • Gendron, L.1    Laflamme, L.2    Rivard, N.3    Asselin, C.4    Payet, M.D.5    Gallo-Payet, N.6
  • 20
    • 33748597376 scopus 로고    scopus 로고
    • Comparison of inhibitory action of candesartan and enalapril on brain ischemia through inhibition of oxidative stress
    • DOI 10.1016/j.neuropharm.2006.05.029, PII S0028390806001560
    • Hamai M, Iwai M, Ide A, Tomochika H, Tomono Y, Mogi M, et al,. (2006). Comparison of inhibitory action of candesartan and enalapril on brain ischemia through inhibition of oxidative stress. Neuropharmacology 51: 822-828. (Pubitemid 44376401)
    • (2006) Neuropharmacology , vol.51 , Issue.4 , pp. 822-828
    • Hamai, M.1    Iwai, M.2    Ide, A.3    Tomochika, H.4    Tomono, Y.5    Mogi, M.6    Horiuchi, M.7
  • 22
    • 0037568323 scopus 로고    scopus 로고
    • Identification of numerous genes differentially expressed in rat brain during postnatal development by suppression subtractive hybridization and expression analysis of the novel rat gene rMMS2
    • DOI 10.1016/S0169-328X(03)00060-3
    • Hofsaess U, Kapfhammer JP, (2003). Identification of numerous genes differentially expressed in rat brain during postnatal development by suppression subtractive hybridization and expression analysis of the novel rat gene rMMS2. Brain Res Mol Brain Res 113: 13-27. (Pubitemid 36579062)
    • (2003) Molecular Brain Research , vol.113 , Issue.1-2 , pp. 13-27
    • Hofsaess, U.1    Kapfhammer, J.P.2
  • 23
    • 0033031543 scopus 로고    scopus 로고
    • Recent progress in angiotensin II type 2 receptor research in the cardiovascular system
    • Horiuchi M, Akishita M, Dzau VJ, (1999). Recent progress in angiotensin II type 2 receptor research in the cardiovascular system. Hypertension 33: 613-621. (Pubitemid 29091636)
    • (1999) Hypertension , vol.33 , Issue.2 , pp. 613-621
    • Horiuchi, M.1    Akishita, M.2    Dzau, V.J.3
  • 24
    • 59849091253 scopus 로고    scopus 로고
    • Continuous activation of renin-angiotensin system impairs cognitive function in renin/angiotensinogen transgenic mice
    • Inaba S, Iwai M, Furuno M, Tomono Y, Kanno H, Senba I, et al,. (2009a). Continuous activation of renin-angiotensin system impairs cognitive function in renin/angiotensinogen transgenic mice. Hypertension 53: 356-362.
    • (2009) Hypertension , vol.53 , pp. 356-362
    • Inaba, S.1    Iwai, M.2    Furuno, M.3    Tomono, Y.4    Kanno, H.5    Senba, I.6
  • 25
    • 60549113487 scopus 로고    scopus 로고
    • Exaggeration of focal cerebral ischemia in transgenic mice carrying human renin and human angiotensinogen genes
    • Inaba S, Iwai M, Tomono Y, Senba I, Furuno M, Kanno H, et al,. (2009b). Exaggeration of focal cerebral ischemia in transgenic mice carrying human renin and human angiotensinogen genes. Stroke 40: 597-603.
    • (2009) Stroke , vol.40 , pp. 597-603
    • Inaba, S.1    Iwai, M.2    Tomono, Y.3    Senba, I.4    Furuno, M.5    Kanno, H.6
  • 27
    • 4143095706 scopus 로고    scopus 로고
    • Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation
    • DOI 10.1161/01.CIR.0000138848.58269.80
    • Iwai M, Liu HW, Chen R, Ide A, Okamoto S, Hata R, et al,. (2004). Possible inhibition of focal cerebral ischemia by angiotensin II type 2 receptor stimulation. Circulation 110: 843-848. (Pubitemid 39096013)
    • (2004) Circulation , vol.110 , Issue.7 , pp. 843-848
    • Iwai, M.1    Liu, H.-W.2    Chen, R.3    Ide, A.4    Okamoto, S.5    Hata, R.6    Sakanaka, M.7    Shiuchi, T.8    Horiuchi, M.9
  • 28
    • 52449102464 scopus 로고    scopus 로고
    • Deletion of angiotensin II type 2 receptor attenuates protective effects of bone marrow stromal cell treatment on ischemia-reperfusion brain injury in mice
    • Iwanami J, Mogi M, Li JM, Tsukuda K, Min LJ, Sakata A, et al,. (2008). Deletion of angiotensin II type 2 receptor attenuates protective effects of bone marrow stromal cell treatment on ischemia-reperfusion brain injury in mice. Stroke 39: 2554-2559.
    • (2008) Stroke , vol.39 , pp. 2554-2559
    • Iwanami, J.1    Mogi, M.2    Li, J.M.3    Tsukuda, K.4    Min, L.J.5    Sakata, A.6
  • 29
    • 77954954191 scopus 로고    scopus 로고
    • Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice
    • Iwanami J, Mogi M, Tsukuda K, Min LJ, Sakata A, Jing F, et al,. (2010). Low dose of telmisartan prevents ischemic brain damage with peroxisome proliferator-activated receptor-gamma activation in diabetic mice. J Hypertens 28: 1730-1737.
    • (2010) J Hypertens , vol.28 , pp. 1730-1737
    • Iwanami, J.1    Mogi, M.2    Tsukuda, K.3    Min, L.J.4    Sakata, A.5    Jing, F.6
  • 30
    • 0343907345 scopus 로고    scopus 로고
    • Localization of angiotensin-converting enzyme, angiotensin II, angiotensin II receptor subtypes, and vasopressin in the mouse hypothalamus
    • DOI 10.1016/S0006-8993(97)00220-5, PII S0006899397002205
    • Jöhren O, Imboden H, Häuser W, Maye I, Sanvitto GL, Saavedra JM, (1997). Localization of angiotensin-covertingenzyme, angiotensin II, angiotensin II receptor subtypes, and vasopressin in the mouse hypothalamus. Brain Res 757: 218-227. (Pubitemid 27244600)
    • (1997) Brain Research , vol.757 , Issue.2 , pp. 218-227
    • Johren, O.1    Imboden, H.2    Hauser, W.3    Maye, I.4    Sanvitto, G.L.5    Saavedra, J.M.6
  • 31
    • 58149375072 scopus 로고    scopus 로고
    • Angiotensin II type 2 receptor stimulation: A novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction?
    • Kaschina E, Grzesiak A, Li J, Foryst-Ludwig A, Timm M, Rompe F, et al,. (2008). Angiotensin II type 2 receptor stimulation: a novel option of therapeutic interference with the renin-angiotensin system in myocardial infarction? Circulation 118: 2523-2532.
    • (2008) Circulation , vol.118 , pp. 2523-2532
    • Kaschina, E.1    Grzesiak, A.2    Li, J.3    Foryst-Ludwig, A.4    Timm, M.5    Rompe, F.6
  • 32
    • 8844227341 scopus 로고    scopus 로고
    • Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals
    • DOI 10.1161/01.RES.0000148637.85595.c5
    • Kazama K, Anrather J, Zhou P, Girouard H, Frys K, Milner TA, et al,. (2004). Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals. Circ Res 95: 1019-1026. (Pubitemid 39532332)
    • (2004) Circulation Research , vol.95 , Issue.10 , pp. 1019-1026
    • Kazama, K.1    Anrather, J.2    Zhou, P.3    Girouard, H.4    Frys, K.5    Milner, T.A.6    Iadecola, C.7
  • 34
    • 0042731701 scopus 로고    scopus 로고
    • Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARγ) in murine primary astrocytes and neurons
    • DOI 10.1046/j.1471-4159.2003.01909.x
    • Klotz L, Sastre M, Kreutz A, Gavrilyuk V, Klockgether T, Feinstein DL, et al,. (2003). Noradrenaline induces expression of peroxisome proliferator activated receptor gamma (PPARgamma) in murine primary astrocytes and neurons. J Neurochem 86: 907-916. (Pubitemid 36988803)
    • (2003) Journal of Neurochemistry , vol.86 , Issue.4 , pp. 907-916
    • Klotz, L.1    Sastre, M.2    Kreutz, A.3    Gavrilyuk, V.4    Klockgether, T.5    Feinstein, D.L.6    Heneka, M.T.7
  • 35
    • 70349980161 scopus 로고    scopus 로고
    • Next generation multifunctional angiotensin receptor blockers
    • Kurtz TW, Klein U, (2009). Next generation multifunctional angiotensin receptor blockers. Hypertens Res 32: 826-834.
    • (2009) Hypertens Res , vol.32 , pp. 826-834
    • Kurtz, T.W.1    Klein, U.2
  • 39
    • 47649122634 scopus 로고    scopus 로고
    • Temporary pretreatment with the angiotensin II type 1 receptor blocker, valsartan, prevents ischemic brain damage through an increase in capillary density
    • Li JM, Mogi M, Iwanami J, Min LJ, Tsukuda K, Sakata A, et al,. (2008). Temporary pretreatment with the angiotensin II type 1 receptor blocker, valsartan, prevents ischemic brain damage through an increase in capillary density. Stroke 39: 2029-2036.
    • (2008) Stroke , vol.39 , pp. 2029-2036
    • Li, J.M.1    Mogi, M.2    Iwanami, J.3    Min, L.J.4    Tsukuda, K.5    Sakata, A.6
  • 40
    • 74949131237 scopus 로고    scopus 로고
    • Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: Prospective cohort analysis
    • Li NC, Lee A, Whitmer RA, Kivipelto M, Lawler E, Kazis LE, et al,. (2010). Use of angiotensin receptor blockers and risk of dementia in a predominantly male population: prospective cohort analysis. BMJ 340: b5465.
    • (2010) BMJ , vol.340
    • Li, N.C.1    Lee, A.2    Whitmer, R.A.3    Kivipelto, M.4    Lawler, E.5    Kazis, L.E.6
  • 43
    • 20444398490 scopus 로고    scopus 로고
    • Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor γ activation
    • DOI 10.1074/jbc.M414390200
    • Luna-Medina R, Cortes-Canteli M, Alonso M, Santos A, Martinez A, Perez-Castillo A, (2005). Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator- activated receptor gamma activation. J Biol Chem 280: 21453-21462. (Pubitemid 40805710)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.22 , pp. 21453-21462
    • Luna-Medina, R.1    Cortes-Canteli, M.2    Alonso, M.3    Santos, A.4    Martinez, A.5    Perez-Castillo, A.6
  • 44
    • 0033496885 scopus 로고    scopus 로고
    • Larger anastomoses in angiotensinogen-knockout mice attenuate early metabolic disturbances after middle cerebral artery occlusion
    • Maeda K, Hata R, Bader M, Walther T, Hossmann KA, (1999). Larger anastomoses in angiotensinogen-knockout mice attenuate early metabolic disturbances after middle cerebral artery occlusion. J Cereb Blood Flow Metab 19: 1092-1098. (Pubitemid 30167759)
    • (1999) Journal of Cerebral Blood Flow and Metabolism , vol.19 , Issue.10 , pp. 1092-1098
    • Maeda, K.1    Hata, R.2    Bader, M.3    Walther, T.4    Hossmann, K.-A.5
  • 46
    • 33745993277 scopus 로고    scopus 로고
    • Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2
    • DOI 10.1161/01.HYP.0000229648.67883.f9, PII 0000426820060700000026
    • Mogi M, Li JM, Iwanami J, Min LJ, Tsukuda K, Iwai M, et al,. (2006). Angiotensin II type-2 receptor stimulation prevents neural damage by transcriptional activation of methyl methanesulfonate sensitive 2. Hypertension 48: 141-148. (Pubitemid 44297536)
    • (2006) Hypertension , vol.48 , Issue.1 , pp. 141-148
    • Mogi, M.1    Li, J.-M.2    Iwanami, J.3    Min, L.-J.4    Tsukuda, K.5    Iwai, M.6    Horiuchi, M.7
  • 47
    • 77958057393 scopus 로고    scopus 로고
    • Irebesratn: Second generation of ARB as Metabosartan
    • Morishita R, Kanda Y, Nakajima M, (2010). Irebesratn: second generation of ARB as Metabosartan. Curr Hypertens Rev 6: 173-179.
    • (2010) Curr Hypertens Rev , vol.6 , pp. 173-179
    • Morishita, R.1    Kanda, Y.2    Nakajima, M.3
  • 48
    • 35748980879 scopus 로고    scopus 로고
    • Pioglitazone exerts protective effects against stroke in stroke-prone spontaneously hypertensive rats, independently of blood pressure
    • DOI 10.1161/STROKEAHA.107.486522, PII 0000767020071100000024
    • Nakamura T, Yamamoto E, Kataoka K, Yamashita T, Tokutomi Y, Dong YF, et al,. (2007). Pioglitazone exerts protective effects against stroke in stroke-prone spontaneously hypertensive rats, independently of blood pressure. Stroke 38: 3016-3022. (Pubitemid 350041562)
    • (2007) Stroke , vol.38 , Issue.11 , pp. 3016-3022
    • Nakamura, T.1    Yamamoto, E.2    Kataoka, K.3    Yamashita, T.4    Tokutomi, Y.5    Dong, Y.-F.6    Matsuba, S.7    Ogawa, H.8    Kim-Mitsuyama, S.9
  • 52
    • 77950472601 scopus 로고    scopus 로고
    • Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB
    • Rompe F, Artuc M, Hallberg A, Alterman M, Ströder K, Thöne-Reineke C, et al,. (2010). Direct angiotensin II type 2 receptor stimulation acts anti-inflammatory through epoxyeicosatrienoic acid and inhibition of nuclear factor kappaB. Hypertension 55: 924-931.
    • (2010) Hypertension , vol.55 , pp. 924-931
    • Rompe, F.1    Artuc, M.2    Hallberg, A.3    Alterman, M.4    Ströder, K.5    Thöne-Reineke, C.6
  • 53
    • 23944500881 scopus 로고    scopus 로고
    • Brain angiotensin II: New developments, unanswered questions and therapeutic opportunities
    • DOI 10.1007/s10571-005-4011-5
    • Saavedra JM, (2005). Brain angiotensin II: new developments, unanswered questions and therapeutic opportunities. Cell Mol Neurobiol 25: 485-512. (Pubitemid 41199709)
    • (2005) Cellular and Molecular Neurobiology , vol.25 , Issue.3-4 , pp. 485-512
    • Saavedra, J.M.1
  • 54
    • 33845538722 scopus 로고    scopus 로고
    • 1 receptor antagonists in the brain
    • DOI 10.1007/s10571-006-9009-0, Proceedings of the 5th International Symposium on Experimental and Clinical Neurobiology, High Tatras, Slovakia, September 2005
    • 1 receptor antagonists in the brain. Cell Mol Neurobiol 26: 1099-1111. (Pubitemid 44924033)
    • (2006) Cellular and Molecular Neurobiology , vol.26 , Issue.7-8 , pp. 1099-1111
    • Saavedra, J.M.1    Benicky, J.2    Zhou, J.3
  • 55
    • 20444427156 scopus 로고    scopus 로고
    • Morbidity and mortality after stroke, eprosartan compared with nitrendipine for secondary prevention: Principal results of a prospective randomized controlled study (MOSES)
    • MOSES Study Group.
    • Schrader J, Lüders S, Kulschewski A, Hammersen F, Plate K, Berger J, et al,.; MOSES Study Group (2005). Morbidity and mortality after stroke, eprosartan compared with nitrendipine for secondary prevention: principal results of a prospective randomized controlled study (MOSES). Stroke 36: 1218-1226.
    • (2005) Stroke , vol.36 , pp. 1218-1226
    • Schrader, J.1    Lüders, S.2    Kulschewski, A.3    Hammersen, F.4    Plate, K.5    Berger, J.6
  • 56
    • 2442451618 scopus 로고    scopus 로고
    • Angiotensin Type 1 Receptor Blockers Induce Peroxisome Proliferator-Activated Receptor-γ Activity
    • DOI 10.1161/01.CIR.0000127955.36250.65
    • Schupp M, Janke J, Clasen R, Unger T, Kintscher U, (2004). Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation 109: 2054-2057. (Pubitemid 38620211)
    • (2004) Circulation , vol.109 , Issue.17 , pp. 2054-2057
    • Schupp, M.1    Janke, J.2    Clasen, R.3    Unger, T.4    Kintscher, U.5
  • 59
    • 0034989969 scopus 로고    scopus 로고
    • Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-γ in vascular smooth muscle cells
    • DOI 10.1210/en.142.7.3125
    • Sugawara A, Takeuchi K, Uruno A, Ikeda Y, Arima S, Kudo M, et al,. (2001). Transcriptional suppression of type 1 angiotensin II receptor gene expression by peroxisome proliferator-activated receptor-gamma in vascular smooth muscle cells. Endocrinology 142: 3125-3134. (Pubitemid 32575551)
    • (2001) Endocrinology , vol.142 , Issue.7 , pp. 3125-3134
    • Sugawara, A.1    Takeuchi, K.2    Uruno, A.3    Ikeda, Y.4    Arima, S.5    Kudo, M.6    Sato, K.7    Taniyama, Y.8    Ito, S.9
  • 60
    • 0035966105 scopus 로고    scopus 로고
    • 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells
    • Takeda K, Ichiki T, Tokunou T, Iino N, Takeshita A, (2001). 15-Deoxy-delta 12,14-prostaglandin J2 and thiazolidinediones activate the MEK/ERK pathway through phosphatidylinositol 3-kinase in vascular smooth muscle cells. J Biol Chem 276: 48950-48955.
    • (2001) J Biol Chem , vol.276 , pp. 48950-48955
    • Takeda, K.1    Ichiki, T.2    Tokunou, T.3    Iino, N.4    Takeshita, A.5
  • 62
    • 70349682174 scopus 로고    scopus 로고
    • Cognitive deficit in amyloid-beta-injected mice was improved by pretreatment with a low dose of telmisartan partly because of peroxisome proliferator-activated receptor-gamma activation
    • Tsukuda K, Mog M, Iwanami J, Min LJ, Sakata A, Jing F, et al,. (2009). Cognitive deficit in amyloid-beta-injected mice was improved by pretreatment with a low dose of telmisartan partly because of peroxisome proliferator- activated receptor-gamma activation. Hypertension 54: 782-787.
    • (2009) Hypertension , vol.54 , pp. 782-787
    • Tsukuda, K.1    Mog, M.2    Iwanami, J.3    Min, L.J.4    Sakata, A.5    Jing, F.6
  • 63
    • 33947204503 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-γ agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents
    • DOI 10.1111/j.1471-4159.2006.04376.x
    • Tureyen K, Kapadia R, Bowen KK, Satriotomo I, Liang J, Feinstein DL, et al,. (2007). Peroxisome proliferator-activated receptor-gamma agonists induce neuroprotection following transient focal ischemia in normotensive, normoglycemic as well as hypertensive and type-2 diabetic rodents. J Neurochem 101: 41-56. (Pubitemid 46426485)
    • (2007) Journal of Neurochemistry , vol.101 , Issue.1 , pp. 41-56
    • Tureyen, K.1    Kapadia, R.2    Bowen, K.K.3    Satriotomo, I.4    Liang, J.5    Feinstein, D.L.6    Vemuganti, R.7
  • 64
    • 0042233718 scopus 로고    scopus 로고
    • Inhibiting angiotensin receptors in the brain: Possible therapeutic implications
    • DOI 10.1185/030079903125001974
    • Unger T, (2003). Inhibiting angiotensin receptors in the brain: possible therapeutic implications. Curr Med Res Opin 19: 449-451. (Pubitemid 36994451)
    • (2003) Current Medical Research and Opinion , vol.19 , Issue.5 , pp. 449-451
    • Unger, T.1
  • 70
    • 0037072826 scopus 로고    scopus 로고
    • Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells
    • Wang N, Verna L, Chen NG, Chen J, Li H, Forman BM, et al,. (2002). Constitutive activation of peroxisome proliferator-activated receptor-gamma suppresses pro-inflammatory adhesion molecules in human vascular endothelial cells. J Biol Chem 277: 34176-34181.
    • (2002) J Biol Chem , vol.277 , pp. 34176-34181
    • Wang, N.1    Verna, L.2    Chen, N.G.3    Chen, J.4    Li, H.5    Forman, B.M.6
  • 71
    • 77955171963 scopus 로고    scopus 로고
    • Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-gamma activation in mice with chronic cerebral hypoperfusion
    • Washida K, Ihara M, Nishio K, Fujita Y, Maki T, Yamada M, et al,. (2010). Nonhypotensive dose of telmisartan attenuates cognitive impairment partially due to peroxisome proliferator-activated receptor-gamma activation in mice with chronic cerebral hypoperfusion. Stroke 41: 1798-1806.
    • (2010) Stroke , vol.41 , pp. 1798-1806
    • Washida, K.1    Ihara, M.2    Nishio, K.3    Fujita, Y.4    Maki, T.5    Yamada, M.6
  • 72
    • 34547637839 scopus 로고    scopus 로고
    • NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat
    • DOI 10.1161/HYPERTENSIONAHA.107.089284, PII 0000426820070800000021
    • Wei Y, Whaley-Connell AT, Chen K, Habibi J, Uptergrove GM, Clark SE, et al,. (2007). NADPH oxidase contributes to vascular inflammation, insulin resistance, and remodeling in the transgenic (mRen2) rat. Hypertension 50: 384-391. (Pubitemid 47205789)
    • (2007) Hypertension , vol.50 , Issue.2 , pp. 384-391
    • Wei, Y.1    Whaley-Connell, A.T.2    Chen, K.3    Habibi, J.4    Uptergrove, G.M.-E.5    Clark, S.E.6    Stump, C.S.7    Ferrario, C.M.8    Sowers, J.R.9
  • 77
    • 0035960634 scopus 로고    scopus 로고
    • Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury
    • Wu L, Iwai M, Nakagami H, Chen R, Suzuki J, Akishita M, et al,. (2001). Roles of angiotensin II type 2 receptor stimulation associated with selective angiotensin II type 1 receptor blockade with valsartan in the improvement of inflammation-induced vascular injury. Circulation 104: 2716-2721. (Pubitemid 33108140)
    • (2001) Circulation , vol.104 , Issue.22 , pp. 2716-2721
    • Wu, L.1    Iwai, M.2    Nakagami, H.3    Li, Z.4    Chen, R.5    Suzuki, J.6    Akishita, M.7    De Gasparo, M.8    Horiuchi, M.9
  • 79
    • 24144475908 scopus 로고    scopus 로고
    • Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation
    • DOI 10.1111/j.1471-4159.2005.03275.x
    • Zhao Y, Foryst-Ludwig A, Bruemmer D, Culman J, Bader M, Unger T, et al,. (2005). Angiotensin II induces peroxisome proliferator-activated receptor gamma in PC12W cells via angiotensin type 2 receptor activation. J Neurochem 94: 1395-1401. (Pubitemid 41232594)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.5 , pp. 1395-1401
    • Zhao, Y.1    Foryst-Ludwig, A.2    Bruemmer, D.3    Culman, J.4    Bader, M.5    Unger, T.6    Kintscher, U.7
  • 81
    • 33646700275 scopus 로고    scopus 로고
    • 1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats
    • DOI 10.1161/01.STR.0000217404.64352.d7, PII 0000767020060500000036
    • 1 receptor blockade regulates the local angiotensin II system in cerebral microvessels from spontaneously hypertensive rats. Stroke 37: 1271-1276. (Pubitemid 43731875)
    • (2006) Stroke , vol.37 , Issue.5 , pp. 1271-1276
    • Zhou, J.1    Pavel, J.2    Macova, M.3    Yu, Z.-X.4    Imboden, H.5    Ge, L.6    Nishioku, T.7    Dou, J.8    Delgiacco, E.9    Saavedra, J.M.10
  • 83
    • 1842453324 scopus 로고    scopus 로고
    • Oxidative stress signalling in Alzheimer's disease
    • DOI 10.1016/j.brainres.2004.01.012, PII S0006899304000770
    • Zhu X, Raina AK, Lee HG, Casadesus G, Smith MA, Perry G, (2004). Oxidative stress signaling in Alzheimer's disease. Brain Res 1000: 32-39. (Pubitemid 38446487)
    • (2004) Brain Research , vol.1000 , Issue.1-2 , pp. 32-39
    • Zhu, X.1    Raina, A.K.2    Lee, H.-G.3    Casadesus, G.4    Smith, M.A.5    Perry, G.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.