AVE0991, a nonpeptide compound, attenuates angiotensin II-induced vascular smooth muscle cell proliferation via induction of heme oxygenase-1 and downregulation of p-38 mapk phosphorylation

International Journal of Hypertension

Volumn 2012, Issue , 2012, Pages

  Chen, Sheng Long ^a   Wu, Yan Xin ^b   Huang, Yi Yi ^b   Fang, Ming ^a   He, Jian Gui ^b   Chen, Yi Li ^b   Xia, Wen Jing ^b   Ma, Hong ^b  

^a GUANGDONG PROVINCIAL PEOPLE'S HOSPITAL   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOTENSIN II; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; ENZYME INHIBITOR; HEME OXYGENASE 1; MITOGEN ACTIVATED PROTEIN KINASE P38; N ETHYLCARBAMOYL 3 [4 (5 FORMYL 4 METHOXY 2 PHENYL 1 IMIDAZOLYLMETHYL)PHENYL] 5 ISOBUTYL 2 THIOPHENESULFONAMIDE; REACTIVE OXYGEN METABOLITE; UNCLASSIFIED DRUG; ZNPPIX;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG ANTAGONISM; DRUG INHIBITION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; INTRACELLULAR SIGNALING; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; RAT; SMOOTH MUSCLE FIBER; VASCULAR SMOOTH MUSCLE;

EID: 84868298825     PISSN: 20900384     EISSN: 20900392     Source Type: Journal    
DOI: 10.1155/2012/958298     Document Type: Article

References (27)

1. Santos R. A. S., Campagnole-Santos M. J., Andrade S. P., Angiotensin-(1-7): an update. Regulatory Peptides 2000 91 13 45 62 2-s2.0-0034725602 10.1016/S0167-0115(00)00138-5
2. Santos R. A. S., Silva A. C. S. E., Maric C., Silva D. M. R., Machado R. P., de Buhr I., Heringer-Walther S., Pinheiro S. V. B., Lopes M. T., Bader M., Mendes E. P., Lemos V. S., Campagnole-Santos M. J., Schultheiss H. P., Speth R., Walther T., Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proceedings of the National Academy of Sciences of the United States of America 2003 100 14 8258 8263 2-s2.0-0037478671 10.1073/pnas. 1432869100 (Pubitemid 36842532)
3. Grobe J. L., Mecca A. P., Lingis M., Shenoy V., Bolton T. A., Machado J. M., Speth R. C., Raizada M. K., Katovich M. J., Prevention of angiotensin II-induced cardiac remodeling by angiotensin-(1-7). American Journal of Physiology 2007 292 2 H736 H742 2-s2.0-33846987938 10.1152/ajpheart.00937.2006
4. Tallant E. A., Clark M. A., Molecular mechanisms of inhibition of vascular growth by angiotensin-(1-7). Hypertension 2003 42 4 574 579 2-s2.0-0141893551 10.1161/01.HYP.0000090322.55782.30 (Pubitemid 37237356)
5. Silva A. C. S. E., Bello A. P. C., Baracho N. C. V., Khosla M. C., Santos R. A. S., marrob@dedalus.lcc.ufmg.br Diuresis and natriuresis produced by long term administration of a selective angiotensin-(1-7) antagonist in normotensive and hypertensive rats. Regulatory Peptides 1998 74 2-3 177 184 10.1016/S0167-0115(98)00038-X (Pubitemid 28288980)
6. Wiemer G., Dobrucki L. W., Louka F. R., Malinski T., Heitsch H., AVE 0991, a nonpeptide mimic of the effects of angiotensin-(1-7) on the endothelium. Hypertension 2002 40 6 847 852 2-s2.0-0036900194 10.1161/01.HYP.0000037979. 53963.8F (Pubitemid 35434905)
7. Lubel J. S., Herath C. B., Tchongue J., Grace J., Jia Z., Spencer K., Casley D., Crowley P., Sievert W., Burrell L. M., Angus P. W., Angiotensin-(1-7), an alternative metabolite of the renin-angiotensin system, is up-regulated in human liver disease and has antifibrotic activity in the bile-duct-ligated rat. Clinical Science 2009 117 11 375 386 2-s2.0-67651192493 10.1042/CS20080647
8. Ferreira A. J., Oliveira T. L., Castro M. C. M., Almeida A. P., Castro C. H., Caliari M. V., Gava E., Kitten G. T., Santos R. A. S., Isoproterenol- induced impairment of heart function and remodeling are attenuated by the nonpeptide angiotensin-(1-7) analogue AVE 0991. Life Sciences 2007 81 11 916 923 2-s2.0-34548507186 10.1016/j.lfs.2007.07.022 (Pubitemid 47374211)
9. Anderson P. W., Do Y. S., Hsueh W. A., Angiotensin II causes mesangial cell hypertrophy. Hypertension 1993 21 1 29 35 2-s2.0-0027441526 (Pubitemid 23006449)
10. Yaghini F. A., Song C. Y., Lavrentyev E. N., Ghafoor H. U. B., Fang X. R., Estes A. M., Campbell W. B., Malik K. U., Angiotensin II-induced vascular smooth muscle cell migration and growth are mediated by cytochrome p450 1b1-dependent superoxide generation. Hypertension 2010 55 6 1461 1467 2-s2.0-77953124375 10.1161/HYPERTENSIONAHA.110.150029
11. Ohtsu H., Suzuki H., Nakashima H., Dhobale S., Frank G. D., Motley E. D., Eguchi S., Angiotensin II signal transduction through small GTP-binding proteins: mechanism and significance in vascular smooth muscle cells. Hypertension 2006 48 4 534 540 2-s2.0-33750602514 10.1161/01.HYP.0000237975. 90870.eb (Pubitemid 44843847)
12. Kranzhöfer R., rogerkranzhoefer@med.uni-heidelberg.de Schmidt J., Pfeiffer C. A. H., Hagl S., Libby P., Kübler W., Angiotensin induces inflammatory activation of human vascular smooth muscle cells. Arteriosclerosis, Thrombosis, and Vascular Biology 1999 19 7 1623 1629 (Pubitemid 29323820)
13. New L., Han J., The p38 MAP kinase pathway and its biological function. Trends in Cardiovascular Medicine 1998 8 5 220 229 2-s2.0-0031817208 10.1016/S1050-1738(98)00012-7 (Pubitemid 28345826)
14. Otterbein L. E., Choi A. M. K., Heme oxygenase: colors of defense against cellular stress. American Journal of Physiology 2000 279 6 L1029 L1037 2-s2.0-0034529932 (Pubitemid 32009488)
15. Hill-Kapturczak N., Voakes C., Garcia J., Visner G., Nick H. S., Agarwal A., A cis-acting region regulates oxidized lipid-mediated induction of the human heme oxygenase-1 gene in endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology 2003 23 8 1416 1422 2-s2.0-0042734437 10.1161/01.ATV. 0000081656.76378.A7 (Pubitemid 36994531)
16. Togane Y., Morita T., Suematsu M., Ishimura Y., Yamazaki J. I., Katayama S., Protective roles of endogenous carbon monoxide in neointimal development elicited by arterial injury. American Journal of Physiology 2000 278 2 H623 H632 2-s2.0-0034063826 (Pubitemid 30131264)
17. Morita T., Imai T., Sugiyama T., Katayama S., Yoshino G., Heme oxygenase-1 in vascular smooth muscle cells counteracts cardiovascular damage induced by angiotensin II. Current Neurovascular Research 2005 2 2 113 120 2-s2.0-18744410090 10.2174/1567202053586848 (Pubitemid 40676619)
18. Sun J. J., Kim H. J., Seo H. G., Lee J. H., Yun-Choi H. S., Chang K. C., YS 49, 1-(α -naphtylmethyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, regulates angiotensin II-stimulated ROS production, JNK phosphorylation and vascular smooth muscle cell proliferation via the induction of heme oxygenase-1. Life Sciences 2008 82 11-12 600 607 2-s2.0-39649096541 10.1016/j.lfs.2007.12. 015
19. Freeman E. J., Chisolm G. M., Ferrario C. M., Tallant E. A., Angiotensin-(1-7) inhibits vascular smooth muscle cell growth. Hypertension 1996 28 1 104 108 2-s2.0-0029957780 (Pubitemid 26231097)
20. Hu C. M., Chen Y. H., Chiang M. T., Chau L. Y., Heme oxygenase-1 inhibits angiotensin II-induced cardiac hypertrophy in vitro and in vivo. Circulation 2004 110 3 309 316 2-s2.0-3242661655 10.1161/01.CIR.0000135475.35758.23 (Pubitemid 38955500)
21. He J. G., Chen S. L., Huang Y. Y., Chen Y. L., Dong Y. G., Ma H., The nonpeptide AVE0991 attenuates myocardial hypertrophy as induced by angiotensin II through downregulation of transforming growth factor- β 1/Smad2 expression. Heart and Vessels 2010 25 5 438 443 2-s2.0-77956030116 10.1007/s00380-009-1213-7
22. Li Y., Wu J., He Q., Shou Z., Zhang P., Pen W., Zhu Y., Chen J., Angiotensin (1-7) prevent heart dysfunction and left ventricular remodeling caused by renal dysfunction in 5/6 nephrectomy mice. Hypertension Research 2009 32 5 369 374 2-s2.0-68249153570 10.1038/hr.2009.25
23. Baker K. M., Aceto J. F., Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. American Journal of Physiology 1990 259 2 H610 H618 2-s2.0-0025126437 (Pubitemid 20259440)
24. Gray M. O., Long C. S., Kalinyak J. E., Li H. T., Karliner J. S., Angiotensin II stimulates cardiac myocyte hypertrophy via paracrine release of TGF- β1 and endothelin-1 from fibroblasts. Cardiovascular Research 1998 40 2 352 363 10.1016/S0008-6363(98)00121-7 (Pubitemid 28506046)
25. Herbert K. E., Mistry Y., Hastings R., Poolman T., Niklason L., Williams B., Angiotensin II-mediated oxidative DNA damage accelerates cellular senescence in cultured human vascular smooth muscle cells via telomere-dependent and independent pathways. Circulation Research 2008 102 2 201 208 2-s2.0-41149139491 10.1161/CIRCRESAHA.107.158626 (Pubitemid 351651124)
26. Robinson M. J., Cobb M. H., Mitogen-activated protein kinase pathways. Current Opinion in Cell Biology 1997 9 2 180 186 2-s2.0-0030898417 10.1016/S0955-0674(97)80061-0 (Pubitemid 27135985)
27. Lin Y. T., Chen Y. H., d810070@cc.kmu.edu.tw Yang Y. H., Jao H. C., Abiko Y., Yokoyama K., Hsu C., chinhsu@kmu.edu.tw Heme oxygenase-1 suppresses the infiltration of neutrophils in rat liver during sepsis through inactivation of p38 MAPK. Shock 2010 34 6 615 621 10.1097/SHK.0b013e3181e46ee0