Immunofluorescence localization of the receptor Mas in cardiovascular- related areas of the rat brain

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 3, 2007, Pages

  Becker, Lenice K ^a   Etelvino, Gisele M ^a   Walther, Thomas ^b   Santos, Robson A S ^a   Campagnole Santos, Maria J ^a  

^a FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

Angiotensin (1 7); Hypothalamus; Medulla

Indexed keywords

FLUORESCENT DYE; PROTEIN MAS; RECEPTOR PROTEIN; RHODAMINE; UNCLASSIFIED DRUG;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; BRAIN CORTEX; BRAIN REGION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; FOREBRAIN; HIPPOCAMPUS; HYPOGLOSSAL NUCLEUS; IMMUNOFLUORESCENCE; IMMUNOREACTIVITY; INFERIOR OLIVE; MAGNOCELLULAR NUCLEUS; MALE; MEDULLA OBLONGATA; NONHUMAN; PREOPTIC AREA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SUPRAOPTIC NUCLEUS; THALAMUS NUCLEUS; WISTAR RAT;

ANGIOTENSIN I; ANIMALS; BRAIN; CARDIOVASCULAR PHYSIOLOGY; NEURONS; PEPTIDE FRAGMENTS; PROTO-ONCOGENE PROTEINS; RATS; RECEPTORS, G-PROTEIN-COUPLED;

EID: 34548398570     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.00141.2007     Document Type: Article

References (40)

1. Alzamora AC, Santos RAS, Campagnole-Santos MJ. Hypotensive effect of ANG II and ANG-(1-7) at the caudal ventrolateral medulla involves different mechanisms. Am J Physiol Regul Integr Comp Physiol 283: R1187-R1195, 2002.
2. Ambühl P, Felix D, Imboden H, Khosla MC, Ferrario CM. Effects of angiotensin analogues and angiotensin receptor antagonists on paraventricular neurones. Regul Pept 38: 111-120, 1992.
3. Ambühl P, Felix D, Khosla MC. [7-D-ALA]-angiotensin- (1-7): selective antagonism of angiotensin-(1-7) in the rat paraventricular nucleus. Brain Res Bull 35: 289-291, 1994.
4. Block CH, Santos RAS, Brosnihan KB, Ferrario CM. Immunocytochemical localization of angiotensin-(1-7) in the rat forebrain. Peptides 9: 1395-1401, 1988.
5. Bunnemann B, Fuxe K, Ganten D. The brain renin-angiotensin system: localization and general significance. J Cardiovasc Pharmacol 19, Suppl 6: S51-S62, 1992.
6. Bunnemann B, Fuxe K, Metzger R, Mullins J, Jackson TR, Hanley MR, Ganten D. Autoradiographic localization of mas proto-oncogene mRNA in adult rat brain using in situ hybridization. Neurosci Lett 114: 147-153, 1990.
7. Campagnole-Santos MJ, Diz DI, Santos RAS, Kholsa MC, Brosniham KB, Ferrario CM. Cardiovascular effects of angiotensin-(1-7) injected into the dorsal medulla of rats. Am J Physiol Heart Circ Physiol 257: H324-H329, 1989.
8. Campagnole-Santos MJ, Heringer SB, Batista EN, Khosla MC, Santos RAS. Differential baroreceptor reflex modulation by centrally infused angiotensin peptides. Am J Physiol Regul Integr Comp Physiol 263: R89-R94, 1992.
9. 2 receptors in the mouse heart. Hypertension 46: 937-942, 2005.
10. Chaves GZ, Caligiorne SM, Santos RAS, Khosla MC, Campagnole-Santos MJ. Modulation of the baroreflex control of heart rate by angiotensin-(1-7) at the nucleus tractus solitarii of normotensive and spontaneously hypertensive rats. J Hypertens 18: 1841-1848, 2000.
11. Crackower MA, Oudit GY, Kozieradzki I, Sarao R, Sun H, Sasaki T, Hirsch E, Suzuki A, Shioi T, Irie-Sasaki J, Sah R, Cheng HY, Rybin VO, Lembo G, Fratta L, Oliveira-dos-Santos AJ, Benovic JL, Kahn CR, Izumo S, Steinberg SF, Wymann MP, Backx PH, Penninger JM. Angiotensin-converting enzyme 2 is an essential regulator of heart function. Nature 417: 822-828, 2002.
12. Donoghue M, Hsieh F, Baronas E, Godbout K, Gosselin M, Stagliano N, Donovan M, Woolf B, Robison K, Jeyaseelan R, Breitbart RE, Acton S. A novel angiotensin-converting enzyme-related carboxypeptidase (ACE2) converts angiotensin I to angiotensin-1-9. Circ Res 87: 1-9, 2000.
13. Faria-Silva R, Duarte FV, Santos RAS. Short-term angiotensin(1-7) receptor Mas stimulation improves endothelial function in normotensive rats. Hypertension 46: 948-952, 2005.
14. Ferreira AJ, Jacoby BA, Araujo CA, Macedo FA, Silva GA, Almeida AP, Caliari MV, Santos RAS. The nonpeptide angiotensin-(1-7) receptor Mas agonist AVE 0991 attenuates heart failure induced by myocardial infarction. Am J Physiol Heart Circ Physiol 292: H1113-H1119, 2007.
15. Fontes MAP, Silva LCS, Campagnole-Santos MJ, Khosla MC, Guertzenstein PG, Santos RAS. Evidence that angiotensin-(1-7) plays a role in the central control of blood pressure at the ventrolateral medulla acting through specific receptors. Brain Res 665: 175-180, 1994.
16. Gironacci MM, Valera MS, Yujnovsky I, Pena C. Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats. Hypertension 44: 783-787, 2004.
17. Gironacci MM, Vatta M, Rodriguez-Fermepin M, Fernandez BE, Pena C. Angiotensin-(1-7) reduces norepinephrine release through a nitric oxide mechanism in rat hypothalamus. Hypertension 35: 1248-1252, 2000.
18. Hellner K, Walther T, Schubert M, Albrecht D. Angiotensin-(1-7) enhances LTP in the hippocampus through the G-protein-coupled receptor Mas. Mol Cell Neurosci 29: 427-435, 2005.
19. Heringer-Walther S, Batista EN, Walther T, Khosla MC, Santos RAS, Campagnole-Santos MJ. Baroreflex improvement in SHR after ACE inhibition involves angiotensin-(1-7). Hypertension 37: 1309-1314, 2001.
20. Holy Z, Braszko J, Kuprvszewski G, Witczuk B, Wisniewski K. Angiotensin II derived peptides devoid of phenylalanine in position 8 have full psychotropic activity of the parent hormone. J Physiol Pharmacol 43: 183-192, 1992.
21. Lavoie JL, Cassel MD, Gross KW, Sigmund CD. Adjacent expression of rennin and angiotensinogen in the rostral ventrolateral medulla using a dual-reporter transgenic model. Hypertension 43: 1116-1119, 2004.
22. Lemos VS, Silva DM, Walther T, Alenina N, Bader M, Santos RAS. The endothelium-dependent vasodilator effect of the nonpeptide Ang(1-7) mimic AVE 0991 is abolished in the aorta of Mas-knockout mice. J Cardiovasc Pharmacol 46: 274-279, 2005.
23. Lynch KR, Hawelu-Johnson CL, Guyenet PG. Localization of brain angiotensinogen mRNA by hybridization histochemistry. Brain Res 388: 149-158, 1987.
24. Metzger R, Bader M, Ludwig T, Berberich C, Bunnemann B, Ganten D. Expression of the mouse and rat mas proto-oncogene in the brain and peripheral tissues. FEBS Lett 357: 27-32, 1995.
25. Paxinos G, Watson C. The rat brain in stereotaxic coordinates (2nd ed.). New York: Academic, 1986.
26. Pinheiro SV, Simões e Silva AC, Sampaio WO, de Paula RD, Mendes EP, Bontempo ED, Pesquero JB, Walther T, Alenina N, Bader M, Bleich M, Santos RAS. Nonpeptide AVE 0991 is an angiotensin-(1-7) receptor Mas agonist in the mouse kidney. Hypertension 44: 490-496, 2004.
27. Qadri F, Wolf A, Waldmann T, Rascher W, Unger T. Sensitivity of hypothalamic paraventricular nucleus to C- and N-terminal angiotensin fragments: vasopressin release and drinking. J Neuroendocrinol 10: 275-281, 1998.
28. Rioux JP, Bouhnik J, Clauser E, Corvol P. The renin-angiotensin system in the rat brain. Immunocytochemical localization of angiotensinogen in glial cells and neurons. Histochemistry 89: 323-331, 1988.
29. Sampaio WO, Santos RAS, Faria-Silva R, Machado LTM, Schiffrin EL, Touyz RM. Angiotensin-(1-7) through receptor mas mediates endothelial nitric oxide synthase activation via Akt-dependent pathways. Hypertension 49: 185-192, 2007.
30. Santos RAS, Ferreira AJ, Pinheiro SV, Sampaio WO, Touyz RM, Campagnole-Santos MJ. Angiotensin-(1-7) and its receptor as a potential targets for new cardiovascular drugs. Expert Opin Investig Drugs 14: 1019-1031, 2005.
31. Santos RAS, Campagnole-Santos MJ, Andrade SP. Angiotensin-(1-7): an update. Regul Pept 9: 45-62, 2000.
32. Santos RAS, Campagnole-Santos MJ, Baracho NC, Fontes MAP, Silva LC, Neves LA, Oliveira DR, Caligiorne SM, Rodrigues AR, Gropen Junior C, Carvalho WS, Silva ACS, Khosla MC. Characterization of a new angiotensin antagonist selective for angiotensin-(1-7): evidence that the actions of angiotensin-(1-7) are mediated by specific angiotensin receptors. Brain Res Bull 35: 293-298, 1994.
33. Santos RAS, Simoes e Silva AC, Maric C, Silva DM, Machado RP, de Buhr I, Heringer-Walther S, Pinheiro SV, Lopes MT, Bader M, Mendes EP, Lemos VS, Campagnole-Santos MJ, Schultheiss HP, Speth R, Walther T. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Proc Natl Acad Sci USA 100: 8258-8263, 2003.
34. Schiavone MT, Santos RAS, Brosnihan KB, Khosla MC, Ferrario CM. Release of vasopressin from the hypothalamo-neurohypophysial system by angiotensin-(1-7) heptapeptide. Proc Natl Acad Sci USA 85: 4095-4098, 1988.
35. Silva AQG, Santos RAS, Fontes MAP. Blockade of endogenous angiotensin-(1-7) in the hypothalamic paraventricular nucleus reduces renal sympathetic tone. Hypertension 46: 1-8, 2005.
36. Silva DM, Vianna HR, Cortes SF, Campagnole-Santos MJ, Santos RAS, Lemos VS. Evidence for a new angiotensin-(1-7) receptor subtype in the aorta of Sprague-Dawley rats. Peptides 28: 702-707, 2007.
37. Tipnis SR, Hooper NM, Hyde R, Karran E, Christie G, Turner AJ. A human homolog of angiotensin-converting enzyme. Cloning and functional expression as a captopril-insensitive carboxypeptidase. J Biol Chem 275: 33238-33243, 2000.
38. Vickers C, Hales P, Kaushik V. Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase. J Biol Chem 277: 14838-14843, 2002.
39. 1 receptor in the amygdala. J Neurophysiol 83: 2012-2021, 2000.
40. Walther T, Balschun D, Voigt JP, Fink H, Zuschratter W, Birchmeier C, Ganten D, Bader M. Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene. J Biol Chem 273: 11867-11873, 1998.