Angiotensin-(1-7) upregulates central nitric oxide synthase in spontaneously hypertensive rats

Brain Research

Volumn 1453, Issue , 2012, Pages 1-7

  Cerrato, Bruno D ^a   Frasch, Alejandra P ^a   Nakagawa, Pablo ^a   Longo Carbajosa, Nadia ^a   Peña, Clara ^a   Höcht, Cristian ^a   Gironacci, Mariela M ^a  

^a UNIVERSIDAD DE BUENOS AIRES   (Argentina)

Author keywords

Angiotensin (1 7); Hypertension; Hypothalamus; Nitric oxide synthase

Indexed keywords

ANGIOTENSIN[1-7]; ARGININE; CITRULLINE; NITRIC OXIDE SYNTHASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTERIOR HYPOTHALAMUS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; HYPERTENSION; HYPOTHALAMUS; MEAN ARTERIAL PRESSURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; UPREGULATION; WESTERN BLOTTING;

ANGIOTENSIN I; ANIMALS; BLOOD PRESSURE; HYPERTENSION; HYPOTHALAMUS; MALE; NITRIC OXIDE SYNTHASE TYPE I; PEPTIDE FRAGMENTS; RATS; RATS, INBRED SHR; RATS, INBRED WKY; UP-REGULATION;

RATTUS;

EID: 84859804254     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2012.03.022     Document Type: Article

References (38)

1. Costa, M.A., López Verrilli, M.A., Gomez, K., Nakagawa, P., Peña, C., Arranz, C., Gironacci, M.M., 2010. Angiotensin-(1-7) upregulates cardiac nitric oxide synthase in spontaneously hypertensive rats. Am. J. Physiol. Heart Circ. Physiol. 299, H1205-H1211.
2. +-ATPase by Ang-(1-7). Biochem. J. 395, 183-190.
3. Feng, Y., Xia, H., Cai, Y., Halabi, C.M., Becker, L.K., Santos, R.A.S., Speth, R.C., Sigmund, C.D., Lazartigues, E., 2010. Brain-selective overexpression of human angiotensin-converting enzyme type 2 attenuates neurogenic hypertension. Circ. Res. 106, 373-382.
4. Ferrario, C.M., Ahmad, S., Joyner, J., Varagic, J., 2010. Advances in the renin angiotensin system focus on angiotensin-converting enzyme 2 and angiotensin-(1-7). Adv. Pharmacol. 59, 197-233.
5. Ferreira, A.J., Santos, R.A.S., Bradford, C.N., Mecca, C.N., Sumners, C., Katovich, M.J., Raizada, M.K., 2010. Therapeutic implications of the vasoprotective axis of the renin-angiotensin systemin cardiovascular diseases. Hypertension 55, 207-213.
6. Garcia, N.H., Garvin, J.L., 1994. Angiotensin-(1-7) has a biphasic effect on fluid absorption in the proximal straight tubule. J. Am. Soc. Nephrol. 5, 1133-1138. (Pubitemid 24977092)
7. Gironacci, M.M., Coba, M., Peña, C., 1999. Angiotensin-(1-7) binds at the type 1 angiotensin II receptors in rat renal cortex. Regul. Pept. 84, 51-54. (Pubitemid 29434105)
8. Gironacci, M.M., Vatta,M., Rodriguez-Fermepín,M., Fernández, B.E., Peña, C., 2000. Angiotensin-(1-7) reduces norepinephrine release through a nitric oxide mechanism in rat hypothalamus. Hypertension 35, 1248-1252. (Pubitemid 30413659)
9. Gironacci, M.M., Valera, M.S., Yujnovsky, I., Peña, C., 2004a. Angiotensin-(1-7) inhibitory mechanism of norepinephrine release in hypertensive rats. Hypertension 44, 783-787. (Pubitemid 39435254)
10. Gironacci, M.M., Yujnovsky, I., Gorzalczany, S., Taira, C., Peña, C., 2004b. Angiotensin-(1-7) inhibits the angiotensin II-enhanced norepinephrine release in coarcted hypertensive rats. Regul. Pept. 118, 45-49. (Pubitemid 38167366)
11. Glickman, M.H., Ciechanover, A., 2002. The ubiquitin-proteasome proteolytic pathway. Physiol. Rev. 82, 373-428.
12. Haulica, I., Bild,W., Mihaila, C.N., Ionita, T., Boisteanu, C.P., Neagu, B., 2003. Biphasic effects of angiotensin (1-7) and its interactions with angiotensin II in rat aorta. J. Renin Angiotensin Aldosterone Syst. 4, 124-128. (Pubitemid 36790185)
13. Häuser, W., Sassmann, A., Qadri, F., Jöhren, O., Dominiak, P., 2005. Expression of nitric oxide synthase isoforms in hypothalamopituitary- adrenal axis during the development of spontaneous hypertension in rats. Mol. Brain Res. 18, 198-204. (Pubitemid 41138039)
14. Höcht, C., Opezzo, J.A.W., Gironacci, M.M., Peña, C., Taira, C.A., 2006. Hypothalamic cardiovascular effects of angiotensin-(1-7) in spontaneously hypertensive rats. Regul. Pept. 135, 39-44. (Pubitemid 43816100)
15. Höcht, C., Gironacci, M.M., Mayer, M.A., Schuman, M., Bertera, F.M., Taira, C.A., 2008. Involvement of angiotensin-(1-7) in the hypothalamic hypotensive effect of captopril in sinoaortic denervated rats. Regul. Pept. 146, 58-66.
16. Hojná, S., Kuneš, J., Zicha, J., 2010. Alterations of NO synthase isoforms in brain and kidney of rats with genetic and salt hypertension. Physiol. Res. 59, 997-1009.
17. Krukoff, T.L., 1999. Central actions of nitric oxide in regulation of autonomic function. Brain Res. Rev. 30, 52-65. (Pubitemid 29331515)
18. Li, Y.F., Wang, Y., Channon, K.M., Schultz, H.D., Zucker, I.H., Patel, K.P., 2005. Manipulation of neuronal nitric oxide synthase within the paraventricular nucleus using adenovirus and antisense technology. Methods Mol. Med. 112, 59-79.
19. 2receptors mediates tyrosine hydroxylase degradation via the ubiquitin-proteasome pathway. J. Neurochem. 109, 326-335.
20. Lopez Verrilli, M.A., Rodriguez Fermepín, M., Longo Carbajosa, N., Landa, S., Cerrato, B.D., García, S., Gironacci, M.M., 2012. Angiotensin-(1-7) through Mas receptor upregulates neuronal norepinephrine transporter via Akt And Erk1/2-dependent pathways. J. Neurochem. 120, 46-55.
21. Luo, C., Zhu, D., 2011. Research progress on neurobiology of neuronal nitric oxide synthase. Neurosci. Bull. 27, 23-35.
22. Mastelari, R.B., de Souza, H.C., Lenhard, A., de Aguiar Corrêa, F.M., Martins-Pinge, M.C., 2011. Nitric oxide inhibition in paraventricular nucleus on cardiovascular and autonomic modulation after exercise training in unanesthetized rats. Brain Res. 1375, 68-76.
23. Moncada, S., Higgs, E.A., 2006. The discovery of nitric oxide and its role in vascular biology. Br. J. Pharmacol. 147 (Suppl. 1), S193-S201. (Pubitemid 43077277)
24. Musial, A., Eissa, N.T., 2011. Inducible nitric oxide synthase is regulated by the proteasome degradation pathway. J. Biol. Chem. 276, 24268-24273.
25. Osawa, Y., Lowe, E.R., Everett, A.C., Dunbar, A.Y., Billecke, S.S., 2003. Proteolytic degradation of nitric oxide synthase: effect of inhibitors and role of hsp-90 based chaperones. J. Pharmacol. Exp. Ther. 304, 493-497. (Pubitemid 36152322)
26. Patel, K.P., Li, Y., Hirooka, Y., 2001. Role of nitric oxide in central sympathetic outflow. Exp. Biol. Med. 226, 814-824. (Pubitemid 34053230)
27. Paxinos, G., Watson, C.H., 2007. The Rat Brain in Stereotaxic Coordinates, 6th edn. Academic Press, New York.
28. Plochocka-Zulinska, D., Krukoff, T.L., 1997. Increased gene expression of neuronal nitric oxide synthase in brain of adult spontaneously hypertensive rats. Mol. Brain Res. 48, 291-297. (Pubitemid 27390065)
29. Qadri, F., Arens, T., Schwarz, E.C., Häuser, W., Dendorfer, A., Dominiak, P., 2003. Brain nitric oxide synthase activity in spontaneously hypertensive rats during the development of hypertension. J. Hypertens. 21, 1687-1694. (Pubitemid 37076352)
30. Rowe, B.P., Saylor, D.L., Speth, R.C., Absher, D.R., 1995. Angiotensin (1-7) binding at angiotensin II receptors in the rat brain. Regul. Pept. 56, 139-146.
31. Stangl, V., Lorenz, M., Meiners, S., Ludwig, A., Bartsch, C., Moobed, M., Vietzke, A., Kinkel, H.T., Baumann, G., Stangl, K., 2004. Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway. FASEB J. 18, 272-279. (Pubitemid 38186246)
32. Török, J., 2008. Participation of nitric oxide in different models of experimental hypertension. Physiol. Res. 57, 813-825.
33. Ueda, S., Masumori-Maemoto, S., Ashino, K., Nagahara, T., Gotoh, E., Umemura, S., Ishii, M., 2000. Angiotensin-(1-7) attenuates vasoconstriction evoked by angiotensin II but not by noradrenaline in man. Hypertension 35, 998-1001. (Pubitemid 30303964)
34. Veersingham, S.J., Raizada, M.K., 2003. Brain renin-angiotensin system in hypertension. Br. J. Pharmacol. 139, 191-202.
35. Wyss, J.M., Carlson, S.H., 1999. The role of the central nervous system in hypertension. Curr. Hypertens. Rep. 1, 246-253.
36. Xiao, L., Gao, L., Lazartigues, E., Zucker, I.H., 2011. Brain-selective overexpression of angiotensin-converting enzyme 2 attenuates sympathetic nerve activity and enhances baroreflex function in chronic heart failure. Hypertension 58, 1057-1065.
37. Xu, P., Sriramula, S., Lazartigues, E., 2011. ACE2/Ang-(1-7)/Mas pathway in the brain: the axis of good. Am. J. Physiol. Regul. Integr. Comp. Physiol. 300, R804-R817.
38. Zhang, Y., Lu, J., Shi, J., Lin, X., Dong, J., Zhang, S., Liu, Y., Tong, Q., 2008. Central administration of angiotensin-(1-7) stimulates nitric oxide release and upregulates the endothelial nitric oxide synthase expression following focal cerebral ischemia/reperfusion in rats. Neuropeptides 42, 593-600.