Brain-selective overexpression of human angiotensin-converting enzyme type 2 attenuates neurogenic hypertension

Circulation Research

Volumn 106, Issue 2, 2010, Pages 373-382

  Feng, Yumei ^a   Xia, Huijing ^a   Cai, Yanhui ^a   Halabi, Carmen M ^c   Becker, Lenice K ^d   Santos, Robson A S ^d   Speth, Robert C ^e   Sigmund, Curt D ^c   Lazartigues, Eric ^a,b  

^a Department of Pharmacology and Experimental Therapeutics ^*  (United States)

^b LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

^d FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^e NOVA SOUTHEASTERN UNIVERSITY   (United States)

Author keywords

Autonomic function; Baroreflex; Blood pressure; Carboxypeptidase; Nitric oxide

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN 2 RECEPTOR; ANGIOTENSIN CONVERTING ENZYME 2; ANGIOTENSIN RECEPTOR; ANGIOTENSIN[1-7][7 DEXTRO ALANINE]; BETA ACTIN; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; SYNAPSIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD PRESSURE REGULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; HEMODYNAMIC PARAMETERS; HYPERTENSION; MALE; MOUSE; NONHUMAN; PARASYMPATHETIC TONE; PRESSORECEPTOR REFLEX; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; TELEMETRY; TRANSGENIC MOUSE;

ANGIOTENSIN II; ANIMALS; BAROREFLEX; BLOOD PRESSURE; BLOTTING, WESTERN; BRAIN; BRAIN STEM; FEMALE; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PARASYMPATHETIC NERVOUS SYSTEM; PEPTIDE FRAGMENTS; PEPTIDYL-DIPEPTIDASE A; RECEPTORS, ANGIOTENSIN; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 76349095332     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.109.208645     Document Type: Article

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