Predicting drug efficacy using integrative models for chronic respiratory diseases

Inflammation and Allergy - Drug Targets

Volumn 12, Issue 2, 2013, Pages 124-131

  Stevenson, Christopher S ^a,b,c,d   Sridhar, Sriram ^a   Phillips, Jonathan E ^a  

^a HOFFMANN LA ROCHE INC   (United States)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^c UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^d NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

Animal models; Asthma; Bioinformatics; COPD; IPF; Lung physiology; Respiratory disease; Translational research

Indexed keywords

ALUMINUM HYDROXIDE; ANTIGEN; BLEOMYCIN; CIGARETTE SMOKE; INTERLEUKIN 5; LEBRIKIZUMAB; TRANSCRIPTION FACTOR RUNX2;

AIRWAY REMODELING; ARTICLE; ASTHMA; BIOINFORMATICS; BRONCHOSPASM; CHRONIC OBSTRUCTIVE LUNG DISEASE; CHRONIC RESPIRATORY TRACT DISEASE; DRUG DEVELOPMENT; DRUG EFFICACY; DRUG INDUSTRY; DRUG SENSITIZATION; FIBROSING ALVEOLITIS; FIBROSIS; GENE EXPRESSION; HUMAN; IN VIVO STUDY; LUNG FUNCTION; LUNG LAVAGE; NONHUMAN; PHARMACOKINETICS; PHASE 2 CLINICAL TRIAL (TOPIC); PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL (TOPIC);

ANIMALS; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HUMANS; RESPIRATORY TRACT DISEASES;

EID: 84876702936     PISSN: 18715281     EISSN: None     Source Type: Journal    
DOI: 10.2174/1871528111312020006     Document Type: Article

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