-
1
-
-
36348981219
-
Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation
-
(2007), 10.1152/ajplung.00105.2007, 17720875
-
Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K. Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation. Am J Physiol Lung Cell Mol Physiol 2007, 293:L1183-L1193. (2007), 10.1152/ajplung.00105.2007, 17720875.
-
(2007)
Am J Physiol Lung Cell Mol Physiol
, vol.293
-
-
Stevenson, C.S.1
Docx, C.2
Webster, R.3
Battram, C.4
Hynx, D.5
Giddings, J.6
Cooper, P.R.7
Chakravarty, P.8
Rahman, I.9
Marwick, J.A.10
Kirkham, P.A.11
Charman, C.12
Richardson, D.L.13
Nirmala, N.R.14
Whittaker, P.15
Butler, K.16
-
2
-
-
65249151877
-
Inhibition of PI3K{delta} Restores Glucocorticoid Function in Smoking-induced Airway Inflammation in Mice
-
10.1164/rccm.200810-1570OC, 19164702
-
Marwick JA, Caramori G, Stevenson CC, Casolari P, Jazrawi E, Barnes PJ, Ito K, Adcock IM, Kirkham PA, Papi A. Inhibition of PI3K{delta} Restores Glucocorticoid Function in Smoking-induced Airway Inflammation in Mice. Am J Respir Crit Care Med 2009, 179:542-548. 10.1164/rccm.200810-1570OC, 19164702.
-
(2009)
Am J Respir Crit Care Med
, vol.179
, pp. 542-548
-
-
Marwick, J.A.1
Caramori, G.2
Stevenson, C.C.3
Casolari, P.4
Jazrawi, E.5
Barnes, P.J.6
Ito, K.7
Adcock, I.M.8
Kirkham, P.A.9
Papi, A.10
-
3
-
-
0025609659
-
Cigarette smoke causes physiologic and morphologic changes of emphysema in the guinea pig
-
Wright JL, Churg A. Cigarette smoke causes physiologic and morphologic changes of emphysema in the guinea pig. Am Rev Respir Dis 1990, 142:1422-1428.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 1422-1428
-
-
Wright, J.L.1
Churg, A.2
-
4
-
-
33646585181
-
Differential protease, innate immunity and NFkB induction profiles during lung inflammation induced by sub-chronic cigarette smoke exposure in mice
-
10.1152/ajplung.00201.2005, 16361358
-
Vlahos R, Bozinovski S, Jones JE, Powell J, Gras J, Lilja A, Hansen MJ, Gualano RC, Irving L, Anderson GP. Differential protease, innate immunity and NFkB induction profiles during lung inflammation induced by sub-chronic cigarette smoke exposure in mice. Am J Physiol Lung Cell Mol Physiol 2006, 290:L931-L945. 10.1152/ajplung.00201.2005, 16361358.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Vlahos, R.1
Bozinovski, S.2
Jones, J.E.3
Powell, J.4
Gras, J.5
Lilja, A.6
Hansen, M.J.7
Gualano, R.C.8
Irving, L.9
Anderson, G.P.10
-
5
-
-
0037106511
-
Tumor necrosis factor-alpha is central to acute cigarette smoke-induced inflammation and connective tissue breakdown
-
10.1164/rccm.200202-097OC, 12231496
-
Churg A, Dai J, Tai H, Xie C, Wright JL. Tumor necrosis factor-alpha is central to acute cigarette smoke-induced inflammation and connective tissue breakdown. Am J Respir Crit Care Med 2002, 166:849-854. 10.1164/rccm.200202-097OC, 12231496.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 849-854
-
-
Churg, A.1
Dai, J.2
Tai, H.3
Xie, C.4
Wright, J.L.5
-
6
-
-
4444322565
-
Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse
-
10.1164/rccm.200404-511OC, 15184206
-
Churg A, Wang RD, Tai H, Wang X, Xie C, Wright JL. Tumor necrosis factor-alpha drives 70% of cigarette smoke-induced emphysema in the mouse. Am J Respir Crit Care Med 2004, 170:492-498. 10.1164/rccm.200404-511OC, 15184206.
-
(2004)
Am J Respir Crit Care Med
, vol.170
, pp. 492-498
-
-
Churg, A.1
Wang, R.D.2
Tai, H.3
Wang, X.4
Xie, C.5
Wright, J.L.6
-
7
-
-
34247607712
-
The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease
-
10.1164/rccm.200607-995OC, 17290043, COPD Investigators
-
Rennard SI, Fogarty C, Kelsen S, Long W, Ramsdell J, Allison J, Mahler D, Saadeh C, Siler T, Snell P, Korenblat P, Smith W, Kaye M, Mandel M, Andrews C, Prabhu R, Donohue JF, Watt R, Lo KH, Schlenker-Herceg R, Barnathan ES, Murray J, . COPD Investigators The safety and efficacy of infliximab in moderate to severe chronic obstructive pulmonary disease. Am J Respir Crit Care Med 2007, 175:926-934. 10.1164/rccm.200607-995OC, 17290043, COPD Investigators.
-
(2007)
Am J Respir Crit Care Med
, vol.175
, pp. 926-934
-
-
Rennard, S.I.1
Fogarty, C.2
Kelsen, S.3
Long, W.4
Ramsdell, J.5
Allison, J.6
Mahler, D.7
Saadeh, C.8
Siler, T.9
Snell, P.10
Korenblat, P.11
Smith, W.12
Kaye, M.13
Mandel, M.14
Andrews, C.15
Prabhu, R.16
Donohue, J.F.17
Watt, R.18
Lo, K.H.19
Schlenker-Herceg, R.20
Barnathan, E.S.21
Murray, J.22
more..
-
8
-
-
13644267621
-
Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect
-
10.1152/ajplung.00317.2004, 15516486
-
Stevenson CS, Coote K, Webster R, Johnston H, Atherton HC, Nicholls A, Giddings J, Sugar R, Jackson A, Press NJ, Brown Z, Butler K, Danahay H. Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect. Am J Physiol Lung Cell Mol Physiol 2005, 288:L514-L522. 10.1152/ajplung.00317.2004, 15516486.
-
(2005)
Am J Physiol Lung Cell Mol Physiol
, vol.288
-
-
Stevenson, C.S.1
Coote, K.2
Webster, R.3
Johnston, H.4
Atherton, H.C.5
Nicholls, A.6
Giddings, J.7
Sugar, R.8
Jackson, A.9
Press, N.J.10
Brown, Z.11
Butler, K.12
Danahay, H.13
-
9
-
-
33646570904
-
Effect of adenosine A2A receptor activation in murine models of respiratory disorders
-
10.1152/ajplung.00422.2005, 16339780
-
Bonneau O, Wyss D, Ferretti S, Blaydon C, Stevenson CS, Trifilieff A. Effect of adenosine A2A receptor activation in murine models of respiratory disorders. Am J Physiol Lung Cell Mol Physiol 2006, 290:L1036-L1043. 10.1152/ajplung.00422.2005, 16339780.
-
(2006)
Am J Physiol Lung Cell Mol Physiol
, vol.290
-
-
Bonneau, O.1
Wyss, D.2
Ferretti, S.3
Blaydon, C.4
Stevenson, C.S.5
Trifilieff, A.6
-
10
-
-
57349198824
-
Comparison of cigarette smoke-induced acute inflammation in multiple strains of mice and the effect of a matrix metalloproteinase inhibitor on these responses
-
Morris A, Kinnear G, Wan WY, Wyss D, Bahra P, Stevenson CS. Comparison of cigarette smoke-induced acute inflammation in multiple strains of mice and the effect of a matrix metalloproteinase inhibitor on these responses. J Pharmacol Exp Ther 2007, 327:851-862.
-
(2007)
J Pharmacol Exp Ther
, vol.327
, pp. 851-862
-
-
Morris, A.1
Kinnear, G.2
Wan, W.Y.3
Wyss, D.4
Bahra, P.5
Stevenson, C.S.6
-
11
-
-
25444476938
-
Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke
-
10.1164/rccm.200411-1549OC, 15961691
-
Martorana PA, Beume R, Lucattelli M, Wollin L, Lungarella G. Roflumilast fully prevents emphysema in mice chronically exposed to cigarette smoke. Am J Respir Crit Care Med 2005, 172:848-853. 10.1164/rccm.200411-1549OC, 15961691.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 848-853
-
-
Martorana, P.A.1
Beume, R.2
Lucattelli, M.3
Wollin, L.4
Lungarella, G.5
-
12
-
-
33750725415
-
Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice
-
10.1183/09031936.06.00076905, 16510458
-
Leclerc O, Lagente V, Planquois JM, Berthelier C, Artola M, Eichholtz T, Bertrand CP, Schmidlin F. Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice. Eur Respir J 2006, 27:1102-1109. 10.1183/09031936.06.00076905, 16510458.
-
(2006)
Eur Respir J
, vol.27
, pp. 1102-1109
-
-
Leclerc, O.1
Lagente, V.2
Planquois, J.M.3
Berthelier, C.4
Artola, M.5
Eichholtz, T.6
Bertrand, C.P.7
Schmidlin, F.8
-
13
-
-
26944462695
-
Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs
-
10.1164/rccm.200501-041OC, 16002570
-
Lee JH, Lee DS, Kim EK, Choe KH, Oh YM, Shim TS, Kim SE, Lee YS, Lee SD. Simvastatin inhibits cigarette smoking-induced emphysema and pulmonary hypertension in rat lungs. Am J Respir Crit Care Med 2005, 172:987-993. 10.1164/rccm.200501-041OC, 16002570.
-
(2005)
Am J Respir Crit Care Med
, vol.172
, pp. 987-993
-
-
Lee, J.H.1
Lee, D.S.2
Kim, E.K.3
Choe, K.H.4
Oh, Y.M.5
Shim, T.S.6
Kim, S.E.7
Lee, Y.S.8
Lee, S.D.9
-
14
-
-
23144466310
-
Time course of cigarette smoke-induced pulmonary inflammation in mice
-
10.1183/09031936.05.00095204, 16055867
-
Dhulst AI, Vermaelen KY, Brusselle GG, Joos GF, Pauwels RA. Time course of cigarette smoke-induced pulmonary inflammation in mice. Eur Respir J 2005, 26:204-213. 10.1183/09031936.05.00095204, 16055867.
-
(2005)
Eur Respir J
, vol.26
, pp. 204-213
-
-
Dhulst, A.I.1
Vermaelen, K.Y.2
Brusselle, G.G.3
Joos, G.F.4
Pauwels, R.A.5
-
15
-
-
33751216739
-
Murine TLR4 is implicated in cigarette smoke-induced pulmonary inflammation
-
10.1159/000095462, 16940747
-
Maes T, Bracke KR, Vermaelen KY, Demedts IK, Joos GF, Pauwels RA, Brusselle GG. Murine TLR4 is implicated in cigarette smoke-induced pulmonary inflammation. Int Arch Allergy Immunol 2006, 141:354-368. 10.1159/000095462, 16940747.
-
(2006)
Int Arch Allergy Immunol
, vol.141
, pp. 354-368
-
-
Maes, T.1
Bracke, K.R.2
Vermaelen, K.Y.3
Demedts, I.K.4
Joos, G.F.5
Pauwels, R.A.6
Brusselle, G.G.7
-
16
-
-
47249112549
-
The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke
-
LeQuement C, Guenon I, Gillon J-Y, Valenca S, Cayron-Elizondo V, Lagente V, Boichot E. The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke. Brit J Pharm 2008, 154:1206-1215.
-
(2008)
Brit J Pharm
, vol.154
, pp. 1206-1215
-
-
LeQuement, C.1
Guenon, I.2
Gillon, J.-.Y.3
Valenca, S.4
Cayron-Elizondo, V.5
Lagente, V.6
Boichot, E.7
-
17
-
-
0032790739
-
Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema
-
Ofulue AF, Ko M. Effects of depletion of neutrophils or macrophages on development of cigarette smoke-induced emphysema. Am J Physiol 1999, 277:L97-L105.
-
(1999)
Am J Physiol
, vol.277
-
-
Ofulue, A.F.1
Ko, M.2
-
18
-
-
34250197133
-
CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice
-
Maeno T, Houghton AM, Quintero PA, Grumelli S, Owen CA, Shapiro SD. CD8+ T Cells are required for inflammation and destruction in cigarette smoke-induced emphysema in mice. J Immunol 2007, 178:8090-8096.
-
(2007)
J Immunol
, vol.178
, pp. 8090-8096
-
-
Maeno, T.1
Houghton, A.M.2
Quintero, P.A.3
Grumelli, S.4
Owen, C.A.5
Shapiro, S.D.6
-
19
-
-
0033987474
-
Fluvastatin suppresses atherosclerotic progression, mediated through its inhibitory effect on endothelial dysfunction, lipid peroxidation, and macrophage deposition
-
10.1097/00005344-200001000-00018, 10630744
-
Bandoh T, Mitani H, Niihashi M, Kusumi Y, Kimura M, Ishikawa J, Totsuka T, Sakurai I, Hayashi S. Fluvastatin suppresses atherosclerotic progression, mediated through its inhibitory effect on endothelial dysfunction, lipid peroxidation, and macrophage deposition. J Cardiovasc Pharmacol 2000, 35:136-144. 10.1097/00005344-200001000-00018, 10630744.
-
(2000)
J Cardiovasc Pharmacol
, vol.35
, pp. 136-144
-
-
Bandoh, T.1
Mitani, H.2
Niihashi, M.3
Kusumi, Y.4
Kimura, M.5
Ishikawa, J.6
Totsuka, T.7
Sakurai, I.8
Hayashi, S.9
-
20
-
-
79551581154
-
An Acute Model of Cigarette Smoke-Induced Inflammation in Rat that is Partially Steroid-Insensitive
-
Stevenson CS, Coote K, Webster R, Nicholls A, Giddings J, Butler K, Danahay H. An Acute Model of Cigarette Smoke-Induced Inflammation in Rat that is Partially Steroid-Insensitive. Inflamm Res 2003, 52:s85.
-
(2003)
Inflamm Res
, vol.52
-
-
Stevenson, C.S.1
Coote, K.2
Webster, R.3
Nicholls, A.4
Giddings, J.5
Butler, K.6
Danahay, H.7
-
21
-
-
77953646802
-
Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice
-
10.4049/jimmunol.0900963, 20488786
-
Vernooy JH, Bracke KR, Drummen NE, Pauwels NS, Zabeau L, van Suylen RJ, Tavernier J, Joos GF, Wouters EF, Brusselle GG. Leptin modulates innate and adaptive immune cell recruitment after cigarette smoke exposure in mice. J Immunol 2010, 184:7169-7177. 10.4049/jimmunol.0900963, 20488786.
-
(2010)
J Immunol
, vol.184
, pp. 7169-7177
-
-
Vernooy, J.H.1
Bracke, K.R.2
Drummen, N.E.3
Pauwels, N.S.4
Zabeau, L.5
van Suylen, R.J.6
Tavernier, J.7
Joos, G.F.8
Wouters, E.F.9
Brusselle, G.G.10
-
22
-
-
9744220302
-
Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs
-
10.1165/rcmb.2004-0006OC, 15333327
-
Marwick JA, Kirkham PA, Stevenson CS, Danahay H, Giddings J, Butler K, Donaldson K, Macnee W, Rahman I. Cigarette smoke alters chromatin remodeling and induces proinflammatory genes in rat lungs. Am J Respir Cell Mol Biol 2004, 31:633-642. 10.1165/rcmb.2004-0006OC, 15333327.
-
(2004)
Am J Respir Cell Mol Biol
, vol.31
, pp. 633-642
-
-
Marwick, J.A.1
Kirkham, P.A.2
Stevenson, C.S.3
Danahay, H.4
Giddings, J.5
Butler, K.6
Donaldson, K.7
Macnee, W.8
Rahman, I.9
-
23
-
-
0035253604
-
Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity
-
Belvisi MG, Wicks SL, Battram CH, Bottoms SE, Redford JE, Woodman P, Brown TJ, Webber SE, Foster ML. Therapeutic benefit of a dissociated glucocorticoid and the relevance of in vitro separation of transrepression from transactivation activity. J Immunol 2001, 166:1975-1982.
-
(2001)
J Immunol
, vol.166
, pp. 1975-1982
-
-
Belvisi, M.G.1
Wicks, S.L.2
Battram, C.H.3
Bottoms, S.E.4
Redford, J.E.5
Woodman, P.6
Brown, T.J.7
Webber, S.E.8
Foster, M.L.9
-
24
-
-
0034079575
-
Loteprednol etabonate: a soft steroid for the treatment of allergic diseases of the airways
-
Szelenyi I, Hochhaus G, Heer S, Kusters S, Marx D, Poppe H, Engel J. Loteprednol etabonate: a soft steroid for the treatment of allergic diseases of the airways. Drugs Today (Barc) 2000, 36:313-320.
-
(2000)
Drugs Today (Barc)
, vol.36
, pp. 313-320
-
-
Szelenyi, I.1
Hochhaus, G.2
Heer, S.3
Kusters, S.4
Marx, D.5
Poppe, H.6
Engel, J.7
-
25
-
-
33846931592
-
Statin use is associated with reduced mortality in COPD
-
10.1183/09031936.00106406, 17050558
-
Søyseth V, Brekke PH, Smith P, Omland T. Statin use is associated with reduced mortality in COPD. Eur Respir J 2007, 29:279-283. 10.1183/09031936.00106406, 17050558.
-
(2007)
Eur Respir J
, vol.29
, pp. 279-283
-
-
Søyseth, V.1
Brekke, P.H.2
Smith, P.3
Omland, T.4
-
26
-
-
33744994082
-
Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease
-
10.1016/j.jacc.2006.04.039, 16781387
-
Mancini GB, Etminan M, Zhang B, Levesque LE, FitzGerald JM, Brophy JM. Reduction of morbidity and mortality by statins, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers in patients with chronic obstructive pulmonary disease. J Am Coll Cardiol 2006, 47:2554-2560. 10.1016/j.jacc.2006.04.039, 16781387.
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 2554-2560
-
-
Mancini, G.B.1
Etminan, M.2
Zhang, B.3
Levesque, L.E.4
FitzGerald, J.M.5
Brophy, J.M.6
-
27
-
-
0030886472
-
Effects of fluvastatin on leucocyte endothelial cell adhesion in hypercholesterolemic mice
-
Kimura M, Kurose I, Russell J, Granger DN. Effects of fluvastatin on leucocyte endothelial cell adhesion in hypercholesterolemic mice. Arterioscler Thromb Vasc Biol 1997, 17:e1521-e1526.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
-
-
Kimura, M.1
Kurose, I.2
Russell, J.3
Granger, D.N.4
-
28
-
-
0031775709
-
HMG-CoA reductase inhibitors reduce MMP-9 secretion by macrophages
-
Bellosta S, Via D, Canavesi M, Pfister P, Fumagalli R, Paoletti R, Bernini F. HMG-CoA reductase inhibitors reduce MMP-9 secretion by macrophages. Arterioscler Thromb Vasc Biol 1998, 8:1671-1678.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.8
, pp. 1671-1678
-
-
Bellosta, S.1
Via, D.2
Canavesi, M.3
Pfister, P.4
Fumagalli, R.5
Paoletti, R.6
Bernini, F.7
-
29
-
-
0034978984
-
Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation
-
Wong B, Lumma WC, Smith AM, Sisko JT, Wright SD, Cai TQ. Statins suppress THP-1 cell migration and secretion of matrix metalloproteinase 9 by inhibiting geranylgeranylation. J Leukoc Biol 2001, 69:959-962.
-
(2001)
J Leukoc Biol
, vol.69
, pp. 959-962
-
-
Wong, B.1
Lumma, W.C.2
Smith, A.M.3
Sisko, J.T.4
Wright, S.D.5
Cai, T.Q.6
-
30
-
-
36749063803
-
Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD
-
10.1136/thx.2006.075937, 2094292, 17573446
-
Grootendorst DC, Gauw SA, Verhoosel RM, Sterk PJ, Hospers JJ, Bredenbröker D, Bethke TD, Hiemstra PS, Rabe KF. Reduction in sputum neutrophil and eosinophil numbers by the PDE4 inhibitor roflumilast in patients with COPD. Thorax 2007, 62:1081-1087. 10.1136/thx.2006.075937, 2094292, 17573446.
-
(2007)
Thorax
, vol.62
, pp. 1081-1087
-
-
Grootendorst, D.C.1
Gauw, S.A.2
Verhoosel, R.M.3
Sterk, P.J.4
Hospers, J.J.5
Bredenbröker, D.6
Bethke, T.D.7
Hiemstra, P.S.8
Rabe, K.F.9
|