-
2
-
-
0001511433
-
Airway responsiveness
-
Barnes PJ, Grunstein MM, Leff AR, Woolcock AJ, editors. Philadelphia: Lippincott-Raven Publishers
-
Cockcroft DW. Airway responsiveness. In: Barnes PJ, Grunstein MM, Leff AR, Woolcock AJ, editors. Asthma. Philadelphia: Lippincott-Raven Publishers; 1997. p. 1253-1266.
-
(1997)
Asthma
, pp. 1253-1266
-
-
Cockcroft, D.W.1
-
3
-
-
0025324736
-
Mucosal inflammation in asthma
-
Djukanovic R, Roche WR, Wilson JW, Beasley CRW, Twentyman OP, Howarth PH, Holgate ST. Mucosal inflammation in asthma. Am Rev Respir Dis 1990;142:434-457.
-
(1990)
Am Rev Respir Dis
, vol.142
, pp. 434-457
-
-
Djukanovic, R.1
Roche, W.R.2
Wilson, J.W.3
Beasley, C.R.W.4
Twentyman, O.P.5
Howarth, P.H.6
Holgate, S.T.7
-
4
-
-
0026443197
-
T-cells and eosinophils in the pathogenesis of asthma
-
Corrigan CJ, Kay AB. T-cells and eosinophils in the pathogenesis of asthma. Immunol Today 1992;113:501-507.
-
(1992)
Immunol Today
, vol.113
, pp. 501-507
-
-
Corrigan, C.J.1
Kay, A.B.2
-
5
-
-
0036223582
-
CD4(+) T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma
-
Foster PS, Yang M, Herbert C, Kumar RK. CD4(+) T-lymphocytes regulate airway remodeling and hyper-reactivity in a mouse model of chronic asthma. Lab Invest 2002;82:455-462.
-
(2002)
Lab Invest
, vol.82
, pp. 455-462
-
-
Foster, P.S.1
Yang, M.2
Herbert, C.3
Kumar, R.K.4
-
6
-
-
0026719193
-
Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse
-
Renz H, Smith HR, Henson JE, Ray PS, Irvin CG, Gelfand EW. Aerosolized antigen exposure without adjuvant causes increased IgE production and increased airway responsiveness in the mouse. J Allergy Clin Immunol 1992;89:1127-1138.
-
(1992)
J Allergy Clin Immunol
, vol.89
, pp. 1127-1138
-
-
Renz, H.1
Smith, H.R.2
Henson, J.E.3
Ray, P.S.4
Irvin, C.G.5
Gelfand, E.W.6
-
7
-
-
0030068235
-
Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity
-
Corry DB, Folkesson HG, Warnock ML, Erie DJ, Matthay MA, Wiener-Kronish JP, Locksley RM. Interleukin 4, but not interleukin 5 or eosinophils, is required in a murine model of acute airway hyperreactivity. J Exp Med 1996;183:109-117.
-
(1996)
J Exp Med
, vol.183
, pp. 109-117
-
-
Corry, D.B.1
Folkesson, H.G.2
Warnock, M.L.3
Erie, D.J.4
Matthay, M.A.5
Wiener-Kronish, J.P.6
Locksley, R.M.7
-
8
-
-
0030028768
-
Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model
-
Foster PS, Hogan SP, Ramsay AJ, Matthaei KI, Young IG. Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model. J Exp Med 1996;183:195-201.
-
(1996)
J Exp Med
, vol.183
, pp. 195-201
-
-
Foster, P.S.1
Hogan, S.P.2
Ramsay, A.J.3
Matthaei, K.I.4
Young, I.G.5
-
9
-
-
0031156474
-
Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness
-
Hamelmann E, Oshiba A, Schwarze J, Bradley K, Loader J, Larsen GL, Gelfand EW. Allergen-specific IgE and IL-5 are essential for the development of airway hyperresponsiveness. Am J Respir Cell Mol Biol 1997;16:674-682.
-
(1997)
Am J Respir Cell Mol Biol
, vol.16
, pp. 674-682
-
-
Hamelmann, E.1
Oshiba, A.2
Schwarze, J.3
Bradley, K.4
Loader, J.5
Larsen, G.L.6
Gelfand, E.W.7
-
10
-
-
0030953977
-
Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins
-
Hogan SP, Mould A, Kikutani H, Ramsay AJ, Foster PS. Aeroallergen- induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins. J Clin Invest 1997;99:1329-1339.
-
(1997)
J Clin Invest
, vol.99
, pp. 1329-1339
-
-
Hogan, S.P.1
Mould, A.2
Kikutani, H.3
Ramsay, A.J.4
Foster, P.S.5
-
11
-
-
0028260378
-
Attenuation of allergic airway inflammation in IL-4 deficient mice
-
Brusselle GG, Kips JC, Tavernier JH, van der Heyden JG, Cuvelier CA, Pauwels RA, Bluethmann H. Attenuation of allergic airway inflammation in IL-4 deficient mice. Clin Exp Allergy 1994;24:73-80.
-
(1994)
Clin Exp Allergy
, vol.24
, pp. 73-80
-
-
Brusselle, G.G.1
Kips, J.C.2
Tavernier, J.H.3
Van Der Heyden, J.G.4
Cuvelier, C.A.5
Pauwels, R.A.6
Bluethmann, H.7
-
12
-
-
13344277358
-
IL-5-deficient mice have a developmental defect in CD5(+) B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses
-
Kopf M, Brombacher F, Hodgkin PD, Ramsay AJ, Milbourne EA, Dai WJ, Ovington KS, Behm CA, Kohler G, Young IG, et al. IL-5-deficient mice have a developmental defect in CD5(+) B-1 cells and lack eosinophilia but have normal antibody and cytotoxic T cell responses. Immunity 1996;4:15-24.
-
(1996)
Immunity
, vol.4
, pp. 15-24
-
-
Kopf, M.1
Brombacher, F.2
Hodgkin, P.D.3
Ramsay, A.J.4
Milbourne, E.A.5
Dai, W.J.6
Ovington, K.S.7
Behm, C.A.8
Kohler, G.9
Young, I.G.10
-
13
-
-
0031004365
-
Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice
-
Gavett SH, O'Hearn DJ, Karp CL, Patel EA, Schofield BH, Finkelman FD, Wills-Karp M. Interleukin-4 receptor blockade prevents airway responses induced by antigen challenge in mice. Am J Physiol 1997; 272:L253-L261.
-
(1997)
Am J Physiol
, vol.272
-
-
Gavett, S.H.1
O'Hearn, D.J.2
Karp, C.L.3
Patel, E.A.4
Schofield, B.H.5
Finkelman, F.D.6
Wills-Karp, M.7
-
14
-
-
0031830756
-
Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice
-
Corry DB, Grunig G, Hadeiba H, Kurup VP, Warnock ML, Sheppard D, Rennick DM, Locksley RM. Requirements for allergen-induced airway hyperreactivity in T and B cell-deficient mice. Mol Med 1998;4: 344-355.
-
(1998)
Mol Med
, vol.4
, pp. 344-355
-
-
Corry, D.B.1
Grunig, G.2
Hadeiba, H.3
Kurup, V.P.4
Warnock, M.L.5
Sheppard, D.6
Rennick, D.M.7
Locksley, R.M.8
-
15
-
-
0032545213
-
Interleukin-13: Central mediator of allergic asthma
-
Wills-Karp M, Luyimbazi MJ, Xu X, Schofield B, Neben TY, Karp CL, Donaldson DD. Interleukin-13: central mediator of allergic asthma. Science 1998;282:2258-2261.
-
(1998)
Science
, vol.282
, pp. 2258-2261
-
-
Wills-Karp, M.1
Luyimbazi, M.J.2
Xu, X.3
Schofield, B.4
Neben, T.Y.5
Karp, C.L.6
Donaldson, D.D.7
-
16
-
-
0032545433
-
Requirement for IL-13 independently of IL-4 in experimental asthma
-
Grunig G, Warnock M, Wakil AE, Venkayya R, Brombacher F, Rennick DM, Sheppard D, Mohrs M, Donaldson DD, Locksley RM, et al. Requirement for IL-13 independently of IL-4 in experimental asthma. Science 1998;282:2261-2263.
-
(1998)
Science
, vol.282
, pp. 2261-2263
-
-
Grunig, G.1
Warnock, M.2
Wakil, A.E.3
Venkayya, R.4
Brombacher, F.5
Rennick, D.M.6
Sheppard, D.7
Mohrs, M.8
Donaldson, D.D.9
Locksley, R.M.10
-
17
-
-
0033560126
-
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
-
Zhu Z, Homer RJ, Wang Z, Chen Q, Geba GP, Wang J, Zhang Y, Elias JA. Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production. J Clin Invest 1999;103:779-788.
-
(1999)
J Clin Invest
, vol.103
, pp. 779-788
-
-
Zhu, Z.1
Homer, R.J.2
Wang, Z.3
Chen, Q.4
Geba, G.P.5
Wang, J.6
Zhang, Y.7
Elias, J.A.8
-
18
-
-
0034235875
-
Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity
-
Webb DC, McKenzie AN, Koskinen AM, Yang M, Mattes J, Foster PS. Integrated signals between IL-13, IL-4, and IL-5 regulate airways hyperreactivity. J Immunol 2000;165:108-113.
-
(2000)
J Immunol
, vol.165
, pp. 108-113
-
-
Webb, D.C.1
McKenzie, A.N.2
Koskinen, A.M.3
Yang, M.4
Mattes, J.5
Foster, P.S.6
-
19
-
-
0036344597
-
Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma
-
Kuperman DA, Huang X, Koth LL, Chang GH, Dolganov GM, Zhu Z, Elias JA, Sheppard D, Erle DJ. Direct effects of interleukin-13 on epithelial cells cause airway hyperreactivity and mucus overproduction in asthma. Nat Med 2002;8:885-889.
-
(2002)
Nat Med
, vol.8
, pp. 885-889
-
-
Kuperman, D.A.1
Huang, X.2
Koth, L.L.3
Chang, G.H.4
Dolganov, G.M.5
Zhu, Z.6
Elias, J.A.7
Sheppard, D.8
Erle, D.J.9
-
20
-
-
0023831561
-
Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma: Relationship to bronchial hyperreactivity
-
Wardlaw AJ, Dunnette S, Gleich GJ, Collins JV, Kay AB. Eosinophils and mast cells in bronchoalveolar lavage in subjects with mild asthma: relationship to bronchial hyperreactivity. Am Rev Respir Dis 1988;137: 62-69.
-
(1988)
Am Rev Respir Dis
, vol.137
, pp. 62-69
-
-
Wardlaw, A.J.1
Dunnette, S.2
Gleich, G.J.3
Collins, J.V.4
Kay, A.B.5
-
21
-
-
0025667042
-
Allergen-induced increase in airway responsiveness and inflammation in mild asthma
-
Brusasco V, Crimi E, Gianiorio P, Lantero S, Rossi GA. Allergen-induced increase in airway responsiveness and inflammation in mild asthma. J Appl Physiol 1990;69:2209-2214.
-
(1990)
J Appl Physiol
, vol.69
, pp. 2209-2214
-
-
Brusasco, V.1
Crimi, E.2
Gianiorio, P.3
Lantero, S.4
Rossi, G.A.5
-
22
-
-
0026590451
-
Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma
-
Djukanovic R, Wilson JW, Britten KM, Wilson SJ, Walls AF, Roche WR, Howarth PH, Holgate ST. Effect of an inhaled corticosteroid on airway inflammation and symptoms in asthma. Am Rev Respir Dis 1992;145:669-674.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 669-674
-
-
Djukanovic, R.1
Wilson, J.W.2
Britten, K.M.3
Wilson, S.J.4
Walls, A.F.5
Roche, W.R.6
Howarth, P.H.7
Holgate, S.T.8
-
23
-
-
0026606394
-
Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma: A quantitative light and electron microscopic study
-
Jeffery PK, Godfrey RW, Adelroth E, Nelson F, Rogers A, Johansson SA. Effects of treatment on airway inflammation and thickening of basement membrane reticular collagen in asthma: a quantitative light and electron microscopic study. Am Rev Respir Dis 1992;145:890-899.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 890-899
-
-
Jeffery, P.K.1
Godfrey, R.W.2
Adelroth, E.3
Nelson, F.4
Rogers, A.5
Johansson, S.A.6
-
24
-
-
0032938331
-
Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment: The AMPUL Study Group
-
Sont JK, Willems LN, Bel EH, van Krieken JH, Vandenbroucke JP, Sterk PJ. Clinical control and histopathologic outcome of asthma when using airway hyperresponsiveness as an additional guide to long-term treatment: The AMPUL Study Group. Am J Respir Crit Care Med 1999; 159:1043-1051.
-
(1999)
Am J Respir Crit Care Med
, vol.159
, pp. 1043-1051
-
-
Sont, J.K.1
Willems, L.N.2
Bel, E.H.3
Van Krieken, J.H.4
Vandenbroucke, J.P.5
Sterk, P.J.6
-
25
-
-
0033935461
-
Comparison of once- with twice-daily dosing of fluticasone propionate in mild and moderate asthma
-
Boulet LP, Cowie RL, Negro RD, Brett W, Gold M, Marques A, Thorburn WS, Stepner NM, Robson R. Comparison of once-with twice-daily dosing of fluticasone propionate in mild and moderate asthma. Can Respir J 2000;7:239-247.
-
(2000)
Can Respir J
, vol.7
, pp. 239-247
-
-
Boulet, L.P.1
Cowie, R.L.2
Negro, R.D.3
Brett, W.4
Gold, M.5
Marques, A.6
Thorburn, W.S.7
Stepner, N.M.8
Robson, R.9
-
26
-
-
0026876092
-
A model of airway narrowing in asthma and in chronic obstructive pulmonary disease
-
Wiggs BR, Bosken C, Pare PD, James A, Hogg JC. A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1992;145:1251-1258.
-
(1992)
Am Rev Respir Dis
, vol.145
, pp. 1251-1258
-
-
Wiggs, B.R.1
Bosken, C.2
Pare, P.D.3
James, A.4
Hogg, J.C.5
-
27
-
-
0027318687
-
Functional significance of increased airway smooth muscle in asthma and COPD
-
Lambert RK, Wiggs BR, Kuwano K, Hogg JC, Pare PD. Functional significance of increased airway smooth muscle in asthma and COPD. J Appl Physiol 1993;74:2771-2781.
-
(1993)
J Appl Physiol
, vol.74
, pp. 2771-2781
-
-
Lambert, R.K.1
Wiggs, B.R.2
Kuwano, K.3
Hogg, J.C.4
Pare, P.D.5
-
28
-
-
0027365905
-
Small airways dimensions in asthma and in chronic obstructive pulmonary disease
-
Kuwano K, Bosken CH, Pare PD, Bai TR, Wiggs BR, Hogg JC. Small airways dimensions in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1993;148:1220-1225.
-
(1993)
Am Rev Respir Dis
, vol.148
, pp. 1220-1225
-
-
Kuwano, K.1
Bosken, C.H.2
Pare, P.D.3
Bai, T.R.4
Wiggs, B.R.5
Hogg, J.C.6
-
29
-
-
0031937746
-
Airway inflammation and structural changes in airway hyper- responsiveness and asthma: An overview
-
Boulet LP, Chakir J, Dube J, Laprise C, Boutet M, Laviolette M. Airway inflammation and structural changes in airway hyper-responsiveness and asthma: an overview. Can Respir J 1998;5:16-21.
-
(1998)
Can Respir J
, vol.5
, pp. 16-21
-
-
Boulet, L.P.1
Chakir, J.2
Dube, J.3
Laprise, C.4
Boutet, M.5
Laviolette, M.6
-
30
-
-
0032826640
-
Asymptomatic airway hyperresponsiveness: Relationships with airway inflammation and remodelling
-
Laprise C, Laviolette M, Boutet M, Boulet LP. Asymptomatic airway hyperresponsiveness: relationships with airway inflammation and remodelling. Eur Respir J 1999;14:63-73.
-
(1999)
Eur Respir J
, vol.14
, pp. 63-73
-
-
Laprise, C.1
Laviolette, M.2
Boutet, M.3
Boulet, L.P.4
-
31
-
-
0033777542
-
Airway hyperresponsiveness, inflammation, and subepithelial collagen deposition in recently diagnosed versus long-standing mild asthma: Influence of inhaled corticosteroids
-
Boulet LP, Turcotte H, Laviolette M, Naud F, Bernier MC, Martel S, Chakir J. Airway hyperresponsiveness, inflammation, and subepithelial collagen deposition in recently diagnosed versus long-standing mild asthma: influence of inhaled corticosteroids. Am J Respir Crit Care Med 2000;162:1308-1313.
-
(2000)
Am J Respir Crit Care Med
, vol.162
, pp. 1308-1313
-
-
Boulet, L.P.1
Turcotte, H.2
Laviolette, M.3
Naud, F.4
Bernier, M.C.5
Martel, S.6
Chakir, J.7
-
32
-
-
0034132033
-
Chronic airway hyperreactivity, goblet cell hyperplasia, and peribronchial fibrosis during allergic airway disease induced by Aspergillus fumigatus
-
Hogaboam CM, Blease K, Mehrad B, Steinhauser ML, Standiford TJ, Kunkel SL, Lukacs NW. Chronic airway hyperreactivity, goblet cell hyperplasia, and peribronchial fibrosis during allergic airway disease induced by Aspergillus fumigatus. Am J Pathol 2000;156:723-732.
-
(2000)
Am J Pathol
, vol.156
, pp. 723-732
-
-
Hogaboam, C.M.1
Blease, K.2
Mehrad, B.3
Steinhauser, M.L.4
Standiford, T.J.5
Kunkel, S.L.6
Lukacs, N.W.7
-
33
-
-
0024828192
-
Bronchial biopsies in asthma: An ultrastructural, quantitative study and correlation with hyperreactivity
-
Jeffery PK, Wardlaw AJ, Nelson FC, Collins JV, Kay AB. Bronchial biopsies in asthma: an ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 1989;140:1745-1753.
-
(1989)
Am Rev Respir Dis
, vol.140
, pp. 1745-1753
-
-
Jeffery, P.K.1
Wardlaw, A.J.2
Nelson, F.C.3
Collins, J.V.4
Kay, A.B.5
-
35
-
-
0027404742
-
The structure of large and small airways in nonfatal and fatal asthma
-
Carroll N, Elliot J, Morton A, James AL. The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis 1993;147: 405-410.
-
(1993)
Am Rev Respir Dis
, vol.147
, pp. 405-410
-
-
Carroll, N.1
Elliot, J.2
Morton, A.3
James, A.L.4
-
36
-
-
0028999266
-
Mechanisms of airway narrowing and hyperresponsiveness in viral respiratory tract infections
-
Hegele RG, Hayashi S, Hogg JC, Pare PD. Mechanisms of airway narrowing and hyperresponsiveness in viral respiratory tract infections. Am J Respir Crit Care Med 1995;151:1659-1664.
-
(1995)
Am J Respir Crit Care Med
, vol.151
, pp. 1659-1664
-
-
Hegele, R.G.1
Hayashi, S.2
Hogg, J.C.3
Pare, P.D.4
-
38
-
-
0037115314
-
The relationship of reticular basement membrane thickness to airway wall remodeling in asthma
-
James AL, Maxwell PS, Pearce-Pinto G, Elliot JG, Carroll NG. The relationship of reticular basement membrane thickness to airway wall remodeling in asthma. Am J Respir Crit Care Med 2002;166:1590-1595.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 1590-1595
-
-
James, A.L.1
Maxwell, P.S.2
Pearce-Pinto, G.3
Elliot, J.G.4
Carroll, N.G.5
-
42
-
-
0036846991
-
Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation
-
Leigh R, Ellis R, Wattie J, Southam DS, De Hoogh M, Gauldie J, O'Byrne PM, Inman MD. Dysfunction and remodeling of the mouse airway persist after resolution of acute allergen-induced airway inflammation. Am J Respir Cell Mol Biol 2002;27:526-535.
-
(2002)
Am J Respir Cell Mol Biol
, vol.27
, pp. 526-535
-
-
Leigh, R.1
Ellis, R.2
Wattie, J.3
Southam, D.S.4
De Hoogh, M.5
Gauldie, J.6
O'Byrne, P.M.7
Inman, M.D.8
-
43
-
-
0031781163
-
An improved murine model of asthma: Selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen
-
Temelkovski J, Hogan SP, Shepherd DP, Foster PS, Kumar RK. An improved murine model of asthma: selective airway inflammation, epithelial lesions and increased methacholine responsiveness following chronic exposure to aerosolised allergen. Thorax 1998;53:849-856.
-
(1998)
Thorax
, vol.53
, pp. 849-856
-
-
Temelkovski, J.1
Hogan, S.P.2
Shepherd, D.P.3
Foster, P.S.4
Kumar, R.K.5
-
44
-
-
0034529934
-
Time course of inflammatory and remodeling events in a murine model of asthma: Effect of steroid treatment
-
Trifilieff A, El Hashim A, Bertrand C. Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment. Am J Physiol Lung Cell Mol Physiol 2000;279:L1120-L1128.
-
(2000)
Am J Physiol Lung Cell Mol Physiol
, vol.279
-
-
Trifilieff, A.1
El Hashim, A.2
Bertrand, C.3
-
45
-
-
0034108186
-
Prolonged allergen exposure induces structural airway changes in sensitized rats
-
Palmans E, Kips JC, Pauwels RA. Prolonged allergen exposure induces structural airway changes in sensitized rats. Am J Respir Crit Care Med 2000;161:627-635.
-
(2000)
Am J Respir Crit Care Med
, vol.161
, pp. 627-635
-
-
Palmans, E.1
Kips, J.C.2
Pauwels, R.A.3
-
46
-
-
0035661260
-
The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma
-
Tanaka H, Masuda T, Tokuoka S, Komai M, Nagao K, Takahashi Y, Nagai H. The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma. Inflamm Res 2001; 50:616-624.
-
(2001)
Inflamm Res
, vol.50
, pp. 616-624
-
-
Tanaka, H.1
Masuda, T.2
Tokuoka, S.3
Komai, M.4
Nagao, K.5
Takahashi, Y.6
Nagai, H.7
-
47
-
-
25344453489
-
IL-4 and IL-13, but not IL-5 are critical for the development of sustained airway hyperreactivity and airway remodeling following chronic allergen challenge in mice
-
Leigh R, Ellis R, Wattie J, Hirota J, O'Byrne PM, Inman MD. IL-4 and IL-13, but not IL-5 are critical for the development of sustained airway hyperreactivity and airway remodeling following chronic allergen challenge in mice [abstract]. Am J Respir Crit Care Med 2003;167:A494.
-
(2003)
Am J Respir Crit Care Med
, vol.167
-
-
Leigh, R.1
Ellis, R.2
Wattie, J.3
Hirota, J.4
O'Byrne, P.M.5
Inman, M.D.6
-
48
-
-
0032167664
-
Impaired development of Th2 cells in IL-13-deficient mice
-
McKenzie GJ, Emson CL, Bell SE, Anderson S, Fallon P, Zurawski G, Murray R, Grencis R, McKenzie ANJ. Impaired development of Th2 cells in IL-13-deficient mice. Immunity 1998;9:423-432.
-
(1998)
Immunity
, vol.9
, pp. 423-432
-
-
McKenzie, G.J.1
Emson, C.L.2
Bell, S.E.3
Anderson, S.4
Fallon, P.5
Zurawski, G.6
Murray, R.7
Grencis, R.8
Anj, M.9
-
49
-
-
0033208703
-
Allergen-induced increase in airway responsiveness, airway eosinophilia, and bone-marrow eosinophil progenitors in mice
-
Inman MD, Ellis R, Wattie J, Denburg JA, O'Byrne PM. Allergen-induced increase in airway responsiveness, airway eosinophilia, and bone-marrow eosinophil progenitors in mice. Am J Respir Cell Mol Biol 1999;21:473-479.
-
(1999)
Am J Respir Cell Mol Biol
, vol.21
, pp. 473-479
-
-
Inman, M.D.1
Ellis, R.2
Wattie, J.3
Denburg, J.A.4
O'Byrne, P.M.5
-
50
-
-
0033888924
-
A new ventilator for monitoring lung mechanics in small animals
-
Volgyesi GA, Tremblay LN, Webster P, Zamel N, Slutsky AS. A new ventilator for monitoring lung mechanics in small animals. J Appl Physiol 2000;89:413-421.
-
(2000)
J Appl Physiol
, vol.89
, pp. 413-421
-
-
Volgyesi, G.A.1
Tremblay, L.N.2
Webster, P.3
Zamel, N.4
Slutsky, A.S.5
-
51
-
-
0141478647
-
Morphometric analysis of mouse airways following chronic allergen challenge
-
Ellis R, Leigh R, Southam DS, O'Byrne PM, Inman MD. Morphometric analysis of mouse airways following chronic allergen challenge. Lab Invest 2003;83:1285-1291.
-
(2003)
Lab Invest
, vol.83
, pp. 1285-1291
-
-
Ellis, R.1
Leigh, R.2
Southam, D.S.3
O'Byrne, P.M.4
Inman, M.D.5
-
52
-
-
0034079382
-
Dissociation of inflammatory and epithelial responses in a murine model of chronic asthma
-
Foster PS, Ming Y, Matthei KI, Young IG, Temelkovski J, Kumar RK. Dissociation of inflammatory and epithelial responses in a murine model of chronic asthma. Lab Invest 2000;80:655-662.
-
(2000)
Lab Invest
, vol.80
, pp. 655-662
-
-
Foster, P.S.1
Ming, Y.2
Matthei, K.I.3
Young, I.G.4
Temelkovski, J.5
Kumar, R.K.6
-
53
-
-
0035987319
-
Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma
-
Kumar RK, Herbert C, Yang M, Koskinen AM, McKenzie AN, Foster PS. Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma. Clin Exp Allergy 2002;32:1104-1111.
-
(2002)
Clin Exp Allergy
, vol.32
, pp. 1104-1111
-
-
Kumar, R.K.1
Herbert, C.2
Yang, M.3
Koskinen, A.M.4
McKenzie, A.N.5
Foster, P.S.6
-
54
-
-
0037087365
-
IL-13-induced chemokine responses in the lung: Role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling
-
Zhu Z, Ma B, Zheng T, Homer RJ, Lee CG, Charo IF, Noble P, Elias JA. IL-13-induced chemokine responses in the lung: role of CCR2 in the pathogenesis of IL-13-induced inflammation and remodeling. J Immunol 2002;168:2953-2962.
-
(2002)
J Immunol
, vol.168
, pp. 2953-2962
-
-
Zhu, Z.1
Ma, B.2
Zheng, T.3
Homer, R.J.4
Lee, C.G.5
Charo, I.F.6
Noble, P.7
Elias, J.A.8
-
55
-
-
0034755167
-
Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin
-
Yang M, Hogan SP, Henry PJ, Matthaei KI, McKenzie AN, Young IG, Rothenberg ME, Foster PS. Interleukin-13 mediates airways hyperreactivity through the IL-4 receptor-alpha chain and STAT-6 independently of IL-5 and eotaxin. Am J Respir Cell Mol Biol 2001;25:522-530.
-
(2001)
Am J Respir Cell Mol Biol
, vol.25
, pp. 522-530
-
-
Yang, M.1
Hogan, S.P.2
Henry, P.J.3
Matthaei, K.I.4
McKenzie, A.N.5
Young, I.G.6
Rothenberg, M.E.7
Foster, P.S.8
-
56
-
-
0036644568
-
Con: Mice are not a good model of human airway disease
-
Persson CGA. Con: mice are not a good model of human airway disease. Am J Respir Crit Care Med 2002;166:6-88.
-
(2002)
Am J Respir Crit Care Med
, vol.166
, pp. 6-88
-
-
Persson, C.G.A.1
-
57
-
-
31844443695
-
The environment and disease: Association or causation?
-
Bradford-Hill AB. The environment and disease: association or causation? Proc R Soc Med 1965;58:295-300.
-
(1965)
Proc R Soc Med
, vol.58
, pp. 295-300
-
-
Bradford-Hill, A.B.1
|