Comparison of cigarette smoke-induced acute inflammation in multiple strains of mice and the effect of a matrix metalloproteinase inhibitor on these responses

Journal of Pharmacology and Experimental Therapeutics

Volumn 327, Issue 3, 2008, Pages 851-862

  Morris, Abigail ^a   Kinnear, Gillian ^a   Wan, Wing Yan Heidi ^a   Wyss, Daniel ^a   Bahra, Parmjit ^a   Stevenson, Christopher S ^a,b  

^a NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

^b NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CIGARETTE SMOKE; DRUG VEHICLE; MACROPHAGE ELASTASE; MATRIX METALLOPROTEINASE INHIBITOR; N4 (2,2 DIMETHYL 1 METHYLCARBAMOYLPROPYL) N1 HYDROXY 2 HYDROXYMETHYL 3 (4 METHOXYPHENYL)SUCCINIMIDE; PKF 242484; UNCLASSIFIED DRUG;

129 MOUSE; A J MOUSE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BAGG ALBINO MOUSE; C57BL 6 MOUSE; CHRONIC OBSTRUCTIVE LUNG DISEASE; CIGARETTE SMOKING; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG ADMINISTRATION ROUTE; ENZYME ACTIVITY; ENZYME SPECIFICITY; FEMALE; GENE EXPRESSION REGULATION; INFLAMMATION; KERATINOCYTE; MACROPHAGE ACTIVATION; MOUSE; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE;

ANIMALS; CHEMOTAXIS; INFLAMMATION; KERATINOCYTES; MATRIX METALLOPROTEINASE 12; MATRIX METALLOPROTEINASES; MICE; NEUTROPHILS; PROTEASE INHIBITORS; SMOKE; SPECIES SPECIFICITY; UP-REGULATION;

EID: 57349198824     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.108.140848     Document Type: Article

References (25)

1. Abbruzzese TA, Guzman RJ, Martin RL, Yee C, Karins CK, and Dalman RL (1998) Matrix metalloproteinase inhibition limits arterial enlargement in a rodent arteriovenous fistula model. Surgery 124:328-335.
2. Belvisi MG and Bottomley KM (2003) The role of matrix metalloproteinases (MMPs) in the pathophysiology of chronic obstructive pulmonary disease (COPD): a therapeutic role for inhibitors of MMPs? Inflamm Res 52:95-100.
3. Cavarra E, Bartalesi B, Lucattelli M, Fineschi S, Lunghi B, Gambelli F, Ortiz LA, Martorana PA, and Lungarella G (2001) Effects of cigarette smoke in mice with different levels of α1-proteinase inhibitor and sensitivity to oxidants. Am J Respir Crit Care Med 164:886-890.
4. Churg A, Dai J, Zay K, Karsan A, Hendricks R, Yee C, Martin R, MacKenzie R, Xie C, Zhang L, et al. (2001) Alpha-1-antitrypsin and a broad spectrum metalloprotease inhibitor, RS113456, have similar acute anti-inflammatory effects. Lab Invest 81:1119-1131.
5. Churg A, Wang RD, Tai H, Wang X, Xie C, Dai J, Shapiro SD, and Wright JL (2003) Macrophage metalloelastase mediates acute cigarette smoke-induced inflammation via tumor necrosis factor-alpha release. Am J Respir Crit Care Med 167:1083-1089.
6. Churg A, Zay K, Shay S, Xie C, Shapiro SD, Hendricks R, and Wright JL (2002) Acute cigarette smoke-induced connective tissue breakdown requires both neutrophils and macrophage metalloelastase in mice. Am J Respir Cell Mol Biol 27:368-374.
7. Corteling R, Wyss D, and Trifilieff A (2002) In vivo models of lung neutrophil activation: comparison of mice and hamsters. BMC Pharmacol 2:1.
8. Grumelli S, Corry DB, Song LZ, Song L, Green L, Huh J, Hacken J, Espada R, Bag R, Lewis DE, et al. (2004) An immune basis for lung parenchymal destruction in chronic obstructive pulmonary disease and emphysema. PLoS Med 1:e8.
9. Guerassimov A, Hoshino Y, Takubo Y, Turcotte A, Yamamoto M, Ghezzo H, Triantafillopoulos A, Whittaker K, Hoidal JR, and Cosio MG (2004) The development of emphysema in cigarette smoke-exposed mice is strain dependent. Am J Respir Crit Care Med 170:974-980.
10. Hautamaki RD, Kobayashi DK, Senior RM, and Shapiro SD (1997) Requirement for macrophage elastase for cigarette smoke-induced emphysema in mice. Science 277:2002-2004.
11. Houghton AM, Quintero PA, Perkins DL, Kobayashi DK, Kelley DG, Marconcini LA, Mecham RP, Senior RM, and Shapiro SD (2006) Elastin fragments drive disease progression in a murine model of emphysema. J Clin Invest 116:753-759.
12. Leclerc O, Lagente V, Planquois JM, Berthelier C, Artola M, Eichholtz T, Bertrand CP, and Schmidlin F (2006) Involvement of MMP-12 and phosphodiesterase type 4 in cigarette Smoke-induced inflammation in mice. Eur Respir J 27:1102-1109.
13. Le Quément C, Guénon I, Gillon JY, Valença S, Cayron-Elizondo V, Lagente V, and Boichot E (2008) The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke. Br J Pharmacol 154:1206-1215.
14. MacKay AR, Sedgwick AD, Dunn CJ, Fleming WE, and Willoughby DA (1985) The transition from acute to chronic inflammation. Br J Dermatol 113:34-48.
15. Pauwels RA, Buist AS, Ma P, Jenkins CR, and Hurd SS (2001) Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: National Heart, Lung, and Blood Institute and World Health Organization Global Initiative for Chronic Obstructive Lung Disease (GOLD): executive summary. Respir Care 46:798-825.
16. Pemberton PA, Cantwell JS, Kim KM, Sundin DJ, Kobayashi D, Fink JB, Shapiro SD, and Barr PJ (2005) An inhaled matrix metalloprotease inhibitor prevents cigarette smoke-induced emphysema in the mouse. COPD 2:303-310.
17. Seagrave J, Barr EB, March TH, and Nikula KJ (2004) Effects of cigarette smoke exposure and cessation on inflammatory cells and matrix metalloproteinase activity in mice. Exp Lung Res 30:1-15.
18. Segura-Valdez L, Pardo A, Gaxiola M, Uhal BD, Becerril C, and Selman M (2000) Upregulation of gelatinases A and B, collagenases 1 and 2, and increased parenchymal cell death in COPD. Chest 117:684-694.
19. Stevenson CS, Coote K, Webster R, Johnston H, Atherton HC, Nicholls A, Giddings J, Sugar R, Jackson A, Press NJ, et al. (2005) Characterization of cigarette smoke-induced inflammatory and mucus hypersecretory changes in rat lung and the role of CXCR2 ligands in mediating this effect. Am J Physiol Lung Cell Mol Physiol 288:L514-L522.
20. Thatcher TH, McHugh NA, Egan RW, Chapman RW, Hey JA, Turner CK, Redonnet MR, Seweryniak KE, Sime PJ, and Phipps RP (2005) Role of CXCR2 in cigarette smoke-induced lung inflammation. Am J Physiol Lung Cell Mol Physiol 289:L322-L328.
21. Trifilieff A, El-Hashim A, and Bertrand C (2000) Time course of inflammatory and remodeling events in a murine model of asthma: effect of steroid treatment. Am J Physiol Lung Cell Mol Physiol 279:L1120-L1128.
22. Trifilieff A, Walker C, Keller T, Kottirsch G, and Neumann U (2002) Pharmacological profile of PKF242-484 and PKF241-466, novel dual inhibitors of TNF-alpha converting enzyme and matrix metalloproteinases, in models of airway inflammation. Br J Pharmacol 135:1655-1664.
23. Vlahos R, Bozinovski S, Jones JE, Powell J, Gras J, Lilja A, Hansen MJ, Gualano RC, Irving L, and Anderson GP (2006) Differential protease, innate immunity, and NF-kappaB induction profiles during lung inflammation induced by subchronic cigarette smoke exposure in mice. Am J Physiol Lung Cell Mol Physiol 290:L931-L945.
24. Weathington NM, van Houwelingen AH, Noerager BD, Jackson PL, Kraneveld AD, Galin FS, Folkerts G, Nijkamp FP, and Blalock JE (2006) A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation. Nat Med 12:317-323.
25. Yao H, Edirisinghe I, Rajendrasozhan S, Yang SR, Caito S, Adenuga D, and Rahman I (2008) Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice. Am J Physiol Lung Cell Mol Physiol 294:L1174-L1186.