Gender-dependent pharmacokinetics of lignans in rats after single and multiple oral administration of Schisandra chinensis extract

Journal of Ethnopharmacology

Volumn 147, Issue 1, 2013, Pages 224-231

  Xu, Haiyan ^a   Gan, Jingjing ^a   Liu, Xiaohong ^a   Wu, Ruiyang ^a   Jin, Yi ^a   Li, Mi ^b   Yuan, Bo ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

Author keywords

Lignan; Pharmacokinetics; Schisandra chinensis; UPLC MS MS

Indexed keywords

DEOXYSCHISANDRIN; GOMISIN A; LIGNAN DERIVATIVE; SCHISANDRA CHINENSIS EXTRACT; SCHISANTHERIN A; SCHIZANDRIN B; SCHIZANDRIN C; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG STRUCTURE; FEMALE; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; SCHISANDRA CHINENSIS; SEX DIFFERENCE; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHROMATOGRAPHY, LIQUID; DRUG ADMINISTRATION SCHEDULE; DRUGS, CHINESE HERBAL; FEMALE; HALF-LIFE; LIGNANS; MALE; MEDICINE, CHINESE TRADITIONAL; METABOLIC CLEARANCE RATE; PHYTOTHERAPY; PLANTS, MEDICINAL; RATS; RATS, SPRAGUE-DAWLEY; SCHISANDRA; SEX FACTORS; TANDEM MASS SPECTROMETRY;

RATTUS; SCHISANDRA; SCHISANDRA CHINENSIS;

EID: 84876124499     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2013.03.008     Document Type: Article

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