Simultaneous determination of catechin, epicatechin and epicatechin gallate in rat plasma by LC-ESI-MS/MS for pharmacokinetic studies after oral administration of Cynomorium songaricum extract

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 880, Issue 1, 2012, Pages 168-171

  Zhang, Qiu Hong ^a   Wang, Wen Biao ^b   Li, Jin ^a   Chang, Yan Xu ^a   Wang, Yue Fei ^a   Zhang, Jishu ^b   Zhang, Bo Li ^a   Gao, Xiu Mei ^a  

^a TIANJIN UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

^b Elion Resources Group Company   (China)

Author keywords

Catechin; Cynomorium songaricum Rupr; Epicatechin; Epicatechin gallate; LC MS MS

Indexed keywords

ANALYTES; CATECHIN; CYNOMORIUM SONGARICUM RUPR; EPICATECHIN; GALLATE; INTERNAL STANDARDS; LC-ESI-MS/MS; LC-MS/MS; LOWER LIMITS OF QUANTITATIONS; MOBILE PHASE; ORAL ADMINISTRATION; PHARMACOKINETIC STUDIES; RAT PLASMA; SCOPOLETIN; SIMULTANEOUS DETERMINATIONS;

ACETONITRILE; BODY FLUIDS; FORMIC ACID; PHARMACOKINETICS; RATS;

PHENOLS;

ACETONITRILE; CATECHIN; CYNOMORIUM SONGARICUM EXTRACT; EPICATECHIN; EPICATECHIN GALLATE; FORMIC ACID; PLANT EXTRACT; UNCLASSIFIED DRUG;

ACCURACY; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CYNOMORIUM SONGARICUM; DRUG BLOOD LEVEL; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MAXIMUM PLASMA CONCENTRATION; MEDICINAL PLANT; NONHUMAN; PRIORITY JOURNAL; PROCESS OPTIMIZATION; QUALITY CONTROL; RAT;

ADMINISTRATION, ORAL; ANIMALS; CATECHIN; CHROMATOGRAPHY, LIQUID; CYNOMORIUM; DRUG STABILITY; DRUGS, CHINESE HERBAL; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY;

CYNOMORIUM SONGARICUM; RATTUS;

EID: 84855194842     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2011.11.021     Document Type: Article

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