Highly sensitive determination of Schisandrin and Schisandrin B in plasma of rats after administration of Wurenchun (Fructus Schisandrae Chinensis Extracts) preparations by LC-ESI-MS/MS

Biomedical Chromatography

Volumn 24, Issue 6, 2010, Pages 675-681

  Tang, Jingling ^a   Shao, Bing ^a   Liu, Yan ^a   Liu, Hongmei ^a   Ji, Hongyu ^a   Zhu, Daling ^a   Wu, Linhua ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

LC ESI MS MS; Pharmacokinetics; Schisandrin; Schisandrin B; Wurenchun

Indexed keywords

ELECTROSPRAY IONIZATION; EXTRACTION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PHARMACOKINETICS;

EXTRACT PREPARATIONS; FRUCTUS SCHISANDRAE; LC MS/MS(ESI); LC-ESI-MS/MS; LC/ESI-MS/MS; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; SCHISANDRIN; SCHISANDRIN B; WURENCHUN;

RATS;

ACETONITRILE; ETHER DERIVATIVE; FORMIC ACID; GANTAIXIN; NIMODIPINE; SCHISANDRA CHINENSIS EXTRACT; SCHISANDRIN; SCHIZANDRIN B; TERT BUTYL ETHER; UNCLASSIFIED DRUG; WATER;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG ELIMINATION; DRUG HALF LIFE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; LIQUID CHROMATOGRAPHY; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; RAT; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; SINGLE DRUG DOSE; TANDEM MASS SPECTROMETRY; TIME TO MAXIMUM PLASMA CONCENTRATION; VALIDATION PROCESS;

RATTUS;

EID: 77952752654     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1344     Document Type: Article

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