Inhibition of cytochrome P450 3A4 activity by schisandrol A and gomisin A isolated from Fructus Schisandrae chinensis

Phytomedicine

Volumn 17, Issue 8-9, 2010, Pages 702-705

  Wan, C K ^a   Tse, A K ^b   Yu, Z L ^b   Zhu, G Y ^b   Wang, H ^b   Fong, D W F ^b  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b HONG KONG BAPTIST UNIVERSITY   (Hong Kong)

Author keywords

Cytochrome P450 3A4; Glutathione; Gomisin A; Multidrug resistance; Schisandra chinensis; Schisandrol A

Indexed keywords

CYTOCHROME P450 3A4; GLUTATHIONE; GLYCOPROTEIN P; GOMISIN A; PLANT MEDICINAL PRODUCT; SCHISANDROL A; UNCLASSIFIED DRUG;

ARTICLE; CELL LEVEL; CONTROLLED STUDY; ENZYME INHIBITION; FRUIT; HUMAN; HUMAN CELL; IC 50; MEDICINAL PLANT; PRIORITY JOURNAL; SCHISANDRAE CHINENSIS;

CYCLOOCTANES; CYTOCHROME P-450 CYP3A; DIOXOLES; DRUG RESISTANCE, MULTIPLE; FRUIT; GLUTATHIONE; HEP G2 CELLS; HERB-DRUG INTERACTIONS; HUMANS; INHIBITORY CONCENTRATION 50; LIGNANS; P-GLYCOPROTEIN; PLANT EXTRACTS; SCHISANDRA;

SCHISANDRA CHINENSIS;

EID: 77952290102     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.phymed.2009.12.005     Document Type: Article

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