-
1
-
-
78649650474
-
Carney complex and other conditions associated with micronodular adrenal hyperplasias
-
Almeida M.Q., Stratakis C.A. Carney complex and other conditions associated with micronodular adrenal hyperplasias. Best Pract. Res. Clin. Endocrinol. Metab. 2010, 24:907-914.
-
(2010)
Best Pract. Res. Clin. Endocrinol. Metab.
, vol.24
, pp. 907-914
-
-
Almeida, M.Q.1
Stratakis, C.A.2
-
2
-
-
77952310811
-
Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically-induced skin papillomas by dysregulation of the cell cycle and Wnt signaling
-
Almeida M.Q., Muchow M., Boikos S., Bauer A.J., Griffin K.J., Tsang K.M., Cheadle C., Watkins T., Wen F., Starost M.F., Bossis I., Nesterova N., Stratakis C.A. Mouse Prkar1a haploinsufficiency leads to an increase in tumors in the Trp53+/- or Rb1+/- backgrounds and chemically-induced skin papillomas by dysregulation of the cell cycle and Wnt signaling. Hum. Mol. Genet. 2010, 31:369-379.
-
(2010)
Hum. Mol. Genet.
, vol.31
, pp. 369-379
-
-
Almeida, M.Q.1
Muchow, M.2
Boikos, S.3
Bauer, A.J.4
Griffin, K.J.5
Tsang, K.M.6
Cheadle, C.7
Watkins, T.8
Wen, F.9
Starost, M.F.10
Bossis, I.11
Nesterova, N.12
Stratakis, C.A.13
-
3
-
-
79956313489
-
Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors
-
Almeida M.Q., Tsang K.M., Cheadle C., Watkins T., Grivel J.C., Nesterova M., Goldbach-Mansky R., Stratakis C.A. Protein kinase A regulates caspase-1 via Ets-1 in bone stromal cell-derived lesions: a link between cyclic AMP and pro-inflammatory pathways in osteoblast progenitors. Hum. Mol. Genet. 2011, 20:165-175.
-
(2011)
Hum. Mol. Genet.
, vol.20
, pp. 165-175
-
-
Almeida, M.Q.1
Tsang, K.M.2
Cheadle, C.3
Watkins, T.4
Grivel, J.C.5
Nesterova, M.6
Goldbach-Mansky, R.7
Stratakis, C.A.8
-
4
-
-
79953896631
-
Integrated genomic analysis of nodular tissue in macronodular adrenocortical hyperplasia: progression of tumorigenesis in a disorder associated with multiple benign lesions
-
Almeida M.Q., Harran M., Bimpaki E.I., Hsiao H.-P., Horvath A., Cheadle C., Watkins T., Nesterova M., Stratakis C.A. Integrated genomic analysis of nodular tissue in macronodular adrenocortical hyperplasia: progression of tumorigenesis in a disorder associated with multiple benign lesions. J. Clin. Endocrinol. Metab. 2011, 96:E728-E738.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Almeida, M.Q.1
Harran, M.2
Bimpaki, E.I.3
Hsiao, H.-P.4
Horvath, A.5
Cheadle, C.6
Watkins, T.7
Nesterova, M.8
Stratakis, C.A.9
-
5
-
-
79952070409
-
How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?
-
Almeida M.Q., Stratakis C.A. How does cAMP/protein kinase A signaling lead to tumors in the adrenal cortex and other tissues?. Mol. Cell. Endocrinol. 2011, 336:162-168.
-
(2011)
Mol. Cell. Endocrinol.
, vol.336
, pp. 162-168
-
-
Almeida, M.Q.1
Stratakis, C.A.2
-
6
-
-
84859529956
-
Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations
-
Almeida M.Q., Azevedo M., Xekouki P., Horvath A., Bimpaki E., Collins M., Bhattacharyya N., Karaviti L.P., Jeha G.S., Cheadle C., Watkins T., Bourdeau I., Nesetrova M., Stratakis C.A. Activation of cyclic AMP signaling leads to different pathway alterations in lesions of the adrenal cortex caused by germline PRKAR1A defects versus those due to somatic GNAS mutations. J. Clin. Endocrinol. Metab. 2012, 97:E687-E993.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Almeida, M.Q.1
Azevedo, M.2
Xekouki, P.3
Horvath, A.4
Bimpaki, E.5
Collins, M.6
Bhattacharyya, N.7
Karaviti, L.P.8
Jeha, G.S.9
Cheadle, C.10
Watkins, T.11
Bourdeau, I.12
Nesetrova, M.13
Stratakis, C.A.14
-
7
-
-
0036293582
-
The essential role of RI alpha in the maintenance of regulated PKA activity
-
Amieux P.S., McKnight G.S. The essential role of RI alpha in the maintenance of regulated PKA activity. Ann. N. Y. Acad. Sci. 2002, 968:75-95.
-
(2002)
Ann. N. Y. Acad. Sci.
, vol.968
, pp. 75-95
-
-
Amieux, P.S.1
McKnight, G.S.2
-
8
-
-
84856799660
-
A large family with Carney complex caused by the S147G PRKAR1A mutation shows a unique spectrum of disease including adrenocortical cancer
-
Anselmo J., Medeiros S., Carneiro V., Greene E., Levy I., Nesterova M., Lyssikatos C., Horvath A., Carney J.A., Stratakis C.A. A large family with Carney complex caused by the S147G PRKAR1A mutation shows a unique spectrum of disease including adrenocortical cancer. J. Clin. Endocrinol. Metab. 2012, 97:351-359.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
, pp. 351-359
-
-
Anselmo, J.1
Medeiros, S.2
Carneiro, V.3
Greene, E.4
Levy, I.5
Nesterova, M.6
Lyssikatos, C.7
Horvath, A.8
Carney, J.A.9
Stratakis, C.A.10
-
9
-
-
83155177174
-
Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors
-
Arlt W., Biehl M., Taylor A.E., Hahner S., Libé R., Hughes B.A., Schneider P., Smith D.J., Stiekema H., Krone N., Porfiri E., Opocher G., Bertherat J., Mantero F., Allolio B., Terzolo M., Nightingale P., Shackleton C.H., Bertagna X., Fassnacht M., Stewart P.M. Urine steroid metabolomics as a biomarker tool for detecting malignancy in adrenal tumors. J. Clin. Endocrinol. Metab. 2011, 96:3775-3784.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 3775-3784
-
-
Arlt, W.1
Biehl, M.2
Taylor, A.E.3
Hahner, S.4
Libé, R.5
Hughes, B.A.6
Schneider, P.7
Smith, D.J.8
Stiekema, H.9
Krone, N.10
Porfiri, E.11
Opocher, G.12
Bertherat, J.13
Mantero, F.14
Allolio, B.15
Terzolo, M.16
Nightingale, P.17
Shackleton, C.H.18
Bertagna, X.19
Fassnacht, M.20
Stewart, P.M.21
more..
-
10
-
-
44449164338
-
Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function
-
Arnaud-Lopez L., Usala G., Ceresini G., Mitchell B.D., Pilia M.G., Piras M.G., Sestu N., Maschio A., Busonero F., Albai G., Dei M., Lai S., Mulas A., Crisponi L., Tanaka T., Bandinelli S., Guralnik J.M., Loi A., Balaci L., Sole G., Prinzis A., Mariotti S., Shuldiner A.R., Cao A., Schlessinger D., Uda M., Abecasis G.R., Nagaraja R., Sanna S., Naitza S. Phosphodiesterase 8B gene variants are associated with serum TSH levels and thyroid function. Am. J. Hum. Genet. 2008, 82:1270-1280.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 1270-1280
-
-
Arnaud-Lopez, L.1
Usala, G.2
Ceresini, G.3
Mitchell, B.D.4
Pilia, M.G.5
Piras, M.G.6
Sestu, N.7
Maschio, A.8
Busonero, F.9
Albai, G.10
Dei, M.11
Lai, S.12
Mulas, A.13
Crisponi, L.14
Tanaka, T.15
Bandinelli, S.16
Guralnik, J.M.17
Loi, A.18
Balaci, L.19
Sole, G.20
Prinzis, A.21
Mariotti, S.22
Shuldiner, A.R.23
Cao, A.24
Schlessinger, D.25
Uda, M.26
Abecasis, G.R.27
Nagaraja, R.28
Sanna, S.29
Naitza, S.30
more..
-
11
-
-
41549089945
-
SNP arrays in heterogeneous tissue: highly accurate collection of both germline and somatic genetic information from unpaired single tumor samples
-
Assié G., Laframboise T., Platzer P., Bertherat J., Stratakis C.A., Eng C. SNP arrays in heterogeneous tissue: highly accurate collection of both germline and somatic genetic information from unpaired single tumor samples. Am. J. Hum. Genet. 2008, 82:903-915.
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 903-915
-
-
Assié, G.1
Laframboise, T.2
Platzer, P.3
Bertherat, J.4
Stratakis, C.A.5
Eng, C.6
-
12
-
-
0038721027
-
Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity
-
Bertherat J., Groussin L., Sandrini F., Matyakhina L., Bei T., Stergiopoulos S., Papageorgiou T., Bourdeau I., Kirschner L.S., Vincent-Dejean C., Perlemoine K., Gicquel C., Bertagna X., Stratakis C.A. Molecular and functional analysis of PRKAR1A and its locus (17q22-24) in sporadic adrenocortical tumors: 17q losses, somatic mutations, and protein kinase A expression and activity. Cancer Res. 2003, 63:5308-5319.
-
(2003)
Cancer Res.
, vol.63
, pp. 5308-5319
-
-
Bertherat, J.1
Groussin, L.2
Sandrini, F.3
Matyakhina, L.4
Bei, T.5
Stergiopoulos, S.6
Papageorgiou, T.7
Bourdeau, I.8
Kirschner, L.S.9
Vincent-Dejean, C.10
Perlemoine, K.11
Gicquel, C.12
Bertagna, X.13
Stratakis, C.A.14
-
13
-
-
66749184725
-
Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes
-
Bertherat J., Horvath A., Groussin L., Grabar S., Boikos S., Cazabat L., Libe R., René-Corail F., Stergiopoulos S., Bourdeau I., Bei T., Clauser E., Calender A., Kirschner L.S., Bertagna X., Carney J.A., Stratakis C.A. Mutations in regulatory subunit type 1A of cyclic adenosine 5'-monophosphate-dependent protein kinase (PRKAR1A): phenotype analysis in 353 patients and 80 different genotypes. J. Clin. Endocrinol. Metab. 2009, 94:2085-2089.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 2085-2089
-
-
Bertherat, J.1
Horvath, A.2
Groussin, L.3
Grabar, S.4
Boikos, S.5
Cazabat, L.6
Libe, R.7
René-Corail, F.8
Stergiopoulos, S.9
Bourdeau, I.10
Bei, T.11
Clauser, E.12
Calender, A.13
Kirschner, L.S.14
Bertagna, X.15
Carney, J.A.16
Stratakis, C.A.17
-
14
-
-
77952300541
-
Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development
-
Berthon A., Sahut-Barnola I., Lambert-Langlais S., de Joussineau C., Damon-Soubeyrand C., Louiset E., Taketo M.M., Tissier F., Bertherat J., Lefrançois-Martinez A.M., Martinez A., Val P. Constitutive beta-catenin activation induces adrenal hyperplasia and promotes adrenal cancer development. Hum. Mol. Genet. 2010, 19:1561-1576.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 1561-1576
-
-
Berthon, A.1
Sahut-Barnola, I.2
Lambert-Langlais, S.3
de Joussineau, C.4
Damon-Soubeyrand, C.5
Louiset, E.6
Taketo, M.M.7
Tissier, F.8
Bertherat, J.9
Lefrançois-Martinez, A.M.10
Martinez, A.11
Val, P.12
-
15
-
-
84876088145
-
Wnt/β-catenin signalling in adrenal physiology and tumour development
-
in press
-
Berthon, A., Martinez, A., Bertherat, J., Val, P., in press. Wnt/β-catenin signalling in adrenal physiology and tumour development. Mol. Cell. Endocrinol.
-
Mol. Cell. Endocrinol.
-
-
Berthon, A.1
Martinez, A.2
Bertherat, J.3
Val, P.4
-
16
-
-
0034524497
-
Cortisol producing adrenal adenoma - a new manifestation of Gardner's syndrome
-
Beuschlein F., Reincke M., Königer M., D'Orazio D., Dobbie Z., Rump L.C. Cortisol producing adrenal adenoma - a new manifestation of Gardner's syndrome. Endocr. Res. 2000, 26:783-790.
-
(2000)
Endocr. Res.
, vol.26
, pp. 783-790
-
-
Beuschlein, F.1
Reincke, M.2
Königer, M.3
D'Orazio, D.4
Dobbie, Z.5
Rump, L.C.6
-
17
-
-
0032523095
-
Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells
-
Bianco P., Kuznetsov S.A., Riminucci M., Fisher L.W., Spiegel A.M., Robey P.G. Reproduction of human fibrous dysplasia of bone in immunocompromised mice by transplanted mosaics of normal and Gsalpha-mutated skeletal progenitor cells. J. Clin. Invest. 1998, 101:1737-1744.
-
(1998)
J. Clin. Invest.
, vol.101
, pp. 1737-1744
-
-
Bianco, P.1
Kuznetsov, S.A.2
Riminucci, M.3
Fisher, L.W.4
Spiegel, A.M.5
Robey, P.G.6
-
18
-
-
0033371108
-
Inhibition of prostaglandin synthesis reduces cyclic AMP levels and inhibits chondrogenesis in cultured chick limb mesenchyme
-
Biddulph D.M., Dozier M.M., Capehart A.A. Inhibition of prostaglandin synthesis reduces cyclic AMP levels and inhibits chondrogenesis in cultured chick limb mesenchyme. Methods Cell Sci. 2000, 22:9-16.
-
(2000)
Methods Cell Sci.
, vol.22
, pp. 9-16
-
-
Biddulph, D.M.1
Dozier, M.M.2
Capehart, A.A.3
-
19
-
-
67650767017
-
Abnormalities of cAMP signaling are present in adrenocortical lesions associated with corticotropin-independent Cushing syndrome despite the absence of mutations in known genes
-
Bimpaki E., Nesterova M., Stratakis C.A. Abnormalities of cAMP signaling are present in adrenocortical lesions associated with corticotropin-independent Cushing syndrome despite the absence of mutations in known genes. Eur. J. Endocrinol. 2009, 161:153-161.
-
(2009)
Eur. J. Endocrinol.
, vol.161
, pp. 153-161
-
-
Bimpaki, E.1
Nesterova, M.2
Stratakis, C.A.3
-
20
-
-
77952627699
-
MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumorigenesis
-
Bimpaki E.I., Iliopoulos D., Moraitis A., Stratakis C.A. MicroRNA signature in massive macronodular adrenocortical disease and implications for adrenocortical tumorigenesis. Clin. Endocrinol. (Oxf) 2010, 72:744-751.
-
(2010)
Clin. Endocrinol. (Oxf)
, vol.72
, pp. 744-751
-
-
Bimpaki, E.I.1
Iliopoulos, D.2
Moraitis, A.3
Stratakis, C.A.4
-
21
-
-
77952495406
-
Prostaglandins in bone: bad cop, good cop?
-
Blackwell K.A., Raisz L.G., Pilbeam C.C. Prostaglandins in bone: bad cop, good cop?. Trends Endocrinol. Metab. 2010, 21:294-301.
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 294-301
-
-
Blackwell, K.A.1
Raisz, L.G.2
Pilbeam, C.C.3
-
22
-
-
56649117453
-
A 2.3Mb deletion of 17q24.2-q24.3 associated with 'Carney Complex plus'
-
Blyth M., Huang S., Maloney V., Crolla J.A., Karen Temple.I. A 2.3Mb deletion of 17q24.2-q24.3 associated with 'Carney Complex plus'. Eur. J. Med. Genet. 2008, 51:672-678.
-
(2008)
Eur. J. Med. Genet.
, vol.51
, pp. 672-678
-
-
Blyth, M.1
Huang, S.2
Maloney, V.3
Crolla, J.A.4
Karen, T.5
-
23
-
-
45549099523
-
Phosphodiesterase 11A expression in the adrenal cortex, primary pigmented nodular adrenocortical disease and other corticotropin-independent lesions
-
Boikos A., Horvath A., Heyerdahl S., Stein E., Robinson-White A., Bossis I., Bertherat J., Stratakis C.A. Phosphodiesterase 11A expression in the adrenal cortex, primary pigmented nodular adrenocortical disease and other corticotropin-independent lesions. Horm. Metab. Res. 2008, 40:347-353.
-
(2008)
Horm. Metab. Res.
, vol.40
, pp. 347-353
-
-
Boikos, A.1
Horvath, A.2
Heyerdahl, S.3
Stein, E.4
Robinson-White, A.5
Bossis, I.6
Bertherat, J.7
Stratakis, C.A.8
-
24
-
-
79551555038
-
Cancer stem cell niche: the place to be
-
Borovski T., De Sousa E., Melo F., Vermeulen L., Medema J.P. Cancer stem cell niche: the place to be. Cancer Res. 2011, 71:634-639.
-
(2011)
Cancer Res.
, vol.71
, pp. 634-639
-
-
Borovski, T.1
De Sousa, E.2
Melo, F.3
Vermeulen, L.4
Medema, J.P.5
-
25
-
-
9444247656
-
Minireview: PRKAR1A: normal and abnormal functions
-
5452-5428
-
Bossis I., Stratakis C.A. Minireview: PRKAR1A: normal and abnormal functions. Endocrinology 2004, 145. 5452-5428.
-
(2004)
Endocrinology
, vol.145
-
-
Bossis, I.1
Stratakis, C.A.2
-
26
-
-
0027934280
-
Activating mutation in the stimulatory guanine nucleotide-binding protein in an infant with Cushing's syndrome and nodular adrenal hyperplasia
-
Boston B.A., Mandel S., LaFranchi S., Bliziotes M. Activating mutation in the stimulatory guanine nucleotide-binding protein in an infant with Cushing's syndrome and nodular adrenal hyperplasia. J. Clin. Endocrinol. Metab. 1994, 79:890-893.
-
(1994)
J. Clin. Endocrinol. Metab.
, vol.79
, pp. 890-893
-
-
Boston, B.A.1
Mandel, S.2
LaFranchi, S.3
Bliziotes, M.4
-
27
-
-
84857623168
-
Prevalence, clinical, and molecular correlates of KCNJ5 mutations in primary aldosteronism
-
Boulkroun S., Beuschlein F., Rossi G.P., Golib-Dzib J.F., Fischer E., Amar L., Mulatero P., Samson-Couterie B., Hahner S., Quinkler M., Fallo F., Letizia C., Allolio B., Ceolotto G., Cicala M.V., Lang K., Lefebvre H., Lenzini L., Maniero C., Monticone S., Perrocheau M., Pilon C., Plouin P.F., Rayes N., Seccia T.M., Veglio F., Williams T.A., Zinnamosca L., Mantero F., Benecke A., Jeunemaitre X., Reincke M., Zennaro M.C. Prevalence, clinical, and molecular correlates of KCNJ5 mutations in primary aldosteronism. Hypertension 2012, 59:592-598.
-
(2012)
Hypertension
, vol.59
, pp. 592-598
-
-
Boulkroun, S.1
Beuschlein, F.2
Rossi, G.P.3
Golib-Dzib, J.F.4
Fischer, E.5
Amar, L.6
Mulatero, P.7
Samson-Couterie, B.8
Hahner, S.9
Quinkler, M.10
Fallo, F.11
Letizia, C.12
Allolio, B.13
Ceolotto, G.14
Cicala, M.V.15
Lang, K.16
Lefebvre, H.17
Lenzini, L.18
Maniero, C.19
Monticone, S.20
Perrocheau, M.21
Pilon, C.22
Plouin, P.F.23
Rayes, N.24
Seccia, T.M.25
Veglio, F.26
Williams, T.A.27
Zinnamosca, L.28
Mantero, F.29
Benecke, A.30
Jeunemaitre, X.31
Reincke, M.32
Zennaro, M.C.33
more..
-
28
-
-
0041381386
-
Primary pigmented nodular adrenocortical disease: paradoxical responses of cortisol secretion to dexamethasone occur in vitro and are associated with increased expression of the glucocorticoid receptor
-
Bourdeau I., Lacroix A., Schürch W., Caron P., Antakly T., Stratakis C.A. Primary pigmented nodular adrenocortical disease: paradoxical responses of cortisol secretion to dexamethasone occur in vitro and are associated with increased expression of the glucocorticoid receptor. J. Clin. Endocrinol. Metab. 2003, 88:3931-3937.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 3931-3937
-
-
Bourdeau, I.1
Lacroix, A.2
Schürch, W.3
Caron, P.4
Antakly, T.5
Stratakis, C.A.6
-
29
-
-
1542741588
-
Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators
-
Bourdeau I., Antonini S.R., Lacroix A., Kirschner L.S., Matyakhina L., Lorang D., Libutti S.K., Stratakis C.A. Gene array analysis of macronodular adrenal hyperplasia confirms clinical heterogeneity and identifies several candidate genes as molecular mediators. Oncogene 2004, 23:1575-1585.
-
(2004)
Oncogene
, vol.23
, pp. 1575-1585
-
-
Bourdeau, I.1
Antonini, S.R.2
Lacroix, A.3
Kirschner, L.S.4
Matyakhina, L.5
Lorang, D.6
Libutti, S.K.7
Stratakis, C.A.8
-
30
-
-
33748748991
-
17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia
-
Bourdeau I., Matyakhina L., Stergiopoulos S.G., Sandrini F., Boikos S., Stratakis C.A. 17q22-24 chromosomal losses and alterations of protein kinase a subunit expression and activity in adrenocorticotropin-independent macronodular adrenal hyperplasia. J. Clin. Endocrinol. Metab. 2006, 91:3626-3632.
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, pp. 3626-3632
-
-
Bourdeau, I.1
Matyakhina, L.2
Stergiopoulos, S.G.3
Sandrini, F.4
Boikos, S.5
Stratakis, C.A.6
-
31
-
-
34247573015
-
Adrenocorticotropic hormone-independent Cushing's syndrome
-
Bourdeau I., Lampron A., Costa M.H., Tadjine M., Lacroix A. Adrenocorticotropic hormone-independent Cushing's syndrome. Curr. Opin. Endocrinol. Diabetes Obes. 2007, 14:219-225.
-
(2007)
Curr. Opin. Endocrinol. Diabetes Obes.
, vol.14
, pp. 219-225
-
-
Bourdeau, I.1
Lampron, A.2
Costa, M.H.3
Tadjine, M.4
Lacroix, A.5
-
32
-
-
0029021176
-
Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase
-
Brandon E.P., Zhuo M., Huang Y.Y., Qi M., Gerhold K.A., Burton K.A., Kandel E.R., McKnight G.S., Idzerda R.L. Hippocampal long-term depression and depotentiation are defective in mice carrying a targeted disruption of the gene encoding the RI beta subunit of cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 1995, 92:8851-8855.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8851-8855
-
-
Brandon, E.P.1
Zhuo, M.2
Huang, Y.Y.3
Qi, M.4
Gerhold, K.A.5
Burton, K.A.6
Kandel, E.R.7
McKnight, G.S.8
Idzerda, R.L.9
-
34
-
-
0030930754
-
Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase
-
Burton K.A., Johnson B.D., Hausken Z.E., Westenbroek R.E., Idzerda R.L., Scheuer T., Scott J.D., Catterall W.A., McKnight G.S. Type II regulatory subunits are not required for the anchoring-dependent modulation of Ca2+ channel activity by cAMP-dependent protein kinase. Proc. Natl. Acad. Sci. USA 1997, 94:11067-11072.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 11067-11072
-
-
Burton, K.A.1
Johnson, B.D.2
Hausken, Z.E.3
Westenbroek, R.E.4
Idzerda, R.L.5
Scheuer, T.6
Scott, J.D.7
Catterall, W.A.8
McKnight, G.S.9
-
35
-
-
0017736213
-
The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma
-
Carney J.A., Sheps S.G., Go V.L., Gordon H. The triad of gastric leiomyosarcoma, functioning extra-adrenal paraganglioma and pulmonary chondroma. N. Engl. J. Med. 1977, 296:1517-1518.
-
(1977)
N. Engl. J. Med.
, vol.296
, pp. 1517-1518
-
-
Carney, J.A.1
Sheps, S.G.2
Go, V.L.3
Gordon, H.4
-
36
-
-
0022397926
-
The complex of myxomas, spotty pigmentation, and endocrine overactivity
-
Carney J.A., Gordon H., Carpenter P.C., Shenoy B.V., Go V.L. The complex of myxomas, spotty pigmentation, and endocrine overactivity. Medicine (Baltimore). 1985, 64:270-283.
-
(1985)
Medicine (Baltimore).
, vol.64
, pp. 270-283
-
-
Carney, J.A.1
Gordon, H.2
Carpenter, P.C.3
Shenoy, B.V.4
Go, V.L.5
-
37
-
-
0028798605
-
The Carney complex (myxomas, spotty pigmentation, endocrine overactivity, and schwannomas)
-
Carney J.A. The Carney complex (myxomas, spotty pigmentation, endocrine overactivity, and schwannomas). Dermatol. Clin. 1995, 13:19-26.
-
(1995)
Dermatol. Clin.
, vol.13
, pp. 19-26
-
-
Carney, J.A.1
-
38
-
-
0036499042
-
Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney Triad
-
Carney J.A., Stratakis C.A. Familial paraganglioma and gastric stromal sarcoma: a new syndrome distinct from the Carney Triad. Am. J. Med. Genet. 2002, 108:132-139.
-
(2002)
Am. J. Med. Genet.
, vol.108
, pp. 132-139
-
-
Carney, J.A.1
Stratakis, C.A.2
-
39
-
-
77950204638
-
Familial micronodular adrenocortical disease, Cushing syndrome, and mutations of the gene encoding phosphodiesterase 11A4 (PDE11A)
-
Carney J.A., Gaillard R.C., Bertherat J., Stratakis C.A. Familial micronodular adrenocortical disease, Cushing syndrome, and mutations of the gene encoding phosphodiesterase 11A4 (PDE11A). Am. J. Surg. Pathol. 2010, 34:547-555.
-
(2010)
Am. J. Surg. Pathol.
, vol.34
, pp. 547-555
-
-
Carney, J.A.1
Gaillard, R.C.2
Bertherat, J.3
Stratakis, C.A.4
-
40
-
-
81155161059
-
Primary bimorphic adrenocortical disease: cause of hypercortisolism in McCune-Albright syndrome
-
Carney J.A., Young W.F., Stratakis C.A. Primary bimorphic adrenocortical disease: cause of hypercortisolism in McCune-Albright syndrome. Am. J. Surg. Pathol. 2011, 35:1311-1326.
-
(2011)
Am. J. Surg. Pathol.
, vol.35
, pp. 1311-1326
-
-
Carney, J.A.1
Young, W.F.2
Stratakis, C.A.3
-
41
-
-
80052031185
-
Further study of chromosome 7p22 to identify the molecular basis of familial hyperaldosteronism type II
-
Carss K.J., Stowasser M., Gordon R.D., O'Shaughnessy K.M. Further study of chromosome 7p22 to identify the molecular basis of familial hyperaldosteronism type II. J. Hum. Hypertens. 2011, 25:560-564.
-
(2011)
J. Hum. Hypertens.
, vol.25
, pp. 560-564
-
-
Carss, K.J.1
Stowasser, M.2
Gordon, R.D.3
O'Shaughnessy, K.M.4
-
42
-
-
79951506090
-
K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension
-
Choi M., Scholl U.I., Yue P., Björklund P., Zhao B., Nelson-Williams C., Ji W., Cho Y., Patel A., Men C.J., Lolis E., Wisgerhof M.V., Geller D.S., Mane S., Hellman P., Westin G., Åkerström G., Wang W., Carling T., Lifton R.P. K+ channel mutations in adrenal aldosterone-producing adenomas and hereditary hypertension. Science 2011, 331:768-772.
-
(2011)
Science
, vol.331
, pp. 768-772
-
-
Choi, M.1
Scholl, U.I.2
Yue, P.3
Björklund, P.4
Zhao, B.5
Nelson-Williams, C.6
Ji, W.7
Cho, Y.8
Patel, A.9
Men, C.J.10
Lolis, E.11
Wisgerhof, M.V.12
Geller, D.S.13
Mane, S.14
Hellman, P.15
Westin, G.16
Åkerström, G.17
Wang, W.18
Carling, T.19
Lifton, R.P.20
more..
-
43
-
-
78650057361
-
The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways
-
Chun K.S., Lao H.C., Langenbach R. The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and {beta}-arrestin1-dependent signaling pathways. J. Biol. Chem. 2010, 285:39672-39681.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 39672-39681
-
-
Chun, K.S.1
Lao, H.C.2
Langenbach, R.3
-
44
-
-
34447265905
-
Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling
-
Conti M., Beavo J. Biochemistry and physiology of cyclic nucleotide phosphodiesterases: essential components in cyclic nucleotide signaling. Annu. Rev. Biochem. 2007, 76:481-511.
-
(2007)
Annu. Rev. Biochem.
, vol.76
, pp. 481-511
-
-
Conti, M.1
Beavo, J.2
-
45
-
-
0029737861
-
Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A
-
Cummings D.E., Brandon E.P., Planas J.V., Motamed K., Idzerda R.L., McKnight G.S. Genetically lean mice result from targeted disruption of the RII beta subunit of protein kinase A. Nature 1996, 382:622-626.
-
(1996)
Nature
, vol.382
, pp. 622-626
-
-
Cummings, D.E.1
Brandon, E.P.2
Planas, J.V.3
Motamed, K.4
Idzerda, R.L.5
McKnight, G.S.6
-
46
-
-
38349105880
-
Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice
-
Czyzyk T.A., Sikorski M.A., Yang L., McKnight G.S. Disruption of the RIIbeta subunit of PKA reverses the obesity syndrome of Agouti lethal yellow mice. Proc. Natl. Acad. Sci. USA 2008, 105:276-281.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 276-281
-
-
Czyzyk, T.A.1
Sikorski, M.A.2
Yang, L.3
McKnight, G.S.4
-
47
-
-
33751022236
-
Gastrointestinal stromal tumor: update. Klin
-
Daum O., Vanecek T., Sima R., Michal M. Gastrointestinal stromal tumor: update. Klin. Onkologie 2006, 19:203-211.
-
(2006)
Onkologie
, vol.19
, pp. 203-211
-
-
Daum, O.1
Vanecek, T.2
Sima, R.3
Michal, M.4
-
48
-
-
21544469970
-
Expression of PDE11A in normal and malignant human tissues
-
D'Andrea M.R., Qiu Y., Haynes-Johnson D., Bhattacharjee S., Kraft P., Lundeen S. Expression of PDE11A in normal and malignant human tissues. J. Histochem. Cytochem. 2005, 53:895-903.
-
(2005)
J. Histochem. Cytochem.
, vol.53
, pp. 895-903
-
-
D'Andrea, M.R.1
Qiu, Y.2
Haynes-Johnson, D.3
Bhattacharjee, S.4
Kraft, P.5
Lundeen, S.6
-
49
-
-
84876080654
-
The cAMP pathway and the control of adrenocortical development and growth.
-
in press
-
de Joussineau, C., Sahut-Barnola, I., Levy, I., Saloustros, E., Val, P., Stratakis, C.A., Martinez, A., in press. The cAMP pathway and the control of adrenocortical development and growth. Mol. Cell. Endocrinol.
-
Mol. Cell. Endocrinol.
-
-
De Joussineau, C.1
Sahut-Barnola, I.2
Levy, I.3
Saloustros, E.4
Val, P.5
Stratakis, C.A.6
Martinez, A.7
-
50
-
-
78149254991
-
Regulation of cAMP-dependent protein kinases: the human protein kinase X (PrKX) reveals the role of the catalytic subunit alphaH-alphaI loop
-
Diskar M., Zenn H.M., Kaupisch A., Kaufholz M., Brockmeyer S., Sohmen D., Berrera M., Zaccolo M., Boshart M., Herberg F.W., Prinz A. Regulation of cAMP-dependent protein kinases: the human protein kinase X (PrKX) reveals the role of the catalytic subunit alphaH-alphaI loop. J. Biol. Chem. 2010, 285:35910-35918.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 35910-35918
-
-
Diskar, M.1
Zenn, H.M.2
Kaupisch, A.3
Kaufholz, M.4
Brockmeyer, S.5
Sohmen, D.6
Berrera, M.7
Zaccolo, M.8
Boshart, M.9
Herberg, F.W.10
Prinz, A.11
-
51
-
-
38549127858
-
Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose
-
Dov A., Abramovitch E., Warwar N., Nesher R. Diminished phosphodiesterase-8B potentiates biphasic insulin response to glucose. Endocrinology 2008, 149:741-748.
-
(2008)
Endocrinology
, vol.149
, pp. 741-748
-
-
Dov, A.1
Abramovitch, E.2
Warwar, N.3
Nesher, R.4
-
52
-
-
10844268664
-
Genomic structure of the human gene for protein kinase A regulatory subunit R1-beta (PRKAR1B) on 7p22: no evidence for mutations in familial hyperaldosteronism type II in a large affected kindred
-
Elphinstone M.S., Gordon R.D., So A., Jeske Y.W., Stratakis C.A., Stowasser M. Genomic structure of the human gene for protein kinase A regulatory subunit R1-beta (PRKAR1B) on 7p22: no evidence for mutations in familial hyperaldosteronism type II in a large affected kindred. Clin. Endocrinol. (Oxf) 2004, 61:716-723.
-
(2004)
Clin. Endocrinol. (Oxf)
, vol.61
, pp. 716-723
-
-
Elphinstone, M.S.1
Gordon, R.D.2
So, A.3
Jeske, Y.W.4
Stratakis, C.A.5
Stowasser, M.6
-
53
-
-
0036302235
-
Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes
-
Feldmann J., Prieur A.M., Quartier P., Berquin P., Certain S., Cortis E., Teillac-Hamel D., Fischer A., de Saint Basile G. Chronic infantile neurological cutaneous and articular syndrome is caused by mutations in CIAS1, a gene highly expressed in polymorphonuclear cells and chondrocytes. Am. J. Hum. Genet. 2002, 71:198-203.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 198-203
-
-
Feldmann, J.1
Prieur, A.M.2
Quartier, P.3
Berquin, P.4
Certain, S.5
Cortis, E.6
Teillac-Hamel, D.7
Fischer, A.8
de Saint Basile, G.9
-
54
-
-
78650866382
-
SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors
-
Gaal J., Stratakis C.A., Carney J.A., Ball E.R., Korpershoek E., Lodish M.B., Levy I., Xekouki P., van Nederveen F.H., den Bakker M.A., O'Sullivan M., Dinjens W.N., de Krijger R.R. SDHB immunohistochemistry: a useful tool in the diagnosis of Carney-Stratakis and Carney triad gastrointestinal stromal tumors. Mod. Pathol. 2011, 24:147-151.
-
(2011)
Mod. Pathol.
, vol.24
, pp. 147-151
-
-
Gaal, J.1
Stratakis, C.A.2
Carney, J.A.3
Ball, E.R.4
Korpershoek, E.5
Lodish, M.B.6
Levy, I.7
Xekouki, P.8
van Nederveen, F.H.9
den Bakker, M.A.10
O'Sullivan, M.11
Dinjens, W.N.12
de Krijger, R.R.13
-
55
-
-
66149179265
-
Familial vasopressin-sensitive ACTH-independent macronodular adrenal hyperplasia (VPs-AIMAH): clinical studies of three kindreds
-
Gagliardi L., Hotu C., Casey G., Braund W.J., Ling K.H., Dodd T., Manavis J., Devitt P.G., Cutfield R., Rudzki Z., Scott H.S., Torpy D.J. Familial vasopressin-sensitive ACTH-independent macronodular adrenal hyperplasia (VPs-AIMAH): clinical studies of three kindreds. Clin. Endocrinol. (Oxf) 2009, 70:883-891.
-
(2009)
Clin. Endocrinol. (Oxf)
, vol.70
, pp. 883-891
-
-
Gagliardi, L.1
Hotu, C.2
Casey, G.3
Braund, W.J.4
Ling, K.H.5
Dodd, T.6
Manavis, J.7
Devitt, P.G.8
Cutfield, R.9
Rudzki, Z.10
Scott, H.S.11
Torpy, D.J.12
-
56
-
-
0037409401
-
Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans
-
Gamanuma M., Yuasa K., Sasaki T., Sakurai N., Kotera J., Omori K. Comparison of enzymatic characterization and gene organization of cyclic nucleotide phosphodiesterase 8 family in humans. Cell. Signal. 2003, 15:565-574.
-
(2003)
Cell. Signal.
, vol.15
, pp. 565-574
-
-
Gamanuma, M.1
Yuasa, K.2
Sasaki, T.3
Sakurai, N.4
Kotera, J.5
Omori, K.6
-
57
-
-
84856082581
-
Adrenal involvement in MEN1. Analysis of 715 cases from the Groupe d'etude des Tumeurs Endocrines database
-
Gatta-Cherifi B., Chabre O., Murat A., Niccoli P., Cardot-Bauters C., Rohmer V., Young J., Delemer B., Du Boullay H., Verger M.F., Kuhn J.M., Sadoul J.L., Ruszniewski P., Beckers A., Monsaingeon M., Baudin E., Goudet P., Tabarin A. Adrenal involvement in MEN1. Analysis of 715 cases from the Groupe d'etude des Tumeurs Endocrines database. Eur. J. Endocrinol. 2012, 166:269-279.
-
(2012)
Eur. J. Endocrinol.
, vol.166
, pp. 269-279
-
-
Gatta-Cherifi, B.1
Chabre, O.2
Murat, A.3
Niccoli, P.4
Cardot-Bauters, C.5
Rohmer, V.6
Young, J.7
Delemer, B.8
Du Boullay, H.9
Verger, M.F.10
Kuhn, J.M.11
Sadoul, J.L.12
Ruszniewski, P.13
Beckers, A.14
Monsaingeon, M.15
Baudin, E.16
Goudet, P.17
Tabarin, A.18
-
58
-
-
53749096474
-
Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors
-
Gaujoux S., Tissier F., Groussin L., Libé R., Ragazzon B., Launay P., Audebourg A., Dousset B., Bertagna X., Bertherat J. Wnt/beta-catenin and 3',5'-cyclic adenosine 5'-monophosphate/protein kinase A signaling pathways alterations and somatic beta-catenin gene mutations in the progression of adrenocortical tumors. J. Clin. Endocrinol. Metab. 2008, 93:4135-4140.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 4135-4140
-
-
Gaujoux, S.1
Tissier, F.2
Groussin, L.3
Libé, R.4
Ragazzon, B.5
Launay, P.6
Audebourg, A.7
Dousset, B.8
Bertagna, X.9
Bertherat, J.10
-
59
-
-
78049477329
-
Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers
-
Gaujoux S., Pinson S., Gimenez-Roqueplo A.P., Amar L., Ragazzon B., Launay P., Meatchi T., Libé R., Bertagna X., Audebourg A., Zucman-Rossi J., Tissier F., Bertherat J. Inactivation of the APC gene is constant in adrenocortical tumors from patients with familial adenomatous polyposis but not frequent in sporadic adrenocortical cancers. Clin. Cancer Res. 2010, 16:5133-5141.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 5133-5141
-
-
Gaujoux, S.1
Pinson, S.2
Gimenez-Roqueplo, A.P.3
Amar, L.4
Ragazzon, B.5
Launay, P.6
Meatchi, T.7
Libé, R.8
Bertagna, X.9
Audebourg, A.10
Zucman-Rossi, J.11
Tissier, F.12
Bertherat, J.13
-
60
-
-
80655130415
-
Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association
-
Gaujoux S., Tissier F., Ragazzon B., Rebours V., Saloustros E., Perlemoine K., Vincent-Dejean C., Meurette G., Cassagnau E., Dousset B., Bertagna X., Horvath A., Terris B., Carney J.A., Stratakis C.A., Bertherat J. Pancreatic ductal and acinar cell neoplasms in Carney complex: a possible new association. J. Clin. Endocrinol. Metab. 2011, 96:E1888-E1895.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Gaujoux, S.1
Tissier, F.2
Ragazzon, B.3
Rebours, V.4
Saloustros, E.5
Perlemoine, K.6
Vincent-Dejean, C.7
Meurette, G.8
Cassagnau, E.9
Dousset, B.10
Bertagna, X.11
Horvath, A.12
Terris, B.13
Carney, J.A.14
Stratakis, C.A.15
Bertherat, J.16
-
61
-
-
49249091443
-
A novel form of human Mendelian hypertension featuring nonglucocorticoid-remediable aldosteronism
-
Geller D.S., Zhang J., Wisgerhof M.V., Shackleton C., Kashgarian M., Lifton R.P. A novel form of human Mendelian hypertension featuring nonglucocorticoid-remediable aldosteronism. J. Clin. Endocrinol. Metab. 2008, 93:3117-3123.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 3117-3123
-
-
Geller, D.S.1
Zhang, J.2
Wisgerhof, M.V.3
Shackleton, C.4
Kashgarian, M.5
Lifton, R.P.6
-
62
-
-
54049112731
-
A novel PRKAR1A mutation associated with hepatocellular carcinoma in a young patient and a variable Carney complex phenotype in affected subjects in older generations
-
Gennari M., Stratakis C.A., Hovarth A., Pirazzoli P., Cicognani A. A novel PRKAR1A mutation associated with hepatocellular carcinoma in a young patient and a variable Carney complex phenotype in affected subjects in older generations. Clin. Endocrinol. (Oxf) 2008, 69:751-755.
-
(2008)
Clin. Endocrinol. (Oxf)
, vol.69
, pp. 751-755
-
-
Gennari, M.1
Stratakis, C.A.2
Hovarth, A.3
Pirazzoli, P.4
Cicognani, A.5
-
63
-
-
79951719798
-
Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new syndrome
-
Ghayee H.K., Rege J., Watumull L.M., Nwariaku F.E., Carrick K.S., Rainey W.E., Miller W.L., Auchus R.J. Clinical, biochemical, and molecular characterization of macronodular adrenocortical hyperplasia of the zona reticularis: a new syndrome. J. Clin. Endocrinol. Metab. 2011, 96:E243-E250.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Ghayee, H.K.1
Rege, J.2
Watumull, L.M.3
Nwariaku, F.E.4
Carrick, K.S.5
Rainey, W.E.6
Miller, W.L.7
Auchus, R.J.8
-
64
-
-
62149148156
-
Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
-
Goessling W., North T.E., Loewer S., Lord A.M., Lee S., Stoick-Cooper C.L., Weidinger G., Puder M., Daley G.Q., Moon R.T., Zon L.I. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 2009, 136:1136-1147.
-
(2009)
Cell
, vol.136
, pp. 1136-1147
-
-
Goessling, W.1
North, T.E.2
Loewer, S.3
Lord, A.M.4
Lee, S.5
Stoick-Cooper, C.L.6
Weidinger, G.7
Puder, M.8
Daley, G.Q.9
Moon, R.T.10
Zon, L.I.11
-
65
-
-
79955508675
-
Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations
-
Grachtchouk M., Pero J., Yang S.H., Ermilov A.N., Michael L.E., Wang A., Wilbert D., Patel R.M., Ferris J., Diener J., Allen M., Lim S., Syu L.J., Verhaegen M., Dlugosz A.A. Basal cell carcinomas in mice arise from hair follicle stem cells and multiple epithelial progenitor populations. J. Clin. Invest. 2011, 121:1768-1781.
-
(2011)
J. Clin. Invest.
, vol.121
, pp. 1768-1781
-
-
Grachtchouk, M.1
Pero, J.2
Yang, S.H.3
Ermilov, A.N.4
Michael, L.E.5
Wang, A.6
Wilbert, D.7
Patel, R.M.8
Ferris, J.9
Diener, J.10
Allen, M.11
Lim, S.12
Syu, L.J.13
Verhaegen, M.14
Dlugosz, A.A.15
-
66
-
-
39149133729
-
In vitro functional studies of naturally occurring pathogenic PRKAR1A mutations that are not subject to nonsense mRNA decay
-
Greene E.L., Horvath A.D., Nesterova M., Giatzakis C., Bossis I., Stratakis C.A. In vitro functional studies of naturally occurring pathogenic PRKAR1A mutations that are not subject to nonsense mRNA decay. Hum. Mut. 2008, 29:633-639.
-
(2008)
Hum. Mut.
, vol.29
, pp. 633-639
-
-
Greene, E.L.1
Horvath, A.D.2
Nesterova, M.3
Giatzakis, C.4
Bossis, I.5
Stratakis, C.A.6
-
67
-
-
10844257526
-
Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors
-
Griffin K.J., Kirschner L.S., Matyakhina L., Stergiopoulos S., Robinson-White A., Lenherr S., Weinberg F.D., Claflin E., Meoli E., Cho-Chung Y.S., Stratakis C.A. Down-regulation of regulatory subunit type 1A of protein kinase A leads to endocrine and other tumors. Cancer Res. 2004, 64:8811-8815.
-
(2004)
Cancer Res.
, vol.64
, pp. 8811-8815
-
-
Griffin, K.J.1
Kirschner, L.S.2
Matyakhina, L.3
Stergiopoulos, S.4
Robinson-White, A.5
Lenherr, S.6
Weinberg, F.D.7
Claflin, E.8
Meoli, E.9
Cho-Chung, Y.S.10
Stratakis, C.A.11
-
68
-
-
19944408615
-
A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A-induced lesions
-
Griffin K.J., Kirschner L.S., Matyakhina L., Stergiopoulos S.G., Robinson-White A., Lenherr S.M., Weinberg F.D., Claflin E.S., Batista D., Bourdeau I., Voutetakis A., Sandrini F., Meoli E.M., Bauer A.J., Cho-Chung Y.S., Bornstein S.R., Carney J.A., Stratakis C.A. A transgenic mouse bearing an antisense construct of regulatory subunit type 1A of protein kinase A develops endocrine and other tumours: comparison with Carney complex and other PRKAR1A-induced lesions. J. Med. Genet. 2004, 41:923-931.
-
(2004)
J. Med. Genet.
, vol.41
, pp. 923-931
-
-
Griffin, K.J.1
Kirschner, L.S.2
Matyakhina, L.3
Stergiopoulos, S.G.4
Robinson-White, A.5
Lenherr, S.M.6
Weinberg, F.D.7
Claflin, E.S.8
Batista, D.9
Bourdeau, I.10
Voutetakis, A.11
Sandrini, F.12
Meoli, E.M.13
Bauer, A.J.14
Cho-Chung, Y.S.15
Bornstein, S.R.16
Carney, J.A.17
Stratakis, C.A.18
-
69
-
-
0035650943
-
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib
-
Grösch S., Tegeder I., Niederberger E., Bräutigam L., Geisslinger G. COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. FASEB J. 2001, 15:2742-2744.
-
(2001)
FASEB J.
, vol.15
, pp. 2742-2744
-
-
Grösch, S.1
Tegeder, I.2
Niederberger, E.3
Bräutigam, L.4
Geisslinger, G.5
-
70
-
-
0036736814
-
Mutations of the PRKAR1A gene in Cushing's syndrome due to sporadic primary pigmented nodular adrenocortical disease
-
Groussin L., Jullian E., Perlemoine K., Louvel A., Leheup B., Luton J.P., Bertagna X., Bertherat J. Mutations of the PRKAR1A gene in Cushing's syndrome due to sporadic primary pigmented nodular adrenocortical disease. J. Clin. Endocrinol. Metab. 2002, 87:4324-4329.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 4324-4329
-
-
Groussin, L.1
Jullian, E.2
Perlemoine, K.3
Louvel, A.4
Leheup, B.5
Luton, J.P.6
Bertagna, X.7
Bertherat, J.8
-
71
-
-
0036907704
-
Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology: augmented PKA signaling is associated with adrenal tumorigenesis in PPNAD
-
Groussin L., Kirschner L.S., Vincent-Dejean C., Perlemoine K., Jullian E., Delemer B., Zacharieva S., Pignatelli D., Carney J.A., Luton J.P., Bertagna X., Stratakis C.A., Bertherat J. Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology: augmented PKA signaling is associated with adrenal tumorigenesis in PPNAD. Am. J. Hum. Genet. 2002, 71:1433-1442.
-
(2002)
Am. J. Hum. Genet.
, vol.71
, pp. 1433-1442
-
-
Groussin, L.1
Kirschner, L.S.2
Vincent-Dejean, C.3
Perlemoine, K.4
Jullian, E.5
Delemer, B.6
Zacharieva, S.7
Pignatelli, D.8
Carney, J.A.9
Luton, J.P.10
Bertagna, X.11
Stratakis, C.A.12
Bertherat, J.13
-
72
-
-
33646427720
-
A PRKAR1A mutation associated with primary pigmented nodular adrenocortical disease in 12 kindreds
-
Groussin L., Horvath A., Jullian E., Boikos S., Rene-Corail F., Lefebvre H., Cephise-Velayoudom F.L., Vantyghem M.C., Chanson P., Conte-Devolx B., Lucas M., Gentil A., Malchoff C.D., Tissier F., Carney J.A., Bertagna X., Stratakis C.A., Bertherat J. A PRKAR1A mutation associated with primary pigmented nodular adrenocortical disease in 12 kindreds. J. Clin. Endocrinol. Metab. 2006, 91:1943-1949.
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, pp. 1943-1949
-
-
Groussin, L.1
Horvath, A.2
Jullian, E.3
Boikos, S.4
Rene-Corail, F.5
Lefebvre, H.6
Cephise-Velayoudom, F.L.7
Vantyghem, M.C.8
Chanson, P.9
Conte-Devolx, B.10
Lucas, M.11
Gentil, A.12
Malchoff, C.D.13
Tissier, F.14
Carney, J.A.15
Bertagna, X.16
Stratakis, C.A.17
Bertherat, J.18
-
73
-
-
3242663165
-
Cyclical Cushing syndrome presenting in infancy: an early form of primary pigmented nodular adrenocortical disease, or a new entity?
-
Gunther D.F., Bourdeau I., Matyakhina L., Cassarino D., Kleiner D.E., Griffin K., Courkoutsakis N., Abu-Asab M., Tsokos M., Keil M., Carney J.A., Stratakis C.A. Cyclical Cushing syndrome presenting in infancy: an early form of primary pigmented nodular adrenocortical disease, or a new entity?. J. Clin. Endocrinol. Metab. 2004, 89:3173-3182.
-
(2004)
J. Clin. Endocrinol. Metab.
, vol.89
, pp. 3173-3182
-
-
Gunther, D.F.1
Bourdeau, I.2
Matyakhina, L.3
Cassarino, D.4
Kleiner, D.E.5
Griffin, K.6
Courkoutsakis, N.7
Abu-Asab, M.8
Tsokos, M.9
Keil, M.10
Carney, J.A.11
Stratakis, C.A.12
-
74
-
-
78650868311
-
Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer
-
Faucz F.R., Horvath A., Rothenbuhler A., Almeida M.Q., Libé R., Raffin-Sanson M.L., Bertherat J., Carraro D.M., Soares F.A., de Campos Molina G., Campos A.H., Alexandre R.B., Bendhack M.L., Nesterova M., Stratakis C.A. Phosphodiesterase 11A (PDE11A) genetic variants may increase susceptibility to prostatic cancer. J. Clin. Endocrinol. Metab. 2011, 96:E135-E140.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Faucz, F.R.1
Horvath, A.2
Rothenbuhler, A.3
Almeida, M.Q.4
Libé, R.5
Raffin-Sanson, M.L.6
Bertherat, J.7
Carraro, D.M.8
Soares, F.A.9
de Campos Molina, G.10
Campos, A.H.11
Alexandre, R.B.12
Bendhack, M.L.13
Nesterova, M.14
Stratakis, C.A.15
-
75
-
-
0038030796
-
Cushing's syndrome secondary to adrenocorticotropin-independent macronodular adrenocortical hyperplasia due to activating mutations of GNAS1 gene
-
Fragoso M.C., Domenice S., Latronico A.C., Martin R.M., Pereira M.A., Zerbini M.C., Lucon A.M., Mendonca B.B. Cushing's syndrome secondary to adrenocorticotropin-independent macronodular adrenocortical hyperplasia due to activating mutations of GNAS1 gene. J. Clin. Endocrinol. Metab. 2003, 88:2147-2151.
-
(2003)
J. Clin. Endocrinol. Metab.
, vol.88
, pp. 2147-2151
-
-
Fragoso, M.C.1
Domenice, S.2
Latronico, A.C.3
Martin, R.M.4
Pereira, M.A.5
Zerbini, M.C.6
Lucon, A.M.7
Mendonca, B.B.8
-
76
-
-
33846219617
-
Arthropathy of neonatal onset multisystem inflammatory disease (NOMID/CINCA)
-
Hill S.C., Namde M., Dwyer A., Poznanski A., Canna S., Goldbach-Mansky S. Arthropathy of neonatal onset multisystem inflammatory disease (NOMID/CINCA). Pediatr. Radiol. 2007, 37:145-152.
-
(2007)
Pediatr. Radiol.
, vol.37
, pp. 145-152
-
-
Hill, S.C.1
Namde, M.2
Dwyer, A.3
Poznanski, A.4
Canna, S.5
Goldbach-Mansky, S.6
-
77
-
-
33745548423
-
A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia
-
Horvath A., Boikos S., Giatzakis C., Robinson-White A., Groussin L., Griffin K.J., Stein E., Levine E., Delimpasi G., Hsiao H.P., Keil M., Heyerdahl S., Matyakhina L., Libè R., Fratticci A., Kirschner L.S., Cramer K., Gaillard R.C., Bertagna X., Carney J.A., Bertherat J., Bossis I., Stratakis C.A. A genome-wide scan identifies mutations in the gene encoding phosphodiesterase 11A4 (PDE11A) in individuals with adrenocortical hyperplasia. Nat. Genet. 2006, 38:794-800.
-
(2006)
Nat. Genet.
, vol.38
, pp. 794-800
-
-
Horvath, A.1
Boikos, S.2
Giatzakis, C.3
Robinson-White, A.4
Groussin, L.5
Griffin, K.J.6
Stein, E.7
Levine, E.8
Delimpasi, G.9
Hsiao, H.P.10
Keil, M.11
Heyerdahl, S.12
Matyakhina, L.13
Libè, R.14
Fratticci, A.15
Kirschner, L.S.16
Cramer, K.17
Gaillard, R.C.18
Bertagna, X.19
Carney, J.A.20
Bertherat, J.21
Bossis, I.22
Stratakis, C.A.23
more..
-
78
-
-
33846242137
-
Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population
-
Horvath A., Giatzakis C., Robinson-White A., Boikos S., Levine E., Griffin K., Stein E., Kamvissi V., Soni P., Bossis I., de Herder W., Carney J.A., Bertherat J., Gregersen P.K., Remmers E.F., Stratakis C.A. Adrenal hyperplasia and adenomas are associated with inhibition of phosphodiesterase 11A in carriers of PDE11A sequence variants that are frequent in the population. Cancer Res. 2006, 66:11571-11575.
-
(2006)
Cancer Res.
, vol.66
, pp. 11571-11575
-
-
Horvath, A.1
Giatzakis, C.2
Robinson-White, A.3
Boikos, S.4
Levine, E.5
Griffin, K.6
Stein, E.7
Kamvissi, V.8
Soni, P.9
Bossis, I.10
de Herder, W.11
Carney, J.A.12
Bertherat, J.13
Gregersen, P.K.14
Remmers, E.F.15
Stratakis, C.A.16
-
79
-
-
39049101528
-
Mutation in PDE8B, a cAMP-specific phosphodiesterase in adrenal hyperplasia
-
Horvath A., Mericq V., Stratakis C.A. Mutation in PDE8B, a cAMP-specific phosphodiesterase in adrenal hyperplasia. N. Engl. J. Med. 2008, 358:750-752.
-
(2008)
N. Engl. J. Med.
, vol.358
, pp. 750-752
-
-
Horvath, A.1
Mericq, V.2
Stratakis, C.A.3
-
80
-
-
53249142160
-
A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex
-
Horvath A., Giatzakis C., Tsang K., Greene E., Osorio P., Boikos S., Libè R., Patronas Y., Robinson-White A., Remmers E., Bertherat J., Nesterova M., Stratakis C.A. A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex. Eur. J. Hum. Genet. 2008, 16:1245-1253.
-
(2008)
Eur. J. Hum. Genet.
, vol.16
, pp. 1245-1253
-
-
Horvath, A.1
Giatzakis, C.2
Tsang, K.3
Greene, E.4
Osorio, P.5
Boikos, S.6
Libè, R.7
Patronas, Y.8
Robinson-White, A.9
Remmers, E.10
Bertherat, J.11
Nesterova, M.12
Stratakis, C.A.13
-
81
-
-
38949096090
-
Large deletions of the PRKAR1A gene in Carney complex: phenotype correlations and implications for laboratory and diagnostic testing
-
Horvath A., Bossis I., Giatzakis C., Levine E., Weinberg F., Meoli E., Siegel J., Soni P., Groussin L., Matyakhina L., Verma S., Carney J.A., Bertherat J., Stratakis C.A. Large deletions of the PRKAR1A gene in Carney complex: phenotype correlations and implications for laboratory and diagnostic testing. Clin. Cancer Res. 2008, 14:388-395.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 388-395
-
-
Horvath, A.1
Bossis, I.2
Giatzakis, C.3
Levine, E.4
Weinberg, F.5
Meoli, E.6
Siegel, J.7
Soni, P.8
Groussin, L.9
Matyakhina, L.10
Verma, S.11
Carney, J.A.12
Bertherat, J.13
Stratakis, C.A.14
-
82
-
-
67650505040
-
Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors
-
Horvath A., Korde L., Greene M.H., Libe R., Osorio P., Faucz F.R., Raffin-Sanson M.L., Tsang K.M., Drori-Herishanu L., Patronas Y., Remmers E.F., Nikita M.E., Moran J., Greene J., Nesterova M., Merino M., Bertherat J., Stratakis C.A. Functional phosphodiesterase 11A mutations may modify the risk of familial and bilateral testicular germ cell tumors. Cancer Res. 2009, 69:5301-5306.
-
(2009)
Cancer Res.
, vol.69
, pp. 5301-5306
-
-
Horvath, A.1
Korde, L.2
Greene, M.H.3
Libe, R.4
Osorio, P.5
Faucz, F.R.6
Raffin-Sanson, M.L.7
Tsang, K.M.8
Drori-Herishanu, L.9
Patronas, Y.10
Remmers, E.F.11
Nikita, M.E.12
Moran, J.13
Greene, J.14
Nesterova, M.15
Merino, M.16
Bertherat, J.17
Stratakis, C.A.18
-
83
-
-
77950427180
-
Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update
-
Horvath A., Bertherat J., Groussin L., Guillaud-Bataille M., Tsang K., Cazabat L., Libé R., Remmers E., René-Corail F., Faucz F.R., Clauser E., Calender A., Bertagna X., Carney J.A., Stratakis C.A. Mutations and polymorphisms in the gene encoding regulatory subunit type 1-alpha of protein kinase A (PRKAR1A): an update. Hum. Mutat. 2010, 31:369-379.
-
(2010)
Hum. Mutat.
, vol.31
, pp. 369-379
-
-
Horvath, A.1
Bertherat, J.2
Groussin, L.3
Guillaud-Bataille, M.4
Tsang, K.5
Cazabat, L.6
Libé, R.7
Remmers, E.8
René-Corail, F.9
Faucz, F.R.10
Clauser, E.11
Calender, A.12
Bertagna, X.13
Carney, J.A.14
Stratakis, C.A.15
-
84
-
-
77952389559
-
Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels
-
Horvath A., Faucz F., Finkielstain G.P., Nikita M.E., Rothenbuhler A., Almeida M., Mericq V., Stratakis C.A. Haplotype analysis of the promoter region of phosphodiesterase type 8B (PDE8B) in correlation with inactivating PDE8B mutation and the serum thyroid-stimulating hormone levels. Thyroid 2010, 20:363-367.
-
(2010)
Thyroid
, vol.20
, pp. 363-367
-
-
Horvath, A.1
Faucz, F.2
Finkielstain, G.P.3
Nikita, M.E.4
Rothenbuhler, A.5
Almeida, M.6
Mericq, V.7
Stratakis, C.A.8
-
85
-
-
0036351299
-
Molecular and behavioral effects of a null mutation in all PKA C beta isoforms
-
Howe D.G., Wiley J.C., McKnight G.S. Molecular and behavioral effects of a null mutation in all PKA C beta isoforms. Mol. Cell. Neurosci. 2002, 20:515-524.
-
(2002)
Mol. Cell. Neurosci.
, vol.20
, pp. 515-524
-
-
Howe, D.G.1
Wiley, J.C.2
McKnight, G.S.3
-
86
-
-
68549109424
-
Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in adrenocorticotropin-independent macronodular adrenal hyperplasia compared with other adrenocortical tumors
-
Hsiao H.P., Kirschner L.S., Bourdeau I., Keil M.F., Boikos S.A., Verma S., Robinson-White A.J., Nesterova M., Lacroix A., Stratakis C.A. Clinical and genetic heterogeneity, overlap with other tumor syndromes, and atypical glucocorticoid hormone secretion in adrenocorticotropin-independent macronodular adrenal hyperplasia compared with other adrenocortical tumors. J. Clin. Endocrinol. Metab. 2009, 94:2930-2937.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 2930-2937
-
-
Hsiao, H.P.1
Kirschner, L.S.2
Bourdeau, I.3
Keil, M.F.4
Boikos, S.A.5
Verma, S.6
Robinson-White, A.J.7
Nesterova, M.8
Lacroix, A.9
Stratakis, C.A.10
-
87
-
-
65949092330
-
MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling
-
Iliopoulos D., Bimpaki E.I., Nesterova M., Stratakis C.A. MicroRNA signature of primary pigmented nodular adrenocortical disease: clinical correlations and regulation of Wnt signaling. Cancer Res. 2009, 69:3278-3282.
-
(2009)
Cancer Res.
, vol.69
, pp. 3278-3282
-
-
Iliopoulos, D.1
Bimpaki, E.I.2
Nesterova, M.3
Stratakis, C.A.4
-
88
-
-
78651082042
-
Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations
-
NIH Pediatric and Wild-Type GIST Clinic
-
Janeway K.A., Kim S.Y., Lodish M., Nosé V., Rustin P., Gaal J., Dahia P.L., Liegl B., Ball E.R., Raygada M., Lai A.H., Kelly L., Hornick J.L., NIH Pediatric and Wild-Type GIST Clinic, O'Sullivan M., de Krijger R.R., Dinjens W.N., Demetri G.D., Antonescu C.R., Fletcher J.A., Helman L., Stratakis C.A. Defects in succinate dehydrogenase in gastrointestinal stromal tumors lacking KIT and PDGFRA mutations. Proc. Natl. Acad. Sci. USA 2011, 108:314-318.
-
(2011)
Proc. Natl. Acad. Sci. USA
, vol.108
, pp. 314-318
-
-
Janeway, K.A.1
Kim, S.Y.2
Lodish, M.3
Nosé, V.4
Rustin, P.5
Gaal, J.6
Dahia, P.L.7
Liegl, B.8
Ball, E.R.9
Raygada, M.10
Lai, A.H.11
Kelly, L.12
Hornick, J.L.13
O'Sullivan, M.14
de Krijger, R.R.15
Dinjens, W.N.16
Demetri, G.D.17
Antonescu, C.R.18
Fletcher, J.A.19
Helman, L.20
Stratakis, C.A.21
more..
-
89
-
-
77956597311
-
Mouse models of endocrine tumours
-
Jones G.N., Manchanda P.K., Pringle D.R., Zhang M., Kirschner L.S. Mouse models of endocrine tumours. Best Pract. Res. Clin. Endocrinol. Metab. 2010, 24:451-460.
-
(2010)
Best Pract. Res. Clin. Endocrinol. Metab.
, vol.24
, pp. 451-460
-
-
Jones, G.N.1
Manchanda, P.K.2
Pringle, D.R.3
Zhang, M.4
Kirschner, L.S.5
-
90
-
-
77955001407
-
Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification
-
Jones G.N., Pringle D.R., Yin Z., Carlton M.M., Powell K.A., Weinstein M.B., Toribio R.E., La Perle K.M., Kirschner L.S. Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification. Mol. Endocrinol. 2010, 24:1559-1568.
-
(2010)
Mol. Endocrinol.
, vol.24
, pp. 1559-1568
-
-
Jones, G.N.1
Pringle, D.R.2
Yin, Z.3
Carlton, M.M.4
Powell, K.A.5
Weinstein, M.B.6
Toribio, R.E.7
La Perle, K.M.8
Kirschner, L.S.9
-
91
-
-
80052545178
-
Functional imaging of SDHx-related head and neck paragangliomas: comparison of 18F-fluorodihydroxyphenylalanine, 18F-fluorodopamine, 18F-fluoro-2-deoxy-D-glucose PET, 123I-metaiodobenzylguanidine scintigraphy, and 111In-pentetreotide scintigraphy
-
King K.S., Chen C.C., Alexopoulos D.K., Whatley M.A., Reynolds J.C., Patronas N., Ling A., Adams K.T., Xekouki P., Lando H., Stratakis C.A., Pacak K. Functional imaging of SDHx-related head and neck paragangliomas: comparison of 18F-fluorodihydroxyphenylalanine, 18F-fluorodopamine, 18F-fluoro-2-deoxy-D-glucose PET, 123I-metaiodobenzylguanidine scintigraphy, and 111In-pentetreotide scintigraphy. J. Clin. Endocrinol. Metab. 2011, 96:2779-2785.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
, pp. 2779-2785
-
-
King, K.S.1
Chen, C.C.2
Alexopoulos, D.K.3
Whatley, M.A.4
Reynolds, J.C.5
Patronas, N.6
Ling, A.7
Adams, K.T.8
Xekouki, P.9
Lando, H.10
Stratakis, C.A.11
Pacak, K.12
-
92
-
-
80755127100
-
Metastatic pheochromocytoma/paraganglioma related to primary tumor development in childhood or adolescence. significant link to SDHB mutations
-
King K.S., Prodanov T., Kantorovich V., Fojo T., Hewitt J.K., Zacharin M., Wesley R., Lodish M., Raygada M., Gimenez-Roqueplo A.P., McCormack S., Eisenhofer G., Milosevic D., Kebebew E., Stratakis C.A., Pacak K. Metastatic pheochromocytoma/paraganglioma related to primary tumor development in childhood or adolescence. significant link to SDHB mutations. J. Clin. Oncol. 2011, 29:4137-4142.
-
(2011)
J. Clin. Oncol.
, vol.29
, pp. 4137-4142
-
-
King, K.S.1
Prodanov, T.2
Kantorovich, V.3
Fojo, T.4
Hewitt, J.K.5
Zacharin, M.6
Wesley, R.7
Lodish, M.8
Raygada, M.9
Gimenez-Roqueplo, A.P.10
McCormack, S.11
Eisenhofer, G.12
Milosevic, D.13
Kebebew, E.14
Stratakis, C.A.15
Pacak, K.16
-
93
-
-
0033812849
-
Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex
-
Kirschner L.S., Carney J.A., Pack S.D., Taymans S.E., Giatzakis C., Cho Y.S., Cho-Chung Y.S., Stratakis C.A. Mutations of the gene encoding the protein kinase A type I-alpha regulatory subunit in patients with the Carney complex. Nat. Genet. 2000, 26:89-92.
-
(2000)
Nat. Genet.
, vol.26
, pp. 89-92
-
-
Kirschner, L.S.1
Carney, J.A.2
Pack, S.D.3
Taymans, S.E.4
Giatzakis, C.5
Cho, Y.S.6
Cho-Chung, Y.S.7
Stratakis, C.A.8
-
94
-
-
0034642302
-
Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex
-
Kirschner L.S., Sandrini F., Monbo J., Lin J.P., Carney J.A., Stratakis C.A. Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex. Hum. Mol. Genet. 2000, 9:3037-3046.
-
(2000)
Hum. Mol. Genet.
, vol.9
, pp. 3037-3046
-
-
Kirschner, L.S.1
Sandrini, F.2
Monbo, J.3
Lin, J.P.4
Carney, J.A.5
Stratakis, C.A.6
-
95
-
-
19644364776
-
A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues
-
Kirschner L.S., Kusewitt D.F., Matyakhina L., Towns W.H., Carney J.A., Westphal H., Stratakis C.A. A mouse model for the Carney complex tumor syndrome develops neoplasia in cyclic AMP-responsive tissues. Cancer Res. 2005, 65:4506-4514.
-
(2005)
Cancer Res.
, vol.65
, pp. 4506-4514
-
-
Kirschner, L.S.1
Kusewitt, D.F.2
Matyakhina, L.3
Towns, W.H.4
Carney, J.A.5
Westphal, H.6
Stratakis, C.A.7
-
96
-
-
42549164807
-
Wnt signalling and its impact on development and cancer
-
Klaus A., Birchmeier W. Wnt signalling and its impact on development and cancer. Nat. Rev. Cancer 2008, 8:387-398.
-
(2008)
Nat. Rev. Cancer
, vol.8
, pp. 387-398
-
-
Klaus, A.1
Birchmeier, W.2
-
97
-
-
42649118106
-
Human mesenchymal stem cell proliferation is regulated by PGE2 through differential activation of cAMP-dependent protein kinase isoforms
-
Kleiveland C.R., Kassem M., Lea T. Human mesenchymal stem cell proliferation is regulated by PGE2 through differential activation of cAMP-dependent protein kinase isoforms. Exp. Cell Res. 2008, 314:1831-1838.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 1831-1838
-
-
Kleiveland, C.R.1
Kassem, M.2
Lea, T.3
-
98
-
-
84858258974
-
Standardized LC-MS/MS based steroid hormone profile-analysis
-
Koal T., Schmiederer D., Pham-Tuan H., Röhring C., Rauh M. Standardized LC-MS/MS based steroid hormone profile-analysis. J. Steroid Biochem. Mol. Biol. 2011, 129:129-138.
-
(2011)
J. Steroid Biochem. Mol. Biol.
, vol.129
, pp. 129-138
-
-
Koal, T.1
Schmiederer, D.2
Pham-Tuan, H.3
Röhring, C.4
Rauh, M.5
-
99
-
-
0033728248
-
A novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22)
-
Lafferty A.R., Torpy D.J., Stowasser M., Taymans S.E., Lin J.P., Huggard P., Gordon R.D., Stratakis C.A. A novel genetic locus for low renin hypertension: familial hyperaldosteronism type II maps to chromosome 7 (7p22). J. Med. Genet. 2000, 37:831-835.
-
(2000)
J. Med. Genet.
, vol.37
, pp. 831-835
-
-
Lafferty, A.R.1
Torpy, D.J.2
Stowasser, M.3
Taymans, S.E.4
Lin, J.P.5
Huggard, P.6
Gordon, R.D.7
Stratakis, C.A.8
-
100
-
-
33745234207
-
Increased risk of cancer in patients with fumarate hydratase germline mutation
-
Lehtonen H.J., Kiuru M., Ylisaukko-Oja S.K., Salovaara R., Herva R., Koivisto P.A., Vierimaa O., Aittomäki K., Pukkala E., Launonen V., Aaltonen L.A. Increased risk of cancer in patients with fumarate hydratase germline mutation. J. Med. Genet. 2006, 43:523-526.
-
(2006)
J. Med. Genet.
, vol.43
, pp. 523-526
-
-
Lehtonen, H.J.1
Kiuru, M.2
Ylisaukko-Oja, S.K.3
Salovaara, R.4
Herva, R.5
Koivisto, P.A.6
Vierimaa, O.7
Aittomäki, K.8
Pukkala, E.9
Launonen, V.10
Aaltonen, L.A.11
-
101
-
-
82255192267
-
Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment
-
Levy I., Horvath A., Azevedo M., de Alexandre R.B., Stratakis C.A. Phosphodiesterase function and endocrine cells: links to human disease and roles in tumor development and treatment. Curr. Opin. Pharmacol. 2011, 11:689-697.
-
(2011)
Curr. Opin. Pharmacol.
, vol.11
, pp. 689-697
-
-
Levy, I.1
Horvath, A.2
Azevedo, M.3
de Alexandre, R.B.4
Stratakis, C.A.5
-
102
-
-
22944472450
-
Profiles of PrKX expression in developmental mouse embryo and human tissues
-
Li W., Yu Z.X., Kotin R.M. Profiles of PrKX expression in developmental mouse embryo and human tissues. J. Histochem. Cytochem. 2005, 53:1003-1009.
-
(2005)
J. Histochem. Cytochem.
, vol.53
, pp. 1003-1009
-
-
Li, W.1
Yu, Z.X.2
Kotin, R.M.3
-
103
-
-
52449114622
-
Phosphodiesterase 11A4 (PDE11A4) and genetic predisposition to adrenocortical tumors
-
Libe R., Fratticci A., Coste J., Tissier F., Horvath A., Groussin L., Rene-Corail F., Bertagna X., Raffin-Sanson M.L., Stratakis C.A., Bertherat J. Phosphodiesterase 11A4 (PDE11A4) and genetic predisposition to adrenocortical tumors. Clin. Cancer Res. 2008, 14:4016-4024.
-
(2008)
Clin. Cancer Res.
, vol.14
, pp. 4016-4024
-
-
Libe, R.1
Fratticci, A.2
Coste, J.3
Tissier, F.4
Horvath, A.5
Groussin, L.6
Rene-Corail, F.7
Bertagna, X.8
Raffin-Sanson, M.L.9
Stratakis, C.A.10
Bertherat, J.11
-
104
-
-
78650898282
-
Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype
-
Libé R., Horvath A., Vezzosi D., Fratticci A., Coste J., Perlemoine K., Ragazzon B., Guillaud-Bataille M., Groussin L., Clauser E., Raffin-Sanson M.L., Siegel J., Moran J., Drori-Herishanu L., Faucz F.R., Lodish M., Nesterova M., Bertagna X., Bertherat J., Stratakis C.A. Frequent phosphodiesterase 11A gene (PDE11A) defects in patients with Carney complex (CNC) caused by PRKAR1A mutations: PDE11A may contribute to adrenal and testicular tumors in CNC as a modifier of the phenotype. J. Clin. Endocrinol. Metab. 2011, 96:E208-E214.
-
(2011)
J. Clin. Endocrinol. Metab.
, vol.96
-
-
Libé, R.1
Horvath, A.2
Vezzosi, D.3
Fratticci, A.4
Coste, J.5
Perlemoine, K.6
Ragazzon, B.7
Guillaud-Bataille, M.8
Groussin, L.9
Clauser, E.10
Raffin-Sanson, M.L.11
Siegel, J.12
Moran, J.13
Drori-Herishanu, L.14
Faucz, F.R.15
Lodish, M.16
Nesterova, M.17
Bertagna, X.18
Bertherat, J.19
Stratakis, C.A.20
more..
-
105
-
-
79958182720
-
Recurrent PRKAR1A mutation in acrodysostosis with hormone resistance
-
Linglart A., Menguy C., Couvineau A., Auzan C., Gunes Y., Cancel M., Motte E., Pinto G., Chanson P., Bougnères P., Clauser E., Silve C. Recurrent PRKAR1A mutation in acrodysostosis with hormone resistance. N. Engl. J. Med. 2011, 364:2218-2226.
-
(2011)
N. Engl. J. Med.
, vol.364
, pp. 2218-2226
-
-
Linglart, A.1
Menguy, C.2
Couvineau, A.3
Auzan, C.4
Gunes, Y.5
Cancel, M.6
Motte, E.7
Pinto, G.8
Chanson, P.9
Bougnères, P.10
Clauser, E.11
Silve, C.12
-
106
-
-
33745728170
-
Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells
-
Liu S., Dontu G., Mantle I.D., Patel S., Ahn N.S., Jackson K.W., Suri P., Wicha M.S. Hedgehog signaling and Bmi-1 regulate self-renewal of normal and malignant human mammary stem cells. Cancer Res. 2006, 66:6063-6071.
-
(2006)
Cancer Res.
, vol.66
, pp. 6063-6071
-
-
Liu, S.1
Dontu, G.2
Mantle, I.D.3
Patel, S.4
Ahn, N.S.5
Jackson, K.W.6
Suri, P.7
Wicha, M.S.8
-
107
-
-
78751522709
-
Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks
-
Liu S., Ginestier C., Ou S.J., Clouthier S.G., Patel S.H., Monville F., Korkaya H., Heath A., Dutcher J., Kleer C.G., Jung Y., Dontu G., Taichman R., Wicha M.S. Breast cancer stem cells are regulated by mesenchymal stem cells through cytokine networks. Cancer Res. 2011, 71:614-624.
-
(2011)
Cancer Res.
, vol.71
, pp. 614-624
-
-
Liu, S.1
Ginestier, C.2
Ou, S.J.3
Clouthier, S.G.4
Patel, S.H.5
Monville, F.6
Korkaya, H.7
Heath, A.8
Dutcher, J.9
Kleer, C.G.10
Jung, Y.11
Dontu, G.12
Taichman, R.13
Wicha, M.S.14
-
108
-
-
77956199558
-
Succinate dehydrogenase gene mutations are strongly associated with paraganglioma of the organ of Zuckerkandl
-
Lodish M.B., Adams K., Huynh T., Prodanov T., Ling A., Chen C., Shusterman S., Jimenez C., Merino M., Hughes M., Cradic K., Singh R., Milosevic D., Stratakis C.A., Pacak K. Succinate dehydrogenase gene mutations are strongly associated with paraganglioma of the organ of Zuckerkandl. Endocr. Relat. Cancer 2010, 17:581-588.
-
(2010)
Endocr. Relat. Cancer
, vol.17
, pp. 581-588
-
-
Lodish, M.B.1
Adams, K.2
Huynh, T.3
Prodanov, T.4
Ling, A.5
Chen, C.6
Shusterman, S.7
Jimenez, C.8
Merino, M.9
Hughes, M.10
Cradic, K.11
Singh, R.12
Milosevic, D.13
Stratakis, C.A.14
Pacak, K.15
-
109
-
-
67650242193
-
The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits
-
Louiset E., Stratakis C.A., Perraudin V., Griffin K.J., Libé R., Cabrol S., Fève B., Young J., Groussin L., Bertherat J., Lefebvre H. The paradoxical increase in cortisol secretion induced by dexamethasone in primary pigmented nodular adrenocortical disease involves a glucocorticoid receptor-mediated effect of dexamethasone on protein kinase A catalytic subunits. J. Clin. Endocrinol. Metab. 2009, 94:2406-2413.
-
(2009)
J. Clin. Endocrinol. Metab.
, vol.94
, pp. 2406-2413
-
-
Louiset, E.1
Stratakis, C.A.2
Perraudin, V.3
Griffin, K.J.4
Libé, R.5
Cabrol, S.6
Fève, B.7
Young, J.8
Groussin, L.9
Bertherat, J.10
Lefebvre, H.11
-
110
-
-
36549062074
-
Different expression of protein kinase A (PKA) regulatory subunits in cortisol-secreting adrenocortical tumors: relationship with cell proliferation
-
Mantovani G., Lania A.G., Bondioni S., Peverelli E., Pedroni C., Ferrero S., Pellegrini C., Vicentini L., Arnaldi G., Bosari S., Beck-Peccoz P., Spada A. Different expression of protein kinase A (PKA) regulatory subunits in cortisol-secreting adrenocortical tumors: relationship with cell proliferation. Exp. Cell Res. 2008, 314:123-130.
-
(2008)
Exp. Cell Res.
, vol.314
, pp. 123-130
-
-
Mantovani, G.1
Lania, A.G.2
Bondioni, S.3
Peverelli, E.4
Pedroni, C.5
Ferrero, S.6
Pellegrini, C.7
Vicentini, L.8
Arnaldi, G.9
Bosari, S.10
Beck-Peccoz, P.11
Spada, A.12
-
111
-
-
23444442691
-
Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells
-
Maier T.J., Janssen A., Schmidt R., Geisslinger G., Grösch S. Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. FASEB J. 2005, 19:1353-2355.
-
(2005)
FASEB J.
, vol.19
, pp. 1353-2355
-
-
Maier, T.J.1
Janssen, A.2
Schmidt, R.3
Geisslinger, G.4
Grösch, S.5
-
112
-
-
34548610383
-
Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells
-
Martin B.R., Deerinck T.J., Ellisman M.H., Taylor S.S., Tsien R.Y. Isoform-specific PKA dynamics revealed by dye-triggered aggregation and DAKAP1alpha-mediated localization in living cells. Chem. Biol. 2007, 14:1031-1042.
-
(2007)
Chem. Biol.
, vol.14
, pp. 1031-1042
-
-
Martin, B.R.1
Deerinck, T.J.2
Ellisman, M.H.3
Taylor, S.S.4
Tsien, R.Y.5
-
113
-
-
77956181765
-
Consequences of adrenal venous sampling in primary hyperaldosteronism and predictors of unilateral adrenal disease
-
Mathur A., Kemp C.D., Dutta U., Baid S., Ayala A., Chang R.E., Steinberg S.M., Papademetriou V., Lange E., Libutti S.K., Pingpank J.F., Alexander H.R., Phan G.Q., Hughe M., Linehan W.M., Pinto P.A., Stratakis C.A., Kebebew E. Consequences of adrenal venous sampling in primary hyperaldosteronism and predictors of unilateral adrenal disease. J. Am. Coll. Surg. 2010, 211:384-390.
-
(2010)
J. Am. Coll. Surg.
, vol.211
, pp. 384-390
-
-
Mathur, A.1
Kemp, C.D.2
Dutta, U.3
Baid, S.4
Ayala, A.5
Chang, R.E.6
Steinberg, S.M.7
Papademetriou, V.8
Lange, E.9
Libutti, S.K.10
Pingpank, J.F.11
Alexander, H.R.12
Phan, G.Q.13
Hughe, M.14
Linehan, W.M.15
Pinto, P.A.16
Stratakis, C.A.17
Kebebew, E.18
-
114
-
-
0037389713
-
Chromosome 2 (2p16) abnormalities in Carney complex tumours
-
Matyakhina L., Pack S., Kirschner L.S., Pak E., Mannan P., Jaikumar J., Taymans S.E., Sandrini F., Carney J.A., Stratakis C.A. Chromosome 2 (2p16) abnormalities in Carney complex tumours. J. Med. Genet. 2003, 40:268-277.
-
(2003)
J. Med. Genet.
, vol.40
, pp. 268-277
-
-
Matyakhina, L.1
Pack, S.2
Kirschner, L.S.3
Pak, E.4
Mannan, P.5
Jaikumar, J.6
Taymans, S.E.7
Sandrini, F.8
Carney, J.A.9
Stratakis, C.A.10
-
115
-
-
21244452808
-
Hereditary leiomyomatosis associated with bilateral, massive, macronodular adrenocortical disease and atypical cushing syndrome: a clinical and molecular genetic investigation
-
Matyakhina L., Freedman R.J., Bourdeau I., Wei M.H., Stergiopoulos S.G., Chidakel A., Walther M., Abu-Asab M., Tsokos M., Keil M., Toro J., Linehan W.M., Stratakis C.A. Hereditary leiomyomatosis associated with bilateral, massive, macronodular adrenocortical disease and atypical cushing syndrome: a clinical and molecular genetic investigation. J. Clin. Endocrinol. Metab. 2005, 90:3773-3779.
-
(2005)
J. Clin. Endocrinol. Metab.
, vol.90
, pp. 3773-3779
-
-
Matyakhina, L.1
Freedman, R.J.2
Bourdeau, I.3
Wei, M.H.4
Stergiopoulos, S.G.5
Chidakel, A.6
Walther, M.7
Abu-Asab, M.8
Tsokos, M.9
Keil, M.10
Toro, J.11
Linehan, W.M.12
Stratakis, C.A.13
-
116
-
-
34547781842
-
Genetics of carney triad: recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors
-
Matyakhina L., Bei T.A., McWhinney S.R., Pasini B., Cameron S., Gunawan B., Stergiopoulos S.G., Boikos S., Muchow M., Dutra A., Pak E., Campo E., Cid M.C., Gomez F., Gaillard R.C., Assie G., Füzesi L., Baysal B.E., Eng C., Carney J.A., Stratakis C.A. Genetics of carney triad: recurrent losses at chromosome 1 but lack of germline mutations in genes associated with paragangliomas and gastrointestinal stromal tumors. J. Clin. Endocrinol. Metab. 2007, 92:2938-2943.
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 2938-2943
-
-
Matyakhina, L.1
Bei, T.A.2
McWhinney, S.R.3
Pasini, B.4
Cameron, S.5
Gunawan, B.6
Stergiopoulos, S.G.7
Boikos, S.8
Muchow, M.9
Dutra, A.10
Pak, E.11
Campo, E.12
Cid, M.C.13
Gomez, F.14
Gaillard, R.C.15
Assie, G.16
Füzesi, L.17
Baysal, B.E.18
Eng, C.19
Carney, J.A.20
Stratakis, C.A.21
more..
-
117
-
-
33749000851
-
Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency
-
Mavrakis M., Lippincott-Schwartz J., Stratakis C.A., Bossis I. Depletion of type IA regulatory subunit (RIalpha) of protein kinase A (PKA) in mammalian cells and tissues activates mTOR and causes autophagic deficiency. Hum. Mol. Genet. 2006, 15:2962-2971.
-
(2006)
Hum. Mol. Genet.
, vol.15
, pp. 2962-2971
-
-
Mavrakis, M.1
Lippincott-Schwartz, J.2
Stratakis, C.A.3
Bossis, I.4
-
118
-
-
0031622703
-
Cyclic AMP, PKA, and the physiological regulation of adiposity
-
McKnight G.S., Cummings D.E., Amieux P.S., Sikorski M.A., Brandon E.P., Planas J.V., Motamed K., Idzerda R.L. Cyclic AMP, PKA, and the physiological regulation of adiposity. Recent Prog. Horm. Res. 1998, 53:139-161.
-
(1998)
Recent Prog. Horm. Res.
, vol.53
, pp. 139-161
-
-
McKnight, G.S.1
Cummings, D.E.2
Amieux, P.S.3
Sikorski, M.A.4
Brandon, E.P.5
Planas, J.V.6
Motamed, K.7
Idzerda, R.L.8
-
119
-
-
34548386693
-
International Carney Triad and Carney-Stratakis Syndrome Consortium. Familial gastrointestinal stromal tumors and germ-line mutations
-
McWhinney S.R., Pasini B., Stratakis C.A. International Carney Triad and Carney-Stratakis Syndrome Consortium. Familial gastrointestinal stromal tumors and germ-line mutations. N. Engl. J. Med. 2007, 357:1054-1056.
-
(2007)
N. Engl. J. Med.
, vol.357
, pp. 1054-1056
-
-
McWhinney, S.R.1
Pasini, B.2
Stratakis, C.A.3
-
120
-
-
44849132922
-
Protein kinase A (PKA) effects of an expressed PRKAR1A mutation associated with aggressive tumors
-
Meoli E., Bossis I., Cazabat L., Mavrakis M., Horvath A., Shiferaw M., Fumey G., Perlemoine K., Muchow M., Robinson-White A., Weinberg F., Nesterova M., Patronas Y., Groussin L., Bertherat J., Stratakis C.A. Protein kinase A (PKA) effects of an expressed PRKAR1A mutation associated with aggressive tumors. Cancer Res. 2008, 68:3133-3141.
-
(2008)
Cancer Res.
, vol.68
, pp. 3133-3141
-
-
Meoli, E.1
Bossis, I.2
Cazabat, L.3
Mavrakis, M.4
Horvath, A.5
Shiferaw, M.6
Fumey, G.7
Perlemoine, K.8
Muchow, M.9
Robinson-White, A.10
Weinberg, F.11
Nesterova, M.12
Patronas, Y.13
Groussin, L.14
Bertherat, J.15
Stratakis, C.A.16
-
121
-
-
77956368069
-
Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice
-
Molyneux S.D., Di Grappa M.A., Beristain A.G., McKee T.D., Wai D.H., Paderova J., Kashyap M., Hu P., Maiuri T., Narala S.R., Stambolic V., Squire J., Penninger J., Sanchez O., Triche T.J., Wood G.A., Kirschner L.S., Khokha R. Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice. J. Clin. Invest. 2010, 120:3310-3325.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 3310-3325
-
-
Molyneux, S.D.1
Di Grappa, M.A.2
Beristain, A.G.3
McKee, T.D.4
Wai, D.H.5
Paderova, J.6
Kashyap, M.7
Hu, P.8
Maiuri, T.9
Narala, S.R.10
Stambolic, V.11
Squire, J.12
Penninger, J.13
Sanchez, O.14
Triche, T.J.15
Wood, G.A.16
Kirschner, L.S.17
Khokha, R.18
-
122
-
-
84856770071
-
Carney complex with adrenal cortical carcinoma
-
Morin E., Mete O., Wasserman J.D., Joshua A.M., Asa S.L., Ezzat S. Carney complex with adrenal cortical carcinoma. J. Clin. Endocrinol. Metab. 2012, 97:E202-E206.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Morin, E.1
Mete, O.2
Wasserman, J.D.3
Joshua, A.M.4
Asa, S.L.5
Ezzat, S.6
-
123
-
-
0029330671
-
Immunolocalization of glutathione-peroxidase (GSH-PO) in human adrenal gland-studies on adrenocortical adenomas associated with primary aldosteronism and Cushing's syndrome
-
Murakoshi M., Osamura R.Y., Yoshimura S., Watanabe K. Immunolocalization of glutathione-peroxidase (GSH-PO) in human adrenal gland-studies on adrenocortical adenomas associated with primary aldosteronism and Cushing's syndrome. Tokai J. Exp. Clin. Med. 1995, 20:89-97.
-
(1995)
Tokai J. Exp. Clin. Med.
, vol.20
, pp. 89-97
-
-
Murakoshi, M.1
Osamura, R.Y.2
Yoshimura, S.3
Watanabe, K.4
-
124
-
-
34648833460
-
CAMP and protein kinase A in endocrine (and other) tumors
-
Nesterova M., Stratakis C.A. CAMP and protein kinase A in endocrine (and other) tumors. Exp. Rev. Endocrinol. Metab. 2007, 2:667-676.
-
(2007)
Exp. Rev. Endocrinol. Metab.
, vol.2
, pp. 667-676
-
-
Nesterova, M.1
Stratakis, C.A.2
-
125
-
-
39049144821
-
An immortalized human cell line bearing a PRKAR1A-inactivating mutation: effects of over-expression of the wild-type allele and other protein kinase A (PKA) subunits
-
Nesterova M., Wen F., Horvath A., Matyakhina L., Stratakis C.A. An immortalized human cell line bearing a PRKAR1A-inactivating mutation: effects of over-expression of the wild-type allele and other protein kinase A (PKA) subunits. J. Clin. Endocrinol. Metab. 2008, 93:565-571.
-
(2008)
J. Clin. Endocrinol. Metab.
, vol.93
, pp. 565-571
-
-
Nesterova, M.1
Wen, F.2
Horvath, A.3
Matyakhina, L.4
Stratakis, C.A.5
-
126
-
-
0036711353
-
Familial ACTH-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia clinically affecting only female family members
-
Nies C., Bartsch D.K., Ehlenz K., Wild A., Langer P., Fleischhacker S., Rothmund M. Familial ACTH-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia clinically affecting only female family members. Exp. Clin. Endocrinol. Diabetes 2002, 110:277-283.
-
(2002)
Exp. Clin. Endocrinol. Diabetes
, vol.110
, pp. 277-283
-
-
Nies, C.1
Bartsch, D.K.2
Ehlenz, K.3
Wild, A.4
Langer, P.5
Fleischhacker, S.6
Rothmund, M.7
-
127
-
-
13244287677
-
Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche
-
Nishimura E.K., Granter S.R., Fisher D.E. Mechanisms of hair graying: incomplete melanocyte stem cell maintenance in the niche. Science 2005, 307(5710):720-724.
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 720-724
-
-
Nishimura, E.K.1
Granter, S.R.2
Fisher, D.E.3
-
128
-
-
67650481889
-
Cushing's syndrome by left adrenocortical adenoma synchronously associated with primary aldosteronism by right adrenocortical adenoma: report of a case
-
Onoda N., Ishikawa T., Nishio K., Tahara H., Inaba M., Wakasa K., Sumi T., Yamazaki T., Shigematsu K., Hirakawa K. Cushing's syndrome by left adrenocortical adenoma synchronously associated with primary aldosteronism by right adrenocortical adenoma: report of a case. Endocr. J. 2009, 56:495-502.
-
(2009)
Endocr. J.
, vol.56
, pp. 495-502
-
-
Onoda, N.1
Ishikawa, T.2
Nishio, K.3
Tahara, H.4
Inaba, M.5
Wakasa, K.6
Sumi, T.7
Yamazaki, T.8
Shigematsu, K.9
Hirakawa, K.10
-
129
-
-
33745266737
-
Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases
-
Park J.Y., Pillinger M.H., Abramson S.B. Prostaglandin E2 synthesis and secretion: the role of PGE2 synthases. Clin. Immunol. 2006, 119:229-240.
-
(2006)
Clin. Immunol.
, vol.119
, pp. 229-240
-
-
Park, J.Y.1
Pillinger, M.H.2
Abramson, S.B.3
-
130
-
-
34548707237
-
Multiple gastrointestinal stromal and other tumors caused by platelet-derived growth factor receptor alpha gene mutations: a case associated with a germline V561D defect
-
Pasini B., Matyakhina L., Bei T., Muchow M., Boikos S., Ferrando B., Carney J.A., Stratakis C.A. Multiple gastrointestinal stromal and other tumors caused by platelet-derived growth factor receptor alpha gene mutations: a case associated with a germline V561D defect. J. Clin. Endocrinol. Metab. 2007, 92:3728-3732.
-
(2007)
J. Clin. Endocrinol. Metab.
, vol.92
, pp. 3728-3732
-
-
Pasini, B.1
Matyakhina, L.2
Bei, T.3
Muchow, M.4
Boikos, S.5
Ferrando, B.6
Carney, J.A.7
Stratakis, C.A.8
-
131
-
-
37349074531
-
Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD
-
Pasini B., McWhinney S.R., Bei T., Matyakhina L., Stergiopoulos S., Muchow M., Boikos S.A., Ferrando B., Pacak K., Assie G., Baudin E., Chompret A., Ellison J.W., Briere J.J., Rustin P., Gimenez-Roqueplo A.P., Eng C., Carney J.A., Stratakis C.A. Clinical and molecular genetics of patients with the Carney-Stratakis syndrome and germline mutations of the genes coding for the succinate dehydrogenase subunits SDHB, SDHC, and SDHD. Eur. J. Hum. Genet. 2008, 16:79-88.
-
(2008)
Eur. J. Hum. Genet.
, vol.16
, pp. 79-88
-
-
Pasini, B.1
McWhinney, S.R.2
Bei, T.3
Matyakhina, L.4
Stergiopoulos, S.5
Muchow, M.6
Boikos, S.A.7
Ferrando, B.8
Pacak, K.9
Assie, G.10
Baudin, E.11
Chompret, A.12
Ellison, J.W.13
Briere, J.J.14
Rustin, P.15
Gimenez-Roqueplo, A.P.16
Eng, C.17
Carney, J.A.18
Stratakis, C.A.19
-
132
-
-
84858054011
-
In vitro studies of novel PRKAR1A mutants that extend the predicted R1α protein sequence into the 3'-untranslated open reading frame: proteosomal degradation leads to RIα haploinsufficiency and Carney complex
-
Patronas Y., Horvath A., Greene E., Tsang K., Bimpaki E., Haran M., Nesterova M., Stratakis C.A. In vitro studies of novel PRKAR1A mutants that extend the predicted R1α protein sequence into the 3'-untranslated open reading frame: proteosomal degradation leads to RIα haploinsufficiency and Carney complex. J. Clin. Endocrinol. Metab. 2012, 97:E496-E502.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Patronas, Y.1
Horvath, A.2
Greene, E.3
Tsang, K.4
Bimpaki, E.5
Haran, M.6
Nesterova, M.7
Stratakis, C.A.8
-
133
-
-
38749151856
-
Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A
-
Pavel E., Nadella K., Towns W.H., Kirschner L.S. Mutation of Prkar1a causes osteoblast neoplasia driven by dysregulation of protein kinase A. Mol. Endocrinol. 2008, 22:430-440.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 430-440
-
-
Pavel, E.1
Nadella, K.2
Towns, W.H.3
Kirschner, L.S.4
-
134
-
-
75149196669
-
Association of the M1V PRKAR1A mutation with primary pigmented nodular adrenocortical disease in two large families
-
Pereira A.M., Hes F.J., Horvath A., Woortman S., Greene E., Bimpaki E., Alatsatianos A., Boikos S., Smit J.W., Romijn J.A., Nesterova M., Stratakis C.A. Association of the M1V PRKAR1A mutation with primary pigmented nodular adrenocortical disease in two large families. J. Clin. Endocrinol. Metab. 2010, 95:338-342.
-
(2010)
J. Clin. Endocrinol. Metab.
, vol.95
, pp. 338-342
-
-
Pereira, A.M.1
Hes, F.J.2
Horvath, A.3
Woortman, S.4
Greene, E.5
Bimpaki, E.6
Alatsatianos, A.7
Boikos, S.8
Smit, J.W.9
Romijn, J.A.10
Nesterova, M.11
Stratakis, C.A.12
-
135
-
-
33645074971
-
Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence
-
Perry C.G., Young W.F., McWhinney S.R., Bei T., Stergiopoulos S., Knudson R.A., Ketterling R.P., Eng C., Stratakis C.A., Carney J.A. Functioning paraganglioma and gastrointestinal stromal tumor of the jejunum in three women: syndrome or coincidence. Am. J. Surg. Pathol. 2006, 30:42-49.
-
(2006)
Am. J. Surg. Pathol.
, vol.30
, pp. 42-49
-
-
Perry, C.G.1
Young, W.F.2
McWhinney, S.R.3
Bei, T.4
Stergiopoulos, S.5
Knudson, R.A.6
Ketterling, R.P.7
Eng, C.8
Stratakis, C.A.9
Carney, J.A.10
-
136
-
-
78751509028
-
Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway
-
Qian X., Zhang J., Liu J. Tumor-secreted PGE2 inhibits CCL5 production in activated macrophages through cAMP/PKA signaling pathway. J. Biol. Chem. 2011, 286:2111-2120.
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2111-2120
-
-
Qian, X.1
Zhang, J.2
Liu, J.3
-
137
-
-
3843115756
-
Reduced ocular dominance plasticity and long-term potentiation in the developing visual cortex of protein kinase A RII alpha mutant mice
-
Rao Y., Fischer Q.S., Yang Y., McKnight G.S., LaRue A., Daw N.W. Reduced ocular dominance plasticity and long-term potentiation in the developing visual cortex of protein kinase A RII alpha mutant mice. Eur. J. Neurosci. 2004, 20:837-842.
-
(2004)
Eur. J. Neurosci.
, vol.20
, pp. 837-842
-
-
Rao, Y.1
Fischer, Q.S.2
Yang, Y.3
McKnight, G.S.4
LaRue, A.5
Daw, N.W.6
-
139
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L., Lombardi D.G., Pilozzi E., Biffoni M., Todaro M., Peschle C., De Maria R. Identification and expansion of human colon-cancer-initiating cells. Nature 2007, 445:111-115.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
Biffoni, M.4
Todaro, M.5
Peschle, C.6
De Maria, R.7
-
140
-
-
0030660319
-
Fibrous dysplasia of bone in the McCune-Albright syndrome: abnormalities in bone formation
-
Riminucci M., Fisher L.W., Shenker A., Spiegel A.M., Bianco P., Gehron-Robey P. Fibrous dysplasia of bone in the McCune-Albright syndrome: abnormalities in bone formation. Am. J. Pathol. 1997, 151:1587-1600.
-
(1997)
Am. J. Pathol.
, vol.151
, pp. 1587-1600
-
-
Riminucci, M.1
Fisher, L.W.2
Shenker, A.3
Spiegel, A.M.4
Bianco, P.5
Gehron-Robey, P.6
-
141
-
-
34247857745
-
Fibrous dysplasia as a stem cell disease
-
Riminucci M., Saggio I., Robey P.G., Bianco P. Fibrous dysplasia as a stem cell disease. J. Bone Miner. Res. 2006, 21(Suppl 2):P125-P131.
-
(2006)
J. Bone Miner. Res.
, vol.21
, Issue.SUPPL 2
-
-
Riminucci, M.1
Saggio, I.2
Robey, P.G.3
Bianco, P.4
-
142
-
-
33744955546
-
PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex
-
Robinson-White A., Meoli E., Stergiopoulos S., Horvath A., Boikos S., Bossis I., Stratakis C.A. PRKAR1A Mutations and protein kinase A interactions with other signaling pathways in the adrenal cortex. J. Clin. Endocrinol. Metab. 2006, 91:2380-2388.
-
(2006)
J. Clin. Endocrinol. Metab.
, vol.91
, pp. 2380-2388
-
-
Robinson-White, A.1
Meoli, E.2
Stergiopoulos, S.3
Horvath, A.4
Boikos, S.5
Bossis, I.6
Stratakis, C.A.7
-
143
-
-
33751301602
-
PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes
-
Robinson-White A.J., Leitner W.W., Aleem E., Kaldis P., Bossis I., Stratakis C.A. PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes. Cancer Res. 2006, 66:10603-10612.
-
(2006)
Cancer Res.
, vol.66
, pp. 10603-10612
-
-
Robinson-White, A.J.1
Leitner, W.W.2
Aleem, E.3
Kaldis, P.4
Bossis, I.5
Stratakis, C.A.6
-
145
-
-
84863664769
-
Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumors
-
Rothenbuhler A., Horvath A., Libé R., Faucz F.R., Fratticci A., Sanson M.L., Vezzosi D., Azevedo M., Levi I., Almeida M.Q., Lodish M., Nesterova M., Bertherat J., Stratakis C.A. Identification of novel genetic variants in phosphodiesterase 8B (PDE8B), a cAMP specific phosphodiesterase highly expressed in the adrenal cortex, in a cohort of patients with adrenal tumors. Clin. Endocrinol. (Oxf) 2012, 77:195-199.
-
(2012)
Clin. Endocrinol. (Oxf)
, vol.77
, pp. 195-199
-
-
Rothenbuhler, A.1
Horvath, A.2
Libé, R.3
Faucz, F.R.4
Fratticci, A.5
Sanson, M.L.6
Vezzosi, D.7
Azevedo, M.8
Levi, I.9
Almeida, M.Q.10
Lodish, M.11
Nesterova, M.12
Bertherat, J.13
Stratakis, C.A.14
-
146
-
-
77954152314
-
Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice
-
Sahut-Barnola I., de Joussineau C., Val P., Lambert-Langlais S., Damon C., Lefrançois-Martinez A.M., Pointud J.C., Marceau G., Sapin V., Tissier F., Ragazzon B., Bertherat J., Kirschner L.S., Stratakis C.A., Martinez A. Cushing's syndrome and fetal features resurgence in adrenal cortex-specific Prkar1a knockout mice. PLoS Genet. 2010, 10(6):e1000980.
-
(2010)
PLoS Genet.
, vol.10
, Issue.6
-
-
Sahut-Barnola, I.1
de Joussineau, C.2
Val, P.3
Lambert-Langlais, S.4
Damon, C.5
Lefrançois-Martinez, A.M.6
Pointud, J.C.7
Marceau, G.8
Sapin, V.9
Tissier, F.10
Ragazzon, B.11
Bertherat, J.12
Kirschner, L.S.13
Stratakis, C.A.14
Martinez, A.15
-
147
-
-
0030986161
-
Primary pigmented nodular adrenocortical disease: reevaluation of a patient with carney complex 27 years after unilateral adrenalectomy
-
Sarlis N.J., Chrousos G.P., Doppman J.L., Carney J.A., Stratakis C.A. Primary pigmented nodular adrenocortical disease: reevaluation of a patient with carney complex 27 years after unilateral adrenalectomy. J. Clin. Endocrinol. Metab. 1997, 82:1274-1278.
-
(1997)
J. Clin. Endocrinol. Metab.
, vol.82
, pp. 1274-1278
-
-
Sarlis, N.J.1
Chrousos, G.P.2
Doppman, J.L.3
Carney, J.A.4
Stratakis, C.A.5
-
148
-
-
84863115868
-
Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5
-
Scholl U.I., Nelson-Williams C., Yue P., Grekin R., Wyatt R.J., Dillon M.J., Couch R., Hammer L.K., Harley F.L., Farhi A., Wang W.H., Lifton R.P. Hypertension with or without adrenal hyperplasia due to different inherited mutations in the potassium channel KCNJ5. Proc. Natl. Acad. Sci. USA 2012, 109:2533-2538.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 2533-2538
-
-
Scholl, U.I.1
Nelson-Williams, C.2
Yue, P.3
Grekin, R.4
Wyatt, R.J.5
Dillon, M.J.6
Couch, R.7
Hammer, L.K.8
Harley, F.L.9
Farhi, A.10
Wang, W.H.11
Lifton, R.P.12
-
149
-
-
84876082481
-
Cyclic AMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis
-
in press
-
Shimizu-Albergine, M., Tsai, L.C., Patrucco, E., Beavo, J.A., in press. Cyclic AMP-specific phosphodiesterases 8A and 8B, essential regulators of Leydig cell steroidogenesis. Mol. Pharmacol.
-
Mol. Pharmacol.
-
-
Shimizu-Albergine, M.1
Tsai, L.C.2
Patrucco, E.3
Beavo, J.A.4
-
150
-
-
84856082494
-
Cushing's syndrome in multiple endocrine neoplasia type 1
-
Simonds W.F., Varghese S., Marx S.J., Nieman L.K. Cushing's syndrome in multiple endocrine neoplasia type 1. Clin. Endocrinol. (Oxf) 2012, 76:379-386.
-
(2012)
Clin. Endocrinol. (Oxf)
, vol.76
, pp. 379-386
-
-
Simonds, W.F.1
Varghese, S.2
Marx, S.J.3
Nieman, L.K.4
-
151
-
-
0034241380
-
Specificity in the cAMP/PKA signaling pathway: differential expression, regulation, and subcellular localization of subunits of PKA
-
Skalhegg B.S., Tasken K. Specificity in the cAMP/PKA signaling pathway: differential expression, regulation, and subcellular localization of subunits of PKA. Front Biosci. 2000, 5:D678-D693.
-
(2000)
Front Biosci.
, vol.5
-
-
Skalhegg, B.S.1
Tasken, K.2
-
152
-
-
0036008839
-
Mutation of the Calpha subunit of PKA leads to growth retardation and sperm dysfunction
-
Skålhegg B.S., Huang Y., Su T., Idzerda R.L., McKnight G.S., Burton K.A. Mutation of the Calpha subunit of PKA leads to growth retardation and sperm dysfunction. Mol. Endocrinol. 2002, 16:630-639.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 630-639
-
-
Skålhegg, B.S.1
Huang, Y.2
Su, T.3
Idzerda, R.L.4
McKnight, G.S.5
Burton, K.A.6
-
153
-
-
78650024234
-
Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis
-
Smit D.L., Mensenkamp A.R., Badeloe S., Breuning M.H., Simon M.E., van Spaendonck K.Y., Aalfs C.M., Post J.G., Shanley S., Krapels I.P., Hoefsloot L.H., van Moorselaar R.J., Starink T.M., Bayley J.P., Frank J., van Steensel M.A., Menko F.H. Hereditary leiomyomatosis and renal cell cancer in families referred for fumarate hydratase germline mutation analysis. Clin. Genet. 2011, 79:49-59.
-
(2011)
Clin. Genet.
, vol.79
, pp. 49-59
-
-
Smit, D.L.1
Mensenkamp, A.R.2
Badeloe, S.3
Breuning, M.H.4
Simon, M.E.5
van Spaendonck, K.Y.6
Aalfs, C.M.7
Post, J.G.8
Shanley, S.9
Krapels, I.P.10
Hoefsloot, L.H.11
van Moorselaar, R.J.12
Starink, T.M.13
Bayley, J.P.14
Frank, J.15
van Steensel, M.A.16
Menko, F.H.17
-
154
-
-
0030049026
-
Carney complex, a familial multiple neoplasia and lentiginosis syndrome: analysis of 11 kindreds and linkage to the short arm of chromosome 2
-
Stratakis C.A., Carney J.A., Lin J.P., Papanicolaou D.A., Karl M., Kastner D.L., Pras E., Chrousos G.P. Carney complex, a familial multiple neoplasia and lentiginosis syndrome: analysis of 11 kindreds and linkage to the short arm of chromosome 2. J. Clin. Invest. 1996, 97:699-705.
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 699-705
-
-
Stratakis, C.A.1
Carney, J.A.2
Lin, J.P.3
Papanicolaou, D.A.4
Karl, M.5
Kastner, D.L.6
Pras, E.7
Chrousos, G.P.8
-
155
-
-
0033027686
-
Synaptophysin immunoreactivity in primary pigmented nodular adrenocortical disease: neuroendocrine properties of tumors associated with Carney complex
-
Stratakis C.A., Carney J.A., Kirschner L.S., Willenberg H.S., Brauer S., Ehrhart-Bornstein M., Bornstein S.R. Synaptophysin immunoreactivity in primary pigmented nodular adrenocortical disease: neuroendocrine properties of tumors associated with Carney complex. J. Clin. Endocrinol. Metab. 1999, 84:1122-1128.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 1122-1128
-
-
Stratakis, C.A.1
Carney, J.A.2
Kirschner, L.S.3
Willenberg, H.S.4
Brauer, S.5
Ehrhart-Bornstein, M.6
Bornstein, S.R.7
-
156
-
-
0032697639
-
Paradoxical response to dexamethasone in the diagnosis of primary pigmented nodular adrenocortical disease
-
Stratakis C.A., Sarlis N., Kirschner L.S., Carney J.A., Doppman J.L., Nieman L.K., Chrousos G.P., Papanicolaou D.A. Paradoxical response to dexamethasone in the diagnosis of primary pigmented nodular adrenocortical disease. Ann. Intern. Med. 1999, 131:585-591.
-
(1999)
Ann. Intern. Med.
, vol.131
, pp. 585-591
-
-
Stratakis, C.A.1
Sarlis, N.2
Kirschner, L.S.3
Carney, J.A.4
Doppman, J.L.5
Nieman, L.K.6
Chrousos, G.P.7
Papanicolaou, D.A.8
-
157
-
-
0034853288
-
Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation
-
Stratakis C.A., Kirschner L.S., Carney J.A. Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation. J. Clin. Endocrinol. Metab. 2001, 86:4041-4046.
-
(2001)
J. Clin. Endocrinol. Metab.
, vol.86
, pp. 4041-4046
-
-
Stratakis, C.A.1
Kirschner, L.S.2
Carney, J.A.3
-
158
-
-
34347213389
-
Adrenocortical tumors, primary pigmented adrenocortical disease (PPNAD)/Carney complex, and other bilateral hyperplasias: the NIH studies
-
Stratakis C.A. Adrenocortical tumors, primary pigmented adrenocortical disease (PPNAD)/Carney complex, and other bilateral hyperplasias: the NIH studies. Horm. Metab. Res. 2007, 39:467-473.
-
(2007)
Horm. Metab. Res.
, vol.39
, pp. 467-473
-
-
Stratakis, C.A.1
-
159
-
-
35448973741
-
Genetics of adrenal tumors associated with Cushing's syndrome: a new classification for bilateral adrenocortical hyperplasias
-
Stratakis C.A., Boikos S.A. Genetics of adrenal tumors associated with Cushing's syndrome: a new classification for bilateral adrenocortical hyperplasias. Nat. Clin. Pract. Endocrinol. Metab. 2007, 3:748-757.
-
(2007)
Nat. Clin. Pract. Endocrinol. Metab.
, vol.3
, pp. 748-757
-
-
Stratakis, C.A.1
Boikos, S.A.2
-
160
-
-
48949107188
-
Cushing syndrome caused by adrenocortical tumors and hyperplasias (corticotropin-independent Cushing syndrome)
-
Stratakis C.A. Cushing syndrome caused by adrenocortical tumors and hyperplasias (corticotropin-independent Cushing syndrome). Endocr. Dev. 2008, 13:117-132.
-
(2008)
Endocr. Dev.
, vol.13
, pp. 117-132
-
-
Stratakis, C.A.1
-
161
-
-
59849101194
-
New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors
-
Stratakis C.A. New genes and/or molecular pathways associated with adrenal hyperplasias and related adrenocortical tumors. Mol. Cell. Endocrinol. 2009, 300:152-157.
-
(2009)
Mol. Cell. Endocrinol.
, vol.300
, pp. 152-157
-
-
Stratakis, C.A.1
-
162
-
-
66849135214
-
The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications
-
Stratakis C.A., Carney J.A. The triad of paragangliomas, gastric stromal tumours and pulmonary chondromas (Carney triad), and the dyad of paragangliomas and gastric stromal sarcomas (Carney-Stratakis syndrome): molecular genetics and clinical implications. J. Intern. Med. 2009, 266:43-52.
-
(2009)
J. Intern. Med.
, vol.266
, pp. 43-52
-
-
Stratakis, C.A.1
Carney, J.A.2
-
163
-
-
49649127949
-
Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease
-
Tadjine M., Lampron A., Ouadi L., Horvath A., Stratakis C.A., Bourdeau I. Detection of somatic beta-catenin mutations in primary pigmented nodular adrenocortical disease. Clin. Endocrinol. (Oxf) 2008, 69:367-373.
-
(2008)
Clin. Endocrinol. (Oxf)
, vol.69
, pp. 367-373
-
-
Tadjine, M.1
Lampron, A.2
Ouadi, L.3
Horvath, A.4
Stratakis, C.A.5
Bourdeau, I.6
-
164
-
-
84859378136
-
Expression and mutations of KCNJ5 mRNA in Japanese patients with aldosterone-producing adenomas
-
Taguchi R., Yamada M., Nakajima Y., Satoh T., Hashimoto K., Shibusawa N., Ozawa A., Okada S., Rokutanda N., Takata D., Koibuchi Y., Horiguchi J., Oyama T., Takeyoshi I., Mori M. Expression and mutations of KCNJ5 mRNA in Japanese patients with aldosterone-producing adenomas. J. Clin. Endocrinol. Metab. 2012, 97:1311-1319.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
, pp. 1311-1319
-
-
Taguchi, R.1
Yamada, M.2
Nakajima, Y.3
Satoh, T.4
Hashimoto, K.5
Shibusawa, N.6
Ozawa, A.7
Okada, S.8
Rokutanda, N.9
Takata, D.10
Koibuchi, Y.11
Horiguchi, J.12
Oyama, T.13
Takeyoshi, I.14
Mori, M.15
-
165
-
-
77953715690
-
Targeting Wnt signaling: can we safely eradicate cancer stem cells?
-
Takahashi-Yanaga F., Kahn M. Targeting Wnt signaling: can we safely eradicate cancer stem cells?. Clin. Cancer Res. 2010, 16:3153-3162.
-
(2010)
Clin. Cancer Res.
, vol.16
, pp. 3153-3162
-
-
Takahashi-Yanaga, F.1
Kahn, M.2
-
166
-
-
0030627190
-
Structure, function, and regulation of human cAMP-dependent protein kinases
-
Taskén K., Skålhegg B.S., Taskén K.A., Solberg R., Knutsen H.K., Levy F.O., Sandberg M., Orstavik S., Larsen T., Johansen A.K., Vang T., Schrader H.P., Reinton N.T., Torgersen K.M., Hansson V., Jahnsen T. Structure, function, and regulation of human cAMP-dependent protein kinases. Adv. Second Messenger Phosphoprotein Res. 1997, 31:191-204.
-
(1997)
Adv. Second Messenger Phosphoprotein Res.
, vol.31
, pp. 191-204
-
-
Taskén, K.1
Skålhegg, B.S.2
Taskén, K.A.3
Solberg, R.4
Knutsen, H.K.5
Levy, F.O.6
Sandberg, M.7
Orstavik, S.8
Larsen, T.9
Johansen, A.K.10
Vang, T.11
Schrader, H.P.12
Reinton, N.T.13
Torgersen, K.M.14
Hansson, V.15
Jahnsen, T.16
-
167
-
-
0031733012
-
Human CYP11B2 (aldosterone synthase) maps to chromosome 8q24.3.J
-
Taymans S.E., Pack S., Pak E., Torpy D.J., Zhuang Z., Stratakis C.A. Human CYP11B2 (aldosterone synthase) maps to chromosome 8q24.3.J. Clin. Endocrinol. Metab. 1998, 83:1033-1036.
-
(1998)
Clin. Endocrinol. Metab.
, vol.83
, pp. 1033-1036
-
-
Taymans, S.E.1
Pack, S.2
Pak, E.3
Torpy, D.J.4
Zhuang, Z.5
Stratakis, C.A.6
-
168
-
-
40749093679
-
Mutations associated with succinate dehydrogenase D - related malignant paragangliomas
-
Timmers H.J., Pacak K., Bertherat J., Lenders J.W., Duet M., Eisenhofer G., Stratakis C.A., Niccoli-Sire P., Huy P.T., Burnichon N., Gimenez-Roqueplo A.P. Mutations associated with succinate dehydrogenase D - related malignant paragangliomas. Clin. Endocrinol. (Oxf) 2008, 68:561-566.
-
(2008)
Clin. Endocrinol. (Oxf)
, vol.68
, pp. 561-566
-
-
Timmers, H.J.1
Pacak, K.2
Bertherat, J.3
Lenders, J.W.4
Duet, M.5
Eisenhofer, G.6
Stratakis, C.A.7
Niccoli-Sire, P.8
Huy, P.T.9
Burnichon, N.10
Gimenez-Roqueplo, A.P.11
-
169
-
-
24744454197
-
Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors
-
Tissier F., Cavard C., Groussin L., Perlemoine K., Fumey G., Hagneré A.M., René-Corail F., Jullian E., Gicquel C., Bertagna X., Vacher-Lavenu M.C., Perret C., Bertherat J. Mutations of beta-catenin in adrenocortical tumors: activation of the Wnt signaling pathway is a frequent event in both benign and malignant adrenocortical tumors. Cancer Res. 2005, 65:7622-7627.
-
(2005)
Cancer Res.
, vol.65
, pp. 7622-7627
-
-
Tissier, F.1
Cavard, C.2
Groussin, L.3
Perlemoine, K.4
Fumey, G.5
Hagneré, A.M.6
René-Corail, F.7
Jullian, E.8
Gicquel, C.9
Bertagna, X.10
Vacher-Lavenu, M.C.11
Perret, C.12
Bertherat, J.13
-
170
-
-
83455228533
-
Assessing the emerging oncogene protein kinase C epsilon as a candidate gene in families with Carney complex-2
-
Toledo R.A., Sekiya T., Horvath A., Faucz F., Fragoso M.C., Longuini V.C., Lourenço D.M., Toledo S.P., Stratakis C.A. Assessing the emerging oncogene protein kinase C epsilon as a candidate gene in families with Carney complex-2. Clin Endocrinol. (Oxf) 2012, 76:147-148.
-
(2012)
Clin Endocrinol. (Oxf)
, vol.76
, pp. 147-148
-
-
Toledo, R.A.1
Sekiya, T.2
Horvath, A.3
Faucz, F.4
Fragoso, M.C.5
Longuini, V.C.6
Lourenço, D.M.7
Toledo, S.P.8
Stratakis, C.A.9
-
171
-
-
0031741777
-
Familial hyperaldosteronism type II: description of a large kindred and exclusion of the aldosterone synthase (CYP11B2) gene
-
Torpy D.J., Gordon R.D., Lin J.P., Huggard P.R., Taymans S.E., Stowasser M., Chrousos G.P., Stratakis C.A. Familial hyperaldosteronism type II: description of a large kindred and exclusion of the aldosterone synthase (CYP11B2) gene. J. Clin. Endocrinol. Metab. 1998, 83:3214-3218.
-
(1998)
J. Clin. Endocrinol. Metab.
, vol.83
, pp. 3214-3218
-
-
Torpy, D.J.1
Gordon, R.D.2
Lin, J.P.3
Huggard, P.R.4
Taymans, S.E.5
Stowasser, M.6
Chrousos, G.P.7
Stratakis, C.A.8
-
172
-
-
79953012232
-
The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland
-
Tsai L.C., Shimizu-Albergine M., Beavo J.A. The high-affinity cAMP-specific phosphodiesterase 8B controls steroidogenesis in the mouse adrenal gland. Mol. Pharmacol. 2011, 79:639-648.
-
(2011)
Mol. Pharmacol.
, vol.79
, pp. 639-648
-
-
Tsai, L.C.1
Shimizu-Albergine, M.2
Beavo, J.A.3
-
173
-
-
77952692816
-
Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone
-
Tsang K.M., Starost M.F., Nesterova M., Boikos S.A., Watkins T., Almeida M.Q., Harran M., Li A., Collins M.T., Cheadle C., Mertz E.L., Leikin S., Kirschner L.S., Robey P., Stratakis C.A. Alternate protein kinase A activity identifies a unique population of stromal cells in adult bone. Proc. Natl. Acad. Sci. USA 2010, 107:8683-8688.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 8683-8688
-
-
Tsang, K.M.1
Starost, M.F.2
Nesterova, M.3
Boikos, S.A.4
Watkins, T.5
Almeida, M.Q.6
Harran, M.7
Li, A.8
Collins, M.T.9
Cheadle, C.10
Mertz, E.L.11
Leikin, S.12
Kirschner, L.S.13
Robey, P.14
Stratakis, C.A.15
-
174
-
-
80155188674
-
Cardiac paraganglioma and gastrointestinal stromal tumor: a pediatric case of Carney-Stratakis syndrome
-
Vaughan P., Pabla L., Hobin D., Barron D.J., Parikh D. Cardiac paraganglioma and gastrointestinal stromal tumor: a pediatric case of Carney-Stratakis syndrome. Ann. Thorac. Surg. 2011, 92:1877-1878.
-
(2011)
Ann. Thorac. Surg.
, vol.92
, pp. 1877-1878
-
-
Vaughan, P.1
Pabla, L.2
Hobin, D.3
Barron, D.J.4
Parikh, D.5
-
175
-
-
79960983785
-
The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA
-
Vetter M.M., Zenn H.M., Méndez E., van den Boom H., Herberg F.W., Skålhegg B.S. The testis-specific Cα2 subunit of PKA is kinetically indistinguishable from the common Cα1 subunit of PKA. BMC Biochem. 2011, 12:40.
-
(2011)
BMC Biochem.
, vol.12
, pp. 40
-
-
Vetter, M.M.1
Zenn, H.M.2
Méndez, E.3
van den Boom, H.4
Herberg, F.W.5
Skålhegg, B.S.6
-
176
-
-
33847701740
-
Familial adrenocorticotropin-independent macronodular adrenal hyperplasia with aberrant serotonin and vasopressin adrenal receptors
-
Vezzosi D., Cartier D., Régnier C., Otal P., Bennet A., Parmentier F., Plantavid M., Lacroix A., Lefebvre H., Caron P. Familial adrenocorticotropin-independent macronodular adrenal hyperplasia with aberrant serotonin and vasopressin adrenal receptors. Eur. J. Endocrinol. 2007, 156:21-31.
-
(2007)
Eur. J. Endocrinol.
, vol.156
, pp. 21-31
-
-
Vezzosi, D.1
Cartier, D.2
Régnier, C.3
Otal, P.4
Bennet, A.5
Parmentier, F.6
Plantavid, M.7
Lacroix, A.8
Lefebvre, H.9
Caron, P.10
-
177
-
-
84868611190
-
Phosphodiesterase 11A (PDE11A) gene defects in patients with ACTH-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors
-
Vezzosi D., Libé R., Baudry C., Rizk-Rabin M., Horvath A., Levy I., René-Corail F., Ragazzon B., Stratakis C.A., Vandecasteele G., Bertherat J. Phosphodiesterase 11A (PDE11A) gene defects in patients with ACTH-independent macronodular adrenal hyperplasia (AIMAH): functional variants may contribute to genetic susceptibility of bilateral adrenal tumors. J. Clin. Endocrinol. Metab. 2012, 97:E2063-E2069.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Vezzosi, D.1
Libé, R.2
Baudry, C.3
Rizk-Rabin, M.4
Horvath, A.5
Levy, I.6
René-Corail, F.7
Ragazzon, B.8
Stratakis, C.A.9
Vandecasteele, G.10
Bertherat, J.11
-
178
-
-
79959921466
-
Succinate dehydrogenase subunit B (SDHB) Is expressed in neurofibromatosis 1-associated gastrointestinal stromal tumors (GISTs): implications for the SDHB expression-based classification of GISTs
-
Wang J.H., Lasota J., Miettinen M. Succinate dehydrogenase subunit B (SDHB) Is expressed in neurofibromatosis 1-associated gastrointestinal stromal tumors (GISTs): implications for the SDHB expression-based classification of GISTs. J. Cancer 2011, 2:90-93.
-
(2011)
J. Cancer
, vol.2
, pp. 90-93
-
-
Wang, J.H.1
Lasota, J.2
Miettinen, M.3
-
179
-
-
33644560281
-
Cancer stem cells: an old idea-a paradigm shift
-
Wicha M.S., Liu S., Dontu G. Cancer stem cells: an old idea-a paradigm shift. Cancer Res. 2006, 66:1883-1890.
-
(2006)
Cancer Res.
, vol.66
, pp. 1883-1890
-
-
Wicha, M.S.1
Liu, S.2
Dontu, G.3
-
180
-
-
79954544984
-
Cell-type specific expression of a dominant negative PKA mutation in mice
-
Willis B.S., Niswender C.M., Su T., Amieux P.S., McKnight G.S. Cell-type specific expression of a dominant negative PKA mutation in mice. PLoS ONE 2011, 6:e1877.
-
(2011)
PLoS ONE
, vol.6
-
-
Willis, B.S.1
Niswender, C.M.2
Su, T.3
Amieux, P.S.4
McKnight, G.S.5
-
181
-
-
84858016863
-
Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: A new association for SDH?
-
Xekouki P., Pacak K., Almeida M., Wassif C.A., Rustin P., Nesterova M., de la Luz Sierra M., Matro J., Ball E., Azevedo M., Horvath A., Lyssikatos C., Quezado M., Patronas N., Ferrando B., Pasini B., Lytras A., Tolis G., Stratakis C.A. Succinate dehydrogenase (SDH) D subunit (SDHD) inactivation in a growth-hormone-producing pituitary tumor: A new association for SDH?. J. Clin. Endocrinol. Metab. 2012, 97:E357-E366.
-
(2012)
J. Clin. Endocrinol. Metab.
, vol.97
-
-
Xekouki, P.1
Pacak, K.2
Almeida, M.3
Wassif, C.A.4
Rustin, P.5
Nesterova, M.6
de la Luz Sierra, M.7
Matro, J.8
Ball, E.9
Azevedo, M.10
Horvath, A.11
Lyssikatos, C.12
Quezado, M.13
Patronas, N.14
Ferrando, B.15
Pasini, B.16
Lytras, A.17
Tolis, G.18
Stratakis, C.A.19
-
182
-
-
84862640301
-
KCNJ5 mutations in the National Institutes of Health cohort of patients with primary hyperaldosteronism: an infrequent genetic cause of Conn's syndrome
-
Xekouki P., Hatch M.M., Lin L., Rodrigo D.A., Azevedo M., Sierra M.D., Levy I., Saloustros E., Moraitis A., Horvath A., Kebebew E., Hoffman D., Stratakis C.A. KCNJ5 mutations in the National Institutes of Health cohort of patients with primary hyperaldosteronism: an infrequent genetic cause of Conn's syndrome. Endocr. Relat. Cancer 2012, 19:255-260.
-
(2012)
Endocr. Relat. Cancer
, vol.19
, pp. 255-260
-
-
Xekouki, P.1
Hatch, M.M.2
Lin, L.3
Rodrigo, D.A.4
Azevedo, M.5
Sierra, M.D.6
Levy, I.7
Saloustros, E.8
Moraitis, A.9
Horvath, A.10
Kebebew, E.11
Hoffman, D.12
Stratakis, C.A.13
-
183
-
-
41649121002
-
Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis
-
Yin Z., Jones G.N., Towns W.H., Zhang X., Abel E.D., Binkley P.F., Jarjoura D., Kirschner L.S. Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis. Circulation 2008, 117:1414-1422.
-
(2008)
Circulation
, vol.117
, pp. 1414-1422
-
-
Yin, Z.1
Jones, G.N.2
Towns, W.H.3
Zhang, X.4
Abel, E.D.5
Binkley, P.F.6
Jarjoura, D.7
Kirschner, L.S.8
-
184
-
-
40949119860
-
Development of a pituitary-specific cre line targeted to the Pit-1 lineage
-
Yin Z., Williams-Simons L., Rawahneh L., Asa S., Kirschner L.S. Development of a pituitary-specific cre line targeted to the Pit-1 lineage. Genesis 2008, 46:37-42.
-
(2008)
Genesis
, vol.46
, pp. 37-42
-
-
Yin, Z.1
Williams-Simons, L.2
Rawahneh, L.3
Asa, S.4
Kirschner, L.S.5
-
185
-
-
38749106141
-
Pituitary-specific knockout of the carney complex gene prkar1a leads to pituitary tumorigenesis
-
Yin Z., Williams-Simons L., Parlow A.F., Asa S., Kirschner L.S. Pituitary-specific knockout of the carney complex gene prkar1a leads to pituitary tumorigenesis. Mol. Endocrinol. 2008, 22:380-387.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 380-387
-
-
Yin, Z.1
Williams-Simons, L.2
Parlow, A.F.3
Asa, S.4
Kirschner, L.S.5
-
186
-
-
80053450655
-
Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a
-
Yin Z., Pringle D.R., Jones G.N., Kelly K.M., Kirschner L.S. Differential role of PKA catalytic subunits in mediating phenotypes caused by knockout of the Carney complex gene Prkar1a. Mol. Endocrinol. 2011, 25:1786-1793.
-
(2011)
Mol. Endocrinol.
, vol.25
, pp. 1786-1793
-
-
Yin, Z.1
Pringle, D.R.2
Jones, G.N.3
Kelly, K.M.4
Kirschner, L.S.5
-
187
-
-
73949152219
-
Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases
-
Zhang L., Smyrk T.C., Young W.F., Stratakis C.A., Carney J.A. Gastric stromal tumors in Carney triad are different clinically, pathologically, and behaviorally from sporadic gastric gastrointestinal stromal tumors: findings in 104 cases. Am. J. Surg. Pathol. 2010, 34:53-64.
-
(2010)
Am. J. Surg. Pathol.
, vol.34
, pp. 53-64
-
-
Zhang, L.1
Smyrk, T.C.2
Young, W.F.3
Stratakis, C.A.4
Carney, J.A.5
-
188
-
-
81155149481
-
PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway
-
Zhang Y., Daaka Y. PGE2 promotes angiogenesis through EP4 and PKA Cγ pathway. Blood 2011, 118:5355-5364.
-
(2011)
Blood
, vol.118
, pp. 5355-5364
-
-
Zhang, Y.1
Daaka, Y.2
-
189
-
-
84876080599
-
-
Online Mendelian Inheritance in Man ; entry#606864 paraganglioma and gastric stromal sarcoma.
-
Online Mendelian Inheritance in Man ; entry#606864 paraganglioma and gastric stromal sarcoma. http://www.ncbi.nlm.nih.gov/omim.
-
-
-
|