The prostaglandin E2 receptor, EP2, stimulates keratinocyte proliferation in mouse skin by G protein-dependent and β-arrestin1- dependent signaling pathways

Journal of Biological Chemistry

Volumn 285, Issue 51, 2010, Pages 39672-39681

  Chun, Kyung Soo ^a   Lao, Huei Chen ^a   Langenbach, Robert ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARRESTINS; CAMP-RESPONSE ELEMENT-BINDING PROTEINS; COMPLEX FORMATIONS; EPIDERMAL GROWTH FACTOR RECEPTORS; ERK ACTIVATION; G PROTEIN; G-PROTEIN COUPLED RECEPTORS; GEFITINIB; KERATINOCYTES; MEDIATED SIGNALING PATHWAYS; MOUSE SKIN; PROSTAGLANDINE; SIGNALING COMPLEX; SIGNALING PATHWAYS; SKIN TUMOR; TOPICAL APPLICATION;

FETAL MONITORING; SIGNALING; TUMORS;

PROTEINS;

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ADENOSINE 3',5' CYCLIC MONOPHOSPHOROTHIOATE; BETA ARRESTIN 1; BUTAPROST; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; G PROTEIN COUPLED RECEPTOR; GEFITINIB; GLYCOGEN SYNTHASE KINASE 3BETA; GUANINE NUCLEOTIDE BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; PROSTAGLANDIN E RECEPTOR; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; STAT3 PROTEIN; UNCLASSIFIED DRUG; BETA ARRESTIN; DRUG DERIVATIVE; EGFR PROTEIN, MOUSE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MULTIPROTEIN COMPLEX; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E1; PROTEIN KINASE INHIBITOR; QUINAZOLINE DERIVATIVE; RETINA S ANTIGEN; STAT3 PROTEIN, MOUSE; TYRPHOSTIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL PROLIFERATION; CELL STIMULATION; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REGULATION; FEMALE; KERATINOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN PROTEIN INTERACTION; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; ANIMAL; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PHYSIOLOGY; SKIN;

ALPROSTADIL; ANIMALS; ARRESTINS; CELL PROLIFERATION; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; GLYCOGEN SYNTHASE KINASE 3; GTP-BINDING PROTEINS; KERATINOCYTES; MICE; MITOGEN-ACTIVATED PROTEIN KINASE 3; MULTIPROTEIN COMPLEXES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; SIGNAL TRANSDUCTION; SKIN; SRC-FAMILY KINASES; STAT3 TRANSCRIPTION FACTOR; TYRPHOSTINS;

EID: 78650057361     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.117689     Document Type: Article

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