Fibrous dysplasia of bone in the McCune-Albright syndrome: Abnormalities in bone formation

American Journal of Pathology

Volumn 151, Issue 6, 1997, Pages 1587-1600

  Riminucci, Mara ^a,c   Fisher, Larry W ^a   Shenker, Andrew ^b,d   Spiegel, Allen M ^b   Bianco, Paolo ^c   Robey, Pamela Gehron ^a  

^a NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

^d NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; OSTEONECTIN; OSTEOPONTIN; SIALOPROTEIN; VERSICAN;

ADOLESCENT; ADULT; ALBRIGHT SYNDROME; ARTICLE; BONE MATRIX; CAFE AU LAIT SPOT; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FIBROUS DYSPLASIA; HUMAN; HUMAN CELL; MALE; MISSENSE MUTATION; OSSIFICATION; OSTEOBLAST; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ADOLESCENT; ALKALINE PHOSPHATASE; BONE AND BONES; BONE MATRIX; BUCLADESINE; CELLS, CULTURED; CHILD; DNA PRIMERS; FEMALE; FIBROBLASTS; FIBROUS DYSPLASIA, POLYOSTOTIC; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HUMANS; IN SITU HYBRIDIZATION; MALE; ONCOGENE PROTEINS; OSTEONECTIN; POLYMERASE CHAIN REACTION; RNA, MESSENGER; UP-REGULATION;

EID: 0030660319     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. Albright F, Butler AM, Hampton AO, Smith P: Syndrome characterized by osteitis fibrosa disseminata, areas of pigmentation and endocrine dysfunction with precocious puberty in females. N Engl J Med 1937, 216:727-746
2. Danon M, Crawford JD: The McCune-Albright syndrome. Ergeb Inn Med Kinderheilkd 1987, 55:81-115
3. Weinstein LS, Shenker A, Gejman PV, Merino MJ, Friedman E, Spiegel AM: Activating mutations of the stimulatory G protein in the McCune-Albright Syndrome. N Engl J Med 1991, 325:1688-1695
4. Schwindinger WF, Francomano CA, Levine MA: Identification of a mutation in the gene encoding the α subunit of the stimulatory G protein of adenylyl cyclase in McCune-Albright syndrome. Proc Natl Acad Sci USA 1992, 89:5152-5156
5. Shenker A, Weinstein LS, Moran A, Pescovitz OH, Charest NJ, Boney CM, Van Wyk JJ, Merino MJ, Feuillan PP, Spiegel AM: Severe endocrine and nonendocrine manifestations of the McCune-Albright syndrome associated with activating mutations of stimulatory G protein Gs. J Pediatr 1993, 123:509-518
6. Malchoff CD, Reardon G, MacGillivray DC, Yamase H, Rogol AD, Malchoff DM. An unusual presentation of McCune-Albright syndrome confirmed by an activating mutation of the Gs α-subunit from a bone lesion. J Clin Endocrinol Metab 1994, 78:803-806
7. Shenker A, Weinstein LS, Sweet DE, Spiegel AM: An activating Gs α mutation is present in fibrous dysplasia of bone in the McCune-Albright syndrome. J Clin Endocrinol Metab 1994, 79:750-755
8. Candeliere GA, Glorieux FH, Prud'homme J, St-Arnaud R: Increased expression of the c-fos proto-oncogene in bone from patients with fibrous dysplasia. N Engl J Med 1995, 332:1546-1551
9. Yamamoto T, Ozono K, Kasayama S, Yoh K, Hiroshima K, Takagi M, Matsumoto S, Michigami T, Yamaoka K, Kishimoto T, Okada S: Increased IL-6 production by cells isolated from the fibrous bone dysplasia tissues in patients with McCune-Albright syndrome. J Clin Invest 1996, 98:30-35
10. Marie PJ, de Pollak C, Chanson P, Lomri A: Increased proliferation of osteoblastic cells expressing the activating Gs α mutation in monostotic and polyostotic fibrous dysplasia. Am J Pathol 1997, 150:1059-1069
11. Shenker A, Chanson P, Weinstein LS, Chi P, Spiegel AM, Lomri A, Marie PJ: Osteoblastic cells derived from isolated lesions of fibrous dysplasia contain activating somatic mutations of the Gs α gene. Hum Mol Genet 1995, 4:1675-1676
12. Alman BA, Greel DA, Wolfe HJ: Activating mutations of Gs protein in monostotic fibrous lesions of bone. J Orthop Res 1996, 14:311-315
13. Bianco P, Boyde A: Alkaline phosphatase cytochemistry in confocal scanning light microscopy for imaging the bone marrow stroma. Basic Appl Histochem 1989, 33:17-23
14. Fisher LW, Stubbs JTR, Young MF: Antisera and cDNA probes to human and certain animal model bone matrix noncollagenous proteins. Acta Orthop Scand Suppl 1995, 266:61-65
15. Simonds WF, Goldsmith PK, Woodard CJ, Unson CG, Spiegel AM: Receptor and effector interactions of Gs: functional studies with antibodies to the α s carboxyl-terminal decapeptide. FEBS Lett 1989, 249:189-194
16. Gehron Robey P, Bianco P, Termine JD: The cellular biology and molecular biochemistry of bone formation. Disorders of Bone and Mineral Metabolism. Edited by Coe FL, Favus MJ. New York, Raven Press, 1992, pp 241-263
17. Bianco P, Riminucci M, Bonucci E, Termine JD, Gehron Robey P: Bone sialoprotein (BSP) and osteoblast differentiation: relationship to alkaline phosphatase, bromodeoxyuridine incorporation, and matrix deposition. J Histochem Cytochem 1993, 41:183-191
18. Gehron Robey PG, Termine JD: Human bone cells in vitro. Calcif Tissue Int 1985, 37:453-460
19. Owen M: The origin of bone cells. Int Rev Cytol 1970, 28:213-238
20. Greco MA, Steiner GC: Ultrastructure of fibrous dysplasia of bone: a study of its fibrous, osseous, and cartilaginous components. Ultrastruct Pathol 1986, 10:55-66
21. Bianco P: Structure and mineralization of bone. Mineralization in Biological Systems. Edited by Bonucci E, Boca Raton, FL, CRC Press, 1992, pp 243-268
22. Miller SS, Wolf AM, Arnaud CD: Bone cells in culture: morphologic transformation by hormones. Science 1976, 192:1340-1343
23. Fedarko NS, Termine JD, Young MF, Robey PG: Temporal regulation of hyaluronan and proteoglycan metabolism by human bone cells in vitro. J Biol Chem 1990, 265:12200-12209
24. Bianco P, Fisher LW, Young MF, Termine JD, Robey PG: Expression and localization of the two small proteoglycans biglycan and decorin in developing human skeletal and non-skeletal tissues. J Histochem Cytochem 1990, 38:1549-1563
25. Bianco P, Silvestrini G, Termine JD, Bonucci E. Immunohistochemical localization of osteonectin in developing human and calf bone using monoclonal antibodies. Calcif Tissue Int 1988, 43:155-161
26. Bianco P, Fisher LW, Young MF, Termine JD, Robey PG: Expression of bone sialoprotein (BSP) in developing human tissues. Calcif Tissue Int 1991, 49:421-426
27. Mark MP, Butler WT, Prince CW, Finkelman RD, Ruch JV: Developmental expression of 44-kd bone phosphoprotein (osteopontin) and bone γ-carboxyglutamic acid (Gla)-containing protein (osteocalcin) in calcifying tissues of rat. Differentiation 1988, 37:123-136
28. Mintz KP, Grzesik WJ, Midura RJ, Robey PG, Termine JD, Fisher LW: Purification and fragmentation of nondenatured bone sialoprotein: evidence for a cryptic, RGD-resistant cell attachment domain. J Bone Miner Res 1993, 8:985-995
29. Denhardt DT, Lopez CA, Rollo EE, Hwang SM, An XR, Walther SE: Osteopontin-induced modifications of cellular functions. Ann NY Acad Sci 1995, 760:127-142
30. Rodan GA, Martin TJ: Role of osteoblasts in hormonal control of bone resorption: a hypothesis. Calcif Tissue Int 1981, 33:349-351
31. Bianco P, Bonucci E: Endosteal surfaces in hyperparathyroidism: an enzyme cytochemical study on low temperature processed glycol methacrylate embedded bone biopsies. Virchows Arch A Pathol Anat Histopathol 1991, 419:425-431
32. Kopp JB, Robey PG, Termine JD: Osteonectin promoter: DNA sequence analysis and S1 endonuclease site potentially associated with transcriptional control in bone cells. J biol chem 1989, 264:450-456
33. Kerr JM, Fisher LW, Termine JD, Wang MG, McBride OW, Young MF: The human bone sialoprotein gene (IBSP): genomic localization and characterization. Genomics 1993, 17:408-415
34. Everitt EA, Sage EH: Expression of SPARC is correlated with altered morphologies in transfected F9 embryonal carcinoma cells. Exp Cell Res 1992, 199:134-146
35. Noda M, Rodan GA: Transcriptional regulation of osteopontin production in rat osteoblast-like cells by parathyroid hormone. J Cell Biol 1989, 108:713-718