메뉴 건너뛰기




Volumn 93, Issue 2, 2008, Pages 565-571

An immortalized human cell line bearing a PRKAR1A-inactivating mutation: Effects of overexpression of the wild-type allele and other protein kinase A subunits

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN PRKAR1A; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 39049144821     PISSN: 0021972X     EISSN: 0021972X     Source Type: Journal    
DOI: 10.1210/jc.2007-1902     Document Type: Article
Times cited : (34)

References (30)
  • 1
    • 0242696220 scopus 로고    scopus 로고
    • Genetics of adrenocortical tumors: Gatekeepers, landscapers and conductors in symphony
    • Stratakis CA 2003 Genetics of adrenocortical tumors: gatekeepers, landscapers and conductors in symphony. Trends Endocrinol Metab 14:404-410
    • (2003) Trends Endocrinol Metab , vol.14 , pp. 404-410
    • Stratakis, C.A.1
  • 2
    • 0027934280 scopus 로고
    • Activating mutation in the stimulatory guanine nucleotide-binding protein in an infant with Cushing's syndrome and nodular adrenal hyperplasia
    • Boston BA, Mandel S, LaFranchi S, Bliziotes M 1994 Activating mutation in the stimulatory guanine nucleotide-binding protein in an infant with Cushing's syndrome and nodular adrenal hyperplasia. J Clin Endocrinol Metab 79:890-893
    • (1994) J Clin Endocrinol Metab , vol.79 , pp. 890-893
    • Boston, B.A.1    Mandel, S.2    LaFranchi, S.3    Bliziotes, M.4
  • 7
    • 0029737861 scopus 로고    scopus 로고
    • Genetically lean mice result from targeted disruption of the RIIβ subunit of protein kinase A
    • Cummings DE, Brandon EP, Planas JV, Motamed K, Idzerda RL, McKnight GS 1996 Genetically lean mice result from targeted disruption of the RIIβ subunit of protein kinase A. Nature 382:622-626
    • (1996) Nature , vol.382 , pp. 622-626
    • Cummings, D.E.1    Brandon, E.P.2    Planas, J.V.3    Motamed, K.4    Idzerda, R.L.5    McKnight, G.S.6
  • 8
    • 0029671412 scopus 로고    scopus 로고
    • Overexpression of RIIβ regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by sitedirected mutation of RIIβ
    • Nesterova MV, Yokozaki H, McDuffie E, Cho-Chung YS 1996 Overexpression of RIIβ regulatory subunit of protein kinase A in human colon carcinoma cell induces growth arrest and phenotypic changes that are abolished by sitedirected mutation of RIIβ. Eur J Biochem 235:486-494
    • (1996) Eur J Biochem , vol.235 , pp. 486-494
    • Nesterova, M.V.1    Yokozaki, H.2    McDuffie, E.3    Cho-Chung, Y.S.4
  • 9
    • 10044253425 scopus 로고    scopus 로고
    • ACAP signaling complexes: Focal points in space and time
    • Wang W, Scott JD 2004 ACAP signaling complexes: focal points in space and time. Nat Rev Mol Cell Biol 5:959-970
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 959-970
    • Wang, W.1    Scott, J.D.2
  • 10
    • 0034853288 scopus 로고    scopus 로고
    • Clinical and molecular features of the Carney complex: Diagnostic criteria and recommendations for patient evaluation
    • Stratakis CA, Kirschner LS, Carney JA 2001 Clinical and molecular features of the Carney complex: diagnostic criteria and recommendations for patient evaluation. J Clin Endocrinol Metab 86:4041-4046
    • (2001) J Clin Endocrinol Metab , vol.86 , pp. 4041-4046
    • Stratakis, C.A.1    Kirschner, L.S.2    Carney, J.A.3
  • 11
    • 84991575264 scopus 로고    scopus 로고
    • Primary pigmented nodular adrenocortical disease (PPNAD): Paradoxical responses of cortisol secretion to dexamethasone occur in vitro and are associated with increased expression of the glucocorticoid receptor
    • Bourdeau I, Lacroix A, Schurch W, Caron P, Antakly T, Stratakis CA 2003 Primary pigmented nodular adrenocortical disease (PPNAD): paradoxical responses of cortisol secretion to dexamethasone occur in vitro and are associated with increased expression of the glucocorticoid receptor. J Clin Endocrinol Metab 63:5308-5319
    • (2003) J Clin Endocrinol Metab , vol.63 , pp. 5308-5319
    • Bourdeau, I.1    Lacroix, A.2    Schurch, W.3    Caron, P.4    Antakly, T.5    Stratakis, C.A.6
  • 13
    • 0034642302 scopus 로고    scopus 로고
    • Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex
    • Kirschner LS, Sandrini F, Monbo J, Lin JP, Carney JA, Stratakis CA 2000 Genetic heterogeneity and spectrum of mutations of the PRKAR1A gene in patients with the Carney complex. Hum Mol Genet 9:3037-3046
    • (2000) Hum Mol Genet , vol.9 , pp. 3037-3046
    • Kirschner, L.S.1    Sandrini, F.2    Monbo, J.3    Lin, J.P.4    Carney, J.A.5    Stratakis, C.A.6
  • 14
    • 33751301602 scopus 로고    scopus 로고
    • PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes
    • Robinson-White AJ, Leitner WW, Aleem E, Kaldis P, Bossis I, Stratakis CA 2006 PRKAR1A inactivation leads to increased proliferation and decreased apoptosis in human B lymphocytes. Cancer Res 66:10603-10612
    • (2006) Cancer Res , vol.66 , pp. 10603-10612
    • Robinson-White, A.J.1    Leitner, W.W.2    Aleem, E.3    Kaldis, P.4    Bossis, I.5    Stratakis, C.A.6
  • 15
    • 9944245504 scopus 로고    scopus 로고
    • Protein kinase A isozyme switching: Eliciting differential cAMP signaling and tumor reversion
    • Neary CL, Nesterova M, Cho YS, Cheadle C, Becker KG, Cho-Chung YS 2004 Protein kinase A isozyme switching: eliciting differential cAMP signaling and tumor reversion. Oncogene 23:8847-8856
    • (2004) Oncogene , vol.23 , pp. 8847-8856
    • Neary, C.L.1    Nesterova, M.2    Cho, Y.S.3    Cheadle, C.4    Becker, K.G.5    Cho-Chung, Y.S.6
  • 18
    • 9444247656 scopus 로고    scopus 로고
    • PRKAR1A: Normal and abnormal functions
    • Bossis I, Stratakis CA 2004 PRKAR1A: normal and abnormal functions. Endocrinology 145:5452-5458
    • (2004) Endocrinology , vol.145 , pp. 5452-5458
    • Bossis, I.1    Stratakis, C.A.2
  • 24
    • 0023658426 scopus 로고
    • Isolation of a cDNA and characterization of the 5′ flanking region of the gene encoding the type I regulatory subunit of the cAMP-dependent protein kinase
    • Nowak I, Seipel K, Schwarz M, Jans D, Hemmings B 1987 Isolation of a cDNA and characterization of the 5′ flanking region of the gene encoding the type I regulatory subunit of the cAMP-dependent protein kinase. Eur J Biochem 167:27-33
    • (1987) Eur J Biochem , vol.167 , pp. 27-33
    • Nowak, I.1    Seipel, K.2    Schwarz, M.3    Jans, D.4    Hemmings, B.5
  • 28
    • 0036907704 scopus 로고    scopus 로고
    • Grousson L, Kirschner LS, Vincent-Dejean C, Perlemoine K, Jullian E, Delemer B, Zacharieva S, Pignatelli D, Carney JA, Luton JP, Bertagna X, Stratakis C, Bertherat J 2002 Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology: augmented PKA signaling is associated with adrenal tumorigenesis in PPNAD. Am J Hum Genet 71:1433-1442
    • Grousson L, Kirschner LS, Vincent-Dejean C, Perlemoine K, Jullian E, Delemer B, Zacharieva S, Pignatelli D, Carney JA, Luton JP, Bertagna X, Stratakis C, Bertherat J 2002 Molecular analysis of the cyclic AMP-dependent protein kinase A (PKA) regulatory subunit 1A (PRKAR1A) gene in patients with Carney complex and primary pigmented nodular adrenocortical disease (PPNAD) reveals novel mutations and clues for pathophysiology: augmented PKA signaling is associated with adrenal tumorigenesis in PPNAD. Am J Hum Genet 71:1433-1442
  • 29
    • 33750920705 scopus 로고    scopus 로고
    • Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis
    • Degregori J, Johnson DG 2006 Distinct and overlapping roles for E2F family members in transcription, proliferation and apoptosis. Curr Mol Med 6:739-748
    • (2006) Curr Mol Med , vol.6 , pp. 739-748
    • Degregori, J.1    Johnson, D.G.2
  • 30
    • 28544445921 scopus 로고    scopus 로고
    • Disruption of protein kinase A regulation causes immortalization and dysregulation of D-type cyclins
    • Nadella KS, Kirschner LS 2005 Disruption of protein kinase A regulation causes immortalization and dysregulation of D-type cyclins. Cancer Res 65: 10307-10315
    • (2005) Cancer Res , vol.65 , pp. 10307-10315
    • Nadella, K.S.1    Kirschner, L.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.