Distinct roles of β-arrestin 1 and β-arrestin 2 in ORG27569-induced biased signaling and internalization of the cannabinoid receptor 1 (CB1)

Journal of Biological Chemistry

Volumn 288, Issue 14, 2013, Pages 9790-9800

  Ahn, Kwang H ^a   Mahmoud, Mariam M ^a   Shim, Joong Youn ^b   Kendall, Debra A ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b NORTH CAROLINA CENTRAL UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSTERIC MODULATORS; BINDING AFFINITIES; CANNABINOID RECEPTORS; DOWNSTREAM EFFECTS; G PROTEIN COUPLED RECEPTORS; RECEPTOR BINDING; RED FLUORESCENT PROTEINS; SIGNALING MECHANISMS;

BINDING ENERGY; PROTEINS; SIGNALING;

CELL SIGNALING;

4 (1,1 DIMETHYLHEPTYL) 1',2',3',4',5',6' HEXAHYDRO 2,3' DIHYDROXY 6' (3 HYDROXYPROPYL)BIPHENYL; BETA ARRESTIN 1; BETA ARRESTIN 2; CANNABINOID 1 RECEPTOR; CANNABINOID 1 RECEPTOR AGONIST; GREEN FLUORESCENT PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; ORG 27569; PROTEIN TYROSINE KINASE; RED FLUORESCENT PROTEIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ALLOSTERISM; ARTICLE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; INTERNALIZATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SIGNAL TRANSDUCTION;

ALLOSTERIC SITE; ANIMALS; ARRESTINS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; GTP-BINDING PROTEINS; HEK293 CELLS; HUMANS; INDOLES; LUMINESCENT PROTEINS; MICROSCOPY, CONFOCAL; PIPERIDINES; PROTEIN CONFORMATION; PROTEIN ISOFORMS; PROTEIN STRUCTURE, SECONDARY; RATS; RECEPTOR, CANNABINOID, CB1; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

RATTUS;

EID: 84875974450     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.438804     Document Type: Article

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