Small-molecule agonists for the glucagon-like peptide 1 receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 104, Issue 3, 2007, Pages 937-942

  Knudsen, Lotte Bjerre ^a   Kiel, Dan ^b   Teng, Min ^b   Behrens, Carsten ^a   Bhumralkar, Dilip ^b   Kodra, János T ^a   Holst, Jens J ^c   Jeppesen, Claus B ^a   Johnson, Michael D ^b   De Jong, Johannes Cornelis ^a   Jorgensen, Anker Steen ^a   Kercher, Tim ^b   Kostrowicki, Jarek ^b   Madsen, Peter ^a   Olesen, Preben H ^a   Petersen, Jacob S ^a   Poulsen, Fritz ^a   Sidelmann, Ulla G ^a   Sturis, Jeppe ^a   Truesdale, Larry ^b   May, John ^b   Lau, Jesper ^a   more..

^a NOVO NORDISK A S   (Denmark)

^b PFIZER INC   (United States)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Ago allosteric modulator; Allosteric; cAMP; G protein coupled receptor; Screening

Indexed keywords

2 (2' METHYL)THIADIAZOLYLSULFANYL 3 TRIFLUOROMETHYL 6,7 DICHLOROQUINOXALINE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; LIRAGLUTIDE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ALLOSTERISM; ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; INSULIN RELEASE; KNOCKOUT MOUSE; MALE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET; PRIORITY JOURNAL; RAT; WEIGHT REDUCTION;

ANIMALS; CELLS, CULTURED; CRICETINAE; DRUG EVALUATION, PRECLINICAL; GLUCAGON-LIKE PEPTIDES; HUMANS; INSULIN; MICE; MICE, KNOCKOUT; MOLECULAR STRUCTURE; PANCREAS; PERFUSION; QUINOXALINES; RECEPTORS, GLUCAGON; SULFONES; THIADIAZOLES;

MUS; RATTUS;

EID: 33846477446     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0605701104     Document Type: Article

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