-
1
-
-
33644982044
-
Regulation of immune responses by T cells
-
PMid:16540617
-
Jiang H, Chess L. Regulation of immune responses by T cells. N Engl J Med 2006; 354: 1166-1176. http://dx.doi.org/10.1056/NEJMra055446 PMid:16540617
-
(2006)
N Engl J Med
, vol.354
, pp. 1166-1176
-
-
Jiang, H.1
Chess, L.2
-
2
-
-
43949105866
-
Regulatory T cells and immune tolerance
-
PMid:18510923
-
Sakaguchi S, Yamaguchi T, Nomura T, Ono M. Regulatory T cells and immune tolerance. Cell 2008; 133: 775-787. http://dx.doi.org/10.1016/j.cell.2008.05.009 PMid:18510923
-
(2008)
Cell
, vol.133
, pp. 775-787
-
-
Sakaguchi, S.1
Yamaguchi, T.2
Nomura, T.3
Ono, M.4
-
3
-
-
33746599842
-
Regulatory T cells in cancer
-
PMid:16861339
-
Beyer M, Schultze JL. Regulatory T cells in cancer. Blood 2006; 108: 804-811. http://dx.doi.org/10.1182/blood-2006-02-002774 PMid:16861339
-
(2006)
Blood
, vol.108
, pp. 804-811
-
-
Beyer, M.1
Schultze, J.L.2
-
4
-
-
0014792798
-
Cell interactions in the induction of tolerance: the role of thymic lymphocytes
-
PMid:4911896 PMCid:1455602
-
Gershon R, Kondo K. Cell interactions in the induction of tolerance: the role of thymic lymphocytes. Immunology 1970; 18: 723-737. PMid:4911896 PMCid:1455602
-
(1970)
Immunology
, vol.18
, pp. 723-737
-
-
Gershon, R.1
Kondo, K.2
-
5
-
-
0029150110
-
Immunologic tolerance maintained by activated T cells expressing IL-2 receptor a-chain (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases
-
PMid:7636184
-
Sakaguchi S, Sakaguchi N, Asano M, Itoh M, Toda M. Immunologic tolerance maintained by activated T cells expressing IL-2 receptor a-chain (CD25): breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J Immunol 1995; 155: 1151-1164. PMid:7636184
-
(1995)
J Immunol
, vol.155
, pp. 1151-1164
-
-
Sakaguchi, S.1
Sakaguchi, N.2
Asano, M.3
Itoh, M.4
Toda, M.5
-
6
-
-
0019787148
-
T cell growth factor receptors
-
PMid:6975347 PMCid:2186509
-
Robb RJ, Munck A, Smith KA. T cell growth factor receptors. Quantitation, specificity, and biological relevance. J Exp Med 1981; 154: 1455-1474. http://dx.doi.org/10.1084/jem.154.5.1455 PMid:6975347 PMCid:2186509
-
(1981)
Quantitation, specificity, and biological relevance. J Exp Med
, vol.154
, pp. 1455-1474
-
-
Robb, R.J.1
Munck, A.2
Smith, K.A.3
-
7
-
-
0035413350
-
CD4+CD25high regulatory cells in human peripheral blood
-
PMid:11466340
-
Baecher-Allan C, Brown JA, Freeman GJ, Hafler DA. CD4+CD25high regulatory cells in human peripheral blood. J Immunol 2001; 167: 1245-1253. PMid:11466340
-
(2001)
J Immunol
, vol.167
, pp. 1245-1253
-
-
Baecher-Allan, C.1
Brown, J.A.2
Freeman, G.J.3
Hafler, D.A.4
-
8
-
-
1242295285
-
Human CD4+CD25+ regulatory T cells
-
PMid:15036232
-
Baecher-Allan C, Viglietta V, Hafler DA. Human CD4+CD25+ regulatory T cells. Semin Immunol 2004; 16: 89-97. http://dx.doi.org/10.1016/j.smim.2003.12.005 PMid:15036232
-
(2004)
Semin Immunol
, vol.16
, pp. 89-97
-
-
Baecher-Allan, C.1
Viglietta, V.2
Hafler, D.A.3
-
9
-
-
33746356813
-
Human regulatory T cells and their role in autoimmune disease
-
PMid:16903916
-
Baecher-Allan C, Hafler DA. Human regulatory T cells and their role in autoimmune disease. Immunol Rev 2006; 212: 203-216. http://dx.doi.org/10.1111/j.0105-2896.2006.00417.x PMid:16903916
-
(2006)
Immunol Rev
, vol.212
, pp. 203-216
-
-
Baecher-Allan, C.1
Hafler, D.A.2
-
10
-
-
0035180067
-
Control of intestinal inflammation by regulatory T cells
-
PMid:11722634
-
Singh B, Read S, Asseman C, Malstrom V, Mottet C, Stephens LA, Stepankova R, Tlaskalova H, Powrie F. Control of intestinal inflammation by regulatory T cells. Immunol Rev 2001; 182: 190-200. http://dx.doi.org/10.1034/j.1600-065X.2001.1820115.x PMid:11722634
-
(2001)
Immunol Rev
, vol.182
, pp. 190-200
-
-
Singh, B.1
Read, S.2
Asseman, C.3
Malstrom, V.4
Mottet, C.5
Stephens, L.A.6
Stepankova, R.7
Tlaskalova, H.8
Powrie, F.9
-
11
-
-
33847647528
-
Regulatory T cells and cancer
-
PMid:17306521
-
Wang HY, Wang RF. Regulatory T cells and cancer. Curr Opin Immunol 2007; 19: 217-223. http://dx.doi.org/10.1016/j.coi.2007.02.004 PMid:17306521
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 217-223
-
-
Wang, H.Y.1
Wang, R.F.2
-
12
-
-
16844369607
-
Natural regulatory T cells in infectious disease
-
PMid:15785761
-
Belkaid Y, Rouse BT. Natural regulatory T cells in infectious disease. Nat Immunol 2005; 6: 353-360. http://dx.doi.org/10.1038/ni1181 PMid:15785761
-
(2005)
Nat Immunol
, vol.6
, pp. 353-360
-
-
Belkaid, Y.1
Rouse, B.T.2
-
13
-
-
0347785480
-
Control of regulatory T cell development by the transcription factor FoxP3
-
PMid:12522256
-
Hori S, Nomura T, Sakaguchi S. Control of regulatory T cell development by the transcription factor FoxP3. Science 2003; 299: 1057-1061. http://dx.doi.org/10.1126/science.1079490 PMid:12522256
-
(2003)
Science
, vol.299
, pp. 1057-1061
-
-
Hori, S.1
Nomura, T.2
Sakaguchi, S.3
-
14
-
-
0037385330
-
FOXP3 programs the development and function of CD4+CD25+ regulatory T-cells
-
PMid:12612578
-
Fontenot JD, Gavin MA, Rudensky AY. FOXP3 programs the development and function of CD4+CD25+ regulatory T-cells. Nat Immunol 2003; 4: 330-336. http://dx.doi.org/10.1038/ni904 PMid:12612578
-
(2003)
Nat Immunol
, vol.4
, pp. 330-336
-
-
Fontenot, J.D.1
Gavin, M.A.2
Rudensky, A.Y.3
-
15
-
-
16844363097
-
A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor FoxP3
-
PMid:15785758
-
Rudensky AY, Fontenot JD. A well adapted regulatory contrivance: regulatory T cell development and the forkhead family transcription factor FoxP3. Nature Immunol 2005; 6: 331-337. http://dx.doi.org/10.1038/ni1179 PMid:15785758
-
(2005)
Nature Immunol
, vol.6
, pp. 331-337
-
-
Rudensky, A.Y.1
Fontenot, J.D.2
-
16
-
-
33745813929
-
Expression of interleukin (IL)-2 and IL-7 receptors discriminate between human regulatory and activated T cells
-
PMid:16818676 PMCid:2118333
-
Seddiki N, Santner-Nanan B, Martinson J, Zaunders J, Sasson S, Landay A, Solomon M, Selby W, Alexander SI, Nanan R, Kelleher A, Fazekas de St Groth B. Expression of interleukin (IL)-2 and IL-7 receptors discriminate between human regulatory and activated T cells. J Exp Med 2006; 203: 1693-1700. http://dx.doi.org/10.1084/jem.20060468 PMid:16818676 PMCid:2118333
-
(2006)
J Exp Med
, vol.203
, pp. 1693-1700
-
-
Seddiki, N.1
Santner-Nanan, B.2
Martinson, J.3
Zaunders, J.4
Sasson, S.5
Landay, A.6
Solomon, M.7
Selby, W.8
Alexander, S.I.9
Nanan, R.10
Kelleher, A.11
Fazekas de St Groth, B.12
-
17
-
-
33745817085
-
CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells
-
PMid:16818678 PMCid:2118339
-
Liu W, Putnam AL, Xu-Yu Z, Szot GL, Lee MR, Zhu S, Gottlieb PA, Kapranov P, Gingeras TR, Fazekas de St Groth B, Clayberger C, Soper DM, Ziegler SF, Bluestone JA. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ Treg cells. J Exp Med 2006; 203: 1700-1711. http://dx.doi.org/10.1084/jem.20060772 PMid:16818678 PMCid:2118339
-
(2006)
J Exp Med
, vol.203
, pp. 1700-1711
-
-
Liu, W.1
Putnam, A.L.2
Xu-Yu, Z.3
Szot, G.L.4
Lee, M.R.5
Zhu, S.6
Gottlieb, P.A.7
Kapranov, P.8
Gingeras, T.R.9
Fazekas de St Groth, B.10
Clayberger, C.11
Soper, D.M.12
Ziegler, S.F.13
Bluestone, J.A.14
-
18
-
-
33645059454
-
Imbalance of regulatory cells in human autoimmune diseases
-
PMid:16476048 PMCid:1782226
-
Dejaco C, Duftner C, Grubeck-Loebenstein B, Schirmer M. Imbalance of regulatory cells in human autoimmune diseases. Immunology 2005; 117: 289-300. http://dx.doi.org/10.1111/j.1365-2567.2005.02317.x PMid:16476048 PMCid:1782226
-
(2005)
Immunology
, vol.117
, pp. 289-300
-
-
Dejaco, C.1
Duftner, C.2
Grubeck-Loebenstein, B.3
Schirmer, M.4
-
19
-
-
11244353393
-
Applying a new generation of genetic maps to understand human inflammatory disease
-
PMid:15630431
-
Hafler DA, de Jager PL. Applying a new generation of genetic maps to understand human inflammatory disease. Nat Rev Immunol 2005; 5: 83-91. http://dx.doi.org/10.1038/nri1532 PMid:15630431
-
(2005)
Nat Rev Immunol
, vol.5
, pp. 83-91
-
-
Hafler, D.A.1
de Jager, P.L.2
-
20
-
-
33746342994
-
Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease
-
PMid:16903903
-
Sakaguchi S, Ono M, Setoguchi R, Yagi H, Hori S, Fehervari Z, Shimizu J, Takahashi T, Nomura T. Foxp3+ CD25+ CD4+ natural regulatory T cells in dominant self-tolerance and autoimmune disease. Immunol Rev 2006; 212: 8-27. http://dx.doi.org/10.1111/j.0105-2896.2006.00427.x PMid:16903903
-
(2006)
Immunol Rev
, vol.212
, pp. 8-27
-
-
Sakaguchi, S.1
Ono, M.2
Setoguchi, R.3
Yagi, H.4
Hori, S.5
Fehervari, Z.6
Shimizu, J.7
Takahashi, T.8
Nomura, T.9
-
21
-
-
0026178213
-
X-linked lymphoreticular disease in the scurfy (sf) mutant mouse
-
PMid:2053595 PMCid:1886400
-
Godfrey VL, Wilkinson JE, Russell LB. X-linked lymphoreticular disease in the scurfy (sf) mutant mouse. Am J Pathol 1991; 138: 1379-1387. PMid:2053595 PMCid:1886400
-
(1991)
Am J Pathol
, vol.138
, pp. 1379-1387
-
-
Godfrey, V.L.1
Wilkinson, J.E.2
Russell, L.B.3
-
22
-
-
1842732224
-
Loss of cunctional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
-
PMid:15067033 PMCid:2211881
-
Viglietta V, Baecher-Allan C, Weiner HL, Hfler DA. Loss of cunctional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 2004; 199: 971-979. http://dx.doi.org/10.1084/jem.20031579 PMid:15067033 PMCid:2211881
-
(2004)
J Exp Med
, vol.199
, pp. 971-979
-
-
Viglietta, V.1
Baecher-Allan, C.2
Weiner, H.L.3
Hfler, D.A.4
-
23
-
-
23744515175
-
Decreased FOXP3 in multiple sclerosis patients
-
PMid:15952173
-
Huan J, Culbertson N, Spencer L, Bartholomew R, Burrows GG, Chou YK, Bourdette D, Ziegler SF, Offner H, Vandenbark AA. Decreased FOXP3 in multiple sclerosis patients. J Neurosci Res 2005; 81: 45-52. http://dx.doi.org/10.1002/jnr.20522 PMid:15952173
-
(2005)
J Neurosci Res
, vol.81
, pp. 45-52
-
-
Huan, J.1
Culbertson, N.2
Spencer, L.3
Bartholomew, R.4
Burrows, G.G.5
Chou, Y.K.6
Bourdette, D.7
Ziegler, S.F.8
Offner, H.9
Vandenbark, A.A.10
-
24
-
-
2442628376
-
Defective suppressor function of human CD4+CD25+ regulatory T cells in autoimmune polygranular T cells in autoimmunepolygrandular syndrome type II
-
PMid:15117972 PMCid:2211900
-
Kriegel MA, Lohamann T, Gabler C, Blank N, Kalden JR, Lorenz HM. Defective suppressor function of human CD4+CD25+ regulatory T cells in autoimmune polygranular T cells in autoimmunepolygrandular syndrome type II. J Exp Med 2004; 199: 1285-1891. http://dx.doi.org/10.1084/jem.20032158 PMid:15117972 PMCid:2211900
-
(2004)
J Exp Med
, vol.199
, pp. 1285-1891
-
-
Kriegel, M.A.1
Lohamann, T.2
Gabler, C.3
Blank, N.4
Kalden, J.R.5
Lorenz, H.M.6
-
25
-
-
11244291391
-
Functional defect of regulator CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis
-
PMid:15454488 PMCid:1847365
-
Balandina A, Lecart S, Dartevelle P, Saoudi A, Berrih-Aknin S. Functional defect of regulator CD4(+)CD25+ T cells in the thymus of patients with autoimmune myasthenia gravis. Blood 2005; 105: 735-41. http://dx.doi.org/10.1182/blood-2003-11-3900 PMid:15454488 PMCid:1847365
-
(2005)
Blood
, vol.105
, pp. 735-41
-
-
Balandina, A.1
Lecart, S.2
Dartevelle, P.3
Saoudi, A.4
Berrih-Aknin, S.5
-
26
-
-
33645776461
-
Control of autoimmune myocarditis and multi-organ inflammation by GITRhigh FoxP3- expressing CD25+ and CD25- regulatory T cells
-
PMid:16585568
-
Ono M, Shimizu J, Miyachi Y, Sakaguchi S. Control of autoimmune myocarditis and multi-organ inflammation by GITRhigh FoxP3- expressing CD25+ and CD25- regulatory T cells. J Immunol 2006; 176: 4748-4756. PMid:16585568
-
(2006)
J Immunol
, vol.176
, pp. 4748-4756
-
-
Ono, M.1
Shimizu, J.2
Miyachi, Y.3
Sakaguchi, S.4
-
27
-
-
0029414785
-
Interleukin-2 deficient mice: a new model to study autoimmunity and self-tolerance
-
PMid:8825281
-
Horak I, Lohler J, Ma A, Smith KA. Interleukin-2 deficient mice: a new model to study autoimmunity and self-tolerance. Immunol Rev 1995; 148: 35-44. http://dx.doi.org/10.1111/j.1600-065X.1995.tb00092.x PMid:8825281
-
(1995)
Immunol Rev
, vol.148
, pp. 35-44
-
-
Horak, I.1
Lohler, J.2
Ma, A.3
Smith, K.A.4
-
28
-
-
34248598295
-
Selection of FoxP3 regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells
-
PMid:17322887
-
Aschenbrenner K, D'Cruz LH, Vollmann EH, Hintenberger M, Emmerich J, Swee LK, Rolink A, Klein L. Selection of FoxP3 regulatory T cells specific for self antigen expressed and presented by Aire+ medullary thymic epithelial cells. Nature Immunol 2007; 8: 351-358. http://dx.doi.org/10.1038/ni1444 PMid:17322887
-
(2007)
Nature Immunol
, vol.8
, pp. 351-358
-
-
Aschenbrenner, K.1
D'Cruz, L.H.2
Vollmann, E.H.3
Hintenberger, M.4
Emmerich, J.5
Swee, L.K.6
Rolink, A.7
Klein, L.8
-
29
-
-
2942672441
-
Cornerstone of peripheral tolerance: naturally occurring CD4+CD24+ regulatory T cells
-
PMid:15207505
-
Piccirillo CA, Thornton AM. Cornerstone of peripheral tolerance: naturally occurring CD4+CD24+ regulatory T cells. Trends Immunol 2004; 25: 374-380. http://dx.doi.org/10.1016/j.it.2004.04.009 PMid:15207505
-
(2004)
Trends Immunol
, vol.25
, pp. 374-380
-
-
Piccirillo, C.A.1
Thornton, A.M.2
-
30
-
-
70049095101
-
How do regulatory T cells work?
-
PMid:19751267 PMCid:2784904
-
Corthay A. How do regulatory T cells work? Scand J Immunol 2009; 70: 326-336. http://dx.doi.org/10.1111/j.1365-3083.2009.02308.x PMid:19751267 PMCid:2784904
-
(2009)
Scand J Immunol
, vol.70
, pp. 326-336
-
-
Corthay, A.1
-
31
-
-
70349512606
-
Regulatory T cells: how do they suppress immune responses?
-
PMid:19737784
-
Sakaguchi S, Wing K, Onishi Y, Prieto-Martin P, Yamaguchi T. Regulatory T cells: how do they suppress immune responses? Int Immunol 2009; 21: 1105-1111. http://dx.doi.org/10.1093/intimm/dxp095 PMid:19737784
-
(2009)
Int Immunol
, vol.21
, pp. 1105-1111
-
-
Sakaguchi, S.1
Wing, K.2
Onishi, Y.3
Prieto-Martin, P.4
Yamaguchi, T.5
-
32
-
-
0031821875
-
CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production
-
PMid:9670041 PMCid:2212461
-
Thornton AM, Shevac EM. CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production. J Exp Med 1998; 188: 287-296. http://dx.doi.org/10.1084/jem.188.2.287 PMid:9670041 PMCid:2212461
-
(1998)
J Exp Med
, vol.188
, pp. 287-296
-
-
Thornton, A.M.1
Shevac, E.M.2
-
33
-
-
0031647622
-
Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state
-
PMid:9885918
-
Takahashi T, Kuniyasu Y, Toda M, Sakaguchi N, Itoh M, Iwata M, Shimizu J, Jakaguchi J. Immunologic self-tolerance maintained by CD25+CD4+ naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state. Int Immunol 1998; 10: 1969-1980. http://dx.doi.org/10.1093/intimm/10.12.1969 PMid:9885918
-
(1998)
Int Immunol
, vol.10
, pp. 1969-1980
-
-
Takahashi, T.1
Kuniyasu, Y.2
Toda, M.3
Sakaguchi, N.4
Itoh, M.5
Iwata, M.6
Shimizu, J.7
Jakaguchi, J.8
-
34
-
-
0032522488
-
CTLA-4 regulates tolerance induction and T cell differentiation in vivo
-
PMid:9558090
-
Walunas TL, Bluestone JA. CTLA-4 regulates tolerance induction and T cell differentiation in vivo. J Immunol 1998; 160: 3855-3860. PMid:9558090
-
(1998)
J Immunol
, vol.160
, pp. 3855-3860
-
-
Walunas, T.L.1
Bluestone, J.A.2
-
35
-
-
0036170938
-
Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance
-
PMid:11812990
-
Shimuzu J, Yamazaki S, Takahashi T, Ishida Y, Sakaguchi S. Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance. Nat Immunol 2002; 3: 135-142. http://dx.doi.org/10.1038/ni759 PMid:11812990
-
(2002)
Nat Immunol
, vol.3
, pp. 135-142
-
-
Shimuzu, J.1
Yamazaki, S.2
Takahashi, T.3
Ishida, Y.4
Sakaguchi, S.5
-
36
-
-
34250351459
-
Adenosine generations catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
-
PMid:17502665 PMCid:2118603
-
Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden K, Oukka M, Kuchroo VK, Strom TB, Robson SC. Adenosine generations catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 2007; 204: 1257-1265. http://dx.doi.org/10.1084/jem.20062512 PMid:17502665 PMCid:2118603
-
(2007)
J Exp Med
, vol.204
, pp. 1257-1265
-
-
Deaglio, S.1
Dwyer, K.M.2
Gao, W.3
Friedman, D.4
Usheva, A.5
Erat, A.6
Chen, J.F.7
Enjyoji, K.8
Linden, K.9
Oukka, M.10
Kuchroo, V.K.11
Strom, T.B.12
Robson, S.C.13
-
37
-
-
0033561648
-
TGF-beta 1 prevents the noncognate maturation of human dendritic Langherans cells
-
PMid:10201996
-
Geissmann F, Revy P, Regnault A, Lepelletier Y, Dy M, Brousse N, Amigorena S, Hermine O, Durandy A. TGF-beta 1 prevents the noncognate maturation of human dendritic Langherans cells. J Immunol 1999; 162: 4567-4575. PMid:10201996
-
(1999)
J Immunol
, vol.162
, pp. 4567-4575
-
-
Geissmann, F.1
Revy, P.2
Regnault, A.3
Lepelletier, Y.4
Dy, M.5
Brousse, N.6
Amigorena, S.7
Hermine, O.8
Durandy, A.9
-
38
-
-
0033233252
-
TGF-β1 regulation of dendritic cells
-
Strobl H, Knapp W. TGF-β1 regulation of dendritic cells. Microbes Infection 1999; 1: 1283-1290. http://dx.doi.org/10.1016/S1286-4579(99)00256-7
-
(1999)
Microbes Infection
, vol.1
, pp. 1283-1290
-
-
Strobl, H.1
Knapp, W.2
-
39
-
-
0036597371
-
CD4+CD25+ suppressor T cells: more questions than answers
-
PMid:12093005
-
Shevac EM. CD4+CD25+ suppressor T cells: more questions than answers. Nat Rev Immunol 2002; 2: 389-400. PMid:12093005
-
(2002)
Nat Rev Immunol
, vol.2
, pp. 389-400
-
-
Shevac, E.M.1
-
40
-
-
33645023639
-
Mechanisms of immune suppression by interleukin-10 and transforming growth factor-β: the role of T regulatory cells
-
Taylor A, Vehagen J, Blaser K, Akdis M, Akdis CA. Mechanisms of immune suppression by interleukin-10 and transforming growth factor-β: the role of T regulatory cells. Immunol 2006; 117: 443-442.
-
(2006)
Immunol
, vol.117
, pp. 443-442
-
-
Taylor, A.1
Vehagen, J.2
Blaser, K.3
Akdis, M.4
Akdis, C.A.5
-
41
-
-
0036886390
-
The role of IL-10 and TGF-β in the differentiation and effector function of T regulatory cells
-
PMid:12483031
-
Levings MK, Bacchetta R, Schulz U, Roncarolo MG. The role of IL-10 and TGF-β in the differentiation and effector function of T regulatory cells. Int Arch Allergy Immunol 2002; 129: 263-276. http://dx.doi.org/10.1159/000067596 PMid:12483031
-
(2002)
Int Arch Allergy Immunol
, vol.129
, pp. 263-276
-
-
Levings, M.K.1
Bacchetta, R.2
Schulz, U.3
Roncarolo, M.G.4
-
42
-
-
5644302161
-
Human T regulatory cells can use the perforin pathway to cause autologous target cell death
-
PMid:15485635
-
Grossman WJ, Verbsky JW, Barchet W, Colonna M, Atkinson JP, Ley TJ. Human T regulatory cells can use the perforin pathway to cause autologous target cell death. Immunity 2004; 21: 589-601. http://dx.doi.org/10.1016/j.immuni.2004.09.002 PMid:15485635
-
(2004)
Immunity
, vol.21
, pp. 589-601
-
-
Grossman, W.J.1
Verbsky, J.W.2
Barchet, W.3
Colonna, M.4
Atkinson, J.P.5
Ley, T.J.6
-
43
-
-
5644238762
-
Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells
-
PMid:15238416
-
Grossman WJ, Verbsky JW, Tollefsen BL, Kemper C, Atkinson JP, Levy TJ. Differential expression of granzymes A and B in human cytotoxic lymphocyte subsets and T regulatory cells. Blood 2004; 104: 2840-2848. http://dx.doi.org/10.1182/blood-2004-03-0859 PMid:15238416
-
(2004)
Blood
, vol.104
, pp. 2840-2848
-
-
Grossman, W.J.1
Verbsky, J.W.2
Tollefsen, B.L.3
Kemper, C.4
Atkinson, J.P.5
Levy, T.J.6
-
44
-
-
13844307760
-
Chronic lymphocytic leukemia
-
PMid:15728813
-
Chiorazzi N, Rai KR, Ferrarini M. Chronic lymphocytic leukemia. N Engl J Med 2005; 352: 804-815. http://dx.doi.org/10.1056/NEJMra041720 PMid:15728813
-
(2005)
N Engl J Med
, vol.352
, pp. 804-815
-
-
Chiorazzi, N.1
Rai, K.R.2
Ferrarini, M.3
-
45
-
-
0037348740
-
Abnormal T-cell function in B-cell chronic lymphocytic leukaemia
-
Scrivener S, Goddard RV, Kaminski ER, Prentice AG. Abnormal T-cell function in B-cell chronic lymphocytic leukaemia. Leuk Lymphoma 2003; 44: 383-389. http://dx.doi.org/10.1080/1042819021000029993
-
(2003)
Leuk Lymphoma
, vol.44
, pp. 383-389
-
-
Scrivener, S.1
Goddard, R.V.2
Kaminski, E.R.3
Prentice, A.G.4
-
46
-
-
79953814653
-
Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL
-
PMid:21270444
-
Christopoulos P, Pfeifer D, Bartholome K, Follo M, Timmer J, Fisch P, Veelken H. Definition and characterization of the systemic T-cell dysregulation in untreated indolent B-cell lymphoma and very early CLL. Blood 2011; 117: 3836-3846. http://dx.doi.org/10.1182/blood-2010-07-299321 PMid:21270444
-
(2011)
Blood
, vol.117
, pp. 3836-3846
-
-
Christopoulos, P.1
Pfeifer, D.2
Bartholome, K.3
Follo, M.4
Timmer, J.5
Fisch, P.6
Veelken, H.7
-
47
-
-
24744432528
-
Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine
-
PMid:15914560
-
Beyer M, Kochanek M, Darabi K, Popov A, Jensen M, Endl E, Knolle PA, Thomas RK, von Bergwelt-Baildon M, Debey S, Hallek M, Schultze JL. Reduced frequencies and suppressive function of CD4+CD25hi regulatory T cells in patients with chronic lymphocytic leukemia after therapy with fludarabine. Blood 2005; 106: 2018-2025. http://dx.doi.org/10.1182/blood-2005-02-0642 PMid:15914560
-
(2005)
Blood
, vol.106
, pp. 2018-2025
-
-
Beyer, M.1
Kochanek, M.2
Darabi, K.3
Popov, A.4
Jensen, M.5
Endl, E.6
Knolle, P.A.7
Thomas, R.K.8
von Bergwelt-Baildon, M.9
Debey, S.10
Hallek, M.11
Schultze, J.L.12
-
48
-
-
54549110000
-
Characterization of regulatory T cells in patients with B-cell chronic lymphocytic leukemia
-
PMid:18695923
-
Giannopoulos K, Schmitt M, Kowal M, Wlasiuk P, Bojarska-Junak A, Chen J, Rolinski J, Dmoszynska A. Characterization of regulatory T cells in patients with B-cell chronic lymphocytic leukemia. Oncol Rep 2008; 20: 677-682. PMid:18695923
-
(2008)
Oncol Rep
, vol.20
, pp. 677-682
-
-
Giannopoulos, K.1
Schmitt, M.2
Kowal, M.3
Wlasiuk, P.4
Bojarska-Junak, A.5
Chen, J.6
Rolinski, J.7
Dmoszynska, A.8
-
49
-
-
68449083231
-
Expansion of regulatory T cells in B chronic lymphocytic leukemia: enhanced 'brakes' on host immunity
-
Deutsch V, Pierry C, Polliack A. Expansion of regulatory T cells in B chronic lymphocytic leukemia: enhanced 'brakes' on host immunity. Leuk Lymphoma 2009; 50: 687-688. http://dx.doi.org/10.1080/10428190902954389
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 687-688
-
-
Deutsch, V.1
Pierry, C.2
Polliack, A.3
-
50
-
-
68449093742
-
Enhanced formation and survival of CD4+CD25highFoxP3+ T-cells in chronic lymphocytic leukemia
-
Jak M, Mous R, Remmerswaal EBM, Spijker R, Jaspers A, Yague A, Eldering E, van Lier RAW, Van Oers MHJ. Enhanced formation and survival of CD4+CD25highFoxP3+ T-cells in chronic lymphocytic leukemia. Leuk Lymphoma 2009; 50: 788-801. http://dx.doi.org/10.1080/10428190902803677
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 788-801
-
-
Jak, M.1
Mous, R.2
Remmerswaal, E.B.M.3
Spijker, R.4
Jaspers, A.5
Yague, A.6
Eldering, E.7
van Lier, R.A.W.8
Van Oers, M.H.J.9
-
51
-
-
79952100710
-
Regulatory T-cell number is increate in chronic lymphocytic leukemia patients and correlate with progressive disease
-
PMid:20880586
-
D'Arena G, Laurenti L, Minervini MM, Deaglio S, Bonello L, De Martino L, De Padua L, Savino L, Tarnani M, De Feo V, Cascavilla N. Regulatory T-cell number is increate in chronic lymphocytic leukemia patients and correlate with progressive disease. Leuk Res 2011; 35: 363-368. http://dx.doi.org/10.1016/j.leukres.2010.08.010 PMid:20880586
-
(2011)
Leuk Res
, vol.35
, pp. 363-368
-
-
D'Arena, G.1
Laurenti, L.2
Minervini, M.M.3
Deaglio, S.4
Bonello, L.5
De Martino, L.6
De Padua, L.7
Savino, L.8
Tarnani, M.9
De Feo, V.10
Cascavilla, N.11
-
52
-
-
38349075755
-
The high frequency of T regulatory cells in patients with B-cell chronic lymphocytic leukemia is diminished through treatment with thalidomide
-
PMid:17657216
-
Giannopoulos K, Schmitt M, Wlasiuk P, Chen J, Bojarska-Junak A, Kowal M, Rolinski J, Dmoszynska A. The high frequency of T regulatory cells in patients with B-cell chronic lymphocytic leukemia is diminished through treatment with thalidomide. Leukemia 2008; 22: 222-224. http://dx.doi.org/10.1038/sj.leu.2404869 PMid:17657216
-
(2008)
Leukemia
, vol.22
, pp. 222-224
-
-
Giannopoulos, K.1
Schmitt, M.2
Wlasiuk, P.3
Chen, J.4
Bojarska-Junak, A.5
Kowal, M.6
Rolinski, J.7
Dmoszynska, A.8
-
53
-
-
33646370647
-
TNF downmodulates the function of human CD4+CD25hi T-regulatory cells
-
PMid:16537805 PMCid:1895836
-
Valencia X, Stephens G, Goldbach-Mansky R, Wilson M, Shevach EM, Lipsky PE. TNF downmodulates the function of human CD4+CD25hi T-regulatory cells. Blood 2006; 108: 253-261. http://dx.doi.org/10.1182/blood-2005-11-4567 PMid:16537805 PMCid:1895836
-
(2006)
Blood
, vol.108
, pp. 253-261
-
-
Valencia, X.1
Stephens, G.2
Goldbach-Mansky, R.3
Wilson, M.4
Shevach, E.M.5
Lipsky, P.E.6
-
54
-
-
70349153856
-
Immune dysfunction in chronic lymphocytic leukemia T cells and Lenalidomide as an immunodulatory drug
-
PMid:19734414 PMCid:2738710
-
Ramsay AG, Gribben JG. Immune dysfunction in chronic lymphocytic leukemia T cells and Lenalidomide as an immunodulatory drug. Haematologica 2009; 94: 1198-1202. http://dx.doi.org/10.3324/haematol.2009.009274 PMid:19734414 PMCid:2738710
-
(2009)
Haematologica
, vol.94
, pp. 1198-1202
-
-
Ramsay, A.G.1
Gribben, J.G.2
-
55
-
-
80051928145
-
Treatment with Lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia
-
PMid:21858802
-
Lee B-N, Gao H, Cohen EN, Badoux X, Wierda WG, Estrov Z, Faderl SH, Keating MJ, Ferrajoli A, Reuben JM. Treatment with Lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia. Cancer 2011; 117: 3999-4008. http://dx.doi.org/10.1002/cncr.25983 PMid:21858802
-
(2011)
Cancer
, vol.117
, pp. 3999-4008
-
-
Lee, B.-N.1
Gao, H.2
Cohen, E.N.3
Badoux, X.4
Wierda, W.G.5
Estrov, Z.6
Faderl, S.H.7
Keating, M.J.8
Ferrajoli, A.9
Reuben, J.M.10
-
56
-
-
79955500329
-
egulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia
-
PMid:21523729
-
Weiss L, Melchardt T, Egle A, Grabmer C, Greil R, Tinhofer I.Regulatory T cells predict the time to initial treatment in early stage chronic lymphocytic leukemia. Cancer 2011; 117: 2163-2169. http://dx.doi.org/10.1002/cncr.25752 PMid:21523729
-
(2011)
Cancer
, vol.117
, pp. 2163-2169
-
-
Weiss, L.1
Melchardt, T.2
Egle, A.3
Grabmer, C.4
Greil, R.5
Tinhofer, I.6
-
57
-
-
84861348588
-
A shorter time to the first treatment may be predicted by the absolute number of regulatory T-cells in patients with Rai stage 0 chronic lymphocytic leukemia
-
PMid:22460620
-
D'Arena G, D'Auria F, Simeon V, Laurenti L, Deaglio S, Mansueto G, Del Principe MI, Statuto T, Pietrantuono G, Guariglia R, Innocenti I, Martorelli MC, Villani O, De Feo V, Del Poeta G, Musto P. A shorter time to the first treatment may be predicted by the absolute number of regulatory T-cells in patients with Rai stage 0 chronic lymphocytic leukemia. Am J Hematol 2012; 87; 628-631. http://dx.doi.org/10.1002/ajh.23170 PMid:22460620
-
(2012)
Am J Hematol
, vol.87
, pp. 628-631
-
-
D'Arena, G.1
D'Auria, F.2
Simeon, V.3
Laurenti, L.4
Deaglio, S.5
Mansueto, G.6
Del Principe, M.I.7
Statuto, T.8
Pietrantuono, G.9
Guariglia, R.10
Innocenti, I.11
Martorelli, M.C.12
Villani, O.13
De Feo, V.14
Del Poeta, G.15
Musto, P.16
-
58
-
-
45149100665
-
Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute - Working Group 1996 Guidelines
-
PMid:18216293 PMCid:2972576
-
Hallek M, Cheson BD, Catovsky D, Caligaris-Cappio F, Dighiero G, Döhner H, Hillmen P, Keating MJ, Montserrat E, Rai KR, Kipps JK. Guidelines for the diagnosis and treatment of chronic lymphocytic leukemia: a report from the International Workshop on Chronic Lymphocytic Leukemia updating the National Cancer Institute - Working Group 1996 Guidelines. Blood 2008; 111: 5446-5456. http://dx.doi.org/10.1182/blood-2007-06-093906 PMid:18216293 PMCid:2972576
-
(2008)
Blood
, vol.111
, pp. 5446-5456
-
-
Hallek, M.1
Cheson, B.D.2
Catovsky, D.3
Caligaris-Cappio, F.4
Dighiero, G.5
Döhner, H.6
Hillmen, P.7
Keating, M.J.8
Montserrat, E.9
Rai, K.R.10
Kipps, J.K.11
-
59
-
-
84856577660
-
Circulating regulatory T cells in "clinical" monoclonal B-cell lymphocytosis
-
PMid:22230398
-
D'Arena G, Rossi G, Minervini MM, Savino L, D'Auria F, Laurenti L, Del Principe MI, Deaglio S, Biagi A, De Martino L, De Feo V, Cascavilla N, Musto P, Del Poeta G. Circulating regulatory T cells in "clinical" monoclonal B-cell lymphocytosis. Int J Immunopathol Pharmacol 2011; 24: 915-923. PMid:22230398
-
(2011)
Int J Immunopathol Pharmacol
, vol.24
, pp. 915-923
-
-
D'Arena, G.1
Rossi, G.2
Minervini, M.M.3
Savino, L.4
D'Auria, F.5
Laurenti, L.6
Del Principe, M.I.7
Deaglio, S.8
Biagi, A.9
De Martino, L.10
De Feo, V.11
Cascavilla, N.12
Musto, P.13
Del Poeta, G.14
-
60
-
-
27644433355
-
Role of regulatory T cells in human disease
-
PMid:16275360
-
Chatila TA. Role of regulatory T cells in human disease. J Allergy Clin Immunol 2005; 116: 949-959. http://dx.doi.org/10.1016/j.jaci.2005.08.047 PMid:16275360
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 949-959
-
-
Chatila, T.A.1
-
61
-
-
35548950221
-
Regulatory T-cell inhibition versus depletion: the right choice in cancer immunotherapy
-
PMid:17957190
-
Colombo MP, Piconese S. Regulatory T-cell inhibition versus depletion: the right choice in cancer immunotherapy. Nature Rev 2007; 7: 880-887. http://dx.doi.org/10.1038/nrc2250 PMid:17957190
-
(2007)
Nature Rev
, vol.7
, pp. 880-887
-
-
Colombo, M.P.1
Piconese, S.2
-
62
-
-
47249124078
-
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
-
PMid:18613848
-
Brusko TM, Putnam AL, Bluestone JA. Human regulatory T cells: role in autoimmune disease and therapeutic opportunities. Immunol Rev 2008; 223: 371388. http://dx.doi.org/10.1111/j.1600-065X.2008.00637.x PMid:18613848
-
(2008)
Immunol Rev
, vol.223
, pp. 371388
-
-
Brusko, T.M.1
Putnam, A.L.2
Bluestone, J.A.3
-
63
-
-
67349239049
-
T-regulatory cell modulation: the future of cancer immunotherapy?
-
PMid:19384299 PMCid:2695683
-
Nizar S, Copier J, Meyer B, Bodman-Smith M, Galustian C, Kumar D, Dalgleish A. T-regulatory cell modulation: the future of cancer immunotherapy? Br J Caner 2009; 100: 1697-1703. http://dx.doi.org/10.1038/sj.bjc.6605040 PMid:19384299 PMCid:2695683
-
(2009)
Br J Caner
, vol.100
, pp. 1697-1703
-
-
Nizar, S.1
Copier, J.2
Meyer, B.3
Bodman-Smith, M.4
Galustian, C.5
Kumar, D.6
Dalgleish, A.7
-
64
-
-
79959470409
-
Targeting regulatory t cells for anticancer therapy
-
PMid:21561409
-
D'Arena G, Deaglio S, Laurenti L, De Martino L, De Feo V, Fusco BM, Carella AM, Cascavilla N, Musto P. Targeting regulatory t cells for anticancer therapy. Mini-Rev Med Chem 2011; 11: 480-485. http://dx.doi.org/10.2174/138955711795843365 PMid:21561409
-
(2011)
Mini-Rev Med Chem
, vol.11
, pp. 480-485
-
-
D'Arena, G.1
Deaglio, S.2
Laurenti, L.3
De Martino, L.4
De Feo, V.5
Fusco, B.M.6
Carella, A.M.7
Cascavilla, N.8
Musto, P.9
-
65
-
-
79953114328
-
Regulatory T-cell adoptive immunotherapy: potential for treatment of autoimmunity
-
PMid:21426259
-
Wright GP, Ehrenstein MR, Stauss HJ. Regulatory T-cell adoptive immunotherapy: potential for treatment of autoimmunity. Expert Rev Clin Immunol 2011; 7: 213-225. http://dx.doi.org/10.1586/eci.10.96 PMid:2142625
-
(2011)
Expert Rev Clin Immunol
, vol.7
, pp. 213-225
-
-
Wright, G.P.1
Ehrenstein, M.R.2
Stauss, H.J.3
|