메뉴 건너뛰기




Volumn 117, Issue 17, 2011, Pages 3999-4008

Treatment with lenalidomide modulates T-cell immunophenotype and cytokine production in patients with chronic lymphocytic leukemia

Author keywords

chronic lymphocytic leukemia; cytokines; immunomodulatory agents; T cells

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 2; LENALIDOMIDE; T LYMPHOCYTE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 80051928145     PISSN: 0008543X     EISSN: 10970142     Source Type: Journal    
DOI: 10.1002/cncr.25983     Document Type: Article
Times cited : (73)

References (33)
  • 2
    • 33750607347 scopus 로고    scopus 로고
    • A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma
    • Richardson PG, Blood E, Mitsiades CS, et al. A randomized phase 2 study of lenalidomide therapy for patients with relapsed or relapsed and refractory multiple myeloma. Blood 2006; 108: 3458-3464.
    • (2006) Blood , vol.108 , pp. 3458-3464
    • Richardson, P.G.1    Blood, E.2    Mitsiades, C.S.3
  • 3
    • 34547106018 scopus 로고    scopus 로고
    • Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
    • DOI 10.1038/nrc2189, PII NRC2189
    • Hideshima T, Mitsiades C, Tonon G, Richardson PG, Anderson KC,. Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets. Nat Rev Cancer. 2007; 7: 585-598. (Pubitemid 47106630)
    • (2007) Nature Reviews Cancer , vol.7 , Issue.8 , pp. 585-598
    • Hideshima, T.1    Mitsiades, C.2    Tonon, G.3    Richardson, P.G.4    Anderson, K.C.5
  • 5
    • 69949096727 scopus 로고    scopus 로고
    • Mechanism of action of lenalidomide in hematological malignancies
    • Kotla V, Goel S, Nischal S, et al. Mechanism of action of lenalidomide in hematological malignancies. J Hematol Oncol. 2009; 12: 36-46.
    • (2009) J Hematol Oncol , vol.12 , pp. 36-46
    • Kotla, V.1    Goel, S.2    Nischal, S.3
  • 6
    • 78649373387 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia
    • Hallek M, Pflug N,. Chronic lymphocytic leukemia. Ann Oncol. 2010; 21 (suppl 7): vii154-vii164.
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 7
    • Hallek, M.1    Pflug, N.2
  • 7
    • 77955436262 scopus 로고    scopus 로고
    • Immunomodulators in chronic lymphocytic leukemia: Where does lenalidomide belong?
    • Brown JR,. Immunomodulators in chronic lymphocytic leukemia: where does lenalidomide belong? Leuk Lymphoma. 2010; 51: 1382-1385.
    • (2010) Leuk Lymphoma , vol.51 , pp. 1382-1385
    • Brown, J.R.1
  • 8
    • 77957317687 scopus 로고    scopus 로고
    • Lenalidomide: A synthetic compound with an evolving role in cancer management
    • Saloura V, Grivas PD,. Lenalidomide: a synthetic compound with an evolving role in cancer management. Hematology. 2010; 15: 318-331.
    • (2010) Hematology , vol.15 , pp. 318-331
    • Saloura, V.1    Grivas, P.D.2
  • 9
    • 76149124676 scopus 로고    scopus 로고
    • Combination therapy with lenalidomide and rituximab in patients with relapsed chronic lymphocytic leukemia(CLL)
    • [abstract]. Abstract 206
    • Ferrajoli A, Badoux XC, O'Brien S, et al. Combination therapy with lenalidomide and rituximab in patients with relapsed chronic lymphocytic leukemia(CLL) [abstract]. Blood. 2009; 114 (suppl 1): 89. Abstract 206.
    • (2009) Blood , vol.114 , Issue.SUPPL. 1 , pp. 89
    • Ferrajoli, A.1    Badoux, X.C.2    O'Brien, S.3
  • 10
    • 78149466993 scopus 로고    scopus 로고
    • A phase i study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL
    • Brown JR, Abramson J, Hochberg E, et al. A phase I study of lenalidomide in combination with fludarabine and rituximab in previously untreated CLL/SLL. Leukemia. 2010; 24: 1972-1975.
    • (2010) Leukemia , vol.24 , pp. 1972-1975
    • Brown, J.R.1    Abramson, J.2    Hochberg, E.3
  • 11
    • 77950966887 scopus 로고    scopus 로고
    • Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway
    • Lapalombella R, Andritsos L, Liu Q, et al. Lenalidomide treatment promotes CD154 expression on CLL cells and enhances production of antibodies by normal B cells through a PI3-kinase-dependent pathway. Blood. 2010; 115: 2619-2629.
    • (2010) Blood , vol.115 , pp. 2619-2629
    • Lapalombella, R.1    Andritsos, L.2    Liu, Q.3
  • 12
    • 65549151712 scopus 로고    scopus 로고
    • E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction
    • Gorgun G, Ramsay AG, Holderried TA, et al. E(mu)-TCL1 mice represent a model for immunotherapeutic reversal of chronic lymphocytic leukemia-induced T-cell dysfunction. Proc Natl Acad Sci U S A. 2009; 106: 6250-6255.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 6250-6255
    • Gorgun, G.1    Ramsay, A.G.2    Holderried, T.A.3
  • 13
    • 69549116054 scopus 로고    scopus 로고
    • Synergistic antitumor effects of lenalidomide and rituximab on mantle cell lymphoma in vitro and in vivo
    • Zhang L, Qian Z, Cai Z, et al. Synergistic antitumor effects of lenalidomide and rituximab on mantle cell lymphoma in vitro and in vivo. Am J Hematol. 2009; 84: 553-559.
    • (2009) Am J Hematol , vol.84 , pp. 553-559
    • Zhang, L.1    Qian, Z.2    Cai, Z.3
  • 15
    • 0029981025 scopus 로고    scopus 로고
    • National Cancer Institute-sponsored Working Group guidelines for chronic lymphocytic leukemia: Revised guidelines for diagnosis and treatment
    • Cheson BD, Bennett JM, Grever M, et al. National Cancer Institute-Sponsored Work Group guidelines for chronic lymphocytic leukemia: revised guidelines for diagnosis and treatment. Blood. 1996; 87: 4990-4997. (Pubitemid 26189840)
    • (1996) Blood , vol.87 , Issue.12 , pp. 4990-4997
    • Cheson, B.D.1    Bennett, J.M.2    Grever, M.3    Kay, N.4    Keating, M.J.5    O'Brien, S.6    Rai, K.R.7
  • 16
    • 0034108647 scopus 로고    scopus 로고
    • Restoration of Th1 cytokine synthesis by T cells of patients with chronic myelogenous leukemia in cytogenetic and hematologic remission with interferon-α
    • Reuben JM, Lee BN, Johnson H, Fritsche H, Kantarjian HM, Talpaz M,. Restoration of Th1 cytokine synthesis by T cells of patients with chronic myelogenous leukemia in cytogenetic and hematologic remission with interferon-alpha. Clin Cancer Res. 2000; 6: 1671-1677. (Pubitemid 30305059)
    • (2000) Clinical Cancer Research , vol.6 , Issue.5 , pp. 1671-1677
    • Reuben, J.M.1    Lee, B.-N.2    Johnson, H.3    Fritsche, H.4    Kantarjian, H.M.5    Talpaz, M.6
  • 17
    • 33847242598 scopus 로고    scopus 로고
    • Foxp3 occupancy and regulation of key target genes during T-cell stimulation
    • Marson A, Kretschmer K, Frampton GM, et al. Foxp3 occupancy and regulation of key target genes during T-cell stimulation. Nature. 2007; 445: 931-935.
    • (2007) Nature , vol.445 , pp. 931-935
    • Marson, A.1    Kretschmer, K.2    Frampton, G.M.3
  • 19
    • 0037348740 scopus 로고    scopus 로고
    • Abnormal T-cell function in B-cell chronic lymphocytic leukaemia
    • DOI 10.1080/1042819021000029993
    • Scrivener S, Goddard RV, Kaminski ER, Prentice AG,. Abnormal T-cell function in B-cell chronic lymphocytic leukaemia. Leuk Lymphoma. 2003; 44: 383-389. (Pubitemid 36118829)
    • (2003) Leukemia and Lymphoma , vol.44 , Issue.3 , pp. 383-389
    • Scrivener, S.1    Goddard, R.V.2    Kaminski, E.R.3    Prentice, A.G.4
  • 20
    • 68449093742 scopus 로고    scopus 로고
    • Enhanced formation and survival of CD4+ CD25hi Foxp3+ T-cells in chronic lymphocytic leukemia
    • Jak M, Mous R, Remmerswaal EB, et al. Enhanced formation and survival of CD4+ CD25hi Foxp3+ T-cells in chronic lymphocytic leukemia. Leuk Lymphoma. 2009; 50: 788-801.
    • (2009) Leuk Lymphoma , vol.50 , pp. 788-801
    • Jak, M.1    Mous, R.2    Remmerswaal, E.B.3
  • 21
    • 23844436988 scopus 로고    scopus 로고
    • Signaling molecules and cytokine production in T cells of patients with B-cell chronic lymphocytic leukemia (B-CLL): Comparison of indolent and progressive disease
    • DOI 10.1385/MO:22:3:291
    • Kiaii S, Choudhury A, Mozaffari F, Kimby E, Osterborg A, Mellstedt H,. Signaling molecules and cytokine production in T cells of patients with B-cell chronic lymphocytic leukemia (B-CLL): comparison of indolent and progressive disease. Med Oncol. 2005; 22: 291-302. (Pubitemid 41176325)
    • (2005) Medical Oncology , vol.22 , Issue.3 , pp. 291-302
    • Kiaii, S.1    Choudhury, A.2    Mozaffari, F.3    Kimby, E.4    Osterborg, A.5    Mellstedt, H.6
  • 22
  • 23
    • 0035160749 scopus 로고    scopus 로고
    • Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: Correlation with phenotypic characteristics and outcome
    • DOI 10.1182/blood.V97.1.256
    • Fayad L, Keating MJ, Reuben JM, et al. Interleukin-6 and interleukin-10 levels in chronic lymphocytic leukemia: correlation with phenotypic characteristics and outcome. Blood. 2001; 97: 256-263. (Pubitemid 32061268)
    • (2001) Blood , vol.97 , Issue.1 , pp. 256-263
    • Fayad, L.1    Keating, M.J.2    Reuben, J.M.3    O'Brien, S.4    Lee, B.-N.5    Lerner, S.6    Kurzrock, R.7
  • 25
    • 70349187442 scopus 로고    scopus 로고
    • Role of decreased production of interleukin-10 and interferon-gamma in spontaneous apoptosis of B-chronic lymphocytic leukemia lymphocytes in vitro
    • Djurdjevic P, Zelen I, Ristic P, Baskic D, Popovic S, Arsenijevic N,. Role of decreased production of interleukin-10 and interferon-gamma in spontaneous apoptosis of B-chronic lymphocytic leukemia lymphocytes in vitro. Arch Med Res. 2009; 40: 357-363.
    • (2009) Arch Med Res , vol.40 , pp. 357-363
    • Djurdjevic, P.1    Zelen, I.2    Ristic, P.3    Baskic, D.4    Popovic, S.5    Arsenijevic, N.6
  • 26
    • 0033136302 scopus 로고    scopus 로고
    • + naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance
    • Itoh M, Takahashi T, Sakaguchi N, et al. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance. J Immunol. 1999; 162: 5317-5326. (Pubitemid 29307138)
    • (1999) Journal of Immunology , vol.162 , Issue.9 , pp. 5317-5326
    • Itoh, M.1    Takahashi, T.2    Sakaguchi, N.3    Kuniyasu, Y.4    Shimizu, J.5    Otsuka, F.6    Sakaguchi, S.7
  • 29
    • 38349075755 scopus 로고    scopus 로고
    • The high frequency of T regulatory cells in patients with B-cell chronic lymphocytic leukemia is diminished through treatment with thalidomide
    • Giannopoulos K, Schmitt M, WÅasiuk P, et al. The high frequency of T regulatory cells in patients with B-cell chronic lymphocytic leukemia is diminished through treatment with thalidomide. Leukemia. 2008; 22: 222-224.
    • (2008) Leukemia , vol.22 , pp. 222-224
    • Giannopoulos, K.1    Schmitt, M.2    Wåasiuk, P.3
  • 30
    • 0020076308 scopus 로고
    • Autologous mixed lymphocyte reaction in lymphoid malignancies. Lack of correlation with disease activity or clinical remission
    • Quesada JR, Reuben JM, Scouros MA, Murphy SG,. Autologous mixed lymphocyte reaction in lymphoid malignancies. Lack of correlation with disease activity or clinical remission. Cancer Immunol Immunother. 1982; 12: 231-239. (Pubitemid 12105227)
    • (1982) Cancer Immunology, Immunotherapy , vol.12 , Issue.3 , pp. 231-239
    • Quesada, J.R.1    Reuben, J.M.2    Scouros, M.A.3    Murphy, S.G.4
  • 31
    • 45949100928 scopus 로고    scopus 로고
    • Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia
    • Ferrajoli A, Lee BN, Schlette EJ, et al. Lenalidomide induces complete and partial remissions in patients with relapsed and refractory chronic lymphocytic leukemia. Blood 2008; 111: 5291-5297.
    • (2008) Blood , vol.111 , pp. 5291-5297
    • Ferrajoli, A.1    Lee, B.N.2    Schlette, E.J.3
  • 32
    • 67349107194 scopus 로고    scopus 로고
    • The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
    • Galustian C, Meyer B, Labarthe MC, et al. The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells. Cancer Immunol Immunother. 2009; 58: 1033-1045.
    • (2009) Cancer Immunol Immunother , vol.58 , pp. 1033-1045
    • Galustian, C.1    Meyer, B.2    Labarthe, M.C.3
  • 33
    • 74949083498 scopus 로고    scopus 로고
    • Efficacy of lenalidomide in patients with chronic lymphocytic leukemia with high-risk cytogenetics
    • Sher T, Miller KC, Lawrence D, et al. Efficacy of lenalidomide in patients with chronic lymphocytic leukemia with high-risk cytogenetics. Leuk Lymphoma. 2010; 51: 85-88.
    • (2010) Leuk Lymphoma , vol.51 , pp. 85-88
    • Sher, T.1    Miller, K.C.2    Lawrence, D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.