-
1
-
-
34250760886
-
Small-molecule pheromones that control dauer development in Caenorhabditis elegans
-
Butcher RA, Fujita M, Schroeder FC, Clardy J (2007) Small-molecule pheromones that control dauer development in Caenorhabditis elegans. Nat Chem Biol 3(7):420-422.
-
(2007)
Nat Chem Biol
, vol.3
, Issue.7
, pp. 420-422
-
-
Butcher, R.A.1
Fujita, M.2
Schroeder, F.C.3
Clardy, J.4
-
2
-
-
13444251248
-
Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone
-
Jeong PY, et al. (2005) Chemical structure and biological activity of the Caenorhabditis elegans dauer-inducing pheromone. Nature 433(7025):541-545.
-
(2005)
Nature
, vol.433
, Issue.7025
, pp. 541-545
-
-
Jeong, P.Y.1
-
3
-
-
66049141674
-
A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans
-
Pungaliya C, et al. (2009) A shortcut to identifying small molecule signals that regulate behavior and development in Caenorhabditis elegans. Proc Natl Acad Sci USA 106(19):7708-7713.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.19
, pp. 7708-7713
-
-
Pungaliya, C.1
-
4
-
-
50649118316
-
A blend of small molecules regulates both mating and development in Caenorhabditis elegans
-
Srinivasan J, et al. (2008) A blend of small molecules regulates both mating and development in Caenorhabditis elegans. Nature 454(7208):1115-1118.
-
(2008)
Nature
, vol.454
, Issue.7208
, pp. 1115-1118
-
-
Srinivasan, J.1
-
5
-
-
84865258434
-
Targeted metabolomics reveals a male pheromone and sexspecific ascaroside biosynthesis in Caenorhabditis elegans
-
Izrayelit Y, et al. (2012) Targeted metabolomics reveals a male pheromone and sexspecific ascaroside biosynthesis in Caenorhabditis elegans. ACS Chem Biol 7(8): 1321-1325.
-
(2012)
ACS Chem Biol
, vol.7
, Issue.8
, pp. 1321-1325
-
-
Izrayelit, Y.1
-
6
-
-
84856475227
-
A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans
-
Srinivasan J, et al. (2012) A modular library of small molecule signals regulates social behaviors in Caenorhabditis elegans. PLoS Biol 10(1):e1001237.
-
(2012)
PLoS Biol
, vol.10
, Issue.1
-
-
Srinivasan, J.1
-
7
-
-
84856262927
-
Comparative metabolomics reveals biogenesis of ascarosides, a modular library of small-molecule signals in C. elegans
-
von Reuss SH, et al. (2012) Comparative metabolomics reveals biogenesis of ascarosides, a modular library of small-molecule signals in C. elegans. J Am Chem Soc 134(3): 1817-1824.
-
(2012)
J Am Chem Soc
, vol.134
, Issue.3
, pp. 1817-1824
-
-
Von Reuss, S.H.1
-
8
-
-
77957329120
-
Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans
-
Yamada K, et al. (2010) Olfactory plasticity is regulated by pheromonal signaling in Caenorhabditis elegans. Science 329(5999):1647-1650.
-
(2010)
Science
, vol.329
, Issue.5999
, pp. 1647-1650
-
-
Yamada, K.1
-
9
-
-
0021418719
-
The Caenorhabditis elegans dauer larva: Developmental effects of pheromone, food, and temperature
-
Golden JW, Riddle DL (1984) The Caenorhabditis elegans dauer larva: Developmental effects of pheromone, food, and temperature. Dev Biol 102(2):368-378.
-
(1984)
Dev Biol
, vol.102
, Issue.2
, pp. 368-378
-
-
Golden, J.W.1
Riddle, D.L.2
-
10
-
-
72449211854
-
Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans
-
Kim K, et al. (2009) Two chemoreceptors mediate developmental effects of dauer pheromone in C. elegans. Science 326(5955):994-998.
-
(2009)
Science
, vol.326
, Issue.5955
, pp. 994-998
-
-
Kim, K.1
-
11
-
-
80052849829
-
Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes
-
McGrath PT, et al. (2011) Parallel evolution of domesticated Caenorhabditis species targets pheromone receptor genes. Nature 477(7364):321-325.
-
(2011)
Nature
, vol.477
, Issue.7364
, pp. 321-325
-
-
McGrath, P.T.1
-
12
-
-
84862576525
-
Interaction of structure-specific and promiscuous G-proteincoupled receptors mediates small-molecule signaling in Caenorhabditis elegans
-
Park D, et al. (2012) Interaction of structure-specific and promiscuous G-proteincoupled receptors mediates small-molecule signaling in Caenorhabditis elegans. Proc Natl Acad Sci USA 109(25):9917-9922.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.25
, pp. 9917-9922
-
-
Park, D.1
-
13
-
-
77950200010
-
The genetics of ageing
-
Kenyon CJ (2010) The genetics of ageing. Nature 464(7288):504-512.
-
(2010)
Nature
, vol.464
, Issue.7288
, pp. 504-512
-
-
Kenyon, C.J.1
-
14
-
-
84887610902
-
Genetic pathway for dauer larva formation in nematode, Caenorhabditis elegans
-
Riddle DL (1977) Genetic pathway for dauer larva formation in nematode, Caenorhabditis elegans. Genetics 86(2):S51-S52.
-
(1977)
Genetics
, vol.86
, Issue.2
-
-
Riddle, D.L.1
-
15
-
-
34848868499
-
The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling
-
Shaw WM, Luo S, Landis J, Ashraf J, Murphy CT (2007) The C. elegans TGF-beta Dauer pathway regulates longevity via insulin signaling. Curr Biol 17(19):1635-1645.
-
(2007)
Curr Biol
, vol.17
, Issue.19
, pp. 1635-1645
-
-
Shaw, W.M.1
Luo, S.2
Landis, J.3
Ashraf, J.4
Murphy, C.T.5
-
16
-
-
0028930267
-
Genes that regulate both development and longevity in Caenorhabditis elegans
-
Larsen PL, Albert PS, Riddle DL (1995) Genes that regulate both development and longevity in Caenorhabditis elegans. Genetics 139(4):1567-1583.
-
(1995)
Genetics
, vol.139
, Issue.4
, pp. 1567-1583
-
-
Larsen, P.L.1
Albert, P.S.2
Riddle, D.L.3
-
17
-
-
0037470501
-
The endocrine regulation of aging by insulin-like signals
-
Tatar M, Bartke A, Antebi A (2003) The endocrine regulation of aging by insulin-like signals. Science 299(5611):1346-1351.
-
(2003)
Science
, vol.299
, Issue.5611
, pp. 1346-1351
-
-
Tatar, M.1
Bartke, A.2
Antebi, A.3
-
18
-
-
0347854376
-
Regulation of C. elegans longevity by specific gustatory and olfactory neurons
-
Alcedo J, Kenyon C (2004) Regulation of C. elegans longevity by specific gustatory and olfactory neurons. Neuron 41(1):45-55.
-
(2004)
Neuron
, vol.41
, Issue.1
, pp. 45-55
-
-
Alcedo, J.1
Kenyon, C.2
-
19
-
-
29344431870
-
Lifespan extending activity of substances secreted by the nematode Caenorhabditis elegans that include the dauer-inducing pheromone
-
Kawano T, et al. (2005) Lifespan extending activity of substances secreted by the nematode Caenorhabditis elegans that include the dauer-inducing pheromone. Biosci Biotechnol Biochem 69(12):2479-2481.
-
(2005)
Biosci Biotechnol Biochem
, vol.69
, Issue.12
, pp. 2479-2481
-
-
Kawano, T.1
-
20
-
-
13944269223
-
The plasticity of aging: Insights from long-lived mutants
-
Kenyon C (2005) The plasticity of aging: Insights from long-lived mutants. Cell 120(4): 449-460.
-
(2005)
Cell
, vol.120
, Issue.4
, pp. 449-460
-
-
Kenyon, C.1
-
21
-
-
2542643174
-
Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans
-
Huang C, Xiong C, Kornfeld K (2004) Measurements of age-related changes of physiological processes that predict lifespan of Caenorhabditis elegans. Proc Natl Acad Sci USA 101(21):8084-8089.
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, Issue.21
, pp. 8084-8089
-
-
Huang, C.1
Xiong, C.2
Kornfeld, K.3
-
22
-
-
0029123058
-
Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress
-
Lithgow GJ, White TM, Melov S, Johnson TE (1995) Thermotolerance and extended life-span conferred by single-gene mutations and induced by thermal stress. Proc Natl Acad Sci USA 92(16):7540-7544.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, Issue.16
, pp. 7540-7544
-
-
Lithgow, G.J.1
White, T.M.2
Melov, S.3
Johnson, T.E.4
-
23
-
-
33751203889
-
Dietary deprivation extends lifespan in Caenorhabditis elegans
-
Lee GD, et al. (2006) Dietary deprivation extends lifespan in Caenorhabditis elegans. Aging Cell 5(6):515-524.
-
(2006)
Aging Cell
, vol.5
, Issue.6
, pp. 515-524
-
-
Lee, G.D.1
-
24
-
-
0024385843
-
Alterations of life span in the nematode Caenorhabditis elegans under monoxenic culture conditions
-
Hosono R, Nishimoto S, Kuno S (1989) Alterations of life span in the nematode Caenorhabditis elegans under monoxenic culture conditions. Exp Gerontol 24(3): 251-264.
-
(1989)
Exp Gerontol
, vol.24
, Issue.3
, pp. 251-264
-
-
Hosono, R.1
Nishimoto, S.2
Kuno, S.3
-
25
-
-
3943071801
-
Sirtuin activators mimic caloric restriction and delay ageing in metazoans
-
Wood JG, et al. (2004) Sirtuin activators mimic caloric restriction and delay ageing in metazoans. Nature 430(7000):686-689.
-
(2004)
Nature
, vol.430
, Issue.7000
, pp. 686-689
-
-
Wood, J.G.1
-
26
-
-
33947424778
-
G protein-coupled receptor systems and their lipid environment in health disorders during aging
-
Alemany R, et al. (2007) G protein-coupled receptor systems and their lipid environment in health disorders during aging. Biochim Biophys Acta 1768(4):964-975.
-
(2007)
Biochim Biophys Acta
, vol.1768
, Issue.4
, pp. 964-975
-
-
Alemany, R.1
-
27
-
-
67949102053
-
Recent progress in the biology and physiology of sirtuins
-
Finkel T, Deng CX, Mostoslavsky R (2009) Recent progress in the biology and physiology of sirtuins. Nature 460(7255):587-591.
-
(2009)
Nature
, vol.460
, Issue.7255
, pp. 587-591
-
-
Finkel, T.1
Deng, C.X.2
Mostoslavsky, R.3
-
28
-
-
50649099122
-
Aging and survival: The genetics of life span extension by dietary restriction
-
Mair W, Dillin A (2008) Aging and survival: The genetics of life span extension by dietary restriction. Annu Rev Biochem 77:727-754.
-
(2008)
Annu Rev Biochem
, vol.77
, pp. 727-754
-
-
Mair, W.1
Dillin, A.2
-
29
-
-
71849105308
-
The Caenorhabditis elegans sirtuin gene, sir-2.1, is widely expressed and induced upon caloric restriction
-
Bamps S, Wirtz J, Savory FR, Lake D, Hope IA (2009) The Caenorhabditis elegans sirtuin gene, sir-2.1, is widely expressed and induced upon caloric restriction. Mech Ageing Dev 130(11-12):762-770.
-
(2009)
Mech Ageing Dev
, vol.130
, Issue.11-12
, pp. 762-770
-
-
Bamps, S.1
Wirtz, J.2
Savory, F.R.3
Lake, D.4
Hope, I.A.5
-
30
-
-
63549108476
-
Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans
-
Greer EL, Brunet A (2009) Different dietary restriction regimens extend lifespan by both independent and overlapping genetic pathways in C. elegans. Aging Cell 8(2): 113-127.
-
(2009)
Aging Cell
, vol.8
, Issue.2
, pp. 113-127
-
-
Greer, E.L.1
Brunet, A.2
-
31
-
-
80053099408
-
Sir-2.1 modulates 'calorie-restriction-mediated' prevention of neurodegeneration in Caenorhabditis elegans: Implications for Parkinson's disease
-
Jadiya P, et al. (2011) Sir-2.1 modulates 'calorie-restriction-mediated' prevention of neurodegeneration in Caenorhabditis elegans: Implications for Parkinson's disease. Biochem Biophys Res Commun 413(2):306-310.
-
(2011)
Biochem Biophys Res Commun
, vol.413
, Issue.2
, pp. 306-310
-
-
Jadiya, P.1
-
32
-
-
84865246956
-
Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2.1-dependent manner in Caenorhabditis elegans
-
Raynes R, Leckey BD, Jr., Nguyen K, Westerheide SD (2012) Heat shock and caloric restriction have a synergistic effect on the heat shock response in a sir2.1-dependent manner in Caenorhabditis elegans. J Biol Chem 287(34):29045-29053.
-
(2012)
J Biol Chem
, vol.287
, Issue.34
, pp. 29045-29053
-
-
Raynes, R.1
Leckey Jr., B.D.2
Nguyen, K.3
Westerheide, S.D.4
-
33
-
-
38049180882
-
Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans
-
Miller DL, RothMB (2007) Hydrogen sulfide increases thermotolerance and lifespan in Caenorhabditis elegans. Proc Natl Acad Sci USA 104(51):20618-20622.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.51
, pp. 20618-20622
-
-
Miller, D.L.1
Roth, M.B.2
-
34
-
-
80053168829
-
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
-
Burnett C, et al. (2011) Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila. Nature 477(7365):482-485.
-
(2011)
Nature
, vol.477
, Issue.7365
, pp. 482-485
-
-
Burnett, C.1
-
35
-
-
34848927457
-
Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans
-
Bass TM, Weinkove D, Houthoofd K, Gems D, Partridge L (2007) Effects of resveratrol on lifespan in Drosophila melanogaster and Caenorhabditis elegans. Mech Ageing Dev 128(10):546-552.
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.10
, pp. 546-552
-
-
Bass, T.M.1
Weinkove, D.2
Houthoofd, K.3
Gems, D.4
Partridge, L.5
-
36
-
-
33744976074
-
C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span
-
Berdichevsky A, Viswanathan M, Horvitz HR, Guarente L (2006) C. elegans SIR-2.1 interacts with 14-3-3 proteins to activate DAF-16 and extend life span. Cell 125(6): 1165-1177.
-
(2006)
Cell
, vol.125
, Issue.6
, pp. 1165-1177
-
-
Berdichevsky, A.1
Viswanathan, M.2
Horvitz, H.R.3
Guarente, L.4
-
37
-
-
80053460544
-
The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO
-
Rizki G, et al. (2011) The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO. PLoS Genet 7(9):e1002235.
-
(2011)
PLoS Genet
, vol.7
, Issue.9
-
-
Rizki, G.1
-
38
-
-
50049116926
-
C. elegans dauer formation and the molecular basis of plasticity
-
Fielenbach N, Antebi A (2008) C. elegans dauer formation and the molecular basis of plasticity. Genes Dev 22(16):2149-2165.
-
(2008)
Genes Dev
, vol.22
, Issue.16
, pp. 2149-2165
-
-
Fielenbach, N.1
Antebi, A.2
-
39
-
-
34247563364
-
A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling
-
Gerisch B, et al. (2007) A bile acid-like steroid modulates Caenorhabditis elegans lifespan through nuclear receptor signaling. Proc Natl Acad Sci USA 104(12): 5014-5019.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.12
, pp. 5014-5019
-
-
Gerisch, B.1
-
40
-
-
0030776478
-
The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway
-
Patterson GI, Koweek A, Wong A, Liu Y, Ruvkun G (1997) The DAF-3 Smad protein antagonizes TGF-beta-related receptor signaling in the Caenorhabditis elegans dauer pathway. Genes Dev 11(20):2679-2690.
-
(1997)
Genes Dev
, vol.11
, Issue.20
, pp. 2679-2690
-
-
Patterson, G.I.1
Koweek, A.2
Wong, A.3
Liu, Y.4
Ruvkun, G.5
-
41
-
-
77956821042
-
The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling
-
Yamawaki TM, et al. (2010) The somatic reproductive tissues of C. elegans promote longevity through steroid hormone signaling. PLoS Biol 8(8):e1000468.
-
(2010)
PLoS Biol
, vol.8
, Issue.8
-
-
Yamawaki, T.M.1
-
42
-
-
84871695502
-
DSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner
-
Banerjee KK, et al. (2012) dSir2 in the adult fat body, but not in muscles, regulates life span in a diet-dependent manner. Cell Rep 2(6):1485-1491.
-
(2012)
Cell Rep
, vol.2
, Issue.6
, pp. 1485-1491
-
-
Banerjee, K.K.1
-
43
-
-
80053134340
-
Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes
-
Viswanathan M, Guarente L (2011) Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes. Nature 477(7365):E1-E2.
-
(2011)
Nature
, vol.477
, Issue.7365
-
-
Viswanathan, M.1
Guarente, L.2
-
44
-
-
0035826271
-
Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
-
Tissenbaum HA, Guarente L (2001) Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans. Nature 410(6825):227-230.
-
(2001)
Nature
, vol.410
, Issue.6825
, pp. 227-230
-
-
Tissenbaum, H.A.1
Guarente, L.2
-
45
-
-
33746245679
-
C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO
-
Wang Y, et al. (2006) C. elegans 14-3-3 proteins regulate life span and interact with SIR-2.1 and DAF-16/FOXO. Mech Ageing Dev 127(9):741-747.
-
(2006)
Mech Ageing Dev
, vol.127
, Issue.9
, pp. 741-747
-
-
Wang, Y.1
-
46
-
-
28244475950
-
Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO
-
Wang Y, Tissenbaum HA (2006) Overlapping and distinct functions for a Caenorhabditis elegans SIR2 and DAF-16/FOXO. Mech Ageing Dev 127(1):48-56.
-
(2006)
Mech Ageing Dev
, vol.127
, Issue.1
, pp. 48-56
-
-
Wang, Y.1
Tissenbaum, H.A.2
-
47
-
-
84858000209
-
The sirtuin SIRT6 regulates lifespan in male mice
-
Kanfi Y, et al. (2012) The sirtuin SIRT6 regulates lifespan in male mice. Nature 483(7388):218-221.
-
(2012)
Nature
, vol.483
, Issue.7388
, pp. 218-221
-
-
Kanfi, Y.1
-
48
-
-
65949093710
-
A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans
-
Macosko EZ, et al. (2009) A hub-and-spoke circuit drives pheromone attraction and social behaviour in C. elegans. Nature 458(7242):1171-1175.
-
(2009)
Nature
, vol.458
, Issue.7242
, pp. 1171-1175
-
-
MacOsko, E.Z.1
-
49
-
-
0032582489
-
Extended life-span and stress resistance in the Drosophila mutant methuselah
-
Lin YJ, Seroude L, Benzer S (1998) Extended life-span and stress resistance in the Drosophila mutant methuselah. Science 282(5390):943-946.
-
(1998)
Science
, vol.282
, Issue.5390
, pp. 943-946
-
-
Lin, Y.J.1
Seroude, L.2
Benzer, S.3
-
50
-
-
84857389789
-
Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila
-
Spindler SR, Li R, Dhahbi JM, Yamakawa A, Sauer F (2012) Novel protein kinase signaling systems regulating lifespan identified by small molecule library screening using Drosophila. PLoS ONE 7(2):e29782.
-
(2012)
PLoS ONE
, vol.7
, Issue.2
-
-
Spindler, S.R.1
Li, R.2
Dhahbi, J.M.3
Yamakawa, A.4
Sauer, F.5
-
51
-
-
60549101499
-
Biosynthesis of the Caenorhabditis elegans dauer pheromone
-
Butcher RA, et al. (2009) Biosynthesis of the Caenorhabditis elegans dauer pheromone. Proc Natl Acad Sci USA 106(6):1875-1879.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.6
, pp. 1875-1879
-
-
Butcher, R.A.1
-
52
-
-
45849133385
-
Transcriptional responses to pathogens in Caenorhabditis elegans
-
Shivers RP, Youngman MJ, Kim DH (2008) Transcriptional responses to pathogens in Caenorhabditis elegans. Curr Opin Microbiol 11(3):251-256.
-
(2008)
Curr Opin Microbiol
, vol.11
, Issue.3
, pp. 251-256
-
-
Shivers, R.P.1
Youngman, M.J.2
Kim, D.H.3
|