Interaction of structure-specific and promiscuous G-protein-coupled receptors mediates small-molecule signaling in Caenorhabditis elegans

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 25, 2012, Pages 9917-9922

  Park, Donha ^a   O'Doherty, Inish ^b,c   Somvanshi, Rishi K ^d   Bethke, Axel ^b,c   Schroeder, Frank C ^b,c   Kumar, Ujendra ^d   Riddle, Donald L ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b United States Department of Agriculture Agricultural Research Service and Boyce Thompson Institute for Plant Research   (United States)

^c Department of Obstetrics Gynecology   (United States)

^d UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Chemosensation; Pheromone signaling; Photoaffinity labeling; Signal transduction; Small molecule receptor

Indexed keywords

CYCLIC AMP; DAF 37 PROTEIN; DAF 38 PROTEIN; G PROTEIN COUPLED RECEPTOR; HETERODIMER; PHEROMONE; UNCLASSIFIED DRUG;

ARTICLE; CAENORHABDITIS ELEGANS; CHEMICAL STRUCTURE; DIMERIZATION; ENZYME INHIBITION; IMMUNOPRECIPITATION; MALE; NONHUMAN; PHOTOAFFINITY LABELING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CROSS LINKING; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; SENSORY NERVE CELL; SIGNAL TRANSDUCTION; TRANSGENIC ORGANISM; WORM;

ANIMALS; CAENORHABDITIS ELEGANS; CYCLIC AMP; DIMERIZATION; IMMUNOPRECIPITATION; NEURONS; PHOTOAFFINITY LABELS; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; SIGNAL TRANSDUCTION;

EID: 84862576525     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1202216109     Document Type: Article

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