Cobalamin and normal prions: A new horizon for cobalamin neurotrophism

Biochimie

Volumn 95, Issue 5, 2013, Pages 1041-1046

  Scalabrino, Giuseppe ^a   Veber, Daniela ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

Cobalamin deficiency; Normal prion protein; Peripheral nervous system; Tumor necrosis factor

Indexed keywords

COBALAMIN; EPIDERMAL GROWTH FACTOR; MYELIN; OCTAPEPTIDE; PRION PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

CENTRAL NERVOUS SYSTEM; HUMAN; IN VITRO STUDY; NERVE CONDUCTION; NEUROTROPISM; NONHUMAN; PATHOGENESIS; PERIPHERAL NERVOUS SYSTEM; POLYNEUROPATHY; PRION DISEASE; PROTEIN EXPRESSION; REVIEW; SCIATIC NERVE; TIBIAL NERVE; VITAMIN DEFICIENCY;

RATTUS;

ANIMALS; HUMANS; PERIPHERAL NERVOUS SYSTEM; PRIONS; TUMOR NECROSIS FACTOR-ALPHA; VITAMIN B 12; VITAMIN B 12 DEFICIENCY;

EID: 84875850929     PISSN: 03009084     EISSN: 61831638     Source Type: Journal    
DOI: 10.1016/j.biochi.2013.01.002     Document Type: Short Survey

References (101)

1. 12) and folate deficiency FASEB J. 7 1993 1344 1353
2. 12 deficiency in elderly patients J. Neuropsychiatry Clin. Neurosci. 24 2012 5 15
3. 12 (cobalamin) deficiency in elderly patients CMAJ 171 2004 251 259
4. J. Lindenbaum, E.B. Healton, D.G. Savage, J.C. Brust, T.J. Garrett, E.R. Podell, P.D. Marcell, S.P. Stabler, and R.H. Allen Neuropsychiatric disorders caused by cobalamin deficiency in the absence of anemia or macrocytosis N. Engl. J. Med. 318 1988 1720 1728
5. R. Carmel Pernicious anemia. The expected findings of very low serum cobalamin levels, anemia, and macrocytosis are often lacking Arch. Intern. Med. 148 1988 1712 1714
6. 12 absorption following partial gastrectomy Acta Neurol. Scand. 59 Suppl. 69 1978 1 77
7. D.S. Saperstein, and R.J. Barohn Peripheral neuropathy due to cobalamin deficiency Curr. Treat. Options Neurol. 4 2002 197 201
8. N. Kumar Nutritional neuropathies Neurol. Clin. 25 2007 209 255
9. G. Scalabrino, D. Veber, and E. Mutti Experimental and clinical evidence of the role of cytokines and growth factors in the pathogenesis of acquired cobalamin-deficient leukoneuropathy Brain Res. Rev. 59 2008 42 54
10. 12 (cobalamin) neurotrophism in adult central nervous system: lessons learned from its deficiency Prog. Neurobiol. 88 2009 203 220
11. 12 deficiency Muscle Nerve 13 1990 158 164
12. G. Tredici, F.R. Buccellato, M. Braga, G. Cavaletti, P. Ciscato, M. Moggio, and G. Scalabrino Polyneuropathy due to cobalamin deficiency in the rat J. Neurol. Sci. 156 1998 18 29
13. M.I. Shevell, and D.S. Rosenblatt The neurology of cobalamin Can. J. Neurol. Sci. 19 1992 472 486
14. D.G. Weir, and J.M. Scott The biochemical basis of neuropathy in cobalamin deficiency Bailliére's Clin. Haematol. 8 1995 479 497
15. D.G. Savage, and J. Lindenbaum Neurological complications of acquired cobalamin deficiency: clinical aspects Bailliére's Clin. Haematol. 8 1995 657 678
16. 12) in subacute combined degeneration and beyond: traditional interpretations and novel theories Exp. Neurol. 192 2005 463 479
17. H. Jakubowski Molecular basis of homocysteine toxicity in humans Cell. Mol. Life Sci. 61 2004 470 487
18. S. Kölker, and J.G. Okun Methylmalonic acid - an endogenous toxin? Cell. Mol. Life Sci. 62 2005 621 624
19. 12) revisited J. Neuropathol. Exp. Neurol. 60 2001 109 120
20. G. Scalabrino, F.R. Buccellato, G. Tredici, A. Morabito, E.C. Lorenzini, R.H. Allen, and J. Lindenbaum Enhanced levels of biochemical markers for cobalamin deficiency in totally gastrectomized rats: uncoupling of the enhancement from the severity of spongy vacuolation in spinal cord Exp. Neurol. 144 1997 258 265
21. 12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE Proc. Natl. Acad. Sci. U.S.A. 106 2009 21930 21935
22. 12(cobalamin)-deficient central neuropathy J. Neuroimmunol. 176 2006 24 33
23. A. Fuso, V. Nicolia, A. Pasqualato, M.T. Fiorenza, R.A. Cavallaro, and S. Scarpa Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency Neurobiol. Aging 32 2011 187 199
24. K. Selmaj, C.S. Raine, M. Farooq, W.T. Norton, and C.F. Brosnan Cytokine cytotoxicity against oligodendrocytes. Apoptosis induced by lymphotoxin J. Immunol. 147 1991 1522 1529
25. J. McLaurin, S. D'Souza, J. Stewart, M. Blain, A. Beaudet, J. Nalbantoglu, and J.P. Antel Effect of tumor necrosis factor α and β on human oligodendrocytes and neurons in culture Int. J. Dev. Neurosci. 13 1995 369 381
26. 12 Cell. Death Differ. 4 1997 233 241
27. C.E. Orozco-Barrios, S.F. Battaglia-Hsu, M.L. Arango-Rodriguez, J. Ayala-Davila, C. Chery, J.M. Alberto, H. Schroeder, J.L. Daval, D. Martinez-Fong, and J.L. Gueant Vitamin B12-impaired metabolism produces apoptosis and Parkinson phenotype in rats expressing the transcobalamin-oleosin chimera in substantia nigra PLoS One 4 2009 e8268
28. S.B. Prusiner Prions Proc. Natl. Acad. Sci. U.S.A. 95 1998 13363 13383
29. C. Wechselberger, S. Wurm, W. Pfarr, and O. Höglinger The physiological functions of prion protein Exp. Cell. Res. 281 2002 1 8
30. A. Aguzzi, F. Baumann, and J. Bremer The prion's elusive reason for being Annu. Rev. Neurosci. 31 2008 439 477
31. R. Linden, V.R. Martins, M.A. Prado, M. Cammarota, I. Izquierdo, and R.R. Brentani Physiology of the prion protein Physiol. Rev. 88 2008 673 728
32. L.B. Chiarini, A.R. Freitas, S.M. Zanata, R.R. Brentani, V.R. Martins, and R. Linden Cellular prion protein transduces neuroprotective signals EMBO J. 21 2002 3317 3326
33. S. Hoshino, K. Inoue, T. Yokoyama, S. Kobayashi, T. Asakura, A. Teramoto, and S. Itohara Prions prevent brain damage after experimental brain injury: a preliminary report Acta Neurochir. 86 Suppl. 2003 297 299
34. X. Roucou, M. Gains, and A.C. LeBlanc Neuroprotective functions of prion protein J. Neurosci. Res. 75 2004 153 161
35. X. Roucou, and A.C. LeBlanc Cellular prion protein neuroprotective function: implications in prion diseases J. Mol. Med. 83 2005 3 11
36. C): its physiological function and role in disease Biochim. Biophys. Acta 1772 2007 629 644
37. W. Hu, B. Kieseier, E. Frohman, T.N. Eagar, R.N. Rosenberg, H.P. Hartung, and O. Stüve Prion proteins: physiological functions and role in neurological disorders J. Neurol. Sci. 264 2008 1 8
38. E. Biasini, J.A. Turnbaugh, U. Unterberger, and D.A. Harris Prion protein at the crossroads of physiology and disease Trends Neurosci. 35 2012 92 103
39. W. Hu, R.N. Rosenberg, and O. Stüve Prion proteins: a biological role beyond prion diseases Acta Neurol. Scand. 116 2007 75 82
40. D. Völkel, K. Zimmermann, I. Zerr, M. Bodemer, T. Lindner, P.L. Turecek, S. Poser, and H.P. Schwarz Immunochemical determination of cellular prion protein in plasma from healthy subjects and patients with sporadic CJD or other neurologic diseases Transfusion 41 2001 441 448
41. A. Castagna, N. Campostrini, A. Farinazzo, G. Zanusso, S. Monaco, and P.G. Righetti Comparative two-dimensional mapping of prion protein isoforms in human cerebrospinal fluid and central nervous system Electrophoresis 23 2002 339 346
42. N. Picard-Hagen, V. Gayrard, C. Viguié, M. Moudjou, C. Imbs, and P.L. Toutain Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep J. Gen. Virol. 87 2006 3723 3727
43. J. Bremer, F. Baumann, C. Tiberi, C. Wessig, H. Fischer, P. Schwarz, A.D. Steele, K.V. Toyka, K.A. Nave, J. Weis, and A. Aguzzi Axonal prion protein is required for peripheral myelin maintenance Nat. Neurosci. 13 2010 310 318
44. A.D. Steele, S. Lindquist, and A. Aguzzi The prion protein knockout mouse Prion 1 2007 83 93
45. D. Westaway, S.J. DeArmond, J. Cayetano-Canlas, D. Groth, D. Foster, S.L. Yang, M. Torchia, G.A. Carlson, and S.B. Prusiner Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins Cell 76 1994 117 129
46. G. Forloni, N. Angeretti, R. Chiesa, E. Monzani, M. Salmona, O. Bugiani, and F. Tagliavini Neurotoxicity of a prion protein fragment Nature 362 1993 543 546
47. R. Chiesa, and D.A. Harris Prion diseases: what is the neurotoxic molecule? Neurobiol. Dis. 8 2001 743 763
48. J. Ma, R. Wollmann, and S. Lindquist Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol Science 298 2002 1781 1785
49. D.A. Harris, and H.L. True New insights into prion structure and toxicity Neuron 50 2006 353 357
50. H.M. Christensen, K. Dikranian, A. Li, K.C. Baysac, K.C. Walls, J.W. Olney, K.A. Roth, and D.A. Harris A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death Am. J. Pathol. 176 2010 2695 2706
51. I.H. Solomon, J.A. Schepker, and D.A. Harris Prion neurotoxicity: insights from prion protein mutants Curr. Issues Mol. Biol. 12 2010 51 61
52. H. Sauer, K. Wefer, V. Vetrugno, M. Pocchiari, C. Gissel, A. Sachinidis, J. Hescheler, and M. Wartenberg Regulation of intrinsic prion protein by growth factors and TNF-α: the role of intracellular reactive oxygen species Free Radic. Biol. Med. 35 2003 586 594
53. J. Satoh, K. Kurohara, M. Yukitake, and Y. Kuroda Constitutive and cytokine-inducible expression of prion protein gene in human neural cell lines J. Neuropathol. Exp. Neurol. 57 1998 131 139
54. C. Kuwahara, A. Kubosaki, T. Nishimura, Y. Nasu, Y. Nakamura, K. Saeki, Y. Matsumoto, and T. Onodera Enhanced expression of cellular prion protein gene by insulin or nerve growth factor in immortalized mouse neuronal precursor cell lines Biochem. Biophys. Res. Commun. 268 2000 763 766
55. C expression: nerve growth factor (NGF) activates the prion gene promoter through the MEK1 pathway in PC12 cells Neurosci. Lett. 400 2006 58 62
56. J.I. Kim, W.K. Ju, J.H. Choi, E. Choi, R.I. Carp, H.M. Wisniewski, and Y.S. Kim Expression of cytokine genes and increased nuclear factor-kappa B activity in the brains of scrapie-infected mice Mol. Brain Res. 73 1999 17 27
57. D.R. Brown, R.S. Nicholas, and L. Canevari Lack of prion protein expression results in a neuronal phenotype sensitive to stress J. Neurosci. Res. 67 2002 211 224
58. C. Julius, M. Heikenwalder, P. Schwarz, A. Marcel, M. Karin, M. Prinz, M. Pasparakis, and A. Aguzzi Prion propagation in mice lacking central nervous system NF-κB signalling J. Gen. Virol. 89 2008 1545 1550
59. J. Follet, C. Lemaire-Vieille, F. Blanquet-Grossard, V. Podevin-Dimster, S. Lehmann, J.P. Chauvin, J.P. Decavel, R. Varea, J. Grassi, M. Fontès, and J.Y. Cesbron PrP expression and replication by Schwann cells: implications in prion spreading J. Virol. 76 2002 2434 2439
60. M.J. Ford, L.J. Burton, R.J. Morris, and S.M. Hall Selective expression of prion protein in peripheral tissues of the adult mouse Neuroscience 113 2002 177 192
61. C region and cobalamin-deficient polyneuropathy of the rat Muscle Nerve 44 2011 957 967
62. K.E. Nazor, T. Seward, and G.C. Telling Motor behavioral and neuropathological deficits in mice deficient for normal prion protein expression Biochim. Biophys. Acta 1772 2007 645 653
63. C J. Neurosci. 25 2005 4879 4888
64. M. Polymenidou, R. Moos, M. Scott, C. Sigurdson, Y.Z. Shi, B. Yajima, I. Hafner-Bratkovic, R. Jerala, S. Hornemann, K. Wuthrich, A. Bellon, M. Vey, G. Garen, M.N. James, N. Kav, and A. Aguzzi The POM monoclonals: a comprehensive set of antibodies to non-overlapping prion protein epitopes PLoS One 3 2008 e3872
65. G. Mitteregger, M. Vosko, B. Krebs, W. Xiang, V. Kohlmannsperger, S. Nölting, G.F. Hamann, and H.A. Kretzschmar The role of the octarepeat region in neuroprotective function of the cellular prion protein Brain Pathol. 17 2007 174 183
66. C-mRNA and copper levels in rat central nervous system Exp. Neurol. 233 2012 380 390
67. K. Xu, X. Wang, Q. Shi, C. Chen, C. Tian, X.L. Li, R.M. Zhou, Y.L. Chu, and X.P. Dong Human prion protein mutants with deleted and inserted octarepeats undergo different pathways to trigger cell apoptosis J. Mol. Neurosci. 43 2011 225 234
68. S. Mead Prion disease genetics Eur. J. Hum. Genet. 14 2006 273 281
69. S. Mead, M. Poulter, J. Beck, T.E. Webb, T.A. Campbell, J.M. Linehan, M. Desbruslais, S. Joiner, J.D. Wadsworth, A. King, P. Lantos, and J. Collinge Inherited prion disease with six octapeptide repeat insertional mutation-molecular analysis of phenotypic heterogeneity Brain 129 2006 2297 2317
70. S. Mead, T.E. Webb, T.A. Campbell, J. Beck, J.M. Linehan, S. Rutherfoord, S. Joiner, J.D. Wadsworth, J. Heckmann, S. Wroe, L. Doey, A. King, and J. Collinge Inherited prion disease with 5-OPRI. Phenotype modification by repeat length and codon 129 Neurology 69 2007 730 738
71. A. Li, S. Sakaguchi, R. Atarashi, B.C. Roy, R. Nakaoke, K. Arima, N. Okimura, J. Kopacek, and K. Shigematsu Identification of a novel gene encoding a PrP-like protein expressed as chimeric transcripts fused to PrP exon 1/2 in ataxic mouse line with a disrupted PrP gene Cell. Mol. Neurobiol. 20 2000 553 567
72. C and its homologue Dpl Trends Neurosci. 25 2002 150 154
73. F. Baumann, M. Tolnay, C. Brabeck, J. Pahnke, U. Kloz, H.H. Niemann, M. Heikenwalder, T. Rülicke, A. Bürkle, and A. Aguzzi Lethal recessive myelin toxicity of prion protein lacking its central domain EMBO J. 26 2007 538 547
74. R. Stella, M.L. Massimino, M.C. Sorgato, and A. Bertoli Prion and TNFα: TAC(E)it agreement between the prion protein and cell signaling Cell Cycle 9 2010 4616 4621
75. V. Lewis, and N.M. Hooper The role of lipid rafts in prion protein biology Front. Biosci. 16 2011 151 168
76. I.B. Van den Veyver Genetic effects of methylation diets Annu. Rev. Nutr. 22 2002 255 282
77. E.J. Richards Inherited epigenetic variation - revisiting soft inheritance Nat. Rev. Genet. 7 2006 395 401
78. A. Bird DNA methylation patterns and epigenetic memory Genes Dev. 16 2002 6 21
79. R. Jaenisch, and A. Bird Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals Nat. Genet. 33 2003 245 254
80. C.L. Ulrey, L. Liu, L.G. Andrews, and T.O. Tollefsbol The impact of metabolism on DNA methylation Hum. Mol. Genet. 14 2005 R139 R147
81. K.P. Nightingale, L.P. O'Neill, and B.M. Turner Histone modifications: signaling receptors and potential elements of a heritable epigenetic code Curr. Opin. Genet. Dev. 16 2006 125 136
82. E.A. Vucic, C.J. Brown, and W.L. Lam Epigenetics of cancer progression Pharmacogenomics 9 2008 215 234
83. R.J. Klose, and A.P. Bird Genomic DNA methylation: the mark and its mediators Trends Biochem. Sci. 31 2006 89 97
84. M.F. Mehler Epigenetic principles and mechanisms underlying nervous system functions in health and disease Prog. Neurobiol. 86 2008 305 341
85. P.A. Wade Methyl CpG-binding proteins and transcriptional repression Bioessays 23 2001 1131 1137
86. L. Ooi, and I.C. Wood Regulation of gene expression in the nervous system Biochem. J. 414 2008 327 341
87. 12 J. Biol. Chem. 278 2003 20778 20784
88. V. Marguerite, M. Beri-Dexheimer, S. Ortiou, J.L. Guéant, and M. Merten Cobalamin potentiates vinblastine cytotoxicity through downregulation of mdr-1 gene expression in HepG2 cells Cell. Physiol. Biochem. 20 2007 967 976
89. N. Yanaka, T.A. Koyama, S.I. Komatsu, E. Nakamura, M. Kanda, and N. Kato Vitamin B6 suppresses NF-kB activation in LPS-stimulated mouse macrophages Int. J. Mol. Med. 16 2005 1071 1075
90. 12 neuropathy is not due to failure to methylate myelin basic protein J. Neurol. Sci. 72 1986 113 117
91. V. Magnaghi, D. Veber, A. Morabito, F.R. Buccellato, R.C. Melcangi, and G. Scalabrino Decreased GFAP-mRNA expression in spinal cord of cobalamin-deficient rats FASEB J. 16 2002 1820 1822
92. S. Kalra, R. Ahuja, E. Mutti, D. Veber, S. Seetharam, G. Scalabrino, and B. Seetharam Cobalamin-mediated regulation of transcobalamin receptor levels in rat organs Arch. Biochem. Biophys. 463 2007 128 132
93. E. Mutti, V. Magnaghi, D. Veber, A. Faroni, S. Pece, P.P. Di Fiore, and G. Scalabrino Cobalamin deficiency-induced changes of epidermal growth factor (EGF)-receptor expression and EGF levels in rat spinal cord Brain Res. 1376 2011 23 30
94. 12 is a strong determinant of low methionine synthase activity and DNA hypomethylation in gastrectomized rats Digestion 68 2003 133 140
95. D. Veber, E. Mutti, L. Tacchini, E. Gammella, G. Tredici, and G. Scalabrino Indirect down-regulation of nuclear NF-κB levels by cobalamin in the spinal cord and liver of the rat J. Neurosci. Res. 86 2008 1380 1387
96. F.R. Buccellato, M. Miloso, M. Braga, G. Nicolini, A. Morabito, G. Pravettoni, G. Tredici, and G. Scalabrino Myelinolytic lesions in spinal cord of cobalamin-deficient rats are TNF-α-mediated FASEB J. 13 1999 297 304
97. K. Okada, H. Tanaka, K. Temporin, M. Okamoto, Y. Kuroda, H. Moritomo, T. Murase, and H. Yoshikawa Methylcobalamin increases Erk1/2 and Akt activities through the methylation cycle and promotes nerve regeneration in a rat sciatic nerve injury model Exp. Neurol. 222 2010 191 203
98. K. Okada, H. Tanaka, K. Temporin, M. Okamoto, Y. Kuroda, H. Moritomo, T. Murase, and H. Yoshikawa Akt/mammalian target of rapamycin signaling pathway regulates neurite outgrowth in cerebellar granule neurons stimulated by methylcobalamin Neurosci. Lett. 495 2011 201 204
99. E.H. Pezacka, D.W. Jacobsen, K. Luce, and R. Green Glial cells as a model for the role of cobalamin in the nervous system: impaired synthesis of cobalamin coenzymes in cultured human astrocytes following short-term cobalamin-deprivation Biochem. Biophys. Res. Commun. 184 1992 832 839
100. 12) by astrocytes and oligodendrocytes isolated from rat spinal cord Glia 45 2004 406 411
101. M.S. Pathmajeyan, S.A. Patel, J.A. Carroll, T. Seib, J.F. Striebel, R.J. Bridges, and B. Chesebro Increased excitatory amino acid transport into murine prion protein knockout astrocytes cultured in vitro Glia 59 2011 1684 1694