-
1
-
-
0022476747
-
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
-
Basler K, Oesch B, Scott M, et al. Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene. Cell 1986 46 : 417 28.
-
(1986)
Cell
, vol.46
, pp. 417-28
-
-
Basler, K.1
Oesch, B.2
Scott, M.3
-
3
-
-
0027074458
-
Purification and properties of the cellular prion protein from Syrian hamster brain
-
Pan KM, Stahl N, Prusiner SB. Purification and properties of the cellular prion protein from Syrian hamster brain. Protein Sci 1992 1 : 1343 52.
-
(1992)
Protein Sci
, vol.1
, pp. 1343-52
-
-
Pan, K.M.1
Stahl, N.2
Prusiner, S.B.3
-
4
-
-
0028844207
-
Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: Structural studies using synthetic peptides
-
Hornshaw MP, McDermott JR, Candy JM, Lakey JH. Copper binding to the N-terminal tandem repeat region of mammalian and avian prion protein: structural studies using synthetic peptides. Biochem Biophys Res Commun 1995 214 : 993 9.
-
(1995)
Biochem Biophys Res Commun
, vol.214
, pp. 993-9
-
-
Hornshaw, M.P.1
McDermott, J.R.2
Candy, J.M.3
Lakey, J.H.4
-
5
-
-
0031444294
-
The cellular prion protein binds copper in vivo
-
Brown DR, Qin K, Herms JW, et al. The cellular prion protein binds copper in vivo. Nature 1997 390 : 684 7.
-
(1997)
Nature
, vol.390
, pp. 684-7
-
-
Brown, D.R.1
Qin, K.2
Herms, J.W.3
-
6
-
-
0037965529
-
Prion protein selectively binds copper(II) ions
-
Stockel J, Safar J, Wallace AC, Cohen FE, Prusiner SB. Prion protein selectively binds copper(II) ions. Biochemistry 1998 37 : 7185 93.
-
(1998)
Biochemistry
, vol.37
, pp. 7185-93
-
-
Stockel, J.1
Safar, J.2
Wallace, A.C.3
Cohen, F.E.4
Prusiner, S.B.5
-
7
-
-
0025212147
-
Cellular isoform of the scrapie agent protein participates in lymphocyte activation
-
Cashman NR, Loertscher R, Nalbantoglu J, et al. Cellular isoform of the scrapie agent protein participates in lymphocyte activation. Cell 1990 61 : 185 92.
-
(1990)
Cell
, vol.61
, pp. 185-92
-
-
Cashman, N.R.1
Loertscher, R.2
Nalbantoglu, J.3
-
8
-
-
0033916257
-
Differential expression of cellular prion protein on human blood and tonsil lymphocytes
-
Antoine N, Cesbron JY, Coumans B, Jolois O, Zorzi W, Heinen E. Differential expression of cellular prion protein on human blood and tonsil lymphocytes. Haematologica 2000 85 : 475 80.
-
(2000)
Haematologica
, vol.85
, pp. 475-80
-
-
Antoine, N.1
Cesbron, J.Y.2
Coumans, B.3
Jolois, O.4
Zorzi, W.5
Heinen, E.6
-
9
-
-
0034088481
-
Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes
-
Durig J, Giese A, Schulz-Schaeffer W, et al. Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes. Br J Haematol 2000 108 : 488 95.
-
(2000)
Br J Haematol
, vol.108
, pp. 488-95
-
-
Durig, J.1
Giese, A.2
Schulz-Schaeffer, W.3
-
10
-
-
0035834915
-
The expression and potential function of cellular prion protein in human lymphocytes
-
Li R, Liu D, Zanusso G, et al. The expression and potential function of cellular prion protein in human lymphocytes. Cell Immunol 2001 207 : 49 58.
-
(2001)
Cell Immunol
, vol.207
, pp. 49-58
-
-
Li, R.1
Liu, D.2
Zanusso, G.3
-
11
-
-
0035895051
-
The normal cellular prion protein is strongly expressed by myeloid dendritic cells
-
Burthem J, Urban B, Pain A, Roberts DJ. The normal cellular prion protein is strongly expressed by myeloid dendritic cells. Blood 2001 98 : 3733 8.
-
(2001)
Blood
, vol.98
, pp. 3733-8
-
-
Burthem, J.1
Urban, B.2
Pain, A.3
Roberts, D.J.4
-
12
-
-
29244465148
-
Prion protein induced signaling cascades in monocytes
-
Krebs B, Dorner-Ciossek C, Schmalzbauer R, Vassallo N, Herms J, Kretzschmar HA. Prion protein induced signaling cascades in monocytes. Biochem Biophys Res Commun 2006 340 : 13 22.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, pp. 13-22
-
-
Krebs, B.1
Dorner-Ciossek, C.2
Schmalzbauer, R.3
Vassallo, N.4
Herms, J.5
Kretzschmar, H.A.6
-
13
-
-
0025910229
-
Molecular biology of prion diseases
-
Prusiner SB. Molecular biology of prion diseases. Science 1991 252 : 1515 22.
-
(1991)
Science
, vol.252
, pp. 1515-22
-
-
Prusiner, S.B.1
-
14
-
-
0023663071
-
Scrapie prion protein contains a phosphatidylinositol glycolipid
-
Stahl N, Borchelt DR, Hsiao K, Prusiner SB. Scrapie prion protein contains a phosphatidylinositol glycolipid. Cell 1987 51 : 229 40.
-
(1987)
Cell
, vol.51
, pp. 229-40
-
-
Stahl, N.1
Borchelt, D.R.2
Hsiao, K.3
Prusiner, S.B.4
-
16
-
-
0842347567
-
Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease
-
Tabaton M, Monaco S, Cordone MP, et al. Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease. Ann Neurol 2004 55 : 294 6.
-
(2004)
Ann Neurol
, vol.55
, pp. 294-6
-
-
Tabaton, M.1
Monaco, S.2
Cordone, M.P.3
-
17
-
-
0030907147
-
Biopsy diagnosis of Creutzfeldt-Jakob disease by western blot: A case report
-
Castellani RJ, Parchi P, Madoff L, Gambetti P, Mckeever P. Biopsy diagnosis of Creutzfeldt-Jakob disease by western blot: a case report. Hum Pathol 1997 28 : 623 6.
-
(1997)
Hum Pathol
, vol.28
, pp. 623-6
-
-
Castellani, R.J.1
Parchi, P.2
Madoff, L.3
Gambetti, P.4
McKeever, P.5
-
18
-
-
33748857338
-
Pathogenesis of prion diseases: Current status and future outlook
-
Aguzzi A, Heikenwalder M. Pathogenesis of prion diseases: current status and future outlook. Nat Rev Microbiol 2006 4 : 765 75.
-
(2006)
Nat Rev Microbiol
, vol.4
, pp. 765-75
-
-
Aguzzi, A.1
Heikenwalder, M.2
-
19
-
-
4644259154
-
Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes
-
Zanusso G, Farinazzo A, Prelli F, et al. Identification of distinct N-terminal truncated forms of prion protein in different Creutzfeldt-Jakob disease subtypes. J Biol Chem 2004 279 : 38936 42.
-
(2004)
J Biol Chem
, vol.279
, pp. 38936-42
-
-
Zanusso, G.1
Farinazzo, A.2
Prelli, F.3
-
20
-
-
0036178360
-
Two-dimensional mapping of three phenotype-associated isoforms of the prion protein in sporadic Creutzfeldt-Jakob disease
-
Zanusso G, Righetti PG, Ferrari S, et al. Two-dimensional mapping of three phenotype-associated isoforms of the prion protein in sporadic Creutzfeldt-Jakob disease. Electrophoresis 2002 23 : 347 55.
-
(2002)
Electrophoresis
, vol.23
, pp. 347-55
-
-
Zanusso, G.1
Righetti, P.G.2
Ferrari, S.3
-
21
-
-
0028351904
-
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Different prion proteins determined by a DNA polymorphism
-
Monari L, Chen SG, Brown P, et al. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism. Proc Natl Acad Sci USA 1994 91 : 2839 42.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 2839-42
-
-
Monari, L.1
Chen, S.G.2
Brown, P.3
-
23
-
-
0025800143
-
A 'unified theory' of prion propagation
-
Weissmann C. A 'unified theory' of prion propagation. Nature 1991 352 : 679 83.
-
(1991)
Nature
, vol.352
, pp. 679-83
-
-
Weissmann, C.1
-
24
-
-
28444431651
-
Clinical and differential diagnosis of Creutzfeldt-Jakob disease
-
Poser S, Zerr I, Schroeter A, et al. Clinical and differential diagnosis of Creutzfeldt-Jakob disease. Arch Virol Suppl 2000 16 : 153 9.
-
(2000)
Arch Virol Suppl
, vol.16
, pp. 153-9
-
-
Poser, S.1
Zerr, I.2
Schroeter, A.3
-
25
-
-
0345621492
-
Pathology of variant Creutzfeldt-Jakob disease
-
Ironside JW. Pathology of variant Creutzfeldt-Jakob disease. Arch Virol Suppl 2000 16 : 143 51.
-
(2000)
Arch Virol Suppl
, vol.16
, pp. 143-51
-
-
Ironside, J.W.1
-
27
-
-
33748743547
-
Gerstmann-Straussler-Scheinker disease. I. human diseases
-
Liberski PP, Budka H. Gerstmann-Straussler-Scheinker disease. I. human diseases. Folia Neuropathol 2004 42 (Suppl. B 120 40.
-
(2004)
Folia Neuropathol
, vol.42
, pp. 120-40
-
-
Liberski, P.P.1
Budka, H.2
-
28
-
-
33745035726
-
Barriers to autopsy: Creutzfeldt-Jakob disease in New York state
-
Lillquist PP, Thomas N, Belay ED, Schonberger LB, Morse D. Barriers to autopsy: Creutzfeldt-Jakob disease in New York state. Neuroepidemiology 2006 26 : 207 11.
-
(2006)
Neuroepidemiology
, vol.26
, pp. 207-11
-
-
Lillquist, P.P.1
Thomas, N.2
Belay, E.D.3
Schonberger, L.B.4
Morse, D.5
-
29
-
-
0032747378
-
How to improve the clinical diagnosis of Creutzfeldt-Jakob disease
-
Poser S, Mollenhauer B, Kraubeta A, et al. How to improve the clinical diagnosis of Creutzfeldt-Jakob disease. Brain 1999 122 (Pt 12 2345 51.
-
(1999)
Brain
, vol.122
, Issue.12
, pp. 2345-51
-
-
Poser, S.1
Mollenhauer, B.2
Kraubeta, A.3
-
30
-
-
33751395467
-
Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep
-
Picard-Hagen N, Gayrard V, Viguie C, Moudjou M, Imbs C, Toutain PL. Prion protein in the cerebrospinal fluid of healthy and naturally scrapie-affected sheep. J Gen Virol 2006 87 (Pt 12 3723 7.
-
(2006)
J Gen Virol
, vol.87
, Issue.12
, pp. 3723-7
-
-
Picard-Hagen, N.1
Gayrard, V.2
Viguie, C.3
Moudjou, M.4
Imbs, C.5
Toutain, P.L.6
-
31
-
-
33747689817
-
CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease
-
Sanchez-Juan P, Green A, Ladogana A, et al. CSF tests in the differential diagnosis of Creutzfeldt-Jakob disease. Neurology 2006 67 : 637 43.
-
(2006)
Neurology
, vol.67
, pp. 637-43
-
-
Sanchez-Juan, P.1
Green, A.2
Ladogana, A.3
-
32
-
-
33644877815
-
Diagnostic value of 14-3-3beta immunoblot and T-tau/P-tau ratio in clinically suspected Creutzfeldt-Jakob disease
-
Blennow K, Johansson A, Zetterberg H. Diagnostic value of 14-3-3beta immunoblot and T-tau/P-tau ratio in clinically suspected Creutzfeldt-Jakob disease. Int J Mol Med 2005 16 : 1147 9.
-
(2005)
Int J Mol Med
, vol.16
, pp. 1147-9
-
-
Blennow, K.1
Johansson, A.2
Zetterberg, H.3
-
33
-
-
33645750334
-
Emerging pharmacotherapies for Creutzfeldt-Jakob disease
-
Korth C, Peters PJ. Emerging pharmacotherapies for Creutzfeldt-Jakob disease. Arch Neurol 2006 63 : 497 501.
-
(2006)
Arch Neurol
, vol.63
, pp. 497-501
-
-
Korth, C.1
Peters, P.J.2
-
34
-
-
0035899413
-
Antibodies inhibit prion propagation and clear cell cultures of prion infectivity
-
Peretz D, Williamson RA, Kaneko K, et al. Antibodies inhibit prion propagation and clear cell cultures of prion infectivity. Nature 2001 412 : 739 43.
-
(2001)
Nature
, vol.412
, pp. 739-43
-
-
Peretz, D.1
Williamson, R.A.2
Kaneko, K.3
-
35
-
-
0037422133
-
Monoclonal antibodies inhibit prion replication and delay the development of prion disease
-
White AR, Enever P, Tayebi M, et al. Monoclonal antibodies inhibit prion replication and delay the development of prion disease. Nature 2003 422 : 80 83.
-
(2003)
Nature
, vol.422
, pp. 80-83
-
-
White, A.R.1
Enever, P.2
Tayebi, M.3
-
36
-
-
0038578675
-
Efficient and specific down-regulation of prion protein expression by RNAi
-
Tilly G, Chapuis J, Vilette D, Laude H, Vilotte JL. Efficient and specific down-regulation of prion protein expression by RNAi. Biochem Biophys Res Commun 2003 305 : 548 51.
-
(2003)
Biochem Biophys Res Commun
, vol.305
, pp. 548-51
-
-
Tilly, G.1
Chapuis, J.2
Vilette, D.3
Laude, H.4
Vilotte, J.L.5
-
37
-
-
0038783253
-
Specific inhibition of pathological prion protein accumulation by small interfering RNAs
-
Daude N, Marella M, Chabry J. Specific inhibition of pathological prion protein accumulation by small interfering RNAs. J Cell Sci 2003 116 (Pt 13 2775 9.
-
(2003)
J Cell Sci
, vol.116
, Issue.13
, pp. 2775-9
-
-
Daude, N.1
Marella, M.2
Chabry, J.3
-
38
-
-
0035859806
-
Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease
-
Korth C, May BC, Cohen FE, Prusiner SB. Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease. Proc Natl Acad Sci USA 2001 98 : 9836 41.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 9836-41
-
-
Korth, C.1
May, B.C.2
Cohen, F.E.3
Prusiner, S.B.4
-
40
-
-
14644389457
-
A possible pharmacological explanation for quinacrine failure to treat prion diseases: Pharmacokinetic investigations in a ovine model of scrapie
-
Gayrard V, Picard-Hagen N, Viguie C, Laroute V, Andreoletti O, Toutain PL. A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie. Br J Pharmacol 2005 144 : 386 93.
-
(2005)
Br J Pharmacol
, vol.144
, pp. 386-93
-
-
Gayrard, V.1
Picard-Hagen, N.2
Viguie, C.3
Laroute, V.4
Andreoletti, O.5
Toutain, P.L.6
-
41
-
-
0032843132
-
Molecular genetics of human prion diseases in Germany
-
Windl O, Giese A, Schulz-Schaeffer W, et al. Molecular genetics of human prion diseases in Germany. Hum Genet 1999 105 : 244 52.
-
(1999)
Hum Genet
, vol.105
, pp. 244-52
-
-
Windl, O.1
Giese, A.2
Schulz-Schaeffer, W.3
-
42
-
-
0026496257
-
Fatal familial insomnia and familial Creutzfeldt-Jakob disease: Disease phenotype determined by a DNA polymorphism
-
Goldfarb LG, Petersen RB, Tabaton M, et al. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: disease phenotype determined by a DNA polymorphism. Science 1992 258 : 806 8.
-
(1992)
Science
, vol.258
, pp. 806-8
-
-
Goldfarb, L.G.1
Petersen, R.B.2
Tabaton, M.3
-
43
-
-
0026849545
-
Linkage of the Indiana kindred of Gerstmann-Straussler-Scheinker disease to the prion protein gene
-
Dlouhy SR, Hsiao K, Farlow MR, et al. Linkage of the Indiana kindred of Gerstmann-Straussler-Scheinker disease to the prion protein gene. Nat Genet 1992 1 : 64 7.
-
(1992)
Nat Genet
, vol.1
, pp. 64-7
-
-
Dlouhy, S.R.1
Hsiao, K.2
Farlow, M.R.3
-
44
-
-
0037372585
-
PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease
-
Dermaut B, Croes EA, Rademakers R, et al. PRNP Val129 homozygosity increases risk for early-onset Alzheimer's disease. Ann Neurol 2003 53 : 409 12.
-
(2003)
Ann Neurol
, vol.53
, pp. 409-12
-
-
Dermaut, B.1
Croes, E.A.2
Rademakers, R.3
-
45
-
-
0842325637
-
Polymorphisms within the prion (PrP) and prion-like protein (Doppel) genes in AD
-
Golanska E, Hulas-Bigoszewska K, Rutkiewicz E, et al. Polymorphisms within the prion (PrP) and prion-like protein (Doppel) genes in AD. Neurology 2004 62 : 313 5.
-
(2004)
Neurology
, vol.62
, pp. 313-5
-
-
Golanska, E.1
Hulas-Bigoszewska, K.2
Rutkiewicz, E.3
-
46
-
-
0038796590
-
The 129 codon polymorphism of the prion protein gene influences earlier cognitive performance in Down syndrome subjects
-
Del Bo R, Comi GP, Giorda R, et al. The 129 codon polymorphism of the prion protein gene influences earlier cognitive performance in Down syndrome subjects. J Neurol 2003 250 : 688 92.
-
(2003)
J Neurol
, vol.250
, pp. 688-92
-
-
Del Bo, R.1
Comi, G.P.2
Giorda, R.3
-
47
-
-
28644447668
-
Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia
-
Li X, Rowland LP, Mitsumoto H, et al. Prion protein codon 129 genotype prevalence is altered in primary progressive aphasia. Ann Neurol 2005 58 : 858 64.
-
(2005)
Ann Neurol
, vol.58
, pp. 858-64
-
-
Li, X.1
Rowland, L.P.2
Mitsumoto, H.3
-
48
-
-
33645130155
-
Prion protein gene codon 129 modulates clinical course of neurological Wilson disease
-
Grubenbecher S, Stuve O, Hefter H, Korth C. Prion protein gene codon 129 modulates clinical course of neurological Wilson disease. Neuroreport 2006 17 : 549 52.
-
(2006)
Neuroreport
, vol.17
, pp. 549-52
-
-
Grubenbecher, S.1
Stuve, O.2
Hefter, H.3
Korth, C.4
-
49
-
-
33745825195
-
Influence of homozygosity for methionine at codon 129 of the human prion gene on the onset of neurological and hepatic symptoms in Wilson disease
-
Merle U, Stremmel W, Gessner R. Influence of homozygosity for methionine at codon 129 of the human prion gene on the onset of neurological and hepatic symptoms in Wilson disease. Arch Neurol 2006 63 : 982 5.
-
(2006)
Arch Neurol
, vol.63
, pp. 982-5
-
-
Merle, U.1
Stremmel, W.2
Gessner, R.3
-
50
-
-
26444509890
-
The prion gene is associated with human long-term memory
-
Papassotiropoulos A, Wollmer MA, Aguzzi A, Hock C, Nitsch RM, de Quervain DJ. The prion gene is associated with human long-term memory. Hum Mol Genet 2005 14 : 2241 6.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2241-6
-
-
Papassotiropoulos, A.1
Wollmer, M.A.2
Aguzzi, A.3
Hock, C.4
Nitsch, R.M.5
De Quervain, D.J.6
-
51
-
-
0031752715
-
Polymorphism of the prion protein is associated with cognitive impairment in the elderly: The EVA study
-
Berr C, Richard F, Dufouil C, Amant C, Alperovitch A, Amouyel P. Polymorphism of the prion protein is associated with cognitive impairment in the elderly: the EVA study. Neurology 1998 51 : 734 7.
-
(1998)
Neurology
, vol.51
, pp. 734-7
-
-
Berr, C.1
Richard, F.2
Dufouil, C.3
Amant, C.4
Alperovitch, A.5
Amouyel, P.6
-
52
-
-
0041843758
-
Early cognitive decline is associated with prion protein codon 129 polymorphism
-
Croes EA, Dermaut B, Houwing-Duistermaat JJ, et al. Early cognitive decline is associated with prion protein codon 129 polymorphism. Ann Neurol 2003 54 : 275 6.
-
(2003)
Ann Neurol
, vol.54
, pp. 275-6
-
-
Croes, E.A.1
Dermaut, B.2
Houwing-Duistermaat, J.J.3
-
53
-
-
10744222194
-
Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant
-
Walz R, Castro RM, Velasco TR, et al. Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant. Neurology 2003 61 : 1204 10.
-
(2003)
Neurology
, vol.61
, pp. 1204-10
-
-
Walz, R.1
Castro, R.M.2
Velasco, T.R.3
-
54
-
-
0026600865
-
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
-
Bueler H, Fischer M, Lang Y, et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein. Nature 1992 356 : 577 82.
-
(1992)
Nature
, vol.356
, pp. 577-82
-
-
Bueler, H.1
Fischer, M.2
Lang, Y.3
-
55
-
-
0033215478
-
Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel
-
Moore RC, Lee IY, Silverman GL, et al. Ataxia in prion protein (PrP)-deficient mice is associated with upregulation of the novel PrP-like protein doppel. J Mol Biol 1999 292 : 797 817.
-
(1999)
J Mol Biol
, vol.292
, pp. 797-817
-
-
Moore, R.C.1
Lee, I.Y.2
Silverman, G.L.3
-
56
-
-
13344282734
-
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene
-
Sakaguchi S, Katamine S, Nishida N, et al. Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene. Nature 1996 380 : 528 31.
-
(1996)
Nature
, vol.380
, pp. 528-31
-
-
Sakaguchi, S.1
Katamine, S.2
Nishida, N.3
-
57
-
-
0028420937
-
129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal
-
Manson JC, Clarke AR, Hooper ML, Aitchison L, McConnell I, Hope J. 129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal. Mol Neurobiol 1994 8 : 121 7.
-
(1994)
Mol Neurobiol
, vol.8
, pp. 121-7
-
-
Manson, J.C.1
Clarke, A.R.2
Hooper, M.L.3
Aitchison, L.4
McConnell, I.5
Hope, J.6
-
58
-
-
0033049539
-
A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination
-
Nishida N, Tremblay P, Sugimoto T, et al. A mouse prion protein transgene rescues mice deficient for the prion protein gene from purkinje cell degeneration and demyelination. Lab Invest 1999 79 : 689 97.
-
(1999)
Lab Invest
, vol.79
, pp. 689-97
-
-
Nishida, N.1
Tremblay, P.2
Sugimoto, T.3
-
59
-
-
0035865398
-
Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain
-
Rossi D, Cozzio A, Flechsig E, et al. Onset of ataxia and Purkinje cell loss in PrP null mice inversely correlated with Dpl level in brain. EMBO J 2001 20 : 694 702.
-
(2001)
EMBO J
, vol.20
, pp. 694-702
-
-
Rossi, D.1
Cozzio, A.2
Flechsig, E.3
-
60
-
-
0034282872
-
Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss
-
Silverman GL, Qin K, Moore RC, et al. Doppel is an N-glycosylated, glycosylphosphatidylinositol-anchored protein. Expression in testis and ectopic production in the brains of Prnp(0/0) mice predisposed to Purkinje cell loss. J Biol Chem 2000 275 : 26834 41.
-
(2000)
J Biol Chem
, vol.275
, pp. 26834-41
-
-
Silverman, G.L.1
Qin, K.2
Moore, R.C.3
-
61
-
-
0141738255
-
PrP knock-out and PrP transgenic mice in prion research
-
Weissmann C, Flechsig E. PrP knock-out and PrP transgenic mice in prion research. Br Med Bull 2003 66 : 43 60.
-
(2003)
Br Med Bull
, vol.66
, pp. 43-60
-
-
Weissmann, C.1
Flechsig, E.2
-
62
-
-
0028876414
-
Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent
-
Race RE, Priola SA, Bessen RA, et al. Neuron-specific expression of a hamster prion protein minigene in transgenic mice induces susceptibility to hamster scrapie agent. Neuron 1995 15 : 1183 91.
-
(1995)
Neuron
, vol.15
, pp. 1183-91
-
-
Race, R.E.1
Priola, S.A.2
Bessen, R.A.3
-
63
-
-
0030684056
-
Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie
-
Raeber AJ, Race RE, Brandner S, et al. Astrocyte-specific expression of hamster prion protein (PrP) renders PrP knockout mice susceptible to hamster scrapie. EMBO J 1997 16 : 6057 65.
-
(1997)
EMBO J
, vol.16
, pp. 6057-65
-
-
Raeber, A.J.1
Race, R.E.2
Brandner, S.3
-
64
-
-
0031759918
-
PrP expression in B lymphocytes is not required for prion neuroinvasion
-
Klein MA, Frigg R, Raeber AJ, et al. PrP expression in B lymphocytes is not required for prion neuroinvasion. Nat Med 1998 4 : 1429 33.
-
(1998)
Nat Med
, vol.4
, pp. 1429-33
-
-
Klein, M.A.1
Frigg, R.2
Raeber, A.J.3
-
65
-
-
0033616564
-
Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication
-
Raeber AJ, Sailer A, Hegyi I, et al. Ectopic expression of prion protein (PrP) in T lymphocytes or hepatocytes of PrP knockout mice is insufficient to sustain prion replication. Proc Natl Acad Sci USA 1999 96 : 3987 92.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3987-92
-
-
Raeber, A.J.1
Sailer, A.2
Hegyi, I.3
-
66
-
-
33644839257
-
Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus
-
Jouvin-Marche E, Attuil-Audenis V, Aude-Garcia C, et al. Overexpression of cellular prion protein induces an antioxidant environment altering T cell development in the thymus. J Immunol 2006 176 : 3490 97.
-
(2006)
J Immunol
, vol.176
, pp. 3490-97
-
-
Jouvin-Marche, E.1
Attuil-Audenis, V.2
Aude-Garcia, C.3
-
67
-
-
0029863648
-
Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie
-
Fischer M, Rulicke T, Raeber A, et al. Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J 1996 15 : 1255 64.
-
(1996)
EMBO J
, vol.15
, pp. 1255-64
-
-
Fischer, M.1
Rulicke, T.2
Raeber, A.3
-
68
-
-
0025270288
-
The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells
-
Brown HR, Goller NL, Rudelli RD, et al. The mRNA encoding the scrapie agent protein is present in a variety of non-neuronal cells. Acta Neuropathol (Berl) 1990 80 : 1 6.
-
(1990)
Acta Neuropathol (Berl)
, vol.80
, pp. 1-6
-
-
Brown, H.R.1
Goller, N.L.2
Rudelli, R.D.3
-
69
-
-
0036925662
-
Genomic characterization of the human prion protein (PrP) gene locus
-
Makrinou E, Collinge J, Antoniou M. Genomic characterization of the human prion protein (PrP) gene locus. Mamm Genome 2002 13 : 696 703.
-
(2002)
Mamm Genome
, vol.13
, pp. 696-703
-
-
Makrinou, E.1
Collinge, J.2
Antoniou, M.3
-
71
-
-
0037070637
-
PrP-dependent cell adhesion in N2a neuroblastoma cells
-
Mange A, Milhavet O, Umlauf D, Harris D, Lehmann S. PrP-dependent cell adhesion in N2a neuroblastoma cells. FEBS Lett 2002 514 : 159 62.
-
(2002)
FEBS Lett
, vol.514
, pp. 159-62
-
-
Mange, A.1
Milhavet, O.2
Umlauf, D.3
Harris, D.4
Lehmann, S.5
-
72
-
-
18544376071
-
Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth
-
Santuccione A, Sytnyk V, Leshchyns'ka I, Schachner M. Prion protein recruits its neuronal receptor NCAM to lipid rafts to activate p59fyn and to enhance neurite outgrowth. J Cell Biol 2005 169 : 341 54.
-
(2005)
J Cell Biol
, vol.169
, pp. 341-54
-
-
Santuccione, A.1
Sytnyk, V.2
Leshchyns'Ka, I.3
Schachner, M.4
-
73
-
-
0345505687
-
Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival
-
Chen S, Mange A, Dong L, Lehmann S, Schachner M. Prion protein as trans-interacting partner for neurons is involved in neurite outgrowth and neuronal survival. Mol Cell Neurosci 2003 22 : 227 33.
-
(2003)
Mol Cell Neurosci
, vol.22
, pp. 227-33
-
-
Chen, S.1
Mange, A.2
Dong, L.3
Lehmann, S.4
Schachner, M.5
-
75
-
-
0033566067
-
Prions prevent neuronal cell-line death
-
Kuwahara C, Takeuchi AM, Nishimura T, et al. Prions prevent neuronal cell-line death. Nature 1999 400 : 225 6.
-
(1999)
Nature
, vol.400
, pp. 225-6
-
-
Kuwahara, C.1
Takeuchi, A.M.2
Nishimura, T.3
-
76
-
-
0035914410
-
Prion protein protects human neurons against Bax-mediated apoptosis
-
Bounhar Y, Zhang Y, Goodyer CG, LeBlanc A. Prion protein protects human neurons against Bax-mediated apoptosis. J Biol Chem 2001 276 : 39145 9.
-
(2001)
J Biol Chem
, vol.276
, pp. 39145-9
-
-
Bounhar, Y.1
Zhang, Y.2
Goodyer, C.G.3
Leblanc, A.4
-
78
-
-
12844257374
-
Cellular prion protein neuroprotective function: Implications in prion diseases
-
Roucou X, LeBlanc AC. Cellular prion protein neuroprotective function: implications in prion diseases. J Mol Med 2005 83 : 3 11.
-
(2005)
J Mol Med
, vol.83
, pp. 3-11
-
-
Roucou, X.1
Leblanc, A.C.2
-
79
-
-
33746417936
-
Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes
-
Qin K, Zhao L, Tang Y, Bhatta S, Simard JM, Zhao RY. Doppel-induced apoptosis and counteraction by cellular prion protein in neuroblastoma and astrocytes. Neuroscience 2006 141 : 1375 88.
-
(2006)
Neuroscience
, vol.141
, pp. 1375-88
-
-
Qin, K.1
Zhao, L.2
Tang, Y.3
Bhatta, S.4
Simard, J.M.5
Zhao, R.Y.6
-
80
-
-
12144288766
-
Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury
-
Marciano PG, Brettschneider J, Manduchi E, et al. Neuron-specific mRNA complexity responses during hippocampal apoptosis after traumatic brain injury. J Neurosci 2004 24 : 2866 76.
-
(2004)
J Neurosci
, vol.24
, pp. 2866-76
-
-
Marciano, P.G.1
Brettschneider, J.2
Manduchi, E.3
-
81
-
-
0242383484
-
A human prion protein peptide (PrP(59-91)) protects against copper neurotoxicity
-
Chacon MA, Barria MI, Lorca R, Huidobro-Toro JP, Inestrosa NC. A human prion protein peptide (PrP(59-91)) protects against copper neurotoxicity. Mol Psychiatry 2003 8 : 853 62.
-
(2003)
Mol Psychiatry
, vol.8
, pp. 853-62
-
-
Chacon, M.A.1
Barria, M.I.2
Lorca, R.3
Huidobro-Toro, J.P.4
Inestrosa, N.C.5
-
82
-
-
0001552281
-
Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions
-
Shmerling D, Hegyi I, Fischer M, et al. Expression of amino-terminally truncated PrP in the mouse leading to ataxia and specific cerebellar lesions. Cell 1998 93 : 203 14.
-
(1998)
Cell
, vol.93
, pp. 203-14
-
-
Shmerling, D.1
Hegyi, I.2
Fischer, M.3
-
83
-
-
0036645677
-
Cellular prion protein transduces neuroprotective signals
-
Chiarini LB, Freitas AR, Zanata SM, Brentani RR, Martins VR, Linden R. Cellular prion protein transduces neuroprotective signals. EMBO J 2002 21 : 3317 26.
-
(2002)
EMBO J
, vol.21
, pp. 3317-26
-
-
Chiarini, L.B.1
Freitas, A.R.2
Zanata, S.M.3
Brentani, R.R.4
Martins, V.R.5
Linden, R.6
-
85
-
-
0345687168
-
NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells
-
Schneider B, Mutel V, Pietri M, Ermonval M, Mouillet-Richard S, Kellermann O. NADPH oxidase and extracellular regulated kinases 1/2 are targets of prion protein signaling in neuronal and nonneuronal cells. Proc Natl Acad Sci USA 2003 100 : 13326 31.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 13326-31
-
-
Schneider, B.1
Mutel, V.2
Pietri, M.3
Ermonval, M.4
Mouillet-Richard, S.5
Kellermann, O.6
-
86
-
-
0030890097
-
Mossy fibre reorganization in the hippocampus of prion protein null mice
-
Colling SB, Khana M, Collinge J, Jefferys JG. Mossy fibre reorganization in the hippocampus of prion protein null mice. Brain Res 1997 755 : 28 35.
-
(1997)
Brain Res
, vol.755
, pp. 28-35
-
-
Colling, S.B.1
Khana, M.2
Collinge, J.3
Jefferys, J.G.4
-
87
-
-
15844421385
-
Altered circadian activity rhythms and sleep in mice devoid of prion protein
-
Tobler I, Gaus SE, Deboer T, et al. Altered circadian activity rhythms and sleep in mice devoid of prion protein. Nature 1996 380 : 639 42.
-
(1996)
Nature
, vol.380
, pp. 639-42
-
-
Tobler, I.1
Gaus, S.E.2
Deboer, T.3
-
88
-
-
0042200243
-
Cellular prion protein ablation impairs behavior as a function of age
-
Coitinho AS, Roesler R, Martins VR, Brentani RR, Izquierdo I. Cellular prion protein ablation impairs behavior as a function of age. Neuroreport 2003 14 : 1375 9.
-
(2003)
Neuroreport
, vol.14
, pp. 1375-9
-
-
Coitinho, A.S.1
Roesler, R.2
Martins, V.R.3
Brentani, R.R.4
Izquierdo, I.5
-
89
-
-
20244371991
-
Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons
-
Criado JR, Sanchez-Alavez M, Conti B, et al. Mice devoid of prion protein have cognitive deficits that are rescued by reconstitution of PrP in neurons. Neurobiol Dis 2005 19 : 255 65.
-
(2005)
Neurobiol Dis
, vol.19
, pp. 255-65
-
-
Criado, J.R.1
Sanchez-Alavez, M.2
Conti, B.3
-
90
-
-
0029971378
-
Hippocampal slices from prion protein null mice: Disrupted Ca(2+)-activated K+ currents
-
Colling SB, Collinge J, Jefferys JG. Hippocampal slices from prion protein null mice: disrupted Ca(2+)-activated K+ currents. Neurosci Lett 1996 209 : 49 52.
-
(1996)
Neurosci Lett
, vol.209
, pp. 49-52
-
-
Colling, S.B.1
Collinge, J.2
Jefferys, J.G.3
-
91
-
-
0029265461
-
PrP gene dosage and long term potentiation
-
Manson JC, Hope J, Clarke AR, Johnston A, Black C, MacLeod N. PrP gene dosage and long term potentiation. Neurodegeneration 1995 4 : 113 4.
-
(1995)
Neurodegeneration
, vol.4
, pp. 113-4
-
-
Manson, J.C.1
Hope, J.2
Clarke, A.R.3
Johnston, A.4
Black, C.5
MacLeod, N.6
-
92
-
-
0032806450
-
Increased sensitivity to seizures in mice lacking cellular prion protein
-
Walz R, Amaral OB, Rockenbach IC, et al. Increased sensitivity to seizures in mice lacking cellular prion protein. Epilepsia 1999 40 : 1679 82.
-
(1999)
Epilepsia
, vol.40
, pp. 1679-82
-
-
Walz, R.1
Amaral, O.B.2
Rockenbach, I.C.3
-
93
-
-
33646695909
-
Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury
-
Weise J, Sandau R, Schwarting S, et al. Deletion of cellular prion protein results in reduced Akt activation, enhanced postischemic caspase-3 activation, and exacerbation of ischemic brain injury. Stroke 2006 37 : 1296 300.
-
(2006)
Stroke
, vol.37
, pp. 1296-300
-
-
Weise, J.1
Sandau, R.2
Schwarting, S.3
-
94
-
-
26944460813
-
Female-specific neuroprotection against transient brain ischemia observed in mice devoid of prion protein is abolished by ectopic expression of prion protein-like protein
-
Sakurai-Yamashita Y, Sakaguchi S, Yoshikawa D, et al. Female-specific neuroprotection against transient brain ischemia observed in mice devoid of prion protein is abolished by ectopic expression of prion protein-like protein. Neuroscience 2005 136 : 281 7.
-
(2005)
Neuroscience
, vol.136
, pp. 281-7
-
-
Sakurai-Yamashita, Y.1
Sakaguchi, S.2
Yoshikawa, D.3
-
95
-
-
25644433562
-
Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model
-
Shyu WC, Lin SZ, Chiang MF, et al. Overexpression of PrPC by adenovirus-mediated gene targeting reduces ischemic injury in a stroke rat model. J Neurosci 2005 25 : 8967 77.
-
(2005)
J Neurosci
, vol.25
, pp. 8967-77
-
-
Shyu, W.C.1
Lin, S.Z.2
Chiang, M.F.3
-
96
-
-
26944462341
-
Aggravation of ischemic brain injury by prion protein deficiency: Role of ERK-1/-2 and STAT-1
-
Spudich A, Frigg R, Kilic E, et al. Aggravation of ischemic brain injury by prion protein deficiency: role of ERK-1/-2 and STAT-1. Neurobiol Dis 2005 20 : 442 9.
-
(2005)
Neurobiol Dis
, vol.20
, pp. 442-9
-
-
Spudich, A.1
Frigg, R.2
Kilic, E.3
-
97
-
-
33750372639
-
Prion protein expression by mouse dendritic cells is restricted to the nonplasmacytoid subsets and correlates with the maturation state
-
Martinez Del Hoyo G, Lopez-Bravo M, Metharom P, Ardavin C, Aucouturier P. Prion protein expression by mouse dendritic cells is restricted to the nonplasmacytoid subsets and correlates with the maturation state. J Immunol 2006 177 : 6137 42.
-
(2006)
J Immunol
, vol.177
, pp. 6137-42
-
-
Martinez Del Hoyo, G.1
Lopez-Bravo, M.2
Metharom, P.3
Ardavin, C.4
Aucouturier, P.5
-
98
-
-
33744905327
-
Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells
-
Ballerini C, Gourdain P, Bachy V, et al. Functional implication of cellular prion protein in antigen-driven interactions between T cells and dendritic cells. J Immunol 2006 176 : 7254 62.
-
(2006)
J Immunol
, vol.176
, pp. 7254-62
-
-
Ballerini, C.1
Gourdain, P.2
Bachy, V.3
-
99
-
-
14644399854
-
The cellular prion protein modulates phagocytosis and inflammatory response
-
de Almeida CJ, Chiarini LB, da Silva JP, E Silva PM, Martins MA, Linden R. The cellular prion protein modulates phagocytosis and inflammatory response. J Leukoc Biol 2005 77 : 238 46.
-
(2005)
J Leukoc Biol
, vol.77
, pp. 238-46
-
-
De Almeida, C.J.1
Chiarini, L.B.2
Da Silva, J.P.3
Silva, P.M.E.4
Martins, M.A.5
Linden, R.6
-
100
-
-
0033624049
-
Age-related expression of the cellular prion protein in human peripheral blood leukocytes
-
Politopoulou G, Seebach JD, Schmugge M, Schwarz HP, Aguzzi A. Age-related expression of the cellular prion protein in human peripheral blood leukocytes. Haematologica 2000 85 : 580 87.
-
(2000)
Haematologica
, vol.85
, pp. 580-87
-
-
Politopoulou, G.1
Seebach, J.D.2
Schmugge, M.3
Schwarz, H.P.4
Aguzzi, A.5
-
101
-
-
1342329324
-
Prion protein is a component of the multimolecular signaling complex involved in T cell activation
-
Mattei V, Garofalo T, Misasi R, et al. Prion protein is a component of the multimolecular signaling complex involved in T cell activation. FEBS Lett 2004 560 : 14 8.
-
(2004)
FEBS Lett
, vol.560
, pp. 14-8
-
-
Mattei, V.1
Garofalo, T.2
Misasi, R.3
-
102
-
-
10044234042
-
The normal cellular form of prion protein modulates T cell responses
-
Bainbridge J, Walker KB. The normal cellular form of prion protein modulates T cell responses. Immunol Lett 2005 96 : 147 50.
-
(2005)
Immunol Lett
, vol.96
, pp. 147-50
-
-
Bainbridge, J.1
Walker, K.B.2
-
103
-
-
0030850688
-
T-lymphocyte activation and the cellular form of the prion protein
-
Mabbott NA, Brown KL, Manson J, Bruce ME. T-lymphocyte activation and the cellular form of the prion protein. Immunology 1997 92 : 161 5.
-
(1997)
Immunology
, vol.92
, pp. 161-5
-
-
Mabbott, N.A.1
Brown, K.L.2
Manson, J.3
Bruce, M.E.4
|