Vitamin B12 deficiency reduces proliferation and promotes differentiation of neuroblastoma cells and up-regulates PP2A, proNGF, and TACE

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 51, 2009, Pages 21930-21935

  Battaglia Hsu, Shyue Fang ^a   Akchiche, Nassila ^a   Noel, Nicole ^a   Alberto, Jean Marc ^a   Jeannesson, Elise ^a   Orozco Barrios, Carlos Enrique ^a,b   Martinez Fong, Daniel ^b   Daval, Jean Luc ^a   Guéant, Jean Louis ^a,c  

^a INSERM   (France)

^b DEPARTAMENTO DE FÍSICA   (Mexico)

^c OASI RESEARCH INSTITUTE IRCCS   (Italy)

Author keywords

Homocysteine; Neurotrophin

Indexed keywords

CBL PROTEIN; CYANOCOBALAMIN; HOMOCYSTEINE; LIPID; METHYLMALONIC ACID; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NERVE GROWTH FACTOR; NEUROTROPHIN RECEPTOR P75; OLEOSIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PROTEIN KINASE B; S ADENOSYLMETHIONINE; TRANSCOBALAMIN; TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BRAIN DEVELOPMENT; CATALYSIS; CELL DIFFERENTIATION; CONTROLLED STUDY; CYANOCOBALAMIN DEFICIENCY; DEMETHYLATION; GENETIC TRANSFECTION; INTRACELLULAR MEMBRANE; MOUSE; NERVE FIBER GROWTH; NEURITE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION;

ADAM PROTEINS; CELL DIFFERENTIATION; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; NERVE GROWTH FACTOR; NEUROBLASTOMA; PLASMIDS; PROTEIN PHOSPHATASE 2; PROTEIN PRECURSORS; UP-REGULATION; VITAMIN B 12 DEFICIENCY;

EID: 76049090737     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0811794106     Document Type: Article

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