Immunochemical determination of cellular prion protein in plasma from healthy subjects and patients with sporadic CJD or other neurologic diseases

Transfusion

Volumn 41, Issue 4, 2001, Pages 441-448

  Völkel, Dirk ^a,b   Zimmermann, Klaus ^a,b   Zerr, Inga ^a,b   Bodemer, Monica ^a,b   Lindner, Thomas ^a,b   Turecek, Peter L ^a,b   Poser, Sigrid ^a,b   Schwarz, Hans P ^a,b  

^a BAXTER INNOVATIONS GMBH   (Austria)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

PRION PROTEIN;

ADULT; AGED; ARTICLE; BLOOD TRANSFUSION; CLINICAL ARTICLE; CONTROLLED STUDY; CREUTZFELDT JAKOB DISEASE; DEGENERATIVE DISEASE; DIAGNOSTIC ACCURACY; DISEASE MARKER; DISEASE TRANSMISSION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLUORESCENCE; HUMAN; IMMUNOHISTOCHEMISTRY; INFECTION RISK; PLASMA TRANSFUSION; PROTEIN DETERMINATION; SCREENING; VALIDATION PROCESS;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BIOLOGICAL MARKERS; CHILD; CREUTZFELDT-JAKOB SYNDROME; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; MIDDLE AGED; NEURODEGENERATIVE DISEASES; PRIONS;

EID: 0035042157     PISSN: 00411132     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1537-2995.2001.41040441.x     Document Type: Article

References (44)

1. Descriptive epidemiology of Creutzfeldt-Jakob disease in six European countries, 1993-1995. EU collaborative study group for CJD
2. New variant Creutzfeldt-Jakob disease
3. Clinical aspects of human spongiform encephalopathies, with the exception of iatrogenic forms
4. The human prion diseases. A review with special emphasis on new variant CJD and comments on surveillance
5. Ultrastructural alterations of the vestibular nuclei in Jacob-Creutzfeld disease
6. Infectious cerebral amyloidosis: Clinical spectrum, risks and remedies
7. "Friendly fire" in medicine: Hormones, homografts, and Creutzfeldt-Jakob disease
8. Iatrogenic Creutzfeldt-Jakob disease. Lessons from cases secondary to extracted growth hormone in France
9. Self-replication and scrapie
10. Does the agent of scrapie replicate without nucleic acid?
11. Novel proteinaceous infectious particles cause scrapie
12. Scrapie prion protein contains a phosphatidylinositol glycolipid
13. Scrapie prion proteins are synthesized in neurons
14. Developmental expression of the prion protein gene in glial cells
15. A crucial role for B cells in neuroinvasive scrapie
16. Blymphocytes and neuroinvasion
17. Distribution of cell-associated prion protein in normal adult blood determined by flow cytometry
18. Increased expression of phosphatidylinositol-specific phospholipase C resistant prion proteins on the surface of activated platelets
19. Application of a time-resolved fluoroimmunoassay for the analysis of normal prion protein in human blood and its components
20. The octapeptide repeat region of prion protein binds Cu(II) in the redox-inactive state
21. Normal prion protein has an activity like that of superoxide dismutase
22. Prion protein is necessary for normal synaptic function
23. Altered circadian activity rhythms and sleep in mice devoid of prion protein
24. Degeneration of skeletal muscle, peripheral nerves, and the central nervous system in transgenic mice overexpressing wild-type prion proteins
25. Role of microglia and host prion protein in neurotoxicity of a prion protein fragment
26. Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum. Tonsil biopsy helps diagnose new variant Creutzfeldt-Jakob disease
27. Compelling transgenetic evidence for transmission of bovine spongiform encephalopathy prions to humans
28. Molecular analysis of prion strain variation and the aetiology of 'new variant' CJD
29. The same prion strain causes vCJD and BSE
30. Transmissions to mice indicate that 'new variant' CJD is caused by the BSE agent
31. Further studies of blood infectivity in an experimental model of transmissible spongiform encephalopathy, with an explanation of why blood components do not transmit Creutzfeldt-Jakob disease in humans
32. Diagnosis of Creutzfeldt-Jakob disease. Subtypes of S100 proteins must be identified
33. Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
34. 14-3-3 Protein, neuron-specific enolase, and S-100 protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
35. Diagnosis of Creutzfeldt-Jakob disease by two-dimensional gel electrophoresis of cerebrospinal fluid
36. High levels of nervous system-specific proteins in cerebrospinal fluid in patients with early stage Creutzfeldt-Jakob disease
37. The 'infecfive' process in scrapie and human spongiform encephalopathy disease
38. Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease
39. Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: Prospective case-control study
40. Mouse polyclonal and monoclonal antibody to scrapie-associated fibril proteins
41. Europium as a label in time-resolved immunofluorometric assays
42. Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease
43. Detection of 14-3-3 brain protein in the cerebrospinal fluid of patients with paraneoplastic neurological disorders
44. Prion (PrPSc)-specific epitope defined by a monoclonal antibody