Prion proteins: Physiological functions and role in neurological disorders

Journal of the Neurological Sciences

Volumn 264, Issue 1-2, 2008, Pages 1-8

  Hu, Wei ^a   Kieseier, Bernd ^b   Frohman, Elliot ^a   Eagar, Todd N ^a   Rosenberg, Roger N ^a   Hartung, Hans Peter ^b   Stüve, Olaf ^a,b,c,d  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b HEINRICH HEINE UNIVERSITY   (Germany)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^d VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

Author keywords

Adaptive immunity; Aging; Alzheimer disease; Cognition; Down syndrome; Innate immunity; Lymphocytes; Neuroprotection; Primary progressive aphasia; Prion protein; Prnp; PrP; Wilson disease

Indexed keywords

PRION PROTEIN; PRION PROTEIN[59-91]; PROTEIN BAX; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; AMINO TERMINAL SEQUENCE; ANTIGEN PRESENTING CELL; ATAXIA; B LYMPHOCYTE; BRAIN ISCHEMIA; BRAIN NERVE CELL; CD8+ T LYMPHOCYTE; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM DISEASE; CIRCADIAN RHYTHM; COGNITION; CYTOKINE PRODUCTION; DENDRITIC CELL; EXPERIMENTAL MODEL; GENE OVEREXPRESSION; GENETIC POLYMORPHISM; HOMOZYGOSITY; HUMAN; HUMORAL IMMUNITY; IMMUNE SYSTEM; LYMPHOID ORGAN; MEMORY; MEMORY CELL; MONOCYTE; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRION DISEASE; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN VARIANT; PURKINJE CELL; REVIEW; SCRAPIE; SYNAPTIC TRANSMISSION; T LYMPHOCYTE; TRANSGENE; WILSON DISEASE;

ANIMALS; BRAIN DISEASES, METABOLIC; CENTRAL NERVOUS SYSTEM; HUMANS; IMMUNE SYSTEM; IMMUNE SYSTEM DISEASES; NEURODEGENERATIVE DISEASES; PRION DISEASES; PRIONS; PRPC PROTEINS; PRPSC PROTEINS;

EID: 36549072881     PISSN: 0022510X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jns.2007.06.019     Document Type: Review

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