-
1
-
-
79957802304
-
Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine-induced parkinsonism in mice
-
1:CAS:528:DC%2BC3MXntFCrs70%3D 21419832 10.1016/j.brainresbull.2011.03. 008
-
Acuna-Castroviejo D, Tapias V, Lopez LC, Doerrier C, Camacho E, Carrion MD, Mora F, Espinosa A, Escames G (2011) Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice. Brain Res Bull 85:133-140
-
(2011)
Brain Res Bull
, vol.85
, pp. 133-140
-
-
Acuna-Castroviejo, D.1
Tapias, V.2
Lopez, L.C.3
Doerrier, C.4
Camacho, E.5
Carrion, M.D.6
Mora, F.7
Espinosa, A.8
Escames, G.9
-
2
-
-
0033977075
-
GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation
-
Betarbet R, Porter RH, Greenamyre JT (2000) GluR1 glutamate receptor subunit is regulated differentially in the primate basal ganglia following nigrostriatal dopamine denervation. J Neurochem 74:1166-1174 (Pubitemid 30104314)
-
(2000)
Journal of Neurochemistry
, vol.74
, Issue.3
, pp. 1166-1174
-
-
Betarbet, R.1
Porter, R.H.P.2
Greenamyre, J.T.3
-
3
-
-
0033540078
-
Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons
-
Bibb JA, Snyder GL, Nishi A, Yan Z, Meijer L, Fienberg AA, Tsai LH, Kwon YT, Girault JA, Czernik AJ, Huganir RL, Hemmings HC Jr, Nairn AC, Greengard P (1999) Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons. Nature 402:669-671 (Pubitemid 129516337)
-
(1999)
Nature
, vol.402
, Issue.6762
, pp. 669-671
-
-
Bibb, J.A.1
Snyder, G.L.2
Nishi, A.3
Yan, Z.4
Meijer, L.5
Fienberg, A.A.6
Tsai, L.-H.7
Kwon, Y.T.8
Girault, J.-A.9
Czernik, A.J.10
Huganlr, R.L.11
Hemmings Jr., H.C.12
Nalm, A.C.13
Greengard, P.14
-
4
-
-
27744571228
-
Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD
-
DOI 10.1016/j.expneurol.2005.08.017, PII S0014488605003171
-
Bibbiani F, Oh JD, Kielaite A, Collins MA, Smith C, Chase TN (2005) Combined blockade of AMPA and NMDA glutamate receptors reduces levodopa-induced motor complications in animal models of PD. Exp Neurol 196:422-429 (Pubitemid 41607831)
-
(2005)
Experimental Neurology
, vol.196
, Issue.2
, pp. 422-429
-
-
Bibbiani, F.1
Oh, J.D.2
Kielaite, A.3
Collins, M.A.4
Smith, C.5
Chase, T.N.6
-
5
-
-
0023809607
-
Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors
-
1:CAS:528:DyaL1cXls1CjsLk%3D 2901972 10.1016/0014-2999(88)90814-X
-
Birch PJ, Grossman CJ, Hayes AG (1988) Kynurenate and FG9041 have both competitive and non-competitive antagonist actions at excitatory amino acid receptors. Eur J Pharmacol 151:313-315
-
(1988)
Eur J Pharmacol
, vol.151
, pp. 313-315
-
-
Birch, P.J.1
Grossman, C.J.2
Hayes, A.G.3
-
6
-
-
77957664714
-
An update on the potential role of excitotoxicity in the pathogenesis of Parkinson's disease
-
20923603 10.1016/S0213-4853(10)70027-X
-
Blandini F (2010) An update on the potential role of excitotoxicity in the pathogenesis of Parkinson's disease. Funct Neurol 25:65-71
-
(2010)
Funct Neurol
, vol.25
, pp. 65-71
-
-
Blandini, F.1
-
7
-
-
0037333666
-
Staging of brain pathology related to sporadic Parkinson's disease
-
DOI 10.1016/S0197-4580(02)00065-9, PII S0197458002000659
-
Braak H, Del Tredici K, Rub U, de Vos RA, Jansen Steur EN, Braak E (2003) Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging 24:197-211 (Pubitemid 36007810)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.2
, pp. 197-211
-
-
Braak, H.1
Del Tredici, K.2
Rub, U.3
De Vos, R.A.I.4
Jansen Steur, E.N.H.5
Braak, E.6
-
8
-
-
0025845919
-
Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate
-
1:STN:280:DyaK3M3nvVyqsQ%3D%3D 1647492 10.1002/mds.870060208
-
Brotchie JM, Mitchell IJ, Sambrook MA, Crossman AR (1991) Alleviation of parkinsonism by antagonism of excitatory amino acid transmission in the medial segment of the globus pallidus in rat and primate. Mov Disord 6:133-138
-
(1991)
Mov Disord
, vol.6
, pp. 133-138
-
-
Brotchie, J.M.1
Mitchell, I.J.2
Sambrook, M.A.3
Crossman, A.R.4
-
9
-
-
0026526276
-
Long-term synaptic depression in the striatum: Physiological and pharmacological characterization
-
1:CAS:528:DyaK3sXhs1Orsw%3D%3D 1359031
-
Calabresi P, Maj R, Pisani A, Mercuri NB, Bernardi G (1992) Long-term synaptic depression in the striatum: physiological and pharmacological characterization. J Neurosci 12:4224-4233
-
(1992)
J Neurosci
, vol.12
, pp. 4224-4233
-
-
Calabresi, P.1
Maj, R.2
Pisani, A.3
Mercuri, N.B.4
Bernardi, G.5
-
10
-
-
0030919907
-
Abnormal synaptic plasticity in the striatum of mice lacking dopamine D2 receptors
-
Calabresi P, Saiardi A, Pisani A, Baik JH, Centonze D, Mercuri NB, Bernardi G, Borrelli E (1997) Abnormal synaptic plasticity in the striatum of mice lacking dopamine D2 receptors. J Neurosci 17:4536-4544 (Pubitemid 27246911)
-
(1997)
Journal of Neuroscience
, vol.17
, Issue.12
, pp. 4536-4544
-
-
Calabresi, P.1
Saiardi, A.2
Pisani, A.3
Baik, J.-H.4
Centonze, D.5
Mercuri, N.B.6
Bernardi, G.7
Borrelli, E.8
-
11
-
-
71549151931
-
Glutamate, excitotoxicity, and programmed cell death in Parkinson disease
-
1:CAS:528:DC%2BD1MXhsVGnt7zP 19815009 10.1016/j.expneurol.2009.09.027
-
Caudle WM, Zhang J (2009) Glutamate, excitotoxicity, and programmed cell death in Parkinson disease. Exp Neurol 220:230-233
-
(2009)
Exp Neurol
, vol.220
, pp. 230-233
-
-
Caudle, W.M.1
Zhang, J.2
-
12
-
-
34047114733
-
Dopamine dysregulation of movement control in l-DOPA-induced dyskinesia
-
DOI 10.1016/j.tins.2007.03.005, PII S0166223607000665, Fifty years of dopamine research
-
Cenci MA (2007) Dopamine dysregulation of movement control in L-DOPA-induced dyskinesia. Trends Neurosci 30:236-243 (Pubitemid 46654236)
-
(2007)
Trends in Neurosciences
, vol.30
, Issue.5
, pp. 236-243
-
-
Cenci, M.A.1
-
13
-
-
0035124718
-
2 dopamine receptor-deficient mice
-
Cepeda C, Hurst RS, Altemus KL, Flores-Hernandez J, Calvert CR, Jokel ES, Grandy DK, Low MJ, Rubinstein M, Ariano MA, Levine MS (2001) Facilitated glutamatergic transmission in the striatum of D2 dopamine receptor-deficient mice. J Neurophysiol 85:659-670 (Pubitemid 32147768)
-
(2001)
Journal of Neurophysiology
, vol.85
, Issue.2
, pp. 659-670
-
-
Cepeda, C.1
Hurst, R.S.2
Altemus, K.L.3
Flores-Hernandez, J.4
Calvert, C.R.5
Jokel, E.S.6
Grandy, D.K.7
Low, M.J.8
Rubinstein, M.9
Ariano, M.A.10
Levine, M.S.11
-
14
-
-
3843069965
-
1 receptor functional hypersensitivity in Parkinson disease
-
DOI 10.1523/JNEUROSCI.0676-04.2004
-
Corvol JC, Muriel MP, Valjent E, Feger J, Hanoun N, Girault JA, Hirsch EC, Herve D (2004) Persistent increase in olfactory type G-protein alpha subunit levels may underlie D1 receptor functional hypersensitivity in Parkinson disease. J Neurosci 24:7007-7014 (Pubitemid 39045457)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.31
, pp. 7007-7014
-
-
Corvol, J.-C.1
Muriel, M.-P.2
Valjent, E.3
Feger, J.4
Hanoun, N.5
Girault, J.-A.6
Hirsch, E.C.7
Herve, D.8
-
15
-
-
0030759545
-
The regulation of motor control: An evaluation of the role of dopamine receptors in the substantia nigra
-
Crocker AD (1997) The regulation of motor control: an evaluation of the role of dopamine receptors in the substantia nigra. Rev Neurosci 8:55-76 (Pubitemid 27354658)
-
(1997)
Reviews in the Neurosciences
, vol.8
, Issue.1
, pp. 55-76
-
-
Crocker, A.D.1
-
16
-
-
0034643838
-
Prevalence of Parkinson's disease in Europe: A collaborative study of population-based cohorts. Neurologic diseases in the elderly research group
-
10854357
-
de Rijk MC, Launer LJ, Berger K, Breteler MM, Dartigues JF, Baldereschi M, Fratiglioni L, Lobo A, Martinez-Lage J, Trenkwalder C, Hofman A (2000) Prevalence of Parkinson's disease in Europe: a collaborative study of population-based cohorts. Neurologic diseases in the elderly research group. Neurology 54:S21-S23
-
(2000)
Neurology
, vol.54
-
-
De Rijk, M.C.1
Launer, L.J.2
Berger, K.3
Breteler, M.M.4
Dartigues, J.F.5
Baldereschi, M.6
Fratiglioni, L.7
Lobo, A.8
Martinez-Lage, J.9
Trenkwalder, C.10
Hofman, A.11
-
17
-
-
0029998572
-
Dual character, asynaptic and synaptic, of the dopamine innervation in adult rat neostriatum: A quantitative autoradiographic and immunocytochemical analysis
-
DOI 10.1002/(SICI)1096-9861(19961111)375:2<167::AID-CNE1>3.0.CO;2-0
-
Descarries L, Watkins KC, Garcia S, Bosler O, Doucet G (1996) Dual character, asynaptic and synaptic, of the dopamine innervation in adult rat neostriatum: a quantitative autoradiographic and immunocytochemical analysis. J Comp Neurol 375:167-186 (Pubitemid 26378130)
-
(1996)
Journal of Comparative Neurology
, vol.375
, Issue.2
, pp. 167-186
-
-
Descarries, L.1
Watkins, K.C.2
Garcia, S.3
Bosler, O.4
Doucet, G.5
-
18
-
-
0028937650
-
Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain
-
1:CAS:528:DyaK2MXks1ejtrc%3D 7609872 10.1016/0306-4522(94)00527-C
-
Diaz J, Levesque D, Lammers CH, Griffon N, Martres MP, Schwartz JC, Sokoloff P (1995) Phenotypical characterization of neurons expressing the dopamine D3 receptor in the rat brain. Neuroscience 65:731-745
-
(1995)
Neuroscience
, vol.65
, pp. 731-745
-
-
Diaz, J.1
Levesque, D.2
Lammers, C.H.3
Griffon, N.4
Martres, M.P.5
Schwartz, J.C.6
Sokoloff, P.7
-
19
-
-
4043156932
-
Dopamine dysregulation syndrome in Parkinson's disease
-
DOI 10.1097/01.wco.0000137528.23126.41
-
Evans AH, Lees AJ (2004) Dopamine dysregulation syndrome in Parkinson's disease. Curr Opin Neurol 17:393-398 (Pubitemid 39071414)
-
(2004)
Current Opinion in Neurology
, vol.17
, Issue.4
, pp. 393-398
-
-
Evans, A.H.1
Lees, A.J.2
-
20
-
-
2342442360
-
Punding in Parkinson's disease: Its relation to the dopamine dysregulation syndrome
-
DOI 10.1002/mds.20045
-
Evans AH, Katzenschlager R, Paviour D, O'Sullivan JD, Appel S, Lawrence AD, Lees AJ (2004) Punding in Parkinson's disease: its relation to the dopamine dysregulation syndrome. Mov Disord 19:397-405 (Pubitemid 38559642)
-
(2004)
Movement Disorders
, vol.19
, Issue.4
, pp. 397-405
-
-
Evans, A.H.1
Katzenschlager, R.2
Paviour, D.3
O'Sullivan, J.D.4
Appel, S.5
Lawrence, A.D.6
Lees, A.J.7
-
21
-
-
34548495566
-
Signaling in the basal ganglia: Postsynaptic and presynaptic mechanisms
-
DOI 10.1016/j.physbeh.2007.05.028, PII S0031938407002211
-
Fisone G, Hakansson K, Borgkvist A, Santini E (2007) Signaling in the basal ganglia: postsynaptic and presynaptic mechanisms. Physiol Behav 92:8-14 (Pubitemid 47376895)
-
(2007)
Physiology and Behavior
, vol.92
, Issue.1-2
, pp. 8-14
-
-
Fisone, G.1
Hakansson, K.2
Borgkvist, A.3
Santini, E.4
-
22
-
-
71949108894
-
Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives
-
1:CAS:528:DC%2BC3cXhsVSmtr8%3D 19929784 10.2174/092986709789909602
-
Fulop F, Szatmari I, Vamos E, Zadori D, Toldi J, Vecsei L (2009) Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives. Curr Med Chem 16:4828-4842
-
(2009)
Curr Med Chem
, vol.16
, pp. 4828-4842
-
-
Fulop, F.1
Szatmari, I.2
Vamos, E.3
Zadori, D.4
Toldi, J.5
Vecsei, L.6
-
23
-
-
79955777922
-
Addiction and brain reward and antireward pathways
-
21508625 10.1159/000324065
-
Gardner EL (2011) Addiction and brain reward and antireward pathways. Adv Psychosom Med 30:22-60
-
(2011)
Adv Psychosom Med
, vol.30
, pp. 22-60
-
-
Gardner, E.L.1
-
24
-
-
79959869606
-
Modulation of striatal projection systems by dopamine
-
1:CAS:528:DC%2BC3MXpvVyisrk%3D 21469956 10.1146/annurev-neuro-061010- 113641
-
Gerfen CR, Surmeier DJ (2011) Modulation of striatal projection systems by dopamine. Annu Rev Neurosci 34:441-466
-
(2011)
Annu Rev Neurosci
, vol.34
, pp. 441-466
-
-
Gerfen, C.R.1
Surmeier, D.J.2
-
25
-
-
0142091254
-
Dopamine receptor agonists in current clinical use: Comparative dopamine receptor binding profiles defined in the human striatum
-
DOI 10.1007/s00702-003-0027-5
-
Gerlach M, Double K, Arzberger T, Leblhuber F, Tatschner T, Riederer P (2003) Dopamine receptor agonists in current clinical use: comparative dopamine receptor binding profiles defined in the human striatum. J Neural Transm 110:1119-1127 (Pubitemid 37271855)
-
(2003)
Journal of Neural Transmission
, vol.110
, Issue.10
, pp. 1119-1127
-
-
Gerlach, M.1
Double, K.2
Arzberger, T.3
Leblhuber, F.4
Tatschner, T.5
Riederer, P.6
-
26
-
-
0034055187
-
Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies
-
DOI 10.1136/jnnp.68.4.423
-
Giovannoni G, O'Sullivan JD, Turner K, Manson AJ, Lees AJ (2000) Hedonistic homeostatic dysregulation in patients with Parkinson's disease on dopamine replacement therapies. J Neurol Neurosurg Psychiatry 68:423-428 (Pubitemid 30248740)
-
(2000)
Journal of Neurology Neurosurgery and Psychiatry
, vol.68
, Issue.4
, pp. 423-428
-
-
Giovannoni, G.1
O'Sullivan, J.D.2
Turner, K.3
Manson, A.J.4
Lees, A.J.L.5
-
27
-
-
84858130166
-
Integrating neurotransmission in striatal medium spiny neurons
-
1:CAS:528:DC%2BC38XhvVajsrrM 22351066 10.1007/978-3-7091-0932-8-18
-
Girault JA (2012) Integrating neurotransmission in striatal medium spiny neurons. Adv Exp Med Biol 970:407-429
-
(2012)
Adv Exp Med Biol
, vol.970
, pp. 407-429
-
-
Girault, J.A.1
-
28
-
-
0020514306
-
Intracellular and extracellular electrophysiology of nigral dopaminergic neurons. 2. Action potential generating mechanisms and morphologic correlates
-
DOI 10.1016/0306-4522(83)90136-7
-
Grace AA, Bunney BS (1983) Intracellular and extracellular electrophysiology of nigral dopaminergic neurons-2. Action potential generating mechanisms and morphological correlates. Neuroscience 10:317-331 (Pubitemid 13019571)
-
(1983)
Neuroscience
, vol.10
, Issue.2
, pp. 317-331
-
-
Grace, A.A.1
Bunney, B.S.2
-
29
-
-
0021718376
-
The control of firing pattern in nigral dopamine neurons: Burst firing
-
Grace AA, Bunney BS (1984a) The control of firing pattern in nigral dopamine neurons: burst firing. J Neurosci 4:2877-2890 (Pubitemid 15224432)
-
(1984)
Journal of Neuroscience
, vol.4
, Issue.11
, pp. 2877-2890
-
-
Grace, A.A.1
Bunney, B.S.2
-
30
-
-
0021714346
-
The control of firing pattern in nigral dopamine neurons: Single spike firing
-
Grace AA, Bunney BS (1984b) The control of firing pattern in nigral dopamine neurons: single spike firing. J Neurosci 4:2866-2876 (Pubitemid 15224431)
-
(1984)
Journal of Neuroscience
, vol.4
, Issue.11
, pp. 2866-2876
-
-
Grace, A.A.1
Bunney, B.S.2
-
31
-
-
17144446935
-
Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism
-
1:STN:280:DyaK3M%2Fms1OhsA%3D%3D 2250573 10.1016/0024-3205(90)90376-3
-
Graham WC, Robertson RG, Sambrook MA, Crossman AR (1990) Injection of excitatory amino acid antagonists into the medial pallidal segment of a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treated primate reverses motor symptoms of parkinsonism. Life Sci 47:PL91-PL97
-
(1990)
Life Sci
, vol.47
-
-
Graham, W.C.1
Robertson, R.G.2
Sambrook, M.A.3
Crossman, A.R.4
-
32
-
-
36248936617
-
Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys
-
DOI 10.1016/j.bbr.2007.08.007, PII S0166432807004068
-
Gregoire L, Rassoulpour A, Guidetti P, Samadi P, Bedard PJ, Izzo E, Schwarcz R, Di Paolo T (2008) Prolonged kynurenine 3-hydroxylase inhibition reduces development of levodopa-induced dyskinesias in parkinsonian monkeys. Behav Brain Res 186:161-167 (Pubitemid 350122751)
-
(2008)
Behavioural Brain Research
, vol.186
, Issue.2
, pp. 161-167
-
-
Gregoire, L.1
Rassoulpour, A.2
Guidetti, P.3
Samadi, P.4
Bedard, P.J.5
Izzo, E.6
Schwarcz, R.7
Di Paolo, T.8
-
33
-
-
0025129228
-
Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices
-
DOI 10.1038/343369a0
-
Halpain S, Girault JA, Greengard P (1990) Activation of NMDA receptors induces dephosphorylation of DARPP-32 in rat striatal slices. Nature 343:369-372 (Pubitemid 20032854)
-
(1990)
Nature
, vol.343
, Issue.6256
, pp. 369-372
-
-
Halpain, S.1
Girault, J.-A.2
Greengard, P.3
-
34
-
-
0031836667
-
Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid
-
DOI 10.1038/sj.bjp.0701834
-
Harris CA, Miranda AF, Tanguay JJ, Boegman RJ, Beninger RJ, Jhamandas K (1998) Modulation of striatal quinolinate neurotoxicity by elevation of endogenous brain kynurenic acid. Br J Pharmacol 124:391-399 (Pubitemid 28248031)
-
(1998)
British Journal of Pharmacology
, vol.124
, Issue.2
, pp. 391-399
-
-
Harris, C.A.1
Miranda, A.F.2
Tanguay, J.J.3
Boegman, R.J.4
Beninger, R.J.5
Jhamandas, K.6
-
35
-
-
33644857867
-
Dopaminergic and GABAergic modulation of glutamate release from rat subthalamic nucleus efferents to the substantia nigra
-
DOI 10.1016/j.brainres.2006.01.015, PII S0006899306000813
-
Hatzipetros T, Yamamoto BK (2006) Dopaminergic and GABAergic modulation of glutamate release from rat subthalamic nucleus efferents to the substantia nigra. Brain Res 1076:60-67 (Pubitemid 43376023)
-
(2006)
Brain Research
, vol.1076
, Issue.1
, pp. 60-67
-
-
Hatzipetros, T.1
Yamamoto, B.K.2
-
36
-
-
0021162349
-
DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1
-
Hemmings HC Jr, Greengard P, Tung HY, Cohen P (1984) DARPP-32, a dopamine-regulated neuronal phosphoprotein, is a potent inhibitor of protein phosphatase-1. Nature 310:503-505 (Pubitemid 14052413)
-
(1984)
Nature
, vol.310
, Issue.5977
, pp. 503-505
-
-
Hemmings Jr., H.C.1
Greengard, P.2
Lim Tung, H.Y.3
Cohen, P.4
-
37
-
-
0035478066
-
The brain metabolite kynurenic acid inhibits α7 nicotinic receptor activity and increases non-α7 nicotinic receptor expression: Physiopathological implications
-
Hilmas C, Pereira EF, Alkondon M, Rassoulpour A, Schwarcz R, Albuquerque EX (2001) The brain metabolite kynurenic acid inhibits alpha7 nicotinic receptor activity and increases non-alpha7 nicotinic receptor expression: physiopathological implications. J Neurosci 21:7463-7473 (Pubitemid 32904945)
-
(2001)
Journal of Neuroscience
, vol.21
, Issue.19
, pp. 7463-7473
-
-
Hilmas, C.1
Pereira, E.F.R.2
Alkondon, M.3
Rassoulpour, A.4
Schwarcz, R.5
Albuquerque, E.X.6
-
38
-
-
0011866822
-
7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-d-aspartate receptor complex
-
1:CAS:528:DyaL1cXls1CjtrY%3D 2842779 10.1073/pnas.85.17.6547
-
Kemp JA, Foster AC, Leeson PD, Priestley T, Tridgett R, Iversen LL, Woodruff GN (1988) 7-Chlorokynurenic acid is a selective antagonist at the glycine modulatory site of the N-methyl-d-aspartate receptor complex. Proc Natl Acad Sci USA 85:6547-6550
-
(1988)
Proc Natl Acad Sci USA
, vol.85
, pp. 6547-6550
-
-
Kemp, J.A.1
Foster, A.C.2
Leeson, P.D.3
Priestley, T.4
Tridgett, R.5
Iversen, L.L.6
Woodruff, G.N.7
-
39
-
-
0024564076
-
A glycine site associated with N-methyl-D-aspartic acid receptors: Characterization and identification of a new class of antagonists
-
DOI 10.1111/j.1471-4159.1989.tb01881.x
-
Kessler M, Terramani T, Lynch G, Baudry M (1989) A glycine site associated with N-methyl-d-aspartic acid receptors: characterization and identification of a new class of antagonists. J Neurochem 52:1319-1328 (Pubitemid 19085960)
-
(1989)
Journal of Neurochemistry
, vol.52
, Issue.4
, pp. 1319-1328
-
-
Kessler, M.1
Terramani, T.2
Lynch, G.3
Baudry, M.4
-
40
-
-
17944399946
-
Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) treatment
-
DOI 10.1016/j.neuroscience.2004.04.043, PII S0306452204003173
-
Knyihar-Csillik E, Csillik B, Pakaski M, Krisztin-Peva B, Dobo E, Okuno E, Vecsei L (2004) Decreased expression of kynurenine aminotransferase-I (KAT-I) in the substantia nigra of mice after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine (MPTP) treatment. Neuroscience 126:899-914 (Pubitemid 38780895)
-
(2004)
Neuroscience
, vol.126
, Issue.4
, pp. 899-914
-
-
Knyihar-Csillik, E.1
Csillik, B.2
Pakaski, M.3
Krisztin-Peva, B.4
Dobo, E.5
Okuno, E.6
Vecsei, L.7
-
41
-
-
39049186145
-
Effect of 6-hydroxydopamine treatment on kynurenine aminotransferase-I (KAT-I) immunoreactivity of neurons and glial cells in the rat substantia nigra
-
1:CAS:528:DC%2BD28Xnt1yju7Y%3D 16788821 10.1007/s00401-006-0086-4
-
Knyihar-Csillik E, Chadaide Z, Mihaly A, Krisztin-Peva B, Fenyo R, Vecsei L (2006) Effect of 6-hydroxydopamine treatment on kynurenine aminotransferase-I (KAT-I) immunoreactivity of neurons and glial cells in the rat substantia nigra. Acta Neuropathol 112:127-137
-
(2006)
Acta Neuropathol
, vol.112
, pp. 127-137
-
-
Knyihar-Csillik, E.1
Chadaide, Z.2
Mihaly, A.3
Krisztin-Peva, B.4
Fenyo, R.5
Vecsei, L.6
-
42
-
-
0034090891
-
AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys
-
Konitsiotis S, Blanchet PJ, Verhagen L, Lamers E, Chase TN (2000) AMPA receptor blockade improves levodopa-induced dyskinesia in MPTP monkeys. Neurology 54:1589-1595 (Pubitemid 30226801)
-
(2000)
Neurology
, vol.54
, Issue.8
, pp. 1589-1595
-
-
Konitsiotis, S.1
Blanchet, P.J.2
Verhagen, L.3
Lamers, E.4
Chase, T.N.5
-
43
-
-
44549089063
-
Kynurenic acid attenuates MPP(+)-induced dopaminergic neuronal cell death via a Bax-mediated mitochondrial pathway
-
18462830 10.1016/j.ejcb.2008.03.003 1:CAS:528:DC%2BD1cXpslOjtro%3D
-
Lee do Y, Lee KS, Lee HJ, Noh YH, Kim do H, Lee YJ, Cho SH, Yoon OJ, Lee WB, Kim KY, Chung YH, Kim SS (2008) Kynurenic acid attenuates MPP(+)-induced dopaminergic neuronal cell death via a Bax-mediated mitochondrial pathway. Eur J Cell Biol 87:389-397
-
(2008)
Eur J Cell Biol
, vol.87
, pp. 389-397
-
-
Lee Do, Y.1
Lee, K.S.2
Lee, H.J.3
Noh, Y.H.4
Kim Do, H.5
Lee, Y.J.6
Cho, S.H.7
Yoon, O.J.8
Lee, W.B.9
Kim, K.Y.10
Chung, Y.H.11
Kim, S.S.12
-
44
-
-
70450044450
-
Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinson's disease
-
19562769 10.1002/mds.22678
-
Lee JY, Lee EK, Park SS, Lim JY, Kim HJ, Kim JS, Jeon BS (2009) Association of DRD3 and GRIN2B with impulse control and related behaviors in Parkinson's disease. Mov Disord 24:1803-1810
-
(2009)
Mov Disord
, vol.24
, pp. 1803-1810
-
-
Lee, J.Y.1
Lee, E.K.2
Park, S.S.3
Lim, J.Y.4
Kim, H.J.5
Kim, J.S.6
Jeon, B.S.7
-
45
-
-
0345451050
-
Modulation of rat striatal glutamatergic response in search for new neuroprotective agents: Evaluation of melatonin and some kynurenine derivatives
-
DOI 10.1016/S0361-9230(97)00440-1, PII S0361923097004401
-
Leon J, Vives F, Gomez I, Camacho E, Gallo MA, Espinosa A, Escames G, Acuna-Castroviejo D (1998) Modulation of rat striatal glutamatergic response in search for new neuroprotective agents: evaluation of melatonin and some kynurenine derivatives. Brain Res Bull 45:525-530 (Pubitemid 28188545)
-
(1998)
Brain Research Bulletin
, vol.45
, Issue.5
, pp. 525-530
-
-
Leon, J.1
Vives, F.2
Gomez, I.3
Camacho, E.4
Gallo, M.A.5
Espinosa, A.6
Escames, G.7
Acuna-Castroviejo, D.8
-
46
-
-
0030911620
-
Cyclic AMP-dependent protein kinase and protein kinase C phosphorylate N-methyl-D-aspartate receptors at different sites
-
DOI 10.1074/jbc.272.18.12107
-
Leonard AS, Hell JW (1997) Cyclic AMP-dependent protein kinase and protein kinase C phosphorylate N-methyl-d-aspartate receptors at different sites. J Biol Chem 272:12107-12115 (Pubitemid 27202791)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.18
, pp. 12107-12115
-
-
Leonard, A.S.1
Hell, J.W.2
-
47
-
-
55049085702
-
Impulse control and related disorders in Parkinson's disease: Review
-
1:CAS:528:DC%2BD1cXhsV2hsb7N 18990123 10.1196/annals.1444.006
-
Lim SY, Evans AH, Miyasaki JM (2008) Impulse control and related disorders in Parkinson's disease: review. Ann N Y Acad Sci 1142:85-107
-
(2008)
Ann N y Acad Sci
, vol.1142
, pp. 85-107
-
-
Lim, S.Y.1
Evans, A.H.2
Miyasaki, J.M.3
-
48
-
-
0030915272
-
Neurotoxicity associated with dual actions of homocysteine at the N- methyl-D-aspartate receptor
-
DOI 10.1073/pnas.94.11.5923
-
Lipton SA, Kim WK, Choi YB, Kumar S, D'Emilia DM, Rayudu PV, Arnelle DR, Stamler JS (1997) Neurotoxicity associated with dual actions of homocysteine at the N-methyl-d-aspartate receptor. Proc Natl Acad Sci USA 94:5923-5928 (Pubitemid 27241873)
-
(1997)
Proceedings of the National Academy of Sciences of the United States of America
, vol.94
, Issue.11
, pp. 5923-5928
-
-
Lipton, S.A.1
Kim, W.-K.2
Choi, Y.-B.3
Kumar, S.4
D'Emilia, D.M.5
Rayudu, P.V.6
Arnell, D.R.7
Stamler, J.S.8
-
49
-
-
0037072547
-
1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats
-
DOI 10.1016/S0304-3940(02)00735-8, PII S0304394002007358
-
Luchowski P, Luchowska E, Turski WA, Urbanska EM (2002) 1-Methyl-4-phenylpyridinium and 3-nitropropionic acid diminish cortical synthesis of kynurenic acid via interference with kynurenine aminotransferases in rats. Neurosci Lett 330:49-52 (Pubitemid 35245767)
-
(2002)
Neuroscience Letters
, vol.330
, Issue.1
, pp. 49-52
-
-
Luchowski, P.1
Luchowska, E.2
Turski, W.A.3
Urbanska, E.M.4
-
50
-
-
77249133018
-
A novel kynurenic acid analogue: A comparison with kynurenic acid. An in vitro electrophysiological study
-
1:CAS:528:DC%2BC3cXpslWjtg%3D%3D 19953278 10.1007/s00702-009-0346-2
-
Marosi M, Nagy D, Farkas T, Kis Z, Rozsa E, Robotka H, Fulop F, Vecsei L, Toldi J (2010) A novel kynurenic acid analogue: a comparison with kynurenic acid. An in vitro electrophysiological study. J Neural Transm 117:183-188
-
(2010)
J Neural Transm
, vol.117
, pp. 183-188
-
-
Marosi, M.1
Nagy, D.2
Farkas, T.3
Kis, Z.4
Rozsa, E.5
Robotka, H.6
Fulop, F.7
Vecsei, L.8
Toldi, J.9
-
51
-
-
34249796691
-
Homocysteine and Parkinson's disease: A dangerous liaison?
-
DOI 10.1016/j.jns.2007.01.028, PII S0022510X07000548, Vascular Dementia Proceedings of the Fourth International Congress on Vascular Dementia
-
Martignoni E, Tassorelli C, Nappi G, Zangaglia R, Pacchetti C, Blandini F (2007) Homocysteine and Parkinson's disease: a dangerous liaison? J Neurol Sci 257:31-37 (Pubitemid 46856499)
-
(2007)
Journal of the Neurological Sciences
, vol.257
, Issue.1-2
, pp. 31-37
-
-
Martignoni, E.1
Tassorelli, C.2
Nappi, G.3
Zangaglia, R.4
Pacchetti, C.5
Blandini, F.6
-
52
-
-
0031105375
-
Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease
-
DOI 10.1006/exnr.1997.6418
-
McRitchie DA, Cartwright HR, Halliday GM (1997) Specific A10 dopaminergic nuclei in the midbrain degenerate in Parkinson's disease. Exp Neurol 144:202-213 (Pubitemid 27149624)
-
(1997)
Experimental Neurology
, vol.144
, Issue.1
, pp. 202-213
-
-
McRitchie, D.A.1
Cartwright, H.R.2
Halliday, G.M.3
-
53
-
-
0034302416
-
The personality associated with Parkinson's disease
-
1:STN:280:DC%2BD3MvkslSnsw%3D%3D 11122991 10.1007/s11920-000-0027-1
-
Menza M (2000) The personality associated with Parkinson's disease. Curr Psychiatry Rep 2:421-426
-
(2000)
Curr Psychiatry Rep
, vol.2
, pp. 421-426
-
-
Menza, M.1
-
54
-
-
68749114987
-
Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease
-
1:CAS:528:DC%2BD1MXpvF2mur4%3D 19523952 10.1016/j.expneurol.2009.06.005
-
Meredith GE, Totterdell S, Beales M, Meshul CK (2009) Impaired glutamate homeostasis and programmed cell death in a chronic MPTP mouse model of Parkinson's disease. Exp Neurol 219:334-340
-
(2009)
Exp Neurol
, vol.219
, pp. 334-340
-
-
Meredith, G.E.1
Totterdell, S.2
Beales, M.3
Meshul, C.K.4
-
55
-
-
0032778037
-
+
-
DOI 10.1046/j.1471-4159.1999.0730750.x
-
Merino M, Vizuete ML, Cano J, Machado A (1999) The non-NMDA glutamate receptor antagonists 6-cyano-7-nitroquinoxaline-2,3-dione and 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline, but not NMDA antagonists, block the intrastriatal neurotoxic effect of MPP+. J Neurochem 73:750-757 (Pubitemid 29339850)
-
(1999)
Journal of Neurochemistry
, vol.73
, Issue.2
, pp. 750-757
-
-
Merino, M.1
Vizuete, M.L.2
Cano, J.3
Machado, A.4
-
56
-
-
0026497479
-
The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations
-
1:CAS:528:DyaK38XmsVGnur0%3D 1475044 10.1016/0304-3940(92)90186-B
-
Miller JM, MacGarvey U, Beal MF (1992) The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations. Neurosci Lett 146:115-118
-
(1992)
Neurosci Lett
, vol.146
, pp. 115-118
-
-
Miller, J.M.1
Macgarvey, U.2
Beal, M.F.3
-
57
-
-
0030956088
-
Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid
-
DOI 10.1016/S0306-4522(96)00655-0, PII S0306452296006550
-
Miranda AF, Boegman RJ, Beninger RJ, Jhamandas K (1997) Protection against quinolinic acid-mediated excitotoxicity in nigrostriatal dopaminergic neurons by endogenous kynurenic acid. Neuroscience 78:967-975 (Pubitemid 27223703)
-
(1997)
Neuroscience
, vol.78
, Issue.4
, pp. 967-975
-
-
Miranda, A.F.1
Boegman, R.J.2
Beninger, R.J.3
Jhamandas, K.4
-
58
-
-
5444258474
-
Innervation of the substantia nigra
-
DOI 10.1007/s00441-004-0918-2
-
Misgeld U (2004) Innervation of the substantia nigra. Cell Tissue Res 318:107-114 (Pubitemid 39362631)
-
(2004)
Cell and Tissue Research
, vol.318
, Issue.1
, pp. 107-114
-
-
Misgeld, U.1
-
59
-
-
50949117770
-
Dopaminergic neuron-specific oxidative stress caused by dopamine itself
-
1:CAS:528:DC%2BD1cXovFOht7c%3D 18596830
-
Miyazaki I, Asanuma M (2008) Dopaminergic neuron-specific oxidative stress caused by dopamine itself. Acta Med Okayama 62:141-150
-
(2008)
Acta Med Okayama
, vol.62
, pp. 141-150
-
-
Miyazaki, I.1
Asanuma, M.2
-
60
-
-
77950958966
-
Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys
-
1:CAS:528:DC%2BC3cXksVektrc%3D 20074579 10.1016/j.neuropharm.2009.12.024
-
Morin N, Gregoire L, Gomez-Mancilla B, Gasparini F, Di Paolo T (2010) Effect of the metabotropic glutamate receptor type 5 antagonists MPEP and MTEP in parkinsonian monkeys. Neuropharmacology 58:981-986
-
(2010)
Neuropharmacology
, vol.58
, pp. 981-986
-
-
Morin, N.1
Gregoire, L.2
Gomez-Mancilla, B.3
Gasparini, F.4
Di Paolo, T.5
-
61
-
-
78649386112
-
Catechol-O-methyltransferase enzyme: Cofactor S-adenosyl-l-methionine and related mechanisms
-
21095459 10.1016/B978-0-12-381326-8.00004-1 1:CAS:528: DC%2BC3MXovFSmsA%3D%3D
-
Muller T (2010) Catechol-O-methyltransferase enzyme: cofactor S-adenosyl-l-methionine and related mechanisms. Int Rev Neurobiol 95:49-71
-
(2010)
Int Rev Neurobiol
, vol.95
, pp. 49-71
-
-
Muller, T.1
-
62
-
-
34447278346
-
Neurotoxicity of levodopa: Treatment-associated homocysteine increase
-
17549055 10.1038/ncpneuro0527
-
Muller T, Kuhn W (2007) Neurotoxicity of levodopa: treatment-associated homocysteine increase. Nat Clin Pract Neurol 3:E1
-
(2007)
Nat Clin Pract Neurol
, vol.3
, pp. 1
-
-
Muller, T.1
Kuhn, W.2
-
63
-
-
79953271910
-
Cysteinyl-glycine reduction as marker for levodopa-induced oxidative stress in Parkinson's disease patients
-
21462263 10.1002/mds.23384
-
Muller T, Muhlack S (2011) Cysteinyl-glycine reduction as marker for levodopa-induced oxidative stress in Parkinson's disease patients. Mov Disord 26:543-546
-
(2011)
Mov Disord
, vol.26
, pp. 543-546
-
-
Muller, T.1
Muhlack, S.2
-
64
-
-
84862599656
-
Cysteine decrease following acute Levodopa intake in patients with Parkinson's disease
-
22641055 10.1016/j.neulet.2012.05.054 1:CAS:528:DC%2BC38XoslGmu7c%3D
-
Muller T, Muhlack S (2012) Cysteine decrease following acute Levodopa intake in patients with Parkinson's disease. Neurosci Lett 521:37-39
-
(2012)
Neurosci Lett
, vol.521
, pp. 37-39
-
-
Muller, T.1
Muhlack, S.2
-
65
-
-
5644240981
-
Is levodopa toxic?
-
Muller T, Hefter H, Hueber R, Jost WH, Leenders KL, Odin P, Schwarz J (2004) Is levodopa toxic? J Neurol 251(Suppl 6):VI/44-VI/46
-
(2004)
J Neurol
, vol.251
, Issue.SUPPL. 6
-
-
Muller, T.1
Hefter, H.2
Hueber, R.3
Jost, W.H.4
Leenders, K.L.5
Odin, P.6
Schwarz, J.7
-
66
-
-
0023895734
-
Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced
-
1:CAS:528:DyaL1cXktlentLo%3D 2472189 10.1016/0006-8993(88)90765-2
-
Novelli A, Reilly JA, Lysko PG, Henneberry RC (1988) Glutamate becomes neurotoxic via the N-methyl-d-aspartate receptor when intracellular energy levels are reduced. Brain Res 451:205-212
-
(1988)
Brain Res
, vol.451
, pp. 205-212
-
-
Novelli, A.1
Reilly, J.A.2
Lysko, P.G.3
Henneberry, R.C.4
-
67
-
-
0026671306
-
Kynurenine pathway abnormalities in Parkinson's disease
-
1:CAS:528:DyaK3sXnvVGhsQ%3D%3D 1513457 10.1212/WNL.42.9.1702
-
Ogawa T, Matson WR, Beal MF, Myers RH, Bird ED, Milbury P, Saso S (1992) Kynurenine pathway abnormalities in Parkinson's disease. Neurology 42:1702-1706
-
(1992)
Neurology
, vol.42
, pp. 1702-1706
-
-
Ogawa, T.1
Matson, W.R.2
Beal, M.F.3
Myers, R.H.4
Bird, E.D.5
Milbury, P.6
Saso, S.7
-
68
-
-
69249219375
-
Implication of NMDA receptors in the antidyskinetic activity of cabergoline, CI-1041, and Ro 61-8048 in MPTP monkeys with levodopa-induced dyskinesias
-
1:CAS:528:DC%2BD1MXms1agtLs%3D 18704766 10.1007/s12031-008-9137-8
-
Ouattara B, Belkhir S, Morissette M, Dridi M, Samadi P, Gregoire L, Meltzer LT, Di Paolo T (2009) Implication of NMDA receptors in the antidyskinetic activity of cabergoline, CI-1041, and Ro 61-8048 in MPTP monkeys with levodopa-induced dyskinesias. J Mol Neurosci 38:128-142
-
(2009)
J Mol Neurosci
, vol.38
, pp. 128-142
-
-
Ouattara, B.1
Belkhir, S.2
Morissette, M.3
Dridi, M.4
Samadi, P.5
Gregoire, L.6
Meltzer, L.T.7
Di Paolo, T.8
-
69
-
-
77958523402
-
Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition
-
1:CAS:528:DC%2BC3cXhtlyqtLjF 20962239 10.1523/JNEUROSCI.2149-10.2010
-
Paille V, Picconi B, Bagetta V, Ghiglieri V, Sgobio C, Di Filippo M, Viscomi MT, Giampa C, Fusco FR, Gardoni F, Bernardi G, Greengard P, Di Luca M, Calabresi P (2010) Distinct levels of dopamine denervation differentially alter striatal synaptic plasticity and NMDA receptor subunit composition. J Neurosci 30:14182-14193
-
(2010)
J Neurosci
, vol.30
, pp. 14182-14193
-
-
Paille, V.1
Picconi, B.2
Bagetta, V.3
Ghiglieri, V.4
Sgobio, C.5
Di Filippo, M.6
Viscomi, M.T.7
Giampa, C.8
Fusco, F.R.9
Gardoni, F.10
Bernardi, G.11
Greengard, P.12
Di Luca, M.13
Calabresi, P.14
-
71
-
-
78650820598
-
Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation
-
1:CAS:528:DC%2BC3MXhs1Cmug%3D%3D 21055728 10.1016/j.biopsych.2010.08.031
-
Pascoli V, Besnard A, Herve D, Pages C, Heck N, Girault JA, Caboche J, Vanhoutte P (2011) Cyclic adenosine monophosphate-independent tyrosine phosphorylation of NR2B mediates cocaine-induced extracellular signal-regulated kinase activation. Biol Psychiatry 69:218-227
-
(2011)
Biol Psychiatry
, vol.69
, pp. 218-227
-
-
Pascoli, V.1
Besnard, A.2
Herve, D.3
Pages, C.4
Heck, N.5
Girault, J.A.6
Caboche, J.7
Vanhoutte, P.8
-
72
-
-
84855445081
-
Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour
-
1:CAS:528:DC%2BC3MXhsF2jt7bK 10.1038/nature10709
-
Pascoli V, Turiault M, Luscher C (2012) Reversal of cocaine-evoked synaptic potentiation resets drug-induced adaptive behaviour. Nature 481:71-75
-
(2012)
Nature
, vol.481
, pp. 71-75
-
-
Pascoli, V.1
Turiault, M.2
Luscher, C.3
-
73
-
-
14044253562
-
Prevalence and clinical features of hedonistic homeostatic dysregulation in Parkinson's disease
-
DOI 10.1002/mds.20288
-
Pezzella FR, Colosimo C, Vanacore N, Di Rezze S, Chianese M, Fabbrini G, Meco G (2005) Prevalence and clinical features of hedonistic homeostatic dysregulation in Parkinson's disease. Mov Disord 20:77-81 (Pubitemid 40277510)
-
(2005)
Movement Disorders
, vol.20
, Issue.1
, pp. 77-81
-
-
Pezzella, F.R.1
Colosimo, C.2
Vanacore, N.3
Di Rezze, S.4
Chianese, M.5
Fabbrini, G.6
Meco, G.7
-
74
-
-
0037407907
-
Loss of bidirectional striatal synaptic plasticity in L-DOPA-induced dyskinesia
-
Picconi B, Centonze D, Hakansson K, Bernardi G, Greengard P, Fisone G, Cenci MA, Calabresi P (2003) Loss of bidirectional striatal synaptic plasticity in l-DOPA-induced dyskinesia. Nat Neurosci 6:501-506 (Pubitemid 36514698)
-
(2003)
Nature Neuroscience
, vol.6
, Issue.5
, pp. 501-506
-
-
Picconi, B.1
Centonze, D.2
Hakansson, K.3
Bernardi, G.4
Greengard, P.5
Fisone, G.6
Cenci, M.A.7
Calabresi, P.8
-
75
-
-
2942586826
-
2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism
-
DOI 10.1523/JNEUROSCI.1224-04.2004
-
2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism. J Neurosci 24:5283-5291 (Pubitemid 38747668)
-
(2004)
Journal of Neuroscience
, vol.24
, Issue.23
, pp. 5283-5291
-
-
Picconi, B.1
Gardoni, F.2
Centonze, D.3
Mauceri, D.4
Cenci, M.A.5
Bernardi, G.6
Calabresi, P.7
Di Luca, M.8
-
76
-
-
79551716951
-
Inhibition of phosphodiesterases rescues striatal long-term depression and reduces levodopa-induced dyskinesia
-
21183486 10.1093/brain/awq342
-
Picconi B, Bagetta V, Ghiglieri V, Paille V, Di Filippo M, Pendolino V, Tozzi A, Giampa C, Fusco FR, Sgobio C, Calabresi P (2011) Inhibition of phosphodiesterases rescues striatal long-term depression and reduces levodopa-induced dyskinesia. Brain 134:375-387
-
(2011)
Brain
, vol.134
, pp. 375-387
-
-
Picconi, B.1
Bagetta, V.2
Ghiglieri, V.3
Paille, V.4
Di Filippo, M.5
Pendolino, V.6
Tozzi, A.7
Giampa, C.8
Fusco, F.R.9
Sgobio, C.10
Calabresi, P.11
-
77
-
-
84858121110
-
Synaptic dysfunction in Parkinson's disease
-
1:CAS:528:DC%2BC38XhvVajsrvN 22351072 10.1007/978-3-7091-0932-8-24
-
Picconi B, Piccoli G, Calabresi P (2012) Synaptic dysfunction in Parkinson's disease. Adv Exp Med Biol 970:553-572
-
(2012)
Adv Exp Med Biol
, vol.970
, pp. 553-572
-
-
Picconi, B.1
Piccoli, G.2
Calabresi, P.3
-
78
-
-
79957603259
-
Milestones in Parkinson's disease therapeutics
-
21626552 10.1002/mds.23714
-
Rascol O, Lozano A, Stern M, Poewe W (2011) Milestones in Parkinson's disease therapeutics. Mov Disord 26:1072-1082
-
(2011)
Mov Disord
, vol.26
, pp. 1072-1082
-
-
Rascol, O.1
Lozano, A.2
Stern, M.3
Poewe, W.4
-
79
-
-
18144402868
-
Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum
-
DOI 10.1111/j.1471-4159.2005.03134.x
-
Rassoulpour A, Wu HQ, Ferre S, Schwarcz R (2005) Nanomolar concentrations of kynurenic acid reduce extracellular dopamine levels in the striatum. J Neurochem 93:762-765 (Pubitemid 40617635)
-
(2005)
Journal of Neurochemistry
, vol.93
, Issue.3
, pp. 762-765
-
-
Rassoulpour, A.1
Wu, H.-Q.2
Ferre, S.3
Schwarcz, R.4
-
80
-
-
81255160850
-
Dopamine release in the basal ganglia
-
1:CAS:528:DC%2BC3MXhsV2rsLnM 21939738 10.1016/j.neuroscience.2011.08.066
-
Rice ME, Patel JC, Cragg SJ (2011) Dopamine release in the basal ganglia. Neuroscience 198:112-137
-
(2011)
Neuroscience
, vol.198
, pp. 112-137
-
-
Rice, M.E.1
Patel, J.C.2
Cragg, S.J.3
-
81
-
-
4544347756
-
Chronic L-DOPA treatment increases extracellular glutamate levels and GLT1 expression in the basal ganglia in a rat model of Parkinson's disease
-
DOI 10.1111/j.1460-9568.2004.03591.x
-
Robelet S, Melon C, Guillet B, Salin P, Kerkerian-Le Goff L (2004) Chronic l-DOPA treatment increases extracellular glutamate levels and GLT1 expression in the basal ganglia in a rat model of Parkinson's disease. Eur J Neurosci 20:1255-1266 (Pubitemid 39233578)
-
(2004)
European Journal of Neuroscience
, vol.20
, Issue.5
, pp. 1255-1266
-
-
Robelet, S.1
Melon, C.2
Guillet, B.3
Salin, P.4
Kerkerian-Le Goff, L.5
-
82
-
-
0024595656
-
Dyskinesia in the primate following injection of an excitatory amino acid antagonist into the medial segment of the globus pallidus
-
DOI 10.1016/0006-8993(89)91252-3
-
Robertson RG, Farmery SM, Sambrook MA, Crossman AR (1989) Dyskinesia in the primate following injection of an excitatory amino acid antagonist into the medial segment of the globus pallidus. Brain Res 476:317-322 (Pubitemid 19012600)
-
(1989)
Brain Research
, vol.476
, Issue.2
, pp. 317-322
-
-
Robertson, R.G.1
Farmery, S.M.2
Sambrook, M.A.3
Crossman, A.R.4
-
83
-
-
0031696407
-
Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: A target for neuroprotection
-
1:CAS:528:DyaK1cXmtFGktLY%3D 9749591
-
Rodriguez MC, Obeso JA, Olanow CW (1998) Subthalamic nucleus-mediated excitotoxicity in Parkinson's disease: a target for neuroprotection. Ann Neurol 44:S175-S188
-
(1998)
Ann Neurol
, vol.44
-
-
Rodriguez, M.C.1
Obeso, J.A.2
Olanow, C.W.3
-
84
-
-
72149101615
-
Initial clinical manifestations of Parkinson's disease: Features and pathophysiological mechanisms
-
1:CAS:528:DC%2BD1MXhsFymsb%2FF 19909911 10.1016/S1474-4422(09)70293-5
-
Rodriguez-Oroz MC, Jahanshahi M, Krack P, Litvan I, Macias R, Bezard E, Obeso JA (2009) Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms. Lancet Neurol 8:1128-1139
-
(2009)
Lancet Neurol
, vol.8
, pp. 1128-1139
-
-
Rodriguez-Oroz, M.C.1
Jahanshahi, M.2
Krack, P.3
Litvan, I.4
Macias, R.5
Bezard, E.6
Obeso, J.A.7
-
85
-
-
0031434549
-
Synthesis and biochemical evaluation of N-(4-phenylthiazol-2- yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3- hydroxylase
-
DOI 10.1021/jm970467t
-
Rover S, Cesura AM, Huguenin P, Kettler R, Szente A (1997) Synthesis and biochemical evaluation of N-(4-phenylthiazol-2-yl)benzenesulfonamides as high-affinity inhibitors of kynurenine 3-hydroxylase. J Med Chem 40:4378-4385 (Pubitemid 28042317)
-
(1997)
Journal of Medicinal Chemistry
, vol.40
, Issue.26
, pp. 4378-4385
-
-
Rover, S.1
Cesura, A.M.2
Huguenin, P.3
Kettler, R.4
Szente, A.5
-
86
-
-
0742323784
-
The kynurenine pathway of tryptophan degradation as a drug target
-
DOI 10.1016/j.coph.2003.10.006, PII S1471489203002029
-
Schwarcz R (2004) The kynurenine pathway of tryptophan degradation as a drug target. Curr Opin Pharmacol 4:12-17 (Pubitemid 38145832)
-
(2004)
Current Opinion in Pharmacology
, vol.4
, Issue.1
, pp. 12-17
-
-
Schwarcz, R.1
-
87
-
-
0032213310
-
Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation
-
Sgambato V, Pages C, Rogard M, Besson MJ, Caboche J (1998) Extracellular signal-regulated kinase (ERK) controls immediate early gene induction on corticostriatal stimulation. J Neurosci 18:8814-8825 (Pubitemid 28491747)
-
(1998)
Journal of Neuroscience
, vol.18
, Issue.21
, pp. 8814-8825
-
-
Sgambato, V.1
Pages, C.2
Rogard, M.3
Besson, M.-J.4
Caboche, J.5
-
88
-
-
82955189290
-
Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease
-
1:CAS:528:DC%2BC38Xht1ajsL0%3D 22075179 10.1016/j.pneurobio.2011.10.005
-
Sgambato-Faure V, Cenci MA (2012) Glutamatergic mechanisms in the dyskinesias induced by pharmacological dopamine replacement and deep brain stimulation for the treatment of Parkinson's disease. Prog Neurobiol 96:69-86
-
(2012)
Prog Neurobiol
, vol.96
, pp. 69-86
-
-
Sgambato-Faure, V.1
Cenci, M.A.2
-
89
-
-
79953325908
-
Protective effect of l-kynurenine and probenecid on 6-hydroxydopamine- induced striatal toxicity in rats: Implications of modulating kynurenate as a protective strategy
-
1:CAS:528:DC%2BC3MXksFeitbw%3D 20933078 10.1016/j.ntt.2010.10.002
-
Silva-Adaya D, Perez-De La Cruz V, Villeda-Hernandez J, Carrillo-Mora P, Gonzalez-Herrera IG, Garcia E, Colin-Barenque L, Pedraza-Chaverri J, Santamaria A (2011) Protective effect of l-kynurenine and probenecid on 6-hydroxydopamine-induced striatal toxicity in rats: implications of modulating kynurenate as a protective strategy. Neurotoxicol Teratol 33:303-312
-
(2011)
Neurotoxicol Teratol
, vol.33
, pp. 303-312
-
-
Silva-Adaya, D.1
Perez-De La Cruz, V.2
Villeda-Hernandez, J.3
Carrillo-Mora, P.4
Gonzalez-Herrera, I.G.5
Garcia, E.6
Colin-Barenque, L.7
Pedraza-Chaverri, J.8
Santamaria, A.9
-
90
-
-
79955003367
-
The prevalence and clinical characteristics of punding in Parkinson's disease
-
21648123 10.1002/mds.23508
-
Spencer AH, Rickards H, Fasano A, Cavanna AE (2011) The prevalence and clinical characteristics of punding in Parkinson's disease. Mov Disord 26:578-586
-
(2011)
Mov Disord
, vol.26
, pp. 578-586
-
-
Spencer, A.H.1
Rickards, H.2
Fasano, A.3
Cavanna, A.E.4
-
91
-
-
0034176154
-
Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection
-
DOI 10.1016/S0165-6147(00)01451-6, PII S0165614700014516
-
Stone TW (2000) Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection. Trends Pharmacol Sci 21:149-154 (Pubitemid 30190140)
-
(2000)
Trends in Pharmacological Sciences
, vol.21
, Issue.4
, pp. 149-154
-
-
Stone, T.W.1
-
92
-
-
44949176630
-
Dopamine agonist therapy in early Parkinson's disease
-
CD006564
-
Stowe RL, Ives NJ, Clarke C, van Hilten J, Ferreira J, Hawker RJ, Shah L, Wheatley K, Gray R (2008) Dopamine agonist therapy in early Parkinson's disease. Cochrane Database Syst Rev (2):CD006564
-
(2008)
Cochrane Database Syst Rev
, Issue.2
-
-
Stowe, R.L.1
Ives, N.J.2
Clarke, C.3
Van Hilten, J.4
Ferreira, J.5
Hawker, R.J.6
Shah, L.7
Wheatley, K.8
Gray, R.9
-
93
-
-
84860523932
-
Mitochondrial disturbances, tryptophan metabolites and neurodegeneration: Medicinal chemistry aspects
-
1:CAS:528:DC%2BC38XmsF2htb8%3D 22429096 10.2174/092986712800167365
-
Szalardy L, Klivenyi P, Zadori D, Fulop F, Toldi J, Vecsei L (2012) Mitochondrial disturbances, tryptophan metabolites and neurodegeneration: medicinal chemistry aspects. Curr Med Chem 19:1899-1920
-
(2012)
Curr Med Chem
, vol.19
, pp. 1899-1920
-
-
Szalardy, L.1
Klivenyi, P.2
Zadori, D.3
Fulop, F.4
Toldi, J.5
Vecsei, L.6
-
94
-
-
19944428022
-
Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum
-
DOI 10.1073/pnas.0408305102
-
Valjent E, Pascoli V, Svenningsson P, Paul S, Enslen H, Corvol JC, Stipanovich A, Caboche J, Lombroso PJ, Nairn AC, Greengard P, Herve D, Girault JA (2005) Regulation of a protein phosphatase cascade allows convergent dopamine and glutamate signals to activate ERK in the striatum. Proc Natl Acad Sci USA 102:491-496 (Pubitemid 40116794)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.2
, pp. 491-496
-
-
Valjent, E.1
Pascoli, V.2
Svenningsson, P.3
Paul, S.4
Enslen, H.5
Corvol, J.-C.6
Stipanovich, A.7
Caboche, J.8
Lombroso, P.J.9
Nairn, A.C.10
Greengard, P.11
Herve, D.12
Girault, J.-A.13
-
95
-
-
33749823140
-
Prevalence of repetitive and reward-seeking behaviors in Parkinson disease
-
DOI 10.1212/01.wnl.0000238503.20816.13, PII 0000611420061010000030
-
Voon V, Hassan K, Zurowski M, de Souza M, Thomsen T, Fox S, Lang AE, Miyasaki J (2006) Prevalence of repetitive and reward-seeking behaviors in Parkinson disease. Neurology 67:1254-1257 (Pubitemid 44563838)
-
(2006)
Neurology
, vol.67
, Issue.7
, pp. 1254-1257
-
-
Voon, V.1
Hassan, K.2
Zurowski, M.3
De Souza, M.4
Thomsen, T.5
Fox, S.6
Lang, A.E.7
Miyasaki, J.8
-
96
-
-
0036202546
-
Effect of systemic L-DOPA administration on extracellular kynurenate levels in the rat striatum
-
DOI 10.1007/s007020200020
-
Wu HQ, Rassoulpour A, Schwarcz R (2002) Effect of systemic l-DOPA administration on extracellular kynurenate levels in the rat striatum. J Neural Transm 109:239-249 (Pubitemid 34251630)
-
(2002)
Journal of Neural Transmission
, vol.109
, Issue.3
, pp. 239-249
-
-
Wu, H.-Q.1
Rassoulpour, A.2
Schwarcz, R.3
-
97
-
-
85099491079
-
DARPP-32, Jack of all trades. master of which?
-
1:CAS:528:DC%2BC3MXhs1KhsbjO 21927600 10.3389/fnbeh.2011.00056
-
Yger M, Girault JA (2011) DARPP-32, Jack of all trades. master of which? Front Behav Neurosci 5:56
-
(2011)
Front Behav Neurosci
, vol.5
, pp. 56
-
-
Yger, M.1
Girault, J.A.2
-
98
-
-
79953225482
-
Time-course of kynurenic acid concentration in mouse serum following the administration of a novel kynurenic acid analog
-
1:CAS:528:DC%2BC3MXkt12gu7o%3D 21392919 10.1016/j.jpba.2011.02.014
-
Zadori D, Ilisz I, Klivenyi P, Szatmari I, Fulop F, Toldi J, Vecsei L, Peter A (2011a) Time-course of kynurenic acid concentration in mouse serum following the administration of a novel kynurenic acid analog. J Pharm Biomed Anal 55:540-543
-
(2011)
J Pharm Biomed Anal
, vol.55
, pp. 540-543
-
-
Zadori, D.1
Ilisz, I.2
Klivenyi, P.3
Szatmari, I.4
Fulop, F.5
Toldi, J.6
Vecsei, L.7
Peter, A.8
-
99
-
-
79955675748
-
Endogenous neuroprotection in chronic neurodegenerative disorders: With particular regard to the kynurenines
-
1:CAS:528:DC%2BC3MXmslWlsro%3D 21155972 10.1111/j.1582-4934.2010.01237.x
-
Zadori D, Klivenyi P, Plangar I, Toldi J, Vecsei L (2011b) Endogenous neuroprotection in chronic neurodegenerative disorders: with particular regard to the kynurenines. J Cell Mol Med 15:701-717
-
(2011)
J Cell Mol Med
, vol.15
, pp. 701-717
-
-
Zadori, D.1
Klivenyi, P.2
Plangar, I.3
Toldi, J.4
Vecsei, L.5
-
100
-
-
79955661135
-
Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease
-
1:CAS:528:DC%2BC3MXmvVehur0%3D 21194001 10.1007/s00702-010-0573-6
-
Zadori D, Nyiri G, Szonyi A, Szatmari I, Fulop F, Toldi J, Freund TF, Vecsei L, Klivenyi P (2011c) Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease. J Neural Transm 118:865-875
-
(2011)
J Neural Transm
, vol.118
, pp. 865-875
-
-
Zadori, D.1
Nyiri, G.2
Szonyi, A.3
Szatmari, I.4
Fulop, F.5
Toldi, J.6
Freund, T.F.7
Vecsei, L.8
Klivenyi, P.9
-
101
-
-
84857624732
-
Kynurenines in Parkinson's disease: Therapeutic perspectives
-
1:CAS:528:DC%2BC38XhsVOltrY%3D 21858430 10.1007/s00702-011-0697-3
-
Zadori D, Klivenyi P, Toldi J, Fulop F, Vecsei L (2012) Kynurenines in Parkinson's disease: therapeutic perspectives. J Neural Transm 119:275-283
-
(2012)
J Neural Transm
, vol.119
, pp. 275-283
-
-
Zadori, D.1
Klivenyi, P.2
Toldi, J.3
Fulop, F.4
Vecsei, L.5
-
102
-
-
79958021894
-
Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration
-
1:CAS:528:DC%2BC3MXnsVOkt74%3D 21640374 10.1016/j.cell.2011.05.020
-
Zwilling D, Huang SY, Sathyasaikumar KV, Notarangelo FM, Guidetti P, Wu HQ, Lee J, Truong J, Andrews-Zwilling Y, Hsieh EW, Louie JY, Wu T, Scearce-Levie K, Patrick C, Adame A, Giorgini F, Moussaoui S, Laue G, Rassoulpour A, Flik G, Huang Y, Muchowski JM, Masliah E, Schwarcz R, Muchowski PJ (2011) Kynurenine 3-monooxygenase inhibition in blood ameliorates neurodegeneration. Cell 145:863-874
-
(2011)
Cell
, vol.145
, pp. 863-874
-
-
Zwilling, D.1
Huang, S.Y.2
Sathyasaikumar, K.V.3
Notarangelo, F.M.4
Guidetti, P.5
Wu, H.Q.6
Lee, J.7
Truong, J.8
Andrews-Zwilling, Y.9
Hsieh, E.W.10
Louie, J.Y.11
Wu, T.12
Scearce-Levie, K.13
Patrick, C.14
Adame, A.15
Giorgini, F.16
Moussaoui, S.17
Laue, G.18
Rassoulpour, A.19
Flik, G.20
Huang, Y.21
Muchowski, J.M.22
Masliah, E.23
Schwarcz, R.24
Muchowski, P.J.25
more..
|