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Volumn 85, Issue 3-4, 2011, Pages 133-140

Protective effects of synthetic kynurenines on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

Author keywords

Inflammation; Mice; MPTP; Oxidative stress; Substantia nigra

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; INDUCIBLE NITRIC OXIDE SYNTHASE; KYNURENINE; NITRIC OXIDE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE);

EID: 79957802304     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2011.03.008     Document Type: Article
Times cited : (17)

References (51)
  • 1
    • 27644507326 scopus 로고    scopus 로고
    • Melatonin and nitric oxide: two required antagonists for mitochondrial homeostasis
    • Acuña-Castroviejo D., Escames G., López L.C., Hitos A.B., León J. Melatonin and nitric oxide: two required antagonists for mitochondrial homeostasis. Endocrine 2005, 27:159-168.
    • (2005) Endocrine , vol.27 , pp. 159-168
    • Acuña-Castroviejo, D.1    Escames, G.2    López, L.C.3    Hitos, A.B.4    León, J.5
  • 2
    • 0030582674 scopus 로고    scopus 로고
    • Nitric oxide acts directly in the presynaptic neuron to produce long term potentiation in cultured hippocampal neurons
    • Arancio O., Kiebler M., Lee C.J., Lev-Ram V., Tsien R.Y., Kandel E.R., Hawkins R.D. Nitric oxide acts directly in the presynaptic neuron to produce long term potentiation in cultured hippocampal neurons. Cell 1996, 87:1025-1035.
    • (1996) Cell , vol.87 , pp. 1025-1035
    • Arancio, O.1    Kiebler, M.2    Lee, C.J.3    Lev-Ram, V.4    Tsien, R.Y.5    Kandel, E.R.6    Hawkins, R.D.7
  • 3
    • 0036024973 scopus 로고    scopus 로고
    • In vivo and in organello assessment of OXPHOS activities
    • Barrientos A. In vivo and in organello assessment of OXPHOS activities. Methods 2002, 26:307-316.
    • (2002) Methods , vol.26 , pp. 307-316
    • Barrientos, A.1
  • 4
    • 77957664714 scopus 로고    scopus 로고
    • An update on the potential role of excitotoxicity in the pathogenesis of Parkinson's disease
    • Blandini.F F. An update on the potential role of excitotoxicity in the pathogenesis of Parkinson's disease. Func. Neurol. 2010, 25:65-71.
    • (2010) Func. Neurol. , vol.25 , pp. 65-71
    • Blandini.F, F.1
  • 5
    • 0032740245 scopus 로고    scopus 로고
    • Endogenous nitric oxide synthesis: biological functions and pathophysiology
    • Bredt D.S. Endogenous nitric oxide synthesis: biological functions and pathophysiology. Free. Radic. Res. 1999, 31:577-596.
    • (1999) Free. Radic. Res. , vol.31 , pp. 577-596
    • Bredt, D.S.1
  • 6
    • 0024378999 scopus 로고
    • Nitric oxide mediates glutamate linked enhancement of cGMP levels in the cerebellum
    • Bredt D.S., Snyder S.H. Nitric oxide mediates glutamate linked enhancement of cGMP levels in the cerebellum. Proc. Natl. Acad. Sci. U. S. A. 1989, 86:9030-9033.
    • (1989) Proc. Natl. Acad. Sci. U. S. A. , vol.86 , pp. 9030-9033
    • Bredt, D.S.1    Snyder, S.H.2
  • 7
    • 0035282782 scopus 로고    scopus 로고
    • Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase
    • Brown G.C. Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome c oxidase. Biochim. Biophys. Acta 2001, 1504:46-57.
    • (2001) Biochim. Biophys. Acta , vol.1504 , pp. 46-57
    • Brown, G.C.1
  • 8
    • 77956012154 scopus 로고    scopus 로고
    • Nitric oxide and neuronal death
    • Brown G.C. Nitric oxide and neuronal death. Nitric Oxide 2010, 23:153-165.
    • (2010) Nitric Oxide , vol.23 , pp. 153-165
    • Brown, G.C.1
  • 9
    • 3543008400 scopus 로고    scopus 로고
    • Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols
    • Brown G.C., Boroutaite V. Inhibition of mitochondrial respiratory complex I by nitric oxide, peroxynitrite and S-nitrosothiols. Biochim. Biophys. Acta 2004, 1658:44-49.
    • (2004) Biochim. Biophys. Acta , vol.1658 , pp. 44-49
    • Brown, G.C.1    Boroutaite, V.2
  • 11
    • 0141741347 scopus 로고    scopus 로고
    • Parkinson's disease: mechanisms and models
    • Dauer W., Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003, 39:889-909.
    • (2003) Neuron , vol.39 , pp. 889-909
    • Dauer, W.1    Przedborski, S.2
  • 12
    • 0038661151 scopus 로고    scopus 로고
    • Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats
    • Escames G., Leon J., Macias M., Khaldy H., Acuña-Castroviejo D. Melatonin counteracts lipopolysaccharide-induced expression and activity of mitochondrial nitric oxide synthase in rats. FASEB J. 2003, 17:932-934.
    • (2003) FASEB J. , vol.17 , pp. 932-934
    • Escames, G.1    Leon, J.2    Macias, M.3    Khaldy, H.4    Acuña-Castroviejo, D.5
  • 13
    • 0025127633 scopus 로고
    • Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal
    • Esterbauer H., Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 1990, 186:407-421.
    • (1990) Methods Enzymol. , vol.186 , pp. 407-421
    • Esterbauer, H.1    Cheeseman, K.H.2
  • 14
    • 77952889195 scopus 로고    scopus 로고
    • The multiple actions of NO
    • Gao Y. The multiple actions of NO. Pflugers Arch. 2010, 459:829-839.
    • (2010) Pflugers Arch. , vol.459 , pp. 829-839
    • Gao, Y.1
  • 16
    • 0013939811 scopus 로고
    • Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain
    • Glowinski J., Iversen L.L. Regional studies of catecholamines in the rat brain. I. The disposition of [3H]norepinephrine, [3H]dopamine and [3H]dopa in various regions of the brain. J. Neurochem. 1966, 13:655-669.
    • (1966) J. Neurochem. , vol.13 , pp. 655-669
    • Glowinski, J.1    Iversen, L.L.2
  • 18
    • 2542431131 scopus 로고    scopus 로고
    • Rationale for and use of NMDA receptor antagonists in Parkinson's disease
    • Hallett P.J., Standaert D.J. Rationale for and use of NMDA receptor antagonists in Parkinson's disease. Pharmacol. Ther. 2004, 102:155-174.
    • (2004) Pharmacol. Ther. , vol.102 , pp. 155-174
    • Hallett, P.J.1    Standaert, D.J.2
  • 19
    • 2142694340 scopus 로고    scopus 로고
    • Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signalling
    • Hong S.J., Dawson T.M., Dawson V.L. Nuclear and mitochondrial conversations in cell death: PARP-1 and AIF signalling. Trends Pharmacol. Sci. 2004, 25:259-264.
    • (2004) Trends Pharmacol. Sci. , vol.25 , pp. 259-264
    • Hong, S.J.1    Dawson, T.M.2    Dawson, V.L.3
  • 20
    • 0037378026 scopus 로고    scopus 로고
    • Oxidative stress in Parkinson's disease
    • Jenner P. Oxidative stress in Parkinson's disease. Ann. Neurol. 2003, 53:S26-S36.
    • (2003) Ann. Neurol. , vol.53
    • Jenner, P.1
  • 22
    • 0037405378 scopus 로고    scopus 로고
    • Synergistic effects of melatonin and deprenyl protect against MPTP-induced mitochondrial damage and DA depletion
    • Khaldy H., León J., Escames G., Bikjdaouene L., Acuña-Castroviejo D. Synergistic effects of melatonin and deprenyl protect against MPTP-induced mitochondrial damage and DA depletion. Neurobiol. Aging 2003, 24:491-500.
    • (2003) Neurobiol. Aging , vol.24 , pp. 491-500
    • Khaldy, H.1    León, J.2    Escames, G.3    Bikjdaouene, L.4    Acuña-Castroviejo, D.5
  • 25
    • 0345451050 scopus 로고    scopus 로고
    • Modulation of rat striatal glutamatergic response in search for new neuroprotective agents: evaluation of melatonin and some kynurenine derivatives
    • León J., Vives F., Gómez I., Camacho E., Gallo M.A., Espinosa A., Escames G., Acuña-Castroviejo D. Modulation of rat striatal glutamatergic response in search for new neuroprotective agents: evaluation of melatonin and some kynurenine derivatives. Brain Res. Bull. 1998, 45:525-530.
    • (1998) Brain Res. Bull. , vol.45 , pp. 525-530
    • León, J.1    Vives, F.2    Gómez, I.3    Camacho, E.4    Gallo, M.A.5    Espinosa, A.6    Escames, G.7    Acuña-Castroviejo, D.8
  • 26
    • 0034728096 scopus 로고    scopus 로고
    • Mitochondrial respiratory chain disorders II: neurodegenerative disorders and nuclear gene defects
    • Leonard J.V., Schapira A.H. Mitochondrial respiratory chain disorders II: neurodegenerative disorders and nuclear gene defects. Lancet 2000, 355:389-394.
    • (2000) Lancet , vol.355 , pp. 389-394
    • Leonard, J.V.1    Schapira, A.H.2
  • 29
    • 27744498588 scopus 로고    scopus 로고
    • Identification of an inducible nitric oxide synthase in diaphragm mitochondria from septic mice: its relation with mitochondrial dysfunction and prevention by melatonin
    • López L.C., Escames G., Tapias V., Utrilla P., Leon J., Acuna-Castroviejo D. Identification of an inducible nitric oxide synthase in diaphragm mitochondria from septic mice: its relation with mitochondrial dysfunction and prevention by melatonin. Int. J. Biochem. Cell Biol. 2006, 38:267-278.
    • (2006) Int. J. Biochem. Cell Biol. , vol.38 , pp. 267-278
    • López, L.C.1    Escames, G.2    Tapias, V.3    Utrilla, P.4    Leon, J.5    Acuna-Castroviejo, D.6
  • 30
    • 59149094114 scopus 로고    scopus 로고
    • Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production
    • López A., García J.A., Escames G., Venegas C., Ortiz F., López L.C., Acuña-Castroviejo D. Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J. Pineal Res. 2009, 46:188-198.
    • (2009) J. Pineal Res. , vol.46 , pp. 188-198
    • López, A.1    García, J.A.2    Escames, G.3    Venegas, C.4    Ortiz, F.5    López, L.C.6    Acuña-Castroviejo, D.7
  • 32
    • 0028026868 scopus 로고
    • Nitric oxide synthase: aspects concerning structure and catalysis
    • Marletta M.A. Nitric oxide synthase: aspects concerning structure and catalysis. Cell 1994, 78:927-930.
    • (1994) Cell , vol.78 , pp. 927-930
    • Marletta, M.A.1
  • 33
    • 0033822805 scopus 로고    scopus 로고
    • Melatonin but not vitamins C and E maintains glutathione homeostasis in t-butyl hydroperoxide-induced mitochondrial oxidative stress
    • Martín M., Macías M., Escames G., León J., Acuña-Castroviejo D. Melatonin but not vitamins C and E maintains glutathione homeostasis in t-butyl hydroperoxide-induced mitochondrial oxidative stress. FASEB J. 2000, 14:1677-1679.
    • (2000) FASEB J. , vol.14 , pp. 1677-1679
    • Martín, M.1    Macías, M.2    Escames, G.3    León, J.4    Acuña-Castroviejo, D.5
  • 34
    • 0026587806 scopus 로고
    • Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
    • Moratalla R., Quinn B., DeLanney L.E., Irwin I., Langston J.W., Graybiel A.M. Differential vulnerability of primate caudate-putamen and striosome-matrix dopamine systems to the neurotoxic effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. Proc. Natl. Acad. Sci. U. S. A. 1992, 89:3859-3863.
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 3859-3863
    • Moratalla, R.1    Quinn, B.2    DeLanney, L.E.3    Irwin, I.4    Langston, J.W.5    Graybiel, A.M.6
  • 35
    • 79952103900 scopus 로고    scopus 로고
    • S-Nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases
    • doi:10.1089/ars.2010
    • Nakamura T., Lipton S.A. S-Nitrosylation of critical protein thiols mediates protein misfolding and mitochondrial dysfunction in neurodegenerative diseases. Antioxid. Redox Signal. 2010, 3570. doi:10.1089/ars.2010.
    • (2010) Antioxid. Redox Signal. , pp. 3570
    • Nakamura, T.1    Lipton, S.A.2
  • 36
    • 78649982888 scopus 로고    scopus 로고
    • Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity
    • Navarro A., Bández M.J., Gómez C., Repetto M.G., Boveris A. Effects of rotenone and pyridaben on complex I electron transfer and on mitochondrial nitric oxide synthase functional activity. J. Bioenerg. Biomembr. 2010, 10.1007/s10863-010-9309-4.
    • (2010) J. Bioenerg. Biomembr.
    • Navarro, A.1    Bández, M.J.2    Gómez, C.3    Repetto, M.G.4    Boveris, A.5
  • 37
    • 76949089544 scopus 로고    scopus 로고
    • Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease
    • Navarro A., Boveris A. Brain mitochondrial dysfunction and oxidative damage in Parkinson's disease. J. Bioenerg. Biomembr. 2009, 41:517-521.
    • (2009) J. Bioenerg. Biomembr. , vol.41 , pp. 517-521
    • Navarro, A.1    Boveris, A.2
  • 38
    • 77957943337 scopus 로고    scopus 로고
    • The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6
    • Niranjan R., Nath C., Shukla R. The mechanism of action of MPTP-induced neuroinflammation and its modulation by melatonin in rat astrocytoma cells, C6. Free Radic. Res. 2010, 44:1304-1316.
    • (2010) Free Radic. Res. , vol.44 , pp. 1304-1316
    • Niranjan, R.1    Nath, C.2    Shukla, R.3
  • 40
    • 0036386814 scopus 로고    scopus 로고
    • Glutamate-mediated striatal dysregulation and the pathogenesis of motor response complications in Parkinson's disease
    • Oh J.D., Chase T.N. Glutamate-mediated striatal dysregulation and the pathogenesis of motor response complications in Parkinson's disease. Amino Acids 2002, 23:133-139.
    • (2002) Amino Acids , vol.23 , pp. 133-139
    • Oh, J.D.1    Chase, T.N.2
  • 41
    • 38649105151 scopus 로고    scopus 로고
    • Inactivation of mitochondrial respiratory chain complex I leads mitochondrial nitric oxide synthase to become pro-oxidative
    • Parihar M.S., Parihar A., Villamena F.A., Vaccaro P.S., Ghafourifar P. Inactivation of mitochondrial respiratory chain complex I leads mitochondrial nitric oxide synthase to become pro-oxidative. Biochem. Biophys. Res. Commun. 2008, 367:761-767.
    • (2008) Biochem. Biophys. Res. Commun. , vol.367 , pp. 761-767
    • Parihar, M.S.1    Parihar, A.2    Villamena, F.A.3    Vaccaro, P.S.4    Ghafourifar, P.5
  • 42
    • 10244222286 scopus 로고    scopus 로고
    • MPTP as a mitochondrial neurotoxin model of Parkinson's disease
    • Przedborski S., Tieu K., Perier C., Vila M. MPTP as a mitochondrial neurotoxin model of Parkinson's disease. J. Bioenerg. Biomembr. 2004, 36:375-379.
    • (2004) J. Bioenerg. Biomembr. , vol.36 , pp. 375-379
    • Przedborski, S.1    Tieu, K.2    Perier, C.3    Vila, M.4
  • 43
    • 34249085665 scopus 로고    scopus 로고
    • NMDA and AMPA receptors: old channels, new tricks
    • Rao V.R., Finkbeiner S. NMDA and AMPA receptors: old channels, new tricks. Trends Neurosci. 2007, 30:284-291.
    • (2007) Trends Neurosci. , vol.30 , pp. 284-291
    • Rao, V.R.1    Finkbeiner, S.2
  • 44
    • 0141705360 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases
    • Rego A.C., Oliveira C.R. Mitochondrial dysfunction and reactive oxygen species in excitotoxicity and apoptosis: implications for the pathogenesis of neurodegenerative diseases. Neurochem. Res. 2003, 28:1563-1574.
    • (2003) Neurochem. Res. , vol.28 , pp. 1563-1574
    • Rego, A.C.1    Oliveira, C.R.2
  • 45
    • 0035477926 scopus 로고    scopus 로고
    • Nitric oxide inhibits mitochondrial NADH: ubiquinone reductase activity through peroxynitrite formation
    • Riobo N.A., Clementi E., Melani M., Boveris A., Cadenas E., Moncada S., Poderoso J.J. Nitric oxide inhibits mitochondrial NADH: ubiquinone reductase activity through peroxynitrite formation. Biochem. J. 2001, 359:139-145.
    • (2001) Biochem. J. , vol.359 , pp. 139-145
    • Riobo, N.A.1    Clementi, E.2    Melani, M.3    Boveris, A.4    Cadenas, E.5    Moncada, S.6    Poderoso, J.J.7
  • 46
    • 77954657877 scopus 로고    scopus 로고
    • Complex I: inhibitors, inhibition and neurodegeneration
    • Schapira A.H. Complex I: inhibitors, inhibition and neurodegeneration. Exp. Neurol. 2010, 224:331-335.
    • (2010) Exp. Neurol. , vol.224 , pp. 331-335
    • Schapira, A.H.1
  • 47
    • 0036716889 scopus 로고    scopus 로고
    • MPTP: insights into parkinsonian neurodegeneration
    • Speciale S.G. MPTP: insights into parkinsonian neurodegeneration. Neurotoxicol. Teratol. 2002, 24:607-620.
    • (2002) Neurotoxicol. Teratol. , vol.24 , pp. 607-620
    • Speciale, S.G.1
  • 50
    • 3542996356 scopus 로고    scopus 로고
    • Role of calcium signaling in the activation of mitochondrial nitric oxide synthase and citric acid cycle
    • Traaseth N., Elfering S., Solien J., Haynes V., Giulivi C. Role of calcium signaling in the activation of mitochondrial nitric oxide synthase and citric acid cycle. Biochim. Biophys. Acta 2004, 1658:64-71.
    • (2004) Biochim. Biophys. Acta , vol.1658 , pp. 64-71
    • Traaseth, N.1    Elfering, S.2    Solien, J.3    Haynes, V.4    Giulivi, C.5
  • 51
    • 0142150051 scopus 로고    scopus 로고
    • Mitochondrial formation of reactive oxygen species
    • Turrens J.F. Mitochondrial formation of reactive oxygen species. J. Physiol. 2003, 552:335-344.
    • (2003) J. Physiol. , vol.552 , pp. 335-344
    • Turrens, J.F.1


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