-
1
-
-
33947308625
-
-
Nova Science Publishers, Inc., New York, L. Vecsei (Ed.)
-
Kynurenines in the Brain 2005, Nova Science Publishers, Inc., New York. L. Vecsei (Ed.).
-
(2005)
Kynurenines in the Brain
-
-
-
2
-
-
22144432194
-
Role of kynurenines in the central and peripheral nervous systems
-
Nemeth H., Toldi J., Vecsei L. Role of kynurenines in the central and peripheral nervous systems. Curr. Neurovasc. Res. 2005, 2:249-260.
-
(2005)
Curr. Neurovasc. Res.
, vol.2
, pp. 249-260
-
-
Nemeth, H.1
Toldi, J.2
Vecsei, L.3
-
3
-
-
70449523216
-
Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies
-
Zadori D., Klivenyi P., Vamos E., Fulop F., Toldi J., Vecsei L. Kynurenines in chronic neurodegenerative disorders: future therapeutic strategies. J. Neural Transm. 2009, 116:1403-1409.
-
(2009)
J. Neural Transm.
, vol.116
, pp. 1403-1409
-
-
Zadori, D.1
Klivenyi, P.2
Vamos, E.3
Fulop, F.4
Toldi, J.5
Vecsei, L.6
-
4
-
-
0036690151
-
Endogenous kynurenines as targets for drug discovery and development
-
Stone T.W., Darlington L.G. Endogenous kynurenines as targets for drug discovery and development. Nat. Rev. Drug. Discov. 2002, 1:609-620.
-
(2002)
Nat. Rev. Drug. Discov.
, vol.1
, pp. 609-620
-
-
Stone, T.W.1
Darlington, L.G.2
-
5
-
-
0026076136
-
Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism
-
Fukui S., Schwarcz R., Rapoport S.I., Takada Y., Smith Q.R. Blood-brain barrier transport of kynurenines: implications for brain synthesis and metabolism. J. Neurochem. 1991, 56:2007-2017.
-
(1991)
J. Neurochem.
, vol.56
, pp. 2007-2017
-
-
Fukui, S.1
Schwarcz, R.2
Rapoport, S.I.3
Takada, Y.4
Smith, Q.R.5
-
6
-
-
26844476662
-
Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites
-
Bahn A., Ljubojevic M., Lorenz H., Schultz C., Ghebremedhin E., Ugele B., Sabolic I., Burckhardt G., Hagos Y. Murine renal organic anion transporters mOAT1 and mOAT3 facilitate the transport of neuroactive tryptophan metabolites. Am. J. Physiol. Cell. Physiol. 2005, 289:C1075-1084.
-
(2005)
Am. J. Physiol. Cell. Physiol.
, vol.289
-
-
Bahn, A.1
Ljubojevic, M.2
Lorenz, H.3
Schultz, C.4
Ghebremedhin, E.5
Ugele, B.6
Sabolic, I.7
Burckhardt, G.8
Hagos, Y.9
-
7
-
-
0742323784
-
The kynurenine pathway of tryptophan degradation as a drug target
-
Schwarcz R. The kynurenine pathway of tryptophan degradation as a drug target. Curr. Opin. Pharmacol. 2004, 4:12-17.
-
(2004)
Curr. Opin. Pharmacol.
, vol.4
, pp. 12-17
-
-
Schwarcz, R.1
-
8
-
-
0034176154
-
Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection
-
Stone T.W. Development and therapeutic potential of kynurenic acid and kynurenine derivatives for neuroprotection. Trends Pharmacol. Sci. 2000, 21:149-154.
-
(2000)
Trends Pharmacol. Sci.
, vol.21
, pp. 149-154
-
-
Stone, T.W.1
-
9
-
-
71949108894
-
Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives
-
Fulop F., Szatmari I., Vamos E., Zadori D., Toldi J., Vecsei L. Syntheses, transformations and pharmaceutical applications of kynurenic acid derivatives. Curr. Med. Chem. 2009, 16:4828-4842.
-
(2009)
Curr. Med. Chem.
, vol.16
, pp. 4828-4842
-
-
Fulop, F.1
Szatmari, I.2
Vamos, E.3
Zadori, D.4
Toldi, J.5
Vecsei, L.6
-
10
-
-
77249133018
-
A novel kynurenic acid analogue: a comparison with kynurenic acid. An in vitro electrophysiological study
-
Marosi M., Nagy D., Farkas T., Kis Z., Rozsa E., Robotka H., Fulop F., Vecsei L., Toldi J. A novel kynurenic acid analogue: a comparison with kynurenic acid. An in vitro electrophysiological study. J. Neural Transm. 2010, 117:183-188.
-
(2010)
J. Neural Transm.
, vol.117
, pp. 183-188
-
-
Marosi, M.1
Nagy, D.2
Farkas, T.3
Kis, Z.4
Rozsa, E.5
Robotka, H.6
Fulop, F.7
Vecsei, L.8
Toldi, J.9
-
11
-
-
68749117393
-
L-Kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus
-
Vamos E., Pardutz A., Varga H., Bohar Z., Tajti J., Fulop F., Toldi J., Vecsei L. l-Kynurenine combined with probenecid and the novel synthetic kynurenic acid derivative attenuate nitroglycerin-induced nNOS in the rat caudal trigeminal nucleus. Neuropharmacology 2009, 57:425-429.
-
(2009)
Neuropharmacology
, vol.57
, pp. 425-429
-
-
Vamos, E.1
Pardutz, A.2
Varga, H.3
Bohar, Z.4
Tajti, J.5
Fulop, F.6
Toldi, J.7
Vecsei, L.8
-
12
-
-
77951836040
-
Kynurenate derivative attenuates the nitroglycerin-induced CamKIIalpha and CGRP expression changes
-
Vamos E., Fejes A., Koch J., Tajti J., Fulop F., Toldi J., Pardutz A., Vecsei L. Kynurenate derivative attenuates the nitroglycerin-induced CamKIIalpha and CGRP expression changes. Headache 2010, 50:834-843.
-
(2010)
Headache
, vol.50
, pp. 834-843
-
-
Vamos, E.1
Fejes, A.2
Koch, J.3
Tajti, J.4
Fulop, F.5
Toldi, J.6
Pardutz, A.7
Vecsei, L.8
-
13
-
-
79955661135
-
-
Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease, J. Neural Transm., doi:10.1007/s00702-010-0573-6.
-
D. Zadori, G. Nyiri, A. Szonyi, I. Szatmari, F. Fulop, J. Toldi, T.F. Freund, L. Vecsei, P. Klivenyi, Neuroprotective effects of a novel kynurenic acid analogue in a transgenic mouse model of Huntington's disease, J. Neural Transm., doi:10.1007/s00702-010-0573-6.
-
-
-
Zadori, D.1
Nyiri, G.2
Szonyi, A.3
Szatmari, I.4
Fulop, F.5
Toldi, J.6
Freund, T.F.7
Vecsei, L.8
Klivenyi, P.9
-
14
-
-
65549110631
-
Simultaneous determination of tryptophan and kynurenine in plasma samples of children patients with Kawasaki disease by high-performance liquid chromatography with programmed wavelength ultraviolet detection
-
Zhang X., He Y., Ding M. Simultaneous determination of tryptophan and kynurenine in plasma samples of children patients with Kawasaki disease by high-performance liquid chromatography with programmed wavelength ultraviolet detection. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2009, 877:1678-1682.
-
(2009)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.877
, pp. 1678-1682
-
-
Zhang, X.1
He, Y.2
Ding, M.3
-
15
-
-
67349091402
-
Analysis of tryptophan catabolism in HBV patients by HPLC with programmed wavelength ultraviolet detection
-
Ma L., Xu B., Wang W., Deng W., Ding M. Analysis of tryptophan catabolism in HBV patients by HPLC with programmed wavelength ultraviolet detection. Clin. Chim. Acta 2009, 405:94-96.
-
(2009)
Clin. Chim. Acta
, vol.405
, pp. 94-96
-
-
Ma, L.1
Xu, B.2
Wang, W.3
Deng, W.4
Ding, M.5
-
16
-
-
0028784927
-
Systemic administration of kainate induces marked increases of endogenous kynurenic acid in various brain regions and plasma of rats
-
Baran H., Gramer M., Honack D., Loscher W. Systemic administration of kainate induces marked increases of endogenous kynurenic acid in various brain regions and plasma of rats. Eur. J. Pharmacol. 1995, 286:167-175.
-
(1995)
Eur. J. Pharmacol.
, vol.286
, pp. 167-175
-
-
Baran, H.1
Gramer, M.2
Honack, D.3
Loscher, W.4
-
17
-
-
33644753798
-
Improved method for the determination of kynurenic acid in rat plasma by column-switching HPLC with post-column fluorescence detection
-
Mitsuhashi S., Fukushima T., Kawai J., Tomiya M., Santa T., Imai K., Toyo'oka T. Improved method for the determination of kynurenic acid in rat plasma by column-switching HPLC with post-column fluorescence detection. Anal. Chim. Acta 2006, 562:36-43.
-
(2006)
Anal. Chim. Acta
, vol.562
, pp. 36-43
-
-
Mitsuhashi, S.1
Fukushima, T.2
Kawai, J.3
Tomiya, M.4
Santa, T.5
Imai, K.6
Toyo'oka, T.7
-
18
-
-
33847262628
-
Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma
-
Mitsuhashi S., Fukushima T., Arai K., Tomiya M., Santa T., Imai K., Toyo'oka T. Development of a column-switching high-performance liquid chromatography for kynurenine enantiomers and its application to a pharmacokinetic study in rat plasma. Anal. Chim. Acta 2007, 587:60-66.
-
(2007)
Anal. Chim. Acta
, vol.587
, pp. 60-66
-
-
Mitsuhashi, S.1
Fukushima, T.2
Arai, K.3
Tomiya, M.4
Santa, T.5
Imai, K.6
Toyo'oka, T.7
-
19
-
-
33845501438
-
Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids
-
Fukushima T., Mitsuhashi S., Tomiya M., Iyo M., Hashimoto K., Toyo'oka T. Determination of kynurenic acid in human serum and its correlation with the concentration of certain amino acids. Clin. Chim. Acta 2007, 377:174-178.
-
(2007)
Clin. Chim. Acta
, vol.377
, pp. 174-178
-
-
Fukushima, T.1
Mitsuhashi, S.2
Tomiya, M.3
Iyo, M.4
Hashimoto, K.5
Toyo'oka, T.6
-
20
-
-
47649118263
-
Simultaneous determination of kynurenine and kynurenic acid concentrations in human serum by HPLC with dual wavelengths fluorescence detection
-
Xiao L.D., Luo X.B., Pi L.G., Tang A.G., Xiao L.D. Simultaneous determination of kynurenine and kynurenic acid concentrations in human serum by HPLC with dual wavelengths fluorescence detection. Clin. Chim. Acta 2008, 395:178-180.
-
(2008)
Clin. Chim. Acta
, vol.395
, pp. 178-180
-
-
Xiao, L.D.1
Luo, X.B.2
Pi, L.G.3
Tang, A.G.4
Xiao, L.D.5
-
21
-
-
60949112945
-
More rapid and sensitive method for simultaneous determination of tryptophan and kynurenic acid by HPLC
-
Pi L.G., Tang A.G., Mo X.M., Luo X.B., Ao X. More rapid and sensitive method for simultaneous determination of tryptophan and kynurenic acid by HPLC. Clin. Biochem. 2009, 42:420-425.
-
(2009)
Clin. Biochem.
, vol.42
, pp. 420-425
-
-
Pi, L.G.1
Tang, A.G.2
Mo, X.M.3
Luo, X.B.4
Ao, X.5
-
22
-
-
65549116075
-
Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: a comparative study between enantiomers
-
Fukushima T., Sone Y., Mitsuhashi S., Tomiya M., Toyo'oka T. Alteration of kynurenic acid concentration in rat plasma following optically pure kynurenine administration: a comparative study between enantiomers. Chirality 2009, 21:468-472.
-
(2009)
Chirality
, vol.21
, pp. 468-472
-
-
Fukushima, T.1
Sone, Y.2
Mitsuhashi, S.3
Tomiya, M.4
Toyo'oka, T.5
-
23
-
-
0013601485
-
Effects of kynurenine and probenecid on plasma and brain tissue concentrations of kynurenic acid
-
Vecsei L., Miller J., MacGarvey U., Beal M.F. Effects of kynurenine and probenecid on plasma and brain tissue concentrations of kynurenic acid. Neurodegeneration 1992, 1:17-26.
-
(1992)
Neurodegeneration
, vol.1
, pp. 17-26
-
-
Vecsei, L.1
Miller, J.2
MacGarvey, U.3
Beal, M.F.4
-
24
-
-
0037175422
-
Quantitation of tryptophan, kynurenine and kynurenic acid in human plasma by capillary liquid chromatography-electrospray ionization tandem mass spectrometry
-
Amirkhani A., Heldin E., Markides K.E., Bergquist J. Quantitation of tryptophan, kynurenine and kynurenic acid in human plasma by capillary liquid chromatography-electrospray ionization tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2002, 780:381-387.
-
(2002)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.780
, pp. 381-387
-
-
Amirkhani, A.1
Heldin, E.2
Markides, K.E.3
Bergquist, J.4
-
25
-
-
23644445230
-
Interferon-beta affects the tryptophan metabolism in multiple sclerosis patients
-
Amirkhani A., Rajda C., Arvidsson B., Bencsik K., Boda K., Seres E., Markides K.E., Vecsei L., Bergquist J. Interferon-beta affects the tryptophan metabolism in multiple sclerosis patients. Eur. J. Neurol. 2005, 12:625-631.
-
(2005)
Eur. J. Neurol.
, vol.12
, pp. 625-631
-
-
Amirkhani, A.1
Rajda, C.2
Arvidsson, B.3
Bencsik, K.4
Boda, K.5
Seres, E.6
Markides, K.E.7
Vecsei, L.8
Bergquist, J.9
-
26
-
-
42749093500
-
Simultaneous measurement of tryptophan and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry
-
Yamada K., Miyazaki T., Shibata T., Hara N., Tsuchiya M. Simultaneous measurement of tryptophan and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2008, 867:57-61.
-
(2008)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.867
, pp. 57-61
-
-
Yamada, K.1
Miyazaki, T.2
Shibata, T.3
Hara, N.4
Tsuchiya, M.5
-
27
-
-
60449106709
-
Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry
-
de Jong W.H.A., Smit R., Bakker S.J.L., de Vries E.G.E., Kema I.P. Plasma tryptophan, kynurenine and 3-hydroxykynurenine measurement using automated on-line solid-phase extraction HPLC-tandem mass spectrometry. J. Chromatogr. B Analyt. Technol. Biomed. Life Sci. 2009, 877:603-609.
-
(2009)
J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.
, vol.877
, pp. 603-609
-
-
de Jong, W.H.A.1
Smit, R.2
Bakker, S.J.L.3
de Vries, E.G.E.4
Kema, I.P.5
-
28
-
-
34447254774
-
High throughput analysis of tryptophan metabolites in a complex matrix using capillary electrophoresis coupled to time-of-flight mass spectrometry
-
Arvidsson B., Johannesson N., Citterio A., Righetti P.G., Bergquist J. High throughput analysis of tryptophan metabolites in a complex matrix using capillary electrophoresis coupled to time-of-flight mass spectrometry. J. Chromatogr. A 2007, 1159:154-158.
-
(2007)
J. Chromatogr. A
, vol.1159
, pp. 154-158
-
-
Arvidsson, B.1
Johannesson, N.2
Citterio, A.3
Righetti, P.G.4
Bergquist, J.5
-
29
-
-
77955519181
-
PKSolver: an add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel
-
Zhang Y., Huo M., Zhou J., Xie S. PKSolver: an add-in program for pharmacokinetic and pharmacodynamic data analysis in Microsoft Excel. Comput. Methods Programs Biomed. 2010, 99:306-314.
-
(2010)
Comput. Methods Programs Biomed.
, vol.99
, pp. 306-314
-
-
Zhang, Y.1
Huo, M.2
Zhou, J.3
Xie, S.4
-
30
-
-
79952119038
-
Changes in the plasma concentrations of d-kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers
-
Ishii K., Ogaya T., Song Z., Iizuka H., Fukushima T. Changes in the plasma concentrations of d-kynurenine and kynurenic acid in rats after intraperitoneal administration of tryptophan enantiomers. Chirality 2010, 22:901-906.
-
(2010)
Chirality
, vol.22
, pp. 901-906
-
-
Ishii, K.1
Ogaya, T.2
Song, Z.3
Iizuka, H.4
Fukushima, T.5
|