Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor

Proceedings of the National Academy of Sciences of the United States of America

Volumn 94, Issue 11, 1997, Pages 5923-5928

  Lipton, Stuart A ^a   Kim, Won Ki ^b   Choi, Yun Beom ^a   Kumar, Shanta ^a   D'Emilia, Danielle M ^a   Rayudu, Posina V ^a   Arnelle, Derrick R ^c   Stamler, Jonathan S ^c  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b Ewha Womans University School of Medicine   (South Korea)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Excitotoxicity; Glutamate binding site of N methyl D aspartate receptor; Glycine binding site of N methyl D aspartate receptor; Homocyst(e)ine

Indexed keywords

HOMOCYSTEINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR;

AMINO ACID METABOLISM; ANIMAL TISSUE; ARTERIOSCLEROSIS; ARTICLE; BINDING SITE; CALCIUM TRANSPORT; DRUG RECEPTOR BINDING; ENDOTHELIUM CELL; ENZYME ACTIVATION; HOMOCYSTINURIA; HYPERHOMOCYSTEINEMIA; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; STROKE;

2-AMINO-5-PHOSPHONOVALERATE; 6-CYANO-7-NITROQUINOXALINE-2,3-DIONE; ADULT; ANIMALS; CELLS, CULTURED; CEREBRAL CORTEX; CHILD; DIZOCILPINE MALEATE; EMBRYO; EVOKED POTENTIALS; GLYCINE; HOMOCYSTEINE; HUMANS; KINETICS; KYNURENIC ACID; N-METHYLASPARTATE; NEURONS; NEUROTOXINS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, N-METHYL-D-ASPARTATE;

ANIMALIA;

EID: 0030915272     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.94.11.5923     Document Type: Article

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