Abnormal Ca2+-calmodulin-dependent protein kinase II function mediates synaptic and motor deficits in experimental parkinsonism

Journal of Neuroscience

Volumn 24, Issue 23, 2004, Pages 5283-5291

  Picconi, Barbara ^a,b   Gardoni, Fabrizio ^c   Centonze, Diego ^a,b   Mauceri, Daniela ^c   Cenci, M Angela ^d   Bernardi, Giorgio ^a,b   Calabresi, Paolo ^a,b   Di Luca, Monica ^c  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^c UNIVERSITY OF MILAN   (Italy)

^d LUND UNIVERSITY   (Sweden)

Author keywords

6 OHDA; CaMKII; LTP; Parkinson's disease; Rat; Striatum

Indexed keywords

8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; BENZAZEPINE DERIVATIVE; DOPAMINE; KN 92; LEVODOPA; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2A; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 2B; POSTSYNAPTIC DENSITY PROTEIN 95; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RECEPTOR SUBUNIT; SULPIRIDE; UNCLASSIFIED DRUG; AUTOCAMTIDE 2; AUTOCAMTIDE-2; BENZYLAMINE DERIVATIVE; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; DLGH4 PROTEIN, RAT; ENZYME INHIBITOR; MEMBRANE PROTEIN; NERVE PROTEIN; NR2A NMDA RECEPTOR; NR2B NMDA RECEPTOR; OXIDOPAMINE; PEPTIDE; POSTSYNAPTIC DENSITY PROTEINS; PROTEIN KINASE (CALCIUM,CALMODULIN); SIGNAL PEPTIDE; SULFONAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPHOSPHORYLATION; BRAIN CORTEX; CONTROLLED STUDY; CORPUS STRIATUM; DENERVATION; DOPAMINE RELEASE; ENZYME ANALYSIS; EXPERIMENTAL RAT; LONG TERM POTENTIATION; MALE; MOTOR DYSFUNCTION; NERVE CELL PLASTICITY; NONHUMAN; PARKINSONISM; PATHOGENESIS; POSTSYNAPTIC INHIBITION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; RAT; REGULATORY MECHANISM; SYNAPTIC MEMBRANE; ANIMAL; DISEASE MODEL; DRUG EFFECT; ENZYMOLOGY; METABOLISM; MOTOR ACTIVITY; PHOSPHORYLATION; SYNAPTIC TRANSMISSION; WISTAR RAT;

ANIMALS; BENZYLAMINES; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CORPUS STRIATUM; DENERVATION; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LEVODOPA; MALE; MEMBRANE PROTEINS; MOTOR ACTIVITY; NERVE TISSUE PROTEINS; NEURONAL PLASTICITY; OXIDOPAMINE; PARKINSONIAN DISORDERS; PEPTIDES; PHOSPHORYLATION; RATS; RATS, WISTAR; RECEPTORS, N-METHYL-D-ASPARTATE; SULFONAMIDES; SYNAPTIC TRANSMISSION;

EID: 2942586826     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1224-04.2004     Document Type: Article

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