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Volumn 125, Issue 1, 2013, Pages 1-17

Advances in our understanding of diabetic retinopathy

Author keywords

Diabetes; Diabetic retinopathy; Retina; Visual loss

Indexed keywords

ACETAZOLAMIDE; BEVACIZUMAB; BRADYKININ ANTAGONIST; CORTICOSTEROID; DEXAMETHASONE; FENOFIBRATE; FLUOCINOLONE; RANIBIZUMAB; RECOMBINANT ERYTHROPOIETIN; RECOMBINANT TUMOR NECROSIS FACTOR ALPHA; RECOMBINANT VASCULOTROPIN; SIMVASTATIN; TRIAMCINOLONE; VASCULOTROPIN;

EID: 84875586101     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20120588     Document Type: Review
Times cited : (139)

References (203)
  • 1
    • 4644240373 scopus 로고    scopus 로고
    • Global prevalence of diabetes: estimates for the year 2000 and projections for 2030
    • Rathmann, W. and Giani, G. (2004) Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care 27, 2568-2569
    • (2004) Diabetes Care , vol.27 , pp. 2568-2569
    • Rathmann, W.1    Giani, G.2
  • 2
    • 84863807894 scopus 로고    scopus 로고
    • Increased circulating levels of SDF-1 (CXCL12) in type 2 diabetic patients are correlated to disease state but are unrelated to polymorphism of the SDF-1beta gene in the Iranian population
    • Derakhshan, R., Arababadi, M. K., Ahmadi, Z., Karimabad, M. N., Salehabadi, V. A., Abedinzadeh, M., Khorramdelazad, H., Balaei, P., Kennedy, D. and Hassanshahi, G. (2012) Increased circulating levels of SDF-1 (CXCL12) in type 2 diabetic patients are correlated to disease state but are unrelated to polymorphism of the SDF-1beta gene in the Iranian population. Inflammation 35, 900-904
    • (2012) Inflammation , vol.35 , pp. 900-904
    • Derakhshan, R.1    Arababadi, M.K.2    Ahmadi, Z.3    Karimabad, M.N.4    Salehabadi, V.A.5    Abedinzadeh, M.6    Khorramdelazad, H.7    Balaei, P.8    Kennedy, D.9    Hassanshahi, G.10
  • 4
    • 79954486705 scopus 로고    scopus 로고
    • The Association of Public Health Observatories (APHO) Diabetes Prevalence Model: estimates of total diabetes prevalence for England, 2010-2030
    • Holman, N., Forouhi, N. G., Goyder, E. and Wild, S. H. (2011) The Association of Public Health Observatories (APHO) Diabetes Prevalence Model: estimates of total diabetes prevalence for England, 2010-2030. Diabetic Med. 28, 575-582
    • (2011) Diabetic Med. , vol.28 , pp. 575-582
    • Holman, N.1    Forouhi, N.G.2    Goyder, E.3    Wild, S.H.4
  • 5
    • 0024430867 scopus 로고
    • The Wisconsin epidemiological study of diabetic retinopathy: a review
    • Klein, R., Klein, B. E. and Moss, S. E. (1989) The Wisconsin epidemiological study of diabetic retinopathy: a review. Diabetes Metab. Rev. 5, 559-570
    • (1989) Diabetes Metab. Rev. , vol.5 , pp. 559-570
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3
  • 9
    • 84857115824 scopus 로고    scopus 로고
    • Prevalence of diabetic macular oedema and related health and social care resource use in England
    • Minassian, D. C., Owens, D. R. and Reidy, A. (2012) Prevalence of diabetic macular oedema and related health and social care resource use in England. Br. J. Ophthalmol. 96, 345-349
    • (2012) Br. J. Ophthalmol. , vol.96 , pp. 345-349
    • Minassian, D.C.1    Owens, D.R.2    Reidy, A.3
  • 10
    • 77949359460 scopus 로고    scopus 로고
    • Diabetic retinopathy screening: a systematic review of the economic evidence
    • Jones, S. and Edwards, R. T. (2010) Diabetic retinopathy screening: a systematic review of the economic evidence. Diabetic Med. 27, 249-256
    • (2010) Diabetic Med. , vol.27 , pp. 249-256
    • Jones, S.1    Edwards, R.T.2
  • 12
    • 0025892104 scopus 로고
    • Early photocoagulation for diabetic retinopathy
    • Early Treatment Diabetic Retinopathy Study Research Group
    • Early Treatment Diabetic Retinopathy Study Research Group (1991) Early photocoagulation for diabetic retinopathy. ETDRS report number 9. Ophthalmology 98, 766-785
    • (1991) ETDRS report number 9. Ophthalmology , vol.98 , pp. 766-785
  • 13
    • 33947532777 scopus 로고    scopus 로고
    • Pathophysiology of diabetic macular edema
    • Joussen, A. M., Smyth, N. and Niessen, C. (2007) Pathophysiology of diabetic macular edema. Dev.Ophthalmol. 39, 1-12
    • (2007) Dev.Ophthalmol. , vol.39 , pp. 1-12
    • Joussen, A.M.1    Smyth, N.2    Niessen, C.3
  • 14
    • 0027370108 scopus 로고
    • The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus
    • Diabetes Control and Complications Trial Research Group
    • Diabetes Control and Complications Trial Research Group (1993) The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. N. Engl. J. Med. 329, 977-986
    • (1993) N. Engl. J. Med. , vol.329 , pp. 977-986
  • 15
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group (1998) Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 352, 854-865
    • (1998) Lancet , vol.352 , pp. 854-865
  • 16
    • 0142087597 scopus 로고    scopus 로고
    • Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study
    • The Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group
    • The Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group (2003) Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: the Epidemiology of Diabetes Interventions and Complications (EDIC) study. JAMA, J. Am. Med. Assoc. 290, 2159-2167
    • (2003) JAMA, J. Am. Med. Assoc. , vol.290 , pp. 2159-2167
  • 17
    • 0023641117 scopus 로고
    • Progression of incipient diabetic retinopathy during good glycemic control
    • Engerman, R. L. and Kern, T. S. (1987) Progression of incipient diabetic retinopathy during good glycemic control. Diabetes 36, 808-812
    • (1987) Diabetes , vol.36 , pp. 808-812
    • Engerman, R.L.1    Kern, T.S.2
  • 19
    • 28044452217 scopus 로고    scopus 로고
    • Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial
    • Keech, A., Simes, R. J., Barter, P., Best, J., Scott, R., Taskinen, M. R., Forder, P., Pillai, A., Davis, T., Glasziou, P. et al. (2005) Effects of long-term fenofibrate therapy on cardiovascular events in 9795 people with type 2 diabetes mellitus (the FIELD study): randomised controlled trial. Lancet 366, 1849-1861
    • (2005) Lancet , vol.366 , pp. 1849-1861
    • Keech, A.1    Simes, R.J.2    Barter, P.3    Best, J.4    Scott, R.5    Taskinen, M.R.6    Forder, P.7    Pillai, A.8    Davis, T.9    Glasziou, P.10
  • 20
    • 77955585592 scopus 로고    scopus 로고
    • Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial
    • Ismail-Beigi, F., Craven, T., Banerji, M. A., Basile, J., Calles, J., Cohen, R. M., Cuddihy, R., Cushman, W. C., Genuth, S., Grimm, R. H. et al. (2010) Effect of intensive treatment of hyperglycaemia on microvascular outcomes in type 2 diabetes: an analysis of the ACCORD randomised trial. Lancet 376, 419-430
    • (2010) Lancet , vol.376 , pp. 419-430
    • Ismail-Beigi, F.1    Craven, T.2    Banerji, M.A.3    Basile, J.4    Calles, J.5    Cohen, R.M.6    Cuddihy, R.7    Cushman, W.C.8    Genuth, S.9    Grimm, R.H.10
  • 21
    • 0036180956 scopus 로고    scopus 로고
    • Simvastatin retards progression of retinopathy in diabetic patients with hypercholesterolemia
    • Sen, K., Misra, A., Kumar, A. and Pandey, R. M. (2002) Simvastatin retards progression of retinopathy in diabetic patients with hypercholesterolemia. Diabetes Res. Clin. Pract. 56, 1-11
    • (2002) Diabetes Res. Clin. Pract. , vol.56 , pp. 1-11
    • Sen, K.1    Misra, A.2    Kumar, A.3    Pandey, R.M.4
  • 22
    • 84862734043 scopus 로고    scopus 로고
    • Fenofibrate: a potential systemic treatment for diabetic retinopathy?
    • Wong, T. Y., Simo, R. and Mitchell, P. (2012) Fenofibrate: a potential systemic treatment for diabetic retinopathy? Am. J. Ophthalmol 154, 6-12
    • (2012) Am. J. Ophthalmol , vol.154 , pp. 6-12
    • Wong, T.Y.1    Simo, R.2    Mitchell, P.3
  • 23
    • 0032511580 scopus 로고    scopus 로고
    • Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38. Br. Med. J. 317, 703-713
    • (1998) Br. Med. J. , vol.317 , pp. 703-713
  • 26
    • 79951689932 scopus 로고    scopus 로고
    • Targeting the pathophysiology of diabetic macular edema
    • Romero-Aroca, P. (2010) Targeting the pathophysiology of diabetic macular edema. Diabetes Care 33, 2484-2485
    • (2010) Diabetes Care , vol.33 , pp. 2484-2485
    • Romero-Aroca, P.1
  • 27
    • 84875532294 scopus 로고    scopus 로고
    • A prospective, non comparative, multicenter study to investigate the effect of cadexomer iodine on bioburden load and other wound characteristics in diabetic foot ulcers
    • doi: 10.1111/j.1742-481X.2012.01109.x
    • Schwartz, J. A., Lantis, II, J. C., Gendics, C., Fuller, A. M., Payne, W. and Ochs, D. (2012) A prospective, non comparative, multicenter study to investigate the effect of cadexomer iodine on bioburden load and other wound characteristics in diabetic foot ulcers. Int. Wound J., doi: 10.1111/j.1742-481X.2012.01109.x
    • (2012) Int. Wound J.
    • Schwartz, J.A.1    Lantis, J.C.2    Gendics, C.3    Fuller, A.M.4    Payne, W.5    Ochs, D.6
  • 28
    • 77958481810 scopus 로고    scopus 로고
    • Genetics of diabetes complications
    • Doria, A. (2010) Genetics of diabetes complications. Curr. Diab. Rep. 10, 467-475
    • (2010) Curr. Diab. Rep. , vol.10 , pp. 467-475
    • Doria, A.1
  • 29
    • 78650694320 scopus 로고    scopus 로고
    • Epigenetics: mechanisms and implications for diabetic complications
    • Cooper, M. E. and El-Osta, A. (2010) Epigenetics: mechanisms and implications for diabetic complications. Circ. Res. 107, 1403-1413
    • (2010) Circ. Res. , vol.107 , pp. 1403-1413
    • Cooper, M.E.1    El-Osta, A.2
  • 30
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El-Osta, A., Brasacchio, D., Yao, D., Pocai, A., Jones, P. L., Roeder, R. G., Cooper, M. E. and Brownlee, M. (2008) Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J. Exp. Med. 205, 2409-2417
    • (2008) J. Exp. Med. , vol.205 , pp. 2409-2417
    • El-Osta, A.1    Brasacchio, D.2    Yao, D.3    Pocai, A.4    Jones, P.L.5    Roeder, R.G.6    Cooper, M.E.7    Brownlee, M.8
  • 31
    • 78349297565 scopus 로고    scopus 로고
    • Oxidative stress and diabetic complications
    • Giacco, F. and Brownlee, M. (2010) Oxidative stress and diabetic complications. Circ. Res. 107, 1058-1070
    • (2010) Circ. Res. , vol.107 , pp. 1058-1070
    • Giacco, F.1    Brownlee, M.2
  • 32
    • 77953860649 scopus 로고    scopus 로고
    • The role of epigenetics in the pathology of diabetic complications
    • Villeneuve, L. M. and Natarajan, R. (2010) The role of epigenetics in the pathology of diabetic complications. Am. J. Physiol. Renal Physiol. 299, F14-F25
    • (2010) Am. J. Physiol. Renal Physiol. , vol.299
    • Villeneuve, L.M.1    Natarajan, R.2
  • 33
    • 84864389693 scopus 로고    scopus 로고
    • Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC)
    • Kadiyala, C. S., Zheng, L., Du, Y., Yohannes, E., Kao, H. Y., Miyagi, M. and Kern, T. S. (2012) Acetylation of retinal histones in diabetes increases inflammatory proteins: effects of minocycline and manipulation of histone acetyltransferase (HAT) and histone deacetylase (HDAC). J. Biol. Chem. 287, 25869-25880
    • (2012) J. Biol. Chem. , vol.287 , pp. 25869-25880
    • Kadiyala, C.S.1    Zheng, L.2    Du, Y.3    Yohannes, E.4    Kao, H.Y.5    Miyagi, M.6    Kern, T.S.7
  • 35
    • 0028998575 scopus 로고
    • Vascular lesions in diabetes are distributed non-uniformly within the retina
    • Kern, T. S. and Engerman, R. L. (1995) Vascular lesions in diabetes are distributed non-uniformly within the retina. Exp. Eye Res. 60, 545-549
    • (1995) Exp. Eye Res. , vol.60 , pp. 545-549
    • Kern, T.S.1    Engerman, R.L.2
  • 36
    • 0029761062 scopus 로고    scopus 로고
    • A mouse model of diabetic retinopathy
    • Kern, T. S. and Engerman, R. L. (1996) A mouse model of diabetic retinopathy. Arch. Ophthalmol. 114, 986-990
    • (1996) Arch. Ophthalmol. , vol.114 , pp. 986-990
    • Kern, T.S.1    Engerman, R.L.2
  • 37
    • 0029128077 scopus 로고
    • Retinopathy in animal models of diabetes
    • Engerman, R. L. and Kern, T. S. (1995) Retinopathy in animal models of diabetes. Diabetes Metab. Rev. 11, 109-120
    • (1995) Diabetes Metab. Rev. , vol.11 , pp. 109-120
    • Engerman, R.L.1    Kern, T.S.2
  • 38
    • 33847261189 scopus 로고    scopus 로고
    • Arteriolar involvement in the microvascular lesions of diabetic retinopathy: implications for pathogenesis
    • Gardiner, T. A., Archer, D. B., Curtis, T. M. and Stitt, A. W. (2007) Arteriolar involvement in the microvascular lesions of diabetic retinopathy: implications for pathogenesis. Microcirculation 14, 25-38
    • (2007) Microcirculation , vol.14 , pp. 25-38
    • Gardiner, T.A.1    Archer, D.B.2    Curtis, T.M.3    Stitt, A.W.4
  • 39
    • 0028123510 scopus 로고
    • Diabetic retinopathy: quantitative variation in capillary basement membrane thickening in arterial or venous environments
    • Stitt, A. W., Anderson, H. R., Gardiner, T. A. and Archer, D. B. (1994) Diabetic retinopathy: quantitative variation in capillary basement membrane thickening in arterial or venous environments. Br. J. Ophthalmol. 78, 133-137
    • (1994) Br. J. Ophthalmol. , vol.78 , pp. 133-137
    • Stitt, A.W.1    Anderson, H.R.2    Gardiner, T.A.3    Archer, D.B.4
  • 41
    • 0028120769 scopus 로고
    • Increased expression of basement membrane collagen in human diabetic retinopathy
    • Roy, S., Maiello, M. and Lorenzi, M. (1994) Increased expression of basement membrane collagen in human diabetic retinopathy. J. Clin. Invest. 93, 438-442
    • (1994) J. Clin. Invest. , vol.93 , pp. 438-442
    • Roy, S.1    Maiello, M.2    Lorenzi, M.3
  • 42
    • 0036210557 scopus 로고    scopus 로고
    • Pericyte adhesion is impaired on extracellular matrix produced by endothelial cells in high hexose concentrations
    • Beltramo, E., Pomero, F., Allione, A., D'Alu, F., Ponte, E. and Porta, M. (2002) Pericyte adhesion is impaired on extracellular matrix produced by endothelial cells in high hexose concentrations. Diabetologia 45, 416-419
    • (2002) Diabetologia , vol.45 , pp. 416-419
    • Beltramo, E.1    Pomero, F.2    Allione, A.3    D'Alu, F.4    Ponte, E.5    Porta, M.6
  • 43
    • 0036247573 scopus 로고    scopus 로고
    • High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells
    • Padayatti, P. S., Jiang, C., Glomb, M. A., Uchida, K. and Nagaraj, R. H. (2001) High concentrations of glucose induce synthesis of argpyrimidine in retinal endothelial cells. Curr. Eye Res. 23, 106-115
    • (2001) Curr. Eye Res. , vol.23 , pp. 106-115
    • Padayatti, P.S.1    Jiang, C.2    Glomb, M.A.3    Uchida, K.4    Nagaraj, R.H.5
  • 44
    • 19944367877 scopus 로고    scopus 로고
    • Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor
    • Stitt, A. W., Hughes, S. J., Canning, P., Lynch, O., Cox, O., Frizzell, N., Thorpe, S. R., Cotter, T. G., Curtis, T. M. and Gardiner, T. A. (2004) Substrates modified by advanced glycation end-products cause dysfunction and death in retinal pericytes by reducing survival signals mediated by platelet-derived growth factor. Diabetologia 47, 1735-1746
    • (2004) Diabetologia , vol.47 , pp. 1735-1746
    • Stitt, A.W.1    Hughes, S.J.2    Canning, P.3    Lynch, O.4    Cox, O.5    Frizzell, N.6    Thorpe, S.R.7    Cotter, T.G.8    Curtis, T.M.9    Gardiner, T.A.10
  • 45
    • 77954955043 scopus 로고    scopus 로고
    • Aging increases retinal vascular lesions characteristic of early diabetic retinopathy
    • Roy, S., Tonkiss, J. and Roy, S. (2010) Aging increases retinal vascular lesions characteristic of early diabetic retinopathy. Biogerontology 11, 447-455
    • (2010) Biogerontology , vol.11 , pp. 447-455
    • Roy, S.1    Tonkiss, J.2    Roy, S.3
  • 48
    • 0030658055 scopus 로고    scopus 로고
    • Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility
    • Mott, J. D., Khalifah, R. G., Nagase, H., Shield, III, C. F., Hudson, J. K. and Hudson, B. G. (1997) Nonenzymatic glycation of type IV collagen and matrix metalloproteinase susceptibility. Kidney Int. 52, 1302-1312
    • (1997) Kidney Int. , vol.52 , pp. 1302-1312
    • Mott, J.D.1    Khalifah, R.G.2    Nagase, H.3    Shield, C.F.4    Hudson, J.K.5    Hudson, B.G.6
  • 49
    • 0141961133 scopus 로고    scopus 로고
    • Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes
    • Gardiner, T. A., Anderson, H. R. and Stitt, A. W. (2003) Inhibition of advanced glycation end-products protects against retinal capillary basement membrane expansion during long-term diabetes. J. Pathol. 201, 328-333
    • (2003) J. Pathol. , vol.201 , pp. 328-333
    • Gardiner, T.A.1    Anderson, H.R.2    Stitt, A.W.3
  • 50
    • 0027958305 scopus 로고
    • Selective loss of vascular smooth muscle cells in the retinal microcirculation of diabetic dogs
    • Gardiner, T. A., Stitt, A. W., Anderson, H. R. and Archer, D. B. (1994) Selective loss of vascular smooth muscle cells in the retinal microcirculation of diabetic dogs. Br. J. Ophthalmol. 78, 54-60
    • (1994) Br. J. Ophthalmol. , vol.78 , pp. 54-60
    • Gardiner, T.A.1    Stitt, A.W.2    Anderson, H.R.3    Archer, D.B.4
  • 51
    • 0029973474 scopus 로고    scopus 로고
    • Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy
    • Mizutani, M., Kern, T. S. and Lorenzi, M. (1996) Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. J. Clin.Invest. 97, 2883-2890
    • (1996) J. Clin.Invest. , vol.97 , pp. 2883-2890
    • Mizutani, M.1    Kern, T.S.2    Lorenzi, M.3
  • 52
    • 50549218525 scopus 로고
    • The limited in vitro lifetime of human diploid cell strains
    • Hayflick, L. (1965) The limited in vitro lifetime of human diploid cell strains. Exp. Cell Res. 37, 614-636
    • (1965) Exp. Cell Res. , vol.37 , pp. 614-636
    • Hayflick, L.1
  • 54
    • 0037188926 scopus 로고    scopus 로고
    • Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells
    • Chen, J., Brodsky, S. V., Goligorsky, D. M., Hampel, D. J., Li, H., Gross, S. S. and Goligorsky, M. S. (2002) Glycated collagen I induces premature senescence-like phenotypic changes in endothelial cells. Circ. Res. 90, 1290-1298
    • (2002) Circ. Res. , vol.90 , pp. 1290-1298
    • Chen, J.1    Brodsky, S.V.2    Goligorsky, D.M.3    Hampel, D.J.4    Li, H.5    Gross, S.S.6    Goligorsky, M.S.7
  • 55
    • 33644851090 scopus 로고    scopus 로고
    • Towards newer molecular targets for chronic diabetic complications
    • Khan, Z. A., Farhangkhoee, H. and Chakrabarti, S. (2006) Towards newer molecular targets for chronic diabetic complications. Curr. Vasc. Pharmacol. 4, 45-57
    • (2006) Curr. Vasc. Pharmacol. , vol.4 , pp. 45-57
    • Khan, Z.A.1    Farhangkhoee, H.2    Chakrabarti, S.3
  • 56
    • 0036152086 scopus 로고    scopus 로고
    • Development of the mouse retinal vasculature: angiogenesis versus vasculogenesis
    • Fruttiger, M. (2002) Development of the mouse retinal vasculature: angiogenesis versus vasculogenesis. Invest. Ophthalmol. Visual Sci. 43, 522-527
    • (2002) Invest. Ophthalmol. Visual Sci. , vol.43 , pp. 522-527
    • Fruttiger, M.1
  • 58
    • 0346670120 scopus 로고    scopus 로고
    • Sources of PDGF expression in murine retina and the effect of short-term diabetes
    • Cox, O., Stitt, A. W., Simpson, D. A. and Gardiner, T. A. (2003) Sources of PDGF expression in murine retina and the effect of short-term diabetes. Mol. Vision 10, 665-672
    • (2003) Mol. Vision , vol.10 , pp. 665-672
    • Cox, O.1    Stitt, A.W.2    Simpson, D.A.3    Gardiner, T.A.4
  • 60
    • 0014787033 scopus 로고
    • Fluorescein angiography of the fundus in diabetic retinopathy
    • Kohner, E. M. and Dollery, C. T. (1970) Fluorescein angiography of the fundus in diabetic retinopathy. Br. Med. Bull. 26, 166-170
    • (1970) Br. Med. Bull. , vol.26 , pp. 166-170
    • Kohner, E.M.1    Dollery, C.T.2
  • 61
    • 0014748128 scopus 로고
    • Correlation of fluorescein angiogram and retinal digest in diabetic retinopathy
    • Kohner, E. M. and Henkind, P. (1970) Correlation of fluorescein angiogram and retinal digest in diabetic retinopathy. Am. J. Ophthalmol. 69, 403-414
    • (1970) Am. J. Ophthalmol. , vol.69 , pp. 403-414
    • Kohner, E.M.1    Henkind, P.2
  • 63
    • 0035237469 scopus 로고    scopus 로고
    • Retinal vascular changes and systemic diseases: corrosion cast demonstration
    • Amemiya, T. and Bhutto, I. A. (2001) Retinal vascular changes and systemic diseases: corrosion cast demonstration. Ital. J. Anat. Embryol. 106, 237-244
    • (2001) Ital. J. Anat. Embryol. , vol.106 , pp. 237-244
    • Amemiya, T.1    Bhutto, I.A.2
  • 65
    • 0020525279 scopus 로고
    • Occlusive thromboaortopathy (Takayasu's disease): cervical arterial stenoses, retinal arterial pressure, retinal microaneurysms and prognosis
    • Ishikawa, K., Uyama, M. and Asayama, K. (1983) Occlusive thromboaortopathy (Takayasu's disease): cervical arterial stenoses, retinal arterial pressure, retinal microaneurysms and prognosis. Stroke 14, 730-735
    • (1983) Stroke , vol.14 , pp. 730-735
    • Ishikawa, K.1    Uyama, M.2    Asayama, K.3
  • 66
  • 67
    • 0028922544 scopus 로고
    • Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients
    • Stitt, A. W., Gardiner, T. A. and Archer, D. B. (1995) Histological and ultrastructural investigation of retinal microaneurysm development in diabetic patients. Br. J. Ophthalmol. 79, 362-367
    • (1995) Br. J. Ophthalmol. , vol.79 , pp. 362-367
    • Stitt, A.W.1    Gardiner, T.A.2    Archer, D.B.3
  • 68
    • 0014019536 scopus 로고
    • Diabetic retinopathy
    • Yanoff, M. (1966) Diabetic retinopathy. N. Engl. J. Med. 274, 1344-1349
    • (1966) N. Engl. J. Med. , vol.274 , pp. 1344-1349
    • Yanoff, M.1
  • 69
  • 71
    • 0022580197 scopus 로고
    • Color vision defects in early diabetic retinopathy
    • Roy, M. S., Gunkel, R. D. and Podgor, M. J. (1986) Color vision defects in early diabetic retinopathy. Arch. Ophthalmol. 104, 225-228
    • (1986) Arch. Ophthalmol. , vol.104 , pp. 225-228
    • Roy, M.S.1    Gunkel, R.D.2    Podgor, M.J.3
  • 73
    • 0002730499 scopus 로고
    • Electroretinogram in diabetic retinopathy
    • Yonemura, D., Aoki, T. and Tsuzuki, K. (1962) Electroretinogram in diabetic retinopathy. Arch. Ophthalmol. 68, 19-24
    • (1962) Arch. Ophthalmol. , vol.68 , pp. 19-24
    • Yonemura, D.1    Aoki, T.2    Tsuzuki, K.3
  • 75
    • 33746729952 scopus 로고    scopus 로고
    • Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita-diabetic mouse retinas
    • Gastinger, M. J., Singh, R. S. and Barber, A. J. (2006) Loss of cholinergic and dopaminergic amacrine cells in streptozotocin-diabetic rat and Ins2Akita-diabetic mouse retinas. Invest. Ophthalmol. Visual Sci. 47, 3143-3150
    • (2006) Invest. Ophthalmol. Visual Sci. , vol.47 , pp. 3143-3150
    • Gastinger, M.J.1    Singh, R.S.2    Barber, A.J.3
  • 77
    • 0141594635 scopus 로고    scopus 로고
    • Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina
    • Park, S. H., Park, J. W., Park, S. J., Kim, K. Y., Chung, J. W., Chun, M. H. and Oh, S. J. (2003) Apoptotic death of photoreceptors in the streptozotocin-induced diabetic rat retina. Diabetologia 46, 1260-1268
    • (2003) Diabetologia , vol.46 , pp. 1260-1268
    • Park, S.H.1    Park, J.W.2    Park, S.J.3    Kim, K.Y.4    Chung, J.W.5    Chun, M.H.6    Oh, S.J.7
  • 78
    • 9444287093 scopus 로고    scopus 로고
    • Paired-flash identification of rod and cone dysfunction in the diabetic rat
    • Phipps, J. A., Fletcher, E. L. and Vingrys, A. J. (2004) Paired-flash identification of rod and cone dysfunction in the diabetic rat. Invest. Ophthalmol. Visual Sci. 45, 4592-4600
    • (2004) Invest. Ophthalmol. Visual Sci. , vol.45 , pp. 4592-4600
    • Phipps, J.A.1    Fletcher, E.L.2    Vingrys, A.J.3
  • 79
    • 0031594369 scopus 로고    scopus 로고
    • Muller cell changes in human diabetic retinopathy
    • Mizutani, M., Gerhardinger, C. and Lorenzi, M. (1998) Muller cell changes in human diabetic retinopathy. Diabetes 47, 445-449
    • (1998) Diabetes , vol.47 , pp. 445-449
    • Mizutani, M.1    Gerhardinger, C.2    Lorenzi, M.3
  • 80
    • 0036981941 scopus 로고    scopus 로고
    • Diabetes-induced dysfunction of retinal Muller cells
    • Puro, D. G. (2002) Diabetes-induced dysfunction of retinal Muller cells. Trans. Am. Ophthalmol. Soc. 100, 339-352
    • (2002) Trans. Am. Ophthalmol. Soc. , vol.100 , pp. 339-352
    • Puro, D.G.1
  • 81
    • 0031919598 scopus 로고    scopus 로고
    • Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy
    • Lieth, E., Barber, A. J., Xu, B., Dice, C., Ratz, M. J., Tanase, D. and Strother, J. M. (1998) Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy. Diabetes 47, 815-820
    • (1998) Diabetes , vol.47 , pp. 815-820
    • Lieth, E.1    Barber, A.J.2    Xu, B.3    Dice, C.4    Ratz, M.J.5    Tanase, D.6    Strother, J.M.7
  • 82
    • 0035856980 scopus 로고    scopus 로고
    • Biochemistry and molecular cell biology of diabetic complications
    • Brownlee, M. (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414, 813-820
    • (2001) Nature , vol.414 , pp. 813-820
    • Brownlee, M.1
  • 85
    • 84862106027 scopus 로고    scopus 로고
    • The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial
    • Fraser, D. A., Diep, L. M., Hovden, I. A., Nilsen, K. B., Sveen, K. A., Seljeflot, I. and Hanssen, K. F. (2012) The effects of long-term oral benfotiamine supplementation on peripheral nerve function and inflammatory markers in patients with type 1 diabetes: a 24-month, double-blind, randomized, placebo-controlled trial. Diabetes Care 35, 1095-1097
    • (2012) Diabetes Care , vol.35 , pp. 1095-1097
    • Fraser, D.A.1    Diep, L.M.2    Hovden, I.A.3    Nilsen, K.B.4    Sveen, K.A.5    Seljeflot, I.6    Hanssen, K.F.7
  • 86
    • 0029038779 scopus 로고
    • Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy
    • Kohner, E. M., Patel, V. and Rassam, S. M. (1995) Role of blood flow and impaired autoregulation in the pathogenesis of diabetic retinopathy. Diabetes 44, 603-607
    • (1995) Diabetes , vol.44 , pp. 603-607
    • Kohner, E.M.1    Patel, V.2    Rassam, S.M.3
  • 87
    • 0033775426 scopus 로고    scopus 로고
    • A retinal-derived relaxing factor mediates the hypoxic vasodilation of retinal arteries
    • Delaey, C., Boussery, K. and Van, d.V. (2000) A retinal-derived relaxing factor mediates the hypoxic vasodilation of retinal arteries. Invest. Ophthalmol. Visual Sci. 41, 3555-3560
    • (2000) Invest. Ophthalmol. Visual Sci. , vol.41 , pp. 3555-3560
    • Delaey, C.1    Boussery, K.2    Van, D.V.3
  • 90
    • 0014516910 scopus 로고
    • Diameters of the retinal vessels in diabetic and normal subjects
    • Skovborg, F., Nielsen, A. V., Lauritzen, E. and Hartkopp, O. (1969) Diameters of the retinal vessels in diabetic and normal subjects. Diabetes 18, 292-298
    • (1969) Diabetes , vol.18 , pp. 292-298
    • Skovborg, F.1    Nielsen, A.V.2    Lauritzen, E.3    Hartkopp, O.4
  • 92
    • 0027755359 scopus 로고
    • The retinal blood flow in diabetes
    • Kohner, E. M. (1993) The retinal blood flow in diabetes. Diabetes Metab. 19, 401-404
    • (1993) Diabetes Metab. , vol.19 , pp. 401-404
    • Kohner, E.M.1
  • 94
    • 0030770396 scopus 로고    scopus 로고
    • Vascular endothelial growth factor and severity of nonproliferative diabetic retinopathy mediate retinal hemodynamics in vivo: a potential role for vascular endothelial growth factor in the progression of nonproliferative diabetic retinopathy
    • Clermont, A. C., Aiello, L. P., Mori, F., Aiello, L. M. and Bursell, S. E. (1997) Vascular endothelial growth factor and severity of nonproliferative diabetic retinopathy mediate retinal hemodynamics in vivo: a potential role for vascular endothelial growth factor in the progression of nonproliferative diabetic retinopathy. Am. J. Ophthalmol. 124, 433-446
    • (1997) Am. J. Ophthalmol. , vol.124 , pp. 433-446
    • Clermont, A.C.1    Aiello, L.P.2    Mori, F.3    Aiello, L.M.4    Bursell, S.E.5
  • 99
    • 0242380839 scopus 로고    scopus 로고
    • Retinal vascular abnormalities in persons with type 1 diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVIII
    • Klein, R., Klein, B. E., Moss, S. E., Wong, T. Y., Hubbard, L., Cruickshanks, K. J. and Palta, M. (2003) Retinal vascular abnormalities in persons with type 1 diabetes: the Wisconsin Epidemiologic Study of Diabetic Retinopathy: XVIII. Ophthalmology 110, 2118-2125
    • (2003) Ophthalmology , vol.110 , pp. 2118-2125
    • Klein, R.1    Klein, B.E.2    Moss, S.E.3    Wong, T.Y.4    Hubbard, L.5    Cruickshanks, K.J.6    Palta, M.7
  • 100
    • 0033018576 scopus 로고    scopus 로고
    • Ocular blood flow and associated functional deviations in diabetic retinopathy
    • Schmetterer, L. and Wolzt, M. (1999) Ocular blood flow and associated functional deviations in diabetic retinopathy. Diabetologia 42, 387-405
    • (1999) Diabetologia , vol.42 , pp. 387-405
    • Schmetterer, L.1    Wolzt, M.2
  • 101
    • 84862197250 scopus 로고    scopus 로고
    • Changes in retinal vessel diameter and incidence and progression of diabetic retinopathy
    • Klein, R., Myers, C. E., Lee, K. E., Gangnon, R. and Klein, B. E. (2012) Changes in retinal vessel diameter and incidence and progression of diabetic retinopathy. Arch Ophthalmol 130, 749-755
    • (2012) Arch Ophthalmol , vol.130 , pp. 749-755
    • Klein, R.1    Myers, C.E.2    Lee, K.E.3    Gangnon, R.4    Klein, B.E.5
  • 102
    • 0026548652 scopus 로고
    • Total retinal volumetric blood flow rate in diabetic patients with poor glycemic control
    • Grunwald, J. E., Riva, C. E., Baine, J. and Brucker, A. J. (1992) Total retinal volumetric blood flow rate in diabetic patients with poor glycemic control. Invest Ophthalmol.Visual Sci. 33, 356-363
    • (1992) Invest Ophthalmol.Visual Sci. , vol.33 , pp. 356-363
    • Grunwald, J.E.1    Riva, C.E.2    Baine, J.3    Brucker, A.J.4
  • 103
    • 79960190061 scopus 로고    scopus 로고
    • Inflammation in diabetic retinopathy
    • Tang, J. and Kern, T. S. (2011) Inflammation in diabetic retinopathy. Prog. Retin. Eye Res. 30, 343-358
    • (2011) Prog. Retin. Eye Res. , vol.30 , pp. 343-358
    • Tang, J.1    Kern, T.S.2
  • 105
    • 84871998547 scopus 로고    scopus 로고
    • Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes
    • Talahalli, R., Zarini, S., Tang, J., Li, G., Murphy, R., Kern, T. S. and Gubitosi-Klug, R. A. (2013) Leukocytes regulate retinal capillary degeneration in the diabetic mouse via generation of leukotrienes. J. Leukocyte Biol. 93, 135-143
    • (2013) J. Leukocyte Biol. , vol.93 , pp. 135-143
    • Talahalli, R.1    Zarini, S.2    Tang, J.3    Li, G.4    Murphy, R.5    Kern, T.S.6    Gubitosi-Klug, R.A.7
  • 106
    • 84870383668 scopus 로고    scopus 로고
    • Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice
    • Li, G., Veenstra, A. A., Talahalli, R. R., Wang, X., Gubitosi-Klug, R. A., Sheibani, N. and Kern, T. S. (2012) Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice. Diabetes 61, 3294-3303
    • (2012) Diabetes , vol.61 , pp. 3294-3303
    • Li, G.1    Veenstra, A.A.2    Talahalli, R.R.3    Wang, X.4    Gubitosi-Klug, R.A.5    Sheibani, N.6    Kern, T.S.7
  • 107
    • 67650227476 scopus 로고    scopus 로고
    • The transforming growth factor-ß pathway is a common target of drugs that prevent experimental diabetic retinopathy
    • Gerhardinger, C., Dagher, Z., Sebastiani, P., Park, Y. S. and Lorenzi, M. (2009) The transforming growth factor-ß pathway is a common target of drugs that prevent experimental diabetic retinopathy. Diabetes 58, 1659-1667
    • (2009) Diabetes , vol.58 , pp. 1659-1667
    • Gerhardinger, C.1    Dagher, Z.2    Sebastiani, P.3    Park, Y.S.4    Lorenzi, M.5
  • 109
    • 39049127031 scopus 로고    scopus 로고
    • Microglial activation in human diabetic retinopathy
    • Zeng, H. Y., Green, W. R. and Tso, M. O. (2008) Microglial activation in human diabetic retinopathy. Arch. Ophthalmol. 126, 227-232
    • (2008) Arch. Ophthalmol. , vol.126 , pp. 227-232
    • Zeng, H.Y.1    Green, W.R.2    Tso, M.O.3
  • 111
    • 3543043820 scopus 로고    scopus 로고
    • Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina
    • Kuiper, E. J., Witmer, A. N., Klaassen, I., Oliver, N., Goldschmeding, R. and Schlingemann, R. O. (2004) Differential expression of connective tissue growth factor in microglia and pericytes in the human diabetic retina. Br. J. Ophthalmol. 88, 1082-1087
    • (2004) Br. J. Ophthalmol. , vol.88 , pp. 1082-1087
    • Kuiper, E.J.1    Witmer, A.N.2    Klaassen, I.3    Oliver, N.4    Goldschmeding, R.5    Schlingemann, R.O.6
  • 112
  • 115
    • 0033921527 scopus 로고    scopus 로고
    • Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats
    • Zeng, X. X., Ng, Y. K. and Ling, E. A. (2000) Neuronal and microglial response in the retina of streptozotocin-induced diabetic rats. Visual Neurosci. 17, 463-471
    • (2000) Visual Neurosci. , vol.17 , pp. 463-471
    • Zeng, X.X.1    Ng, Y.K.2    Ling, E.A.3
  • 116
    • 80051599575 scopus 로고    scopus 로고
    • AGEs, RAGE, and diabetic retinopathy
    • Zong, H., Ward, M. and Stitt, A. W. (2011) AGEs, RAGE, and diabetic retinopathy. Curr. Diabetes Rep. 11, 244-252
    • (2011) Curr. Diabetes Rep. , vol.11 , pp. 244-252
    • Zong, H.1    Ward, M.2    Stitt, A.W.3
  • 118
    • 0034995073 scopus 로고    scopus 로고
    • S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
    • Donato, R. (2001) S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles. Int. J. Biochem. Cell Biol. 33, 637-668
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 637-668
    • Donato, R.1
  • 119
    • 78649333713 scopus 로고    scopus 로고
    • Hyperglycaemia-induced pro-inflammatory responses by retinal Muller glia are regulated by the receptor for advanced glycation end-products (RAGE)
    • Zong, H., Ward, M., Madden, A., Yong, P. H., Limb, G. A., Curtis, T. M. and Stitt, A. W. (2010) Hyperglycaemia-induced pro-inflammatory responses by retinal Muller glia are regulated by the receptor for advanced glycation end-products (RAGE). Diabetologia 53, 2656-2666
    • (2010) Diabetologia , vol.53 , pp. 2656-2666
    • Zong, H.1    Ward, M.2    Madden, A.3    Yong, P.H.4    Limb, G.A.5    Curtis, T.M.6    Stitt, A.W.7
  • 121
    • 83055198504 scopus 로고    scopus 로고
    • Beneficial effects of a novel RAGE inhibitor on early diabetic retinopathy and tactile allodynia
    • Li, G., Tang, J., Du, Y., Lee, C. A. and Kern, T. S. (2011) Beneficial effects of a novel RAGE inhibitor on early diabetic retinopathy and tactile allodynia. Mol. Vision 17, 3156-3165
    • (2011) Mol. Vision , vol.17 , pp. 3156-3165
    • Li, G.1    Tang, J.2    Du, Y.3    Lee, C.A.4    Kern, T.S.5
  • 122
    • 33947308813 scopus 로고    scopus 로고
    • Vascular permeability in ocular disease and the role of tight junctions
    • Erickson, K. K., Sundstrom, J. M. and Antonetti, D. A. (2007) Vascular permeability in ocular disease and the role of tight junctions. Angiogenesis. 10, 103-117
    • (2007) Angiogenesis. , vol.10 , pp. 103-117
    • Erickson, K.K.1    Sundstrom, J.M.2    Antonetti, D.A.3
  • 123
  • 125
    • 77953170750 scopus 로고    scopus 로고
    • The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier: implications for the pathogenesis of diabetic retinopathy
    • Simo, R., Villarroel, M., Corraliza, L., Hernandez, C. and Garcia-Ramirez, M. (2010) The retinal pigment epithelium: something more than a constituent of the blood-retinal barrier: implications for the pathogenesis of diabetic retinopathy. J. Biomed. Biotechnol. 2010, 190724
    • (2010) J. Biomed. Biotechnol. , vol.2010 , pp. 190724
    • Simo, R.1    Villarroel, M.2    Corraliza, L.3    Hernandez, C.4    Garcia-Ramirez, M.5
  • 126
    • 79955995693 scopus 로고    scopus 로고
    • Significance of outer blood-retina barrier breakdown in diabetes and ischemia
    • Xu, H. Z. and Le, Y. Z. (2011) Significance of outer blood-retina barrier breakdown in diabetes and ischemia. Invest. Ophthalmol. Visual Sci. 52, 2160-2164
    • (2011) Invest. Ophthalmol. Visual Sci. , vol.52 , pp. 2160-2164
    • Xu, H.Z.1    Le, Y.Z.2
  • 127
    • 78650540339 scopus 로고    scopus 로고
    • Involvement of oxidative stress and mitochondrial dysfunction in the osmotic swelling of retinal glial cells from diabetic rats
    • Krugel, K., Wurm, A., Pannicke, T., Hollborn, M., Karl, A., Wiedemann, P., Reichenbach, A., Kohen, L. and Bringmann, A. (2011) Involvement of oxidative stress and mitochondrial dysfunction in the osmotic swelling of retinal glial cells from diabetic rats. Exp. Eye Res. 92, 87-93
    • (2011) Exp. Eye Res. , vol.92 , pp. 87-93
    • Krugel, K.1    Wurm, A.2    Pannicke, T.3    Hollborn, M.4    Karl, A.5    Wiedemann, P.6    Reichenbach, A.7    Kohen, L.8    Bringmann, A.9
  • 128
    • 0346406983 scopus 로고    scopus 로고
    • Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study
    • Schram, M. T., Chaturvedi, N., Schalkwijk, C., Giorgino, F., Ebeling, P., Fuller, J. H. and Stehouwer, C. D. (2003) Vascular risk factors and markers of endothelial function as determinants of inflammatory markers in type 1 diabetes: the EURODIAB Prospective Complications Study. Diabetes Care 26, 2165-2173
    • (2003) Diabetes Care , vol.26 , pp. 2165-2173
    • Schram, M.T.1    Chaturvedi, N.2    Schalkwijk, C.3    Giorgino, F.4    Ebeling, P.5    Fuller, J.H.6    Stehouwer, C.D.7
  • 129
    • 0036861529 scopus 로고    scopus 로고
    • The role of serum lipids in exudative diabetic maculopathy: is there a place for lipid lowering therapy?
    • Chowdhury, T. A., Hopkins, D., Dodson, P. M. and Vafidis, G. C. (2002) The role of serum lipids in exudative diabetic maculopathy: is there a place for lipid lowering therapy?. Eye 16, 689-693
    • (2002) Eye , vol.16 , pp. 689-693
    • Chowdhury, T.A.1    Hopkins, D.2    Dodson, P.M.3    Vafidis, G.C.4
  • 130
    • 77951621978 scopus 로고    scopus 로고
    • Factors associated with improvement and worsening of visual acuity 2 years after focal/grid photocoagulation for diabetic macular edema
    • Aiello, L. P., Edwards, A. R., Beck, R. W., Bressler, N. M., Davis, M. D., Ferris, F., Glassman, A. R., Ip, M. S. and Miller, K. M (2010) Factors associated with improvement and worsening of visual acuity 2 years after focal/grid photocoagulation for diabetic macular edema. Ophthalmology 117, 946-953
    • (2010) Ophthalmology , vol.117 , pp. 946-953
    • Aiello, L.P.1    Edwards, A.R.2    Beck, R.W.3    Bressler, N.M.4    Davis, M.D.5    Ferris, F.6    Glassman, A.R.7    Ip, M.S.8    Miller, K.M.9
  • 133
    • 0030803023 scopus 로고    scopus 로고
    • Ocular vascular endothelial growth factor levels in diabetic rats are elevated before observable retinal proliferative changes
    • Sone, H., Kawakami, Y., Okuda, Y., Sekine, Y., Honmura, S., Matsuo, K., Segawa, T., Suzuki, H. and Yamashita, K. (1997) Ocular vascular endothelial growth factor levels in diabetic rats are elevated before observable retinal proliferative changes. Diabetologia 40, 726-730
    • (1997) Diabetologia , vol.40 , pp. 726-730
    • Sone, H.1    Kawakami, Y.2    Okuda, Y.3    Sekine, Y.4    Honmura, S.5    Matsuo, K.6    Segawa, T.7    Suzuki, H.8    Yamashita, K.9
  • 134
    • 0033939404 scopus 로고    scopus 로고
    • Plasma VEGF and soluble VEGF receptor FLT-1 in proliferative retinopathy: relationship to endothelial dysfunction and laser treatment
    • Lip, P. L., Belgore, F., Blann, A. D., Hope-Ross, M. W., Gibson, J. M. and Lip, G. Y. (2000) Plasma VEGF and soluble VEGF receptor FLT-1 in proliferative retinopathy: relationship to endothelial dysfunction and laser treatment. Invest. Ophthalmol. Visual Sci. 41, 2115-2119
    • (2000) Invest. Ophthalmol. Visual Sci. , vol.41 , pp. 2115-2119
    • Lip, P.L.1    Belgore, F.2    Blann, A.D.3    Hope-Ross, M.W.4    Gibson, J.M.5    Lip, G.Y.6
  • 138
    • 84872022283 scopus 로고    scopus 로고
    • Variants in the VEGFA gene and treatment outcome after anti-VEGF treatment for neovascular age-related macular degeneration
    • Abedi, F., Wickremasinghe, S., Richardson, A. J., Makalic, E., Schmidt, D. F., Sandhu, S. S., Baird, P. N. and Guymer, R. H. (2013) Variants in the VEGFA gene and treatment outcome after anti-VEGF treatment for neovascular age-related macular degeneration. Ophthalmology, 120, 115-121
    • (2013) Ophthalmology , vol.120 , pp. 115-121
    • Abedi, F.1    Wickremasinghe, S.2    Richardson, A.J.3    Makalic, E.4    Schmidt, D.F.5    Sandhu, S.S.6    Baird, P.N.7    Guymer, R.H.8
  • 141
    • 77952889192 scopus 로고    scopus 로고
    • A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study) 12-month data: report 2
    • Michaelides, M., Kaines, A., Hamilton, R. D., Fraser-Bell, S., Rajendram, R., Quhill, F., Boos, C. J., Xing, W., Egan, C., Peto, T. et al. (2010) A prospective randomized trial of intravitreal bevacizumab or laser therapy in the management of diabetic macular edema (BOLT study) 12-month data: report 2. Ophthalmology 117, 1078-1086
    • (2010) Ophthalmology , vol.117 , pp. 1078-1086
    • Michaelides, M.1    Kaines, A.2    Hamilton, R.D.3    Fraser-Bell, S.4    Rajendram, R.5    Quhill, F.6    Boos, C.J.7    Xing, W.8    Egan, C.9    Peto, T.10
  • 143
    • 84864473215 scopus 로고    scopus 로고
    • Cost-effectiveness analysis of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema
    • Dewan, V., Lambert, D., Edler, J., Kymes, S. and Apte, R. S. (2012) Cost-effectiveness analysis of ranibizumab plus prompt or deferred laser or triamcinolone plus prompt laser for diabetic macular edema. Ophthalmology 119, 1679-1684
    • (2012) Ophthalmology , vol.119 , pp. 1679-1684
    • Dewan, V.1    Lambert, D.2    Edler, J.3    Kymes, S.4    Apte, R.S.5
  • 144
    • 77749330682 scopus 로고    scopus 로고
    • Randomized controlled trial of an intravitreous dexamethasone drug delivery system in patients with diabetic macular edema
    • Haller, J. A., Kuppermann, B. D., Blumenkranz, M. S., Williams, G. A., Weinberg, D. V., Chou, C. and Whitcup, S. M. (2010) Randomized controlled trial of an intravitreous dexamethasone drug delivery system in patients with diabetic macular edema. Arch. Ophthalmol. 128, 289-296
    • (2010) Arch. Ophthalmol. , vol.128 , pp. 289-296
    • Haller, J.A.1    Kuppermann, B.D.2    Blumenkranz, M.S.3    Williams, G.A.4    Weinberg, D.V.5    Chou, C.6    Whitcup, S.M.7
  • 146
    • 0032214094 scopus 로고    scopus 로고
    • The role of vitrectomy for diabetic retinopathy
    • Arrigg, P. G. and Cavallerano, J. (1998) The role of vitrectomy for diabetic retinopathy. J. Am. Optom. Assoc. 69, 733-740
    • (1998) J. Am. Optom. Assoc. , vol.69 , pp. 733-740
    • Arrigg, P.G.1    Cavallerano, J.2
  • 148
    • 0034955539 scopus 로고    scopus 로고
    • Retinal photocoagulation does not influence intraocular levels of IGF-I, IGF-II and IGF-BP3 in proliferative diabetic retinopathy-evidence for combined treatment of PDR with somatostatin analogues and retinal photocoagulation?
    • Spranger, J., Mohlig, M., Osterhoff, M., Buhnen, J., Blum, W. F. and Pfeiffer, A. F. (2001) Retinal photocoagulation does not influence intraocular levels of IGF-I, IGF-II and IGF-BP3 in proliferative diabetic retinopathy-evidence for combined treatment of PDR with somatostatin analogues and retinal photocoagulation? Horm. Metab. Res. 33, 312-316
    • (2001) Horm. Metab. Res. , vol.33 , pp. 312-316
    • Spranger, J.1    Mohlig, M.2    Osterhoff, M.3    Buhnen, J.4    Blum, W.F.5    Pfeiffer, A.F.6
  • 150
    • 0031834239 scopus 로고    scopus 로고
    • A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF
    • Benjamin, LE, Hemo, I and E, K. (1998) A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF. Development 125, 1591-1598
    • (1998) Development , vol.125 , pp. 1591-1598
    • Benjamin, L.E.1    Hemo, I.E.K.2
  • 151
    • 34547702738 scopus 로고    scopus 로고
    • Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury
    • Nishijima, K., Ng, Y. S., Zhong, L., Bradley, J., Schubert, W., Jo, N., Akita, J., Samuelsson, S. J., Robinson, G. S., Adamis, A. P. and Shima, D. T. (2007) Vascular endothelial growth factor-A is a survival factor for retinal neurons and a critical neuroprotectant during the adaptive response to ischemic injury. Am. J. Pathol. 171, 53-67
    • (2007) Am. J. Pathol. , vol.171 , pp. 53-67
    • Nishijima, K.1    Ng, Y.S.2    Zhong, L.3    Bradley, J.4    Schubert, W.5    Jo, N.6    Akita, J.7    Samuelsson, S.J.8    Robinson, G.S.9    Adamis, A.P.10    Shima, D.T.11
  • 152
    • 11144348973 scopus 로고    scopus 로고
    • Development and pathology of the hyaloid, choroidal and retinal vasculature
    • Saint-Geniez, M. and D'Amore, P. A. (2004) Development and pathology of the hyaloid, choroidal and retinal vasculature. Int. J. Dev. Biol. 48, 1045-1058
    • (2004) Int. J. Dev. Biol. , vol.48 , pp. 1045-1058
    • Saint-Geniez, M.1    D'Amore, P.A.2
  • 154
    • 34547671040 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor-A: not just for endothelial cells anymore
    • D'Amore, P. A. (2007) Vascular endothelial cell growth factor-A: not just for endothelial cells anymore. Am. J. Pathol. 171, 14-18
    • (2007) Am. J. Pathol. , vol.171 , pp. 14-18
    • D'Amore, P.A.1
  • 155
    • 42449154759 scopus 로고    scopus 로고
    • Visual acuity and multifocal electroretinographic changes after arteriovenous crossing sheathotomy for macular edema associated with branch retinal vein occlusion
    • Chung, E. J., Freeman, W. R. and Koh, H. J. (2008) Visual acuity and multifocal electroretinographic changes after arteriovenous crossing sheathotomy for macular edema associated with branch retinal vein occlusion. Retina 28, 220-225
    • (2008) Retina , vol.28 , pp. 220-225
    • Chung, E.J.1    Freeman, W.R.2    Koh, H.J.3
  • 156
    • 48449106803 scopus 로고    scopus 로고
    • Prognostic factors for visual outcome after intravitreal bevacizumab for macular edema due to branch retinal vein occlusion
    • Chung, E. J., Hong, Y. T., Lee, S. C., Kwon, O. W. and Koh, H. J. (2008) Prognostic factors for visual outcome after intravitreal bevacizumab for macular edema due to branch retinal vein occlusion. Graefes Arch. Clin. Exp. Ophthalmol. 246, 1241-1247
    • (2008) Graefes Arch. Clin. Exp. Ophthalmol. , vol.246 , pp. 1241-1247
    • Chung, E.J.1    Hong, Y.T.2    Lee, S.C.3    Kwon, O.W.4    Koh, H.J.5
  • 157
    • 84864149171 scopus 로고    scopus 로고
    • A brief history of anti-VEGF for the treatment of ocular angiogenesis
    • Kim, L. A. and D'Amore, P. A. (2012) A brief history of anti-VEGF for the treatment of ocular angiogenesis. Am. J. Pathol. 181, 376-379
    • (2012) Am. J. Pathol. , vol.181 , pp. 376-379
    • Kim, L.A.1    D'Amore, P.A.2
  • 160
    • 72549115279 scopus 로고    scopus 로고
    • Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity
    • Malhotra, D., Thimmulappa, R., Vij, N., Navas-Acien, A., Sussan, T., Merali, S., Zhang, L., Kelsen, S. G., Myers, A., Wise, R. et al. (2009) Heightened endoplasmic reticulum stress in the lungs of patients with chronic obstructive pulmonary disease: the role of Nrf2-regulated proteasomal activity. Am. J. Respir. Crit. Care Med 180, 1196-1207
    • (2009) Am. J. Respir. Crit. Care Med , vol.180 , pp. 1196-1207
    • Malhotra, D.1    Thimmulappa, R.2    Vij, N.3    Navas-Acien, A.4    Sussan, T.5    Merali, S.6    Zhang, L.7    Kelsen, S.G.8    Myers, A.9    Wise, R.10
  • 161
    • 57349151482 scopus 로고    scopus 로고
    • Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease
    • Suzuki, M., Betsuyaku, T., Ito, Y., Nagai, K., Nasuhara, Y., Kaga, K., Kondo, S. and Nishimura, M. (2008) Down-regulated NF-E2-related factor 2 in pulmonary macrophages of aged smokers and patients with chronic obstructive pulmonary disease. Am. J. Respir. Cell Mol. Biol. 39, 673-682
    • (2008) Am. J. Respir. Cell Mol. Biol. , vol.39 , pp. 673-682
    • Suzuki, M.1    Betsuyaku, T.2    Ito, Y.3    Nagai, K.4    Nasuhara, Y.5    Kaga, K.6    Kondo, S.7    Nishimura, M.8
  • 163
    • 84855411960 scopus 로고    scopus 로고
    • Beyond AREDS: is there a place for antioxidant therapy in the prevention/treatment of eye disease?
    • Kowluru, R. A. and Zhong, Q. (2011) Beyond AREDS: is there a place for antioxidant therapy in the prevention/treatment of eye disease? Invest. Ophthalmol. Visual Sci. 52, 8665-8671
    • (2011) Invest. Ophthalmol. Visual Sci. , vol.52 , pp. 8665-8671
    • Kowluru, R.A.1    Zhong, Q.2
  • 165
    • 0033621686 scopus 로고    scopus 로고
    • Increased H2O2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat
    • Ellis, E. A., Guberski, D. L., Somogyi-Mann, M. and Grant, M. B. (2000) Increased H2O2, vascular endothelial growth factor and receptors in the retina of the BBZ/Wor diabetic rat. Free Radical Biol. Med. 28, 91-101
    • (2000) Free Radical Biol. Med. , vol.28 , pp. 91-101
    • Ellis, E.A.1    Guberski, D.L.2    Somogyi-Mann, M.3    Grant, M.B.4
  • 166
    • 0036334679 scopus 로고    scopus 로고
    • Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat
    • Ellis, E. A., Guberski, D. L., Hutson, B. and Grant, M. B. (2002) Time course of NADH oxidase, inducible nitric oxide synthase and peroxynitrite in diabetic retinopathy in the BBZ/WOR rat. Nitric Oxide 6, 295-304
    • (2002) Nitric Oxide , vol.6 , pp. 295-304
    • Ellis, E.A.1    Guberski, D.L.2    Hutson, B.3    Grant, M.B.4
  • 170
    • 0035750902 scopus 로고    scopus 로고
    • Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study
    • Giusti, C., Forte, R., Vingolo, E. M. and Gargiulo, P. (2001) Is acetazolamide effective in the treatment of diabetic macular edema? A pilot study. Int. Ophthalmol. 24, 79-88
    • (2001) Int. Ophthalmol. , vol.24 , pp. 79-88
    • Giusti, C.1    Forte, R.2    Vingolo, E.M.3    Gargiulo, P.4
  • 171
    • 84875580877 scopus 로고    scopus 로고
    • Identification of a VEGF-independent and plasma kallikrein-kinin-dependent pathway of retinal vascular permeability in diabetic macular edema
    • Kita, T., Clermont, A. C., Fujisawa, K., Ishibashi, T., Aiello, L. P. and Feener, E. P. (2012) Identification of a VEGF-independent and plasma kallikrein-kinin-dependent pathway of retinal vascular permeability in diabetic macular edema. Invest. Ophthalmol. Visual Sci. 2431, A526
    • (2012) Invest. Ophthalmol. Visual Sci. , vol.2431
    • Kita, T.1    Clermont, A.C.2    Fujisawa, K.3    Ishibashi, T.4    Aiello, L.P.5    Feener, E.P.6
  • 172
    • 2042535361 scopus 로고    scopus 로고
    • Manipulating angiogenesis in medicine
    • Carmeliet, P. (2004) Manipulating angiogenesis in medicine. J. Intern. Med. 255, 538-561
    • (2004) J. Intern. Med. , vol.255 , pp. 538-561
    • Carmeliet, P.1
  • 174
    • 0031946192 scopus 로고    scopus 로고
    • The 67-kd laminin receptor is preferentially expressed by proliferating retinal vessels in a murine model of ischemic retinopathy
    • Stitt, A. W., McKenna, D., Simpson, D. A., Gardiner, T. A., Harriott, P., Archer, D. B. and Nelson, J. (1998) The 67-kd laminin receptor is preferentially expressed by proliferating retinal vessels in a murine model of ischemic retinopathy. Am. J. Pathol. 152, 1359-1365
    • (1998) Am. J. Pathol. , vol.152 , pp. 1359-1365
    • Stitt, A.W.1    McKenna, D.2    Simpson, D.A.3    Gardiner, T.A.4    Harriott, P.5    Archer, D.B.6    Nelson, J.7
  • 175
    • 0034125483 scopus 로고    scopus 로고
    • The expression of membrane-associated 67-kDa laminin receptor (67LR) is modulated in vitro by cell-contact inhibition
    • Donaldson, E. A., McKenna, D. J., McMullen, C. B., Scott, W. N., Stitt, A. W. and Nelson, J. (2000) The expression of membrane-associated 67-kDa laminin receptor (67LR) is modulated in vitro by cell-contact inhibition. Mol. Cell. Biol. Res. Comm. 3, 53-59
    • (2000) Mol. Cell. Biol. Res. Comm. , vol.3 , pp. 53-59
    • Donaldson, E.A.1    McKenna, D.J.2    McMullen, C.B.3    Scott, W.N.4    Stitt, A.W.5    Nelson, J.6
  • 176
    • 0034780124 scopus 로고    scopus 로고
    • Expression of the 67 kDa laminin receptor (67LR) during retinal development: correlations with angiogenesis
    • McKenna, D. J., Simpson, D. A., Feeney, S., Gardiner, T. A., Boyle, C., Nelson, J. and Stitt, A. W. (2001) Expression of the 67 kDa laminin receptor (67LR) during retinal development: correlations with angiogenesis. Exp. Eye Res. 73, 81-92
    • (2001) Exp. Eye Res. , vol.73 , pp. 81-92
    • McKenna, D.J.1    Simpson, D.A.2    Feeney, S.3    Gardiner, T.A.4    Boyle, C.5    Nelson, J.6    Stitt, A.W.7
  • 177
    • 13244257265 scopus 로고    scopus 로고
    • Inhibition of tumor necrosis factor-a improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy
    • Gardiner, T. A., Gibson, D. S., de Gooyer, T. E., de la Cruz, V. F., McDonald, D. M. and Stitt, A. W. (2005) Inhibition of tumor necrosis factor-a improves physiological angiogenesis and reduces pathological neovascularization in ischemic retinopathy. Am. J. Pathol. 166, 637-644
    • (2005) Am. J. Pathol. , vol.166 , pp. 637-644
    • Gardiner, T.A.1    Gibson, D.S.2    de Gooyer, T.E.3    de la Cruz, V.F.4    McDonald, D.M.5    Stitt, A.W.6
  • 178
    • 50249141649 scopus 로고    scopus 로고
    • The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies
    • Medina, R. J., O'Neill, C. L., Devine, A. B., Gardiner, T. A. and Stitt, A. W. (2008) The pleiotropic effects of simvastatin on retinal microvascular endothelium has important implications for ischaemic retinopathies. PLoS ONE 3, e2584
    • (2008) PLoS ONE , vol.3
    • Medina, R.J.1    O'Neill, C.L.2    Devine, A.B.3    Gardiner, T.A.4    Stitt, A.W.5
  • 180
    • 38849162389 scopus 로고    scopus 로고
    • Erythropoietin deficiency decreases vascular stability in mice
    • Chen, J., Connor, K. M., Aderman, C. M. and Smith, L. E. (2008) Erythropoietin deficiency decreases vascular stability in mice. J. Clin. Invest. 118, 526-533
    • (2008) J. Clin. Invest. , vol.118 , pp. 526-533
    • Chen, J.1    Connor, K.M.2    Aderman, C.M.3    Smith, L.E.4
  • 181
    • 80755152818 scopus 로고    scopus 로고
    • Intervention with an erythropoietin-derived peptide protects against neuroglial and vascular degeneration during diabetic retinopathy
    • McVicar, C. M., Hamilton, R., Colhoun, L. M., Gardiner, T. A., Brines, M., Cerami, A. and Stitt, A. W. (2011) Intervention with an erythropoietin-derived peptide protects against neuroglial and vascular degeneration during diabetic retinopathy. Diabetes 60, 2995-3005
    • (2011) Diabetes , vol.60 , pp. 2995-3005
    • McVicar, C.M.1    Hamilton, R.2    Colhoun, L.M.3    Gardiner, T.A.4    Brines, M.5    Cerami, A.6    Stitt, A.W.7
  • 182
    • 33847346061 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes
    • Thum, T., Fraccarollo, D., Schultheiss, M., Froese, S., Galuppo, P., Widder, J. D., Tsikas, D., Ertl, G. and Bauersachs, J. (2007) Endothelial nitric oxide synthase uncoupling impairs endothelial progenitor cell mobilization and function in diabetes. Diabetes 56, 666-674
    • (2007) Diabetes , vol.56 , pp. 666-674
    • Thum, T.1    Fraccarollo, D.2    Schultheiss, M.3    Froese, S.4    Galuppo, P.5    Widder, J.D.6    Tsikas, D.7    Ertl, G.8    Bauersachs, J.9
  • 183
    • 84865246962 scopus 로고    scopus 로고
    • Therapeutic revascularisation of ischaemic tissue: the opportunities and challenges for therapy using vascular stem/progenitor cells
    • O'Neill, C. L., O'Doherty, M. T., Wilson, S. E., Rana, A. A., Hirst, C. E., Stitt, A. W. and Medina, R. J. (2012) Therapeutic revascularisation of ischaemic tissue: the opportunities and challenges for therapy using vascular stem/progenitor cells. Stem Cell Res. Ther. 3, 31
    • (2012) Stem Cell Res. Ther. , vol.3 , pp. 31
    • O'Neill, C.L.1    O'Doherty, M.T.2    Wilson, S.E.3    Rana, A.A.4    Hirst, C.E.5    Stitt, A.W.6    Medina, R.J.7
  • 184
    • 0242270762 scopus 로고    scopus 로고
    • Involvement of progenitor cells in vascular repair
    • Hibbert, B., Olsen, S. and O'Brien, E. (2003) Involvement of progenitor cells in vascular repair. Trends Cardiovasc. Med. 13, 322-326
    • (2003) Trends Cardiovasc. Med. , vol.13 , pp. 322-326
    • Hibbert, B.1    Olsen, S.2    O'Brien, E.3
  • 188
    • 0037180517 scopus 로고    scopus 로고
    • Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures
    • Tepper, O. M., Galiano, R. D., Capla, J. M., Kalka, C., Gagne, P. J., Jacobowitz, G. R., Levine, J. P. and Gurtner, G. C. (2002) Human endothelial progenitor cells from type II diabetics exhibit impaired proliferation, adhesion, and incorporation into vascular structures. Circulation 106, 2781-2786
    • (2002) Circulation , vol.106 , pp. 2781-2786
    • Tepper, O.M.1    Galiano, R.D.2    Capla, J.M.3    Kalka, C.4    Gagne, P.J.5    Jacobowitz, G.R.6    Levine, J.P.7    Gurtner, G.C.8
  • 189
    • 40949149525 scopus 로고    scopus 로고
    • In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony-forming cell numbers and function
    • Ingram, D. A., Lien, I. Z., Mead, L. E., Estes, M., Prater, D. N., Derr-Yellin, E., DiMeglio, L. A. and Haneline, L. S. (2008) In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony-forming cell numbers and function. Diabetes 57, 724-731
    • (2008) Diabetes , vol.57 , pp. 724-731
    • Ingram, D.A.1    Lien, I.Z.2    Mead, L.E.3    Estes, M.4    Prater, D.N.5    Derr-Yellin, E.6    DiMeglio, L.A.7    Haneline, L.S.8
  • 191
    • 44749087657 scopus 로고    scopus 로고
    • Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes
    • Egan, C. G., Lavery, R., Caporali, F., Fondelli, C., Laghi-Pasini, F., Dotta, F. and Sorrentino, V. (2008) Generalised reduction of putative endothelial progenitors and CXCR4-positive peripheral blood cells in type 2 diabetes. Diabetologia 51, 1296-1305
    • (2008) Diabetologia , vol.51 , pp. 1296-1305
    • Egan, C.G.1    Lavery, R.2    Caporali, F.3    Fondelli, C.4    Laghi-Pasini, F.5    Dotta, F.6    Sorrentino, V.7
  • 192
    • 33846969572 scopus 로고    scopus 로고
    • Endothelial progenitor cells in cardiovascular disorders
    • Shantsila, E., Watson, T. and Lip, G. Y. (2007) Endothelial progenitor cells in cardiovascular disorders. J. Am. Coll. Cardiol. 49, 741-752
    • (2007) J. Am. Coll. Cardiol. , vol.49 , pp. 741-752
    • Shantsila, E.1    Watson, T.2    Lip, G.Y.3
  • 194
    • 1942425164 scopus 로고    scopus 로고
    • Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina
    • Dorrell, M. I., Otani, A., Aguilar, E., Moreno, S. K. and Friedlander, M. (2004) Adult bone marrow-derived stem cells use R-cadherin to target sites of neovascularization in the developing retina. Blood 103, 3420-3427
    • (2004) Blood , vol.103 , pp. 3420-3427
    • Dorrell, M.I.1    Otani, A.2    Aguilar, E.3    Moreno, S.K.4    Friedlander, M.5
  • 196
    • 79954670484 scopus 로고    scopus 로고
    • Outgrowth endothelial cells: characterization and their potential for reversing ischemic retinopathy
    • Medina, R. J., O'Neill, C. L., Humphreys, M. W., Gardiner, T. A. and Stitt, A. W. (2010) Outgrowth endothelial cells: characterization and their potential for reversing ischemic retinopathy. Invest. Ophthalmol. Visual Sci. 51, 5906-5913
    • (2010) Invest. Ophthalmol. Visual Sci. , vol.51 , pp. 5906-5913
    • Medina, R.J.1    O'Neill, C.L.2    Humphreys, M.W.3    Gardiner, T.A.4    Stitt, A.W.5
  • 197
    • 84858785425 scopus 로고    scopus 로고
    • Myeloid angiogenic cells act as alternative M2 macrophages and modulate angiogenesis through interleukin-8
    • Medina, R. J., O'Neill, C. L., O'Doherty, T. M., Knott, H., Guduric-Fuchs, J., Gardiner, T. A. and Stitt, A. W. (2011) Myeloid angiogenic cells act as alternative M2 macrophages and modulate angiogenesis through interleukin-8. Mol. Med. 17, 1045-1055
    • (2011) Mol. Med. , vol.17 , pp. 1045-1055
    • Medina, R.J.1    O'Neill, C.L.2    O'Doherty, T.M.3    Knott, H.4    Guduric-Fuchs, J.5    Gardiner, T.A.6    Stitt, A.W.7
  • 198
    • 0036732459 scopus 로고    scopus 로고
    • Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis
    • Otani, A., Kinder, K., Ewalt, K., Otero, F. J., Schimmel, P. and Friedlander, M. (2002) Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis. Nat. Med. 8, 1004-1010
    • (2002) Nat. Med. , vol.8 , pp. 1004-1010
    • Otani, A.1    Kinder, K.2    Ewalt, K.3    Otero, F.J.4    Schimmel, P.5    Friedlander, M.6
  • 199
    • 16444377000 scopus 로고    scopus 로고
    • Obese diabetic mouse environment differentially affects primitive and monocytic endothelial cell progenitors
    • Awad, O., Jiao, C., Ma, N., Dunnwald, M. and Schatteman, G. C. (2005) Obese diabetic mouse environment differentially affects primitive and monocytic endothelial cell progenitors. Stem Cells 23, 575-583
    • (2005) Stem Cells , vol.23 , pp. 575-583
    • Awad, O.1    Jiao, C.2    Ma, N.3    Dunnwald, M.4    Schatteman, G.C.5
  • 203
    • 80053561101 scopus 로고    scopus 로고
    • Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132
    • Katare, R., Riu, F., Mitchell, K., Gubernator, M., Campagnolo, P., Cui, Y., Fortunato, O., Avolio, E., Cesselli, D., Beltrami, A. P. et al. (2011) Transplantation of human pericyte progenitor cells improves the repair of infarcted heart through activation of an angiogenic program involving micro-RNA-132. Circ. Res. 109, 894-906
    • (2011) Circ. Res. , vol.109 , pp. 894-906
    • Katare, R.1    Riu, F.2    Mitchell, K.3    Gubernator, M.4    Campagnolo, P.5    Cui, Y.6    Fortunato, O.7    Avolio, E.8    Cesselli, D.9    Beltrami, A.P.10


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