Glial reactivity and impaired glutamate metabolism in short-term experimental diabetic retinopathy

Diabetes

Volumn 47, Issue 5, 1998, Pages 815-820

  Lieth, Erich ^a,c   Barber, Alistair J ^a   Xu, Baiyang ^a   Dice, Chelsea ^a,b   Ratz, Michael J ^a   Tanase, Diana ^a   Strother, John M ^a  

^a PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^b DICKINSON COLLEGE   (United States)

^c PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMIC ACID;

AMINO ACID METABOLISM; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL METABOLISM; CONTROLLED STUDY; DIABETIC RETINOPATHY; ELECTRORETINOGRAPHY; GLIA CELL; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MUELLER CELL; NERVE DEGENERATION; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; RETINA BLOOD VESSEL; STREPTOZOCIN DIABETES;

ACUTE DISEASE; ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC RETINOPATHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIAL FIBRILLARY ACIDIC PROTEIN; GLUTAMIC ACID; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; NEUROGLIA; RATS; RATS, SPRAGUE-DAWLEY; RETINA;

EID: 0031919598     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.47.5.815     Document Type: Article

References (40)

1. Klein R. Klein BEK, Moss SE, Crickshanks KJ: The Wisconsin Epidemiologic Study of Diabetic Retinopathy. XV. The long-term incidence of macular edema. Ophthalmology 102:7-16, 1995
2. Engerman RL, Kern TS: Retinopathy in animal models of diabetes. Diabetes Metab Rev 11:109-20, 1995
3. Daley M, Watzke R, Riddle M: Early loss of blue-sensitive color vision in patients with type 1 diabetes. Diabetes Care 10:777-81, 1987
4. Roy M, Gunkel R, Podgor M: Color vision defects in early diabetic retinopathy. Arch Ophthalmol 104:225-228, 1986
5. Sokol S, Moskowitz A, Skarf B: Contrast sensitivity in diabetics with and without background retinopathy. Arch Ophthalmol 103:51-54, 1985
6. Hirsh J, Puklin J: Reduced contrast sensitivity may precede clinically observable retinopathy in type 1 diabetes. In Acta XXIV International Congress of Ophthalmology San Francisco, 1982. P. Henkind, Ed. New York, Lippincott, 1083, p. 719-724
7. Coupland SG: Comparison of oscillatory potential and pattern electroretinogram measures in diabetic retinopathy. Doc Ophthalmol 66:207-218, 1987
8. Sakai H, Tani Y, Shirasawa E, Shirao Y, Kawasaki K: Development of electroretinographic alterations in streptozotocin-induced diabetes. Ophthalmic Res 27:57-63, 1995
9. Bresnick G: Diabetic retinopathy viewed as a neurosensory disorder. Arch Ophthalmol 104:989-990, 1986
10. Newman E, Reichenbach A: The Müller cell: a functional element of the retina. TINS 19:307-311, 1996
11. Gardner TW, Lieth E, Khin SA, Barber AJ, Bonsall DJ, Lesher T, Rice K, Brennan WA: Astrocytes increase barrier function and ZO-1 protein expression in cultured retinal capillary endothelial cells. Invest Ophthalmol Vis Sci 38:2423-2427, 1997
12. Rubin LL, Hall DE, Porter S, Barbu K, Cannon C, Horner HC, Janatpour M, Liaw CW, Manning K, Morales J, Tanner LI, Tomaselli KJ, Bard F: A cell culture model of the blood-brain barrier. J Cell Biol 115:1725-1735, 1991
13. Romano C, Price MT, Olney JW: Delayed excitotoxic neurodegeneration induced by excitatory amino acid agonists in isolated retina. J Neurochem 65:59-67, 1995
14. Riepe RE, Norenburg MD: Müller cell localization of glutamine synthetase in rat retina. Nature 268:654-655, 1977
15. Ohira A, de Juan E: Characterization of glial involvement in proliferative diabetic retinopathy. Ophthalmologica 210:187-195, 1990
16. Lieth E, LaNoue K, Gardner T, Barber A, Khin S: Glial cell function changes in rat retina with diabetes (Abstract). Diabetes 46 (Suppl. 1):129A, 1997
17. O'Callaghan JP: Quantification of glial fibrillary acidic protein: comparison of slot-immunobinding assays with a novel sandwich ELISA. Neurotoxical Teratol 13:275-281, 1991
18. Barber AJ, Lieth E: Agrin accumulates in the brain microvascular basal lamina during development of the blood-brain barrier. Dev Dyn 208:62-74, 1997
19. Levison SW, Goldman JE: Both oligodendrocytes and astrocytes develop from progenitors in the subventricular zone of postnatal rat forebrain. Neuron 10:201-212, 1993
20. Young G, Levison SW: Persistence of multipotential progenitors in the juvenile rat subventricular zone. Dev Neurosci 18:255-265, 1996
21. Gamberino WC, Berkich DA, Lynch CJ, Xu B, LaNoue KF: Role of pyruvate carboxylase in facilitation of synthesis of glutamate and glutamine in cultured astrocytes. J Neurochem 69:2312-2325, 1997
22. Eddleston M, Mucke L: Molecular profile of reactive astrocytes: implications for their role in neurologic disease. Neuroscience 54:15-36, 1993
23. Huxlin KR, Dreher Z, Schulz M, Dreher B: Glial reactivity in the retina of adult rats. Glia 15:105-118, 1995
24. Nakamura Y, Takeda M, Aimoto S, Hojo H, Takao T, Shimonishi Y, Hariguchi S, Nishimura T: Assembly regulation domain of glial fibrillary acidic protein: a single phospholrylation site diminishes its assembly-accelerating property. J Biol Chem 267:23269-23274, 1992
25. Vorwerk CK, Lipton SA, Zurakowski D, Hyman BT, Sabel BA, Dreyer EB: Chronic low-dose glutamate is toxic to retinal ganglion cells: toxicity blocked by memantine. Invest Ophthalmol Vis Sci 37:1618-1624, 1996
26. Osborne NN, Larsen AK: Antigens associated with specific retinal cells are affected by ischaemia caused by raised intraocular pressure: effect of glutamate antagonists. Neurochem Int 29:263-270, 1996
27. Balasingam V, Tejada-Berges T, Wright E, Bouckova R, Yong VW: Reactive astrogliosis in the neonatal mouse brain and its modulation by cytokines. J Neurosci 14:846-856, 1994
28. Mizutani M, Gerhardinger C, Lorenzi M: Müller cell changes in human diabetic retinopathy. Diabetes 47:445-449, 1998
29. Mizutani M, Lorenzi M: Increased expression of BCL-2 in Müller glial cells in human diabetic retinopathy (Abstract). Diabetes 46 (Suppl. 1):129A, 1997
30. Hammes H-P, Federoff HJ, Brownlee M: Nerve growth factor prevents both neuroretinal programmed cell death and capillary pathology in experimental diabetes. Mol Med 1:527-534, 1995
31. Ambati J, Chalam KV, Chawla DK, D'Angio CT, Guillet E.G., Rose SJ, Vanderlinde RE, Ambati BK: Elevated gamma-aminobutyric acid, glutamate and vascular endothelial growth factor levels in the vitreous of patients with proliferative diabetic retinopathy. Arch Ophthalmol 115:1161-1166, 1997
32. Vilchis C, Salceda R: Effect of diabetes on levels and uptake of putative amino acid neurotransmitters in rat retina and retinal pigment epithelium. Neurochem Res 21:1167-1171, 1996
33. Lucas DR, Newhouse JP: The toxic effect of sodium L-glutamate on the inner layers of the retina. Am Med Assoc Arch Ophthalmol 58:193-201, 1957
34. Olney JW: Glutamate-induced retinal degeneration in neonatal mice: electron microscopy of the acutely evolving lesion. J Neuropathol Exp Neurol 28:455-474, 1969
35. Dreyer EB, Zurakowski D, Schumer RA, Podos SM, Lipton SA: Elevated glutamate in the vitreous body of humans and monkeys with glaucoma. Arch Ophthalmol 114:299-305, 1996
36. Tout S, Chan-Ling T, Hollander H, Stone J: The role of Müller cells in the formation of the blood-retinal barrier. Neurosci 55:291-301, 1993
37. Cunha-Vaz J, Faria de Abreu J, Campo A, Figo G: Early breakdown of the blood-retinal barrier in diabetes. Br J Ophthalmol 59:649-656, 1975
38. Gardiner TA, Stitt AW, Archer DB: Retinal vascular endothelial cell endocytosis increases in early diabetes. Lab Invest 72:439-444, 1995
39. Latov N, Nilaver G, Zimmerman EA, Johnson WG, Silverman AJ, Defendini R, Cote L: Fibrillary astrocytes proliferate in response to brain injury. Dev Biol 72:381-384, 1979
40. Uchihori Y, Puro DG: Glutamate as a neuron-to-glial signal for mitogenesis: role of glial N-methyl-D-aspartate receptors. Brain Res 613:212-220, 1993