Aptamers and their potential to selectively target aspects of EGF, Wnt/β-catenin and TGFβ-smad family signaling

International Journal of Molecular Sciences

Volumn 14, Issue 4, 2013, Pages 6690-6719

  Conidi, Andrea ^a   van den Berghe, Veronique ^a   Huylebroeck, Danny ^a  

^a UNIVERSITY OF LEUVEN   (Belgium)

Author keywords

catenin; Aptamers; EGF; Signal transduction; Smad; Smad interacting proteins; TGF ; Wnt

Indexed keywords

APTAMER; ARC 1905 APTAMER; ARC 19499; AS 1411; BETA CATENIN; DNA; E 10030 APTAMER; EGAPTIVON PEGOL; EPIDERMAL GROWTH FACTOR; GREEN FLUORESCENT PROTEIN; MEMBRANE PROTEIN; NOX A12; NOX E36; PEGAPTANIB; PEPTIDE APTAMER; PROTEIN OAZ; PROTEIN SKI; PROTEIN SNON; RANIBIZUMAB; SCAFFOLD PROTEIN; SMAD INTERACTING PROTEIN 1; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSMEMBRANE PROSTATE ANDROGEN INDUCED PROTEIN; TRASTUZUMAB; UNCLASSIFIED DRUG; WNT PROTEIN; ZINC FINGER PROTEIN;

ACUTE GRANULOCYTIC LEUKEMIA; BINDING AFFINITY; CHEMICAL MODIFICATION; CHRONIC INFLAMMATION; CLINICAL TRIAL (TOPIC); COMBINATORIAL CHEMISTRY; COMPLEX FORMATION; DIABETIC MACULAR EDEMA; DIABETIC RETINOPATHY; DOWN REGULATION; DRUG APPROVAL; DRUG SELECTIVITY; HEMOPHILIA; HUMAN; IMMUNOGENICITY; INTRACELLULAR SIGNALING; LIGAND BINDING; MALIGNANT NEOPLASTIC DISEASE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PATHOPHYSIOLOGY; PHASE 1 CLINICAL TRIAL (TOPIC); PHASE 2 CLINICAL TRIAL (TOPIC); PHASE 3 CLINICAL TRIAL (TOPIC); POLYMERASE CHAIN REACTION; PROTEIN BINDING; PROTEIN DNA BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; RNA SEQUENCE; SIGNAL TRANSDUCTION; SUBRETINAL NEOVASCULARIZATION; SYSTEMIC LUPUS ERYTHEMATOSUS; THROMBOTIC THROMBOCYTOPENIC PURPURA; UNSPECIFIED SIDE EFFECT; VON WILLEBRAND DISEASE; ANIMAL; DRUG EFFECTS; METABOLISM; TRANSLATIONAL RESEARCH; WNT SIGNALING PATHWAY;

ANIMALS; APTAMERS, PEPTIDE; EPIDERMAL GROWTH FACTOR; HUMANS; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TRANSLATIONAL MEDICAL RESEARCH; WNT SIGNALING PATHWAY;

EID: 84875449355     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms14046690     Document Type: Review

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